Tmem109 (transmembrane protein 109)

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Gene: Tmem109 (transmembrane protein 109) Mus musculus

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Symbol:

Tmem109

Name:

transmembrane protein 109

RGD ID:

1616777

MGI Page

MGI

Description:

Predicted to enable voltage-gated monoatomic cation channel activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Predicted to be located in nuclear membrane and sarcoplasmic reticulum membrane. Predicted to be part of monoatomic ion channel complex. Is expressed in central nervous system; early conceptus; retina; and secondary oocyte. Orthologous to human TMEM109 (transmembrane protein 109).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

1110006I15Rik; AA958958; C77652; mg23; mitsugumin-23; mitsugumin23; voltage-gated monoatomic cation channel TMEM109

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM109 (transmembrane protein 109)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Tmem109 (transmembrane protein 109)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem109 (transmembrane protein 109)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM109 (transmembrane protein 109)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM109 (transmembrane protein 109)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem109 (transmembrane protein 109)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM109 (transmembrane protein 109)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM109 (transmembrane protein 109)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem109 (transmembrane protein 109)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Tmem109 (transmembrane protein 109)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TMEM109 (transmembrane protein 109)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-9i23.15	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	10,848,021 - 10,859,107 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	10,848,024 - 10,859,365 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	10,870,657 - 10,881,743 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	10,870,660 - 10,882,001 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	10,945,150 - 10,956,233 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	10,937,705 - 10,948,788 (-)	NCBI		MGSCv36	mm8
Celera	19	11,563,729 - 11,574,942 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	7.29	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

leukocyte adhesion deficiency 3 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (ISO)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (EXP)

benzo[a]pyrene (EXP,ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (EXP,ISO)

cadmium dichloride (ISO)

captan (EXP)

carbon nanotube (EXP)

CGP 52608 (ISO)

chlorpyrifos (EXP)

clobetasol (EXP)

clozapine (ISO)

copper atom (ISO)

copper(0) (ISO)

Cuprizon (ISO)

cyproconazole (EXP)

dexamethasone (ISO)

dextran sulfate (EXP)

Dibutyl phosphate (ISO)

dioxygen (ISO)

diuron (ISO)

doxorubicin (ISO)

epoxiconazole (EXP)

folic acid (EXP)

folpet (EXP)

haloperidol (ISO)

indometacin (ISO)

ivermectin (ISO)

paracetamol (ISO)

pentachlorophenol (EXP)

pinostrobin (ISO)

propiconazole (EXP)

resveratrol (EXP)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

Soman (ISO)

tamoxifen (EXP)

tetrachloromethane (EXP)

thioacetamide (ISO)

thiram (ISO)

titanium dioxide (EXP)

valproic acid (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to gamma radiation (IBA,ISO)

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (IBA,IMP)

monoatomic cation transmembrane transport (IEA)

negative regulation of programmed cell death (ISO)

Cellular Component

endoplasmic reticulum (ISO)

monoatomic ion channel complex (IEA)

nuclear membrane (ISO)

nuclear outer membrane (IEA)

sarcoplasmic reticulum membrane (ISS)

Molecular Function

protein binding (IPI)

voltage-gated monoatomic cation channel activity (ISS)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased thymocyte apoptosis (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:9720923	PMID:10349636	PMID:10725249	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:14610273	PMID:15489334
PMID:15782199	PMID:16141072	PMID:16141073	PMID:16602821	PMID:16964442	PMID:18799693	PMID:20007998	PMID:20060811	PMID:20368287	PMID:21677750	PMID:21873635	PMID:23542032
PMID:26496610	PMID:28630041	PMID:30550785	PMID:32554809	PMID:38223925

Genomics

Comparative Map Data

Tmem109
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	10,848,021 - 10,859,107 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	10,848,024 - 10,859,365 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	10,870,657 - 10,881,743 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	10,870,660 - 10,882,001 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	10,945,150 - 10,956,233 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	10,937,705 - 10,948,788 (-)	NCBI		MGSCv36	mm8
Celera	19	11,563,729 - 11,574,942 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	7.29	NCBI

TMEM109
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	60,914,158 - 60,923,443 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	60,913,907 - 60,923,443 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	60,681,630 - 60,690,915 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	60,438,253 - 60,447,491 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	58,042,259 - 58,051,802 (+)	NCBI		Celera
Cytogenetic Map	11	q12.2	NCBI
HuRef	11	57,027,540 - 57,037,083 (+)	NCBI		HuRef
CHM1_1	11	60,547,675 - 60,557,219 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	60,865,308 - 60,874,594 (+)	NCBI		T2T-CHM13v2.0

Tmem109
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	216,944,516 - 216,955,091 (-)	NCBI		GRCr8
mRatBN7.2	1	207,519,628 - 207,530,245 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	207,519,624 - 207,530,215 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	215,894,466 - 215,905,041 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	222,955,182 - 222,965,747 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	215,648,854 - 215,659,431 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	226,925,114 - 226,935,710 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	226,925,117 - 226,935,689 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	233,990,663 - 234,001,279 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	213,368,573 - 213,379,148 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	213,527,004 - 213,537,578 (-)	NCBI
Celera	1	205,012,212 - 205,022,789 (-)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

Tmem109
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955511	5,562,206 - 5,565,267 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955511	5,557,322 - 5,564,866 (+)	NCBI	ChiLan1.0	ChiLan1.0

TMEM109
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	62,083,184 - 62,092,709 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	63,127,455 - 63,136,746 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	56,177,335 - 56,186,645 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	59,617,802 - 59,627,349 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	59,617,802 - 59,627,349 (+)	Ensembl	panpan1.1		panPan2

TMEM109
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	55,377,331 - 55,389,810 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	55,363,698 - 55,385,587 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	53,950,499 - 53,963,229 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	56,425,747 - 56,438,173 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	56,425,747 - 56,434,036 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	55,483,265 - 55,495,701 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	55,104,766 - 55,117,373 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	55,985,877 - 55,998,618 (-)	NCBI		UU_Cfam_GSD_1.0

Tmem109
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	11,895,525 - 11,912,018 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936581	2,009,162 - 2,019,426 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936581	2,009,357 - 2,019,381 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM109
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	10,828,652 - 10,837,062 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	10,828,644 - 10,837,124 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	10,372,979 - 10,382,064 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM109
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	12,924,736 - 12,934,755 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	12,924,606 - 12,934,810 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	110,293,096 - 110,302,880 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem109
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624926	278,541 - 285,934 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624926	278,602 - 285,772 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tmem109
350 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1804
Count of miRNA genes:	703
Interacting mature miRNAs:	915
Transcripts:	ENSMUST00000038128, ENSMUST00000128835, ENSMUST00000129052, ENSMUST00000133303, ENSMUST00000138897, ENSMUST00000144681, ENSMUST00000147699, ENSMUST00000151355
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142302	Nstr1_m	nerve sheath tumor resistance QTL 1 (mouse)			Not determined		19	1	22371338	Mouse
1301271	Datd_m	dopamine transporter density (mouse)			Not determined		19	1	32340234	Mouse
1300923	Bits4_m	bitterness sensitivity 4 (mouse)			Not determined		19	3323216	37323348	Mouse
11039522	Tbbr4_m	Trypanosoma brucei brucei response 4 (mouse)					19	5313326	39313470	Mouse
4142161	Drinksac2_m	drink saccharin 2 (mouse)			Not determined			1	20695286	Mouse
1357819	Tgct2_m	testicular germ cell tumor 2 (mouse)			Not determined		19	3328551	20539663	Mouse
1302019	Pgia23_m	proteoglycan induced arthritis 23 (mouse)			Not determined		19	9787453	43787602	Mouse
38455997	Cdtm2_m	CD62L+ CD8 TM cells 2 (mouse)					19	9977364	19977364	Mouse
4142406	Pbctlp1_m	peripheral blood cytotoxic T lymphocyte percentage 1 (mouse)			Not determined			1	32875174	Mouse
1300776	Lfp3_m	long free running period 3 (mouse)			Not determined		19	1	20328703	Mouse
1300904	Chab5_m	cholesterol absorption 5 (mouse)			Not determined		19	1653764	35653927	Mouse
26884385	Skwq14_m	skull length QTL 14, 16 week (mouse)					19	3250000	35877400	Mouse
1301800	Faq10_m	fluctuating asymmetry QTL 10 (mouse)			Not determined		19	3323216	37323348	Mouse
1300591	Pas3_m	pulmonary adenoma susceptibility 3 (mouse)			Not determined		19	3323216	37323348	Mouse
1302126	Skull26_m	skull morphology 26 (mouse)			Not determined		19	3323216	37323348	Mouse
1301228	Iba4_m	induction of brown adipocytes 4 (mouse)			Not determined		19	9305715	43305821	Mouse

Markers in Region

Tmem109

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	19	10,870,905 - 10,871,365	UniSTS	GRCm38
MGSCv37	19	10,945,395 - 10,945,855	UniSTS	GRCm37
Celera	19	11,563,974 - 11,564,434	UniSTS
Cytogenetic Map	19	A	UniSTS
cM Map	19		UniSTS

AA958958

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	19	10,870,748 - 10,870,886	UniSTS	GRCm38
MGSCv37	19	10,945,238 - 10,945,376	UniSTS	GRCm37
Celera	19	11,563,817 - 11,563,955	UniSTS
Cytogenetic Map	19	A	UniSTS
Whitehead/MRC_RH	19	117.57	UniSTS

RH126209

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	19	10,870,773 - 10,871,014	UniSTS	GRCm38
MGSCv37	19	10,945,263 - 10,945,504	UniSTS	GRCm37
Celera	19	11,563,842 - 11,564,083	UniSTS
Cytogenetic Map	19	A	UniSTS
Whitehead/MRC_RH	19	121.13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_134142	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006527317	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC132402	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003502	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK049148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK150779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK151850	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK152419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK165990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK180863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK194142	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK196648	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK211175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK215166	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC022997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC023901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC025033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC025815	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000038128 ⟹ ENSMUSP00000039529

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	10,848,024 - 10,859,365 (-)	Ensembl
GRCm38.p6 Ensembl	19	10,870,660 - 10,882,001 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000128835 ⟹ ENSMUSP00000122130

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	10,851,624 - 10,859,062 (-)	Ensembl
GRCm38.p6 Ensembl	19	10,874,260 - 10,881,698 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000129052

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	10,851,292 - 10,859,075 (-)	Ensembl
GRCm38.p6 Ensembl	19	10,873,928 - 10,881,711 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000133303 ⟹ ENSMUSP00000120261

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	10,849,214 - 10,857,734 (-)	Ensembl
GRCm38.p6 Ensembl	19	10,871,850 - 10,880,370 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000138897

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	10,849,498 - 10,852,101 (-)	Ensembl
GRCm38.p6 Ensembl	19	10,872,134 - 10,874,737 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000144681 ⟹ ENSMUSP00000116750

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	10,851,606 - 10,859,095 (-)	Ensembl
GRCm38.p6 Ensembl	19	10,874,242 - 10,881,731 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000147699 ⟹ ENSMUSP00000120662

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	10,849,553 - 10,859,365 (-)	Ensembl
GRCm38.p6 Ensembl	19	10,872,189 - 10,882,001 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000151355

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	10,857,866 - 10,859,062 (-)	Ensembl
GRCm38.p6 Ensembl	19	10,880,502 - 10,881,698 (-)	Ensembl

RefSeq Acc Id:

NM_134142 ⟹ NP_598903

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	19	10,848,024 - 10,859,107 (-)	NCBI
GRCm38	19	10,870,660 - 10,881,743 (-)	NCBI
MGSCv37	19	10,945,150 - 10,956,233 (-)	RGD
Celera	19	11,563,729 - 11,574,942 (-)	RGD
cM Map	19		ENTREZGENE

Sequence:

show sequence

CTATAAACCAACACCCCGGGAGTTGAGGCGCCGGTTTGGTGGCGCGTTTTCTAGCGAAGTCCCA
CGTGAAGGATAGCGGTGACCGGAGCAGGACACAAACATGGCAGGCGCACACAGCACTCCGTTAT
GGAGCAGACATCTGCTCAAAGCTGTCCTGATGGTCCTCGTGGCCCTTTTCCTCGTCCACTCCGC
ATCAGCCCAGTCTCATCGAGAGTTTGCCTCACCTGGTCAACAGAAGAAGGAGACCTCAGCTGAT
ATTTTGACCCAGATTGGCCGATCTCTGAAGGAGATGTTGGATACCTGGCTAGGGCCAGAGACCA
TGCATGTGATTTCAGAGACCCTGTTGCAGGTGATGTGGGCCATCTCATCAGCCATCTCTGTGGC
CTGCTTTGCCCTGTCTGGGATTGCTGCCCAGTTGCTGAGTGCCCTGGGGCTGGATGGTGAACAA
CTCACCCAGGGCTTGAAGCTCAGCCCTAGCCAAGTCCAGACCCTTCTACTGTGGGGAGCAGCAG
CACTGGTCATCTACTGGTTGCTGTCCCTGCTCCTAGGCTTGGTCTTGGCCTTGCTAGGGAGGAT
CCTGGGGGGTCTGAAACTTGTTCTTTTTGTCGCTGGCTTTGTGGCCCTGGTGAGGTCTGTGCCC
GACCCATCTACCCGGGCCTTGATGCTCTTGGCCTTGTTAACTCTCTTTGCCTTGCTGAGCCGGC
TCACTGGCTCCAGGAGCTCAGGGAGCCACCTGGAAGCCAAGGTGAGAGGGCTGGAGCGCCAGAT
AGAAGAGCTTAGAGGGAGGCAGAGGCGAGCAGCCAAGATGCCCAGGAGCATGGAAGAAGAGTGA
CAAGGGCGTCCCCAAGAGACACCCTCACCGTACCAAAGAGCTGAGCTGCTTCTGGGTCTCACGG
ACCTCCTTGCAGCCCCCTTGCCCTTTCCTTGCCTTGTGTCCGGAACCTTCACACCTTTACCCCT
GCGCTAGCCCCTGGCTGAGAGGAGAGAACCTGTCCTCTGCCGGTGCTCAGTCAAGTGATGGCTC
CCTGCCCTTCTGTGCTCCCAGCCTGCCTCCCCCAGGGCAGGTTGGAGCCCTCAGCCCTGGCTTC
TGCTCTCAGCCAGCACCACTGCCCGCTGATCTCCGTGATGATTAACCTGCTGCTTCCTTACACA
AGGCCTGCCCAGGCTGAAGCTCCTGTTTGACCACTCCCCCCCCCCCCCCCCAGCTCTTTTCTTC
CTGCTCCCAGCCACACTACCATCCCAAGTCCCTTGCGGCCCTCTCTGTCTTCCTCATTGCACTG
CAATGGGCAGGGGTAGGAGATTGGAGATAAGGATGAAGGGGGAGGAAAGGGTCCCTGGAGGCCT
GTGCATCTATGCTCTGTTACAAGTGCCTTAGCAGGAGTCAGCAGCACCCTCCAGGTGCCCCTTG
CCACACTGAATGTGGGAAAGTGTGCTGTGGCTACTTCGTGGTCAGAGTGAGCCCCTTGCAGAAT
CCCCACTCCAGCAAACAAAGCAACGGCCCTGCTGGGATTGTCGAATCTCCCTTGAGGGTTTCAG
GGACCTTGAAAAGGGCAGGAGGACCTGCTGTCTTGCAGTTTTACCCCTGTCCACTCTCTGCCAT
CCAGAAGCAAGCGTTGGTCAGTGTTGTGTCCCAGTAGCTGGGAAGGGCACGGCTTTGCCCTGAT
CTGTTCTGCAGGGCTAGGAGTGAGCCTGCCACTAACCCCTCTCCACCACTTGCTCACTCTTGGC
CTTGGCCTTGGCCTTTAGGTCCCTGGTGGAGGGAGATGACCCATGCCAGGTCCAGCACAAGATG
TGAAGATTAAATGCCTATTCTTACTGAAGGTTTGATGTGGAATCATGGCTGCAGTGATATGTTT
TTATCAGCGCTTGGTGGTTTTAAAGTGCATGCTATTTTATTATCTTCTTCTGAATAAAATGTAT
TTACTCAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006527317 ⟹ XP_006527380

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	19	10,848,021 - 10,858,136 (-)	NCBI
GRCm38	19	10,870,657 - 10,880,772 (-)	NCBI

Sequence:

show sequence

TTTGAACACAGTGCTTGCACAAATTATCTAACTTCTTGAAGTAACTCTTAACCCAGTTTCAACA
GAACTTACATTTGAGGAGATTGAATTTCAGATAGGTTAAGTAACAGGTGTAAAGGTAGTGGCGG
CTAACTTGTGATAGATCTGAACCTGTGTCCTTTGTACAGAGAGCTCTTAGGAGGCTTTGCTTAA
AGTAGACTTTTCTCTGCGTTGCTGATCTTTGCAACCACTGTTTGATTATGCCTCAGGAATCCTG
GGGAGCTTTAAAAACAAAACAAAAAGGCTGAGCTCCTCCCTGGGAGGGTCTGAGTGGGTTGCCT
GGGTGGGGCAAACACCCTTGTTTAACAGGCTAGTCAGGCAGGTCAGATGGGCAATCCAGAGTGA
GGATTGCAGATCCACAGGACTGCAGTGAGTAGTGAAGGAACCGTGGGGGCCAGCAGAGGGCACC
AAGTTAGTTCTTGCCCCTGTAGTGATTTATAGCGAGAAAGGAAAAAGAAGAGGAAGGAGCACTG
ACTGGAGGTAGTGTGGACAGCCCCACCCCGCCCTGGCAGAGCAAACCACAGCTGAACATAGAGT
GACGTCTCACCACCATAACACAAACATGGCAGGCGCACACAGCACTCCGTTATGGAGCAGACAT
CTGCTCAAAGCTGTCCTGATGGTCCTCGTGGCCCTTTTCCTCGTCCACTCCGCATCAGCCCAGT
CTCATCGAGAGTTTGCCTCACCTGGTCAACAGAAGAAGGAGACCTCAGCTGATATTTTGACCCA
GATTGGCCGATCTCTGAAGGAGATGTTGGATACCTGGCTAGGGCCAGAGACCATGCATGTGATT
TCAGAGACCCTGTTGCAGGTGATGTGGGCCATCTCATCAGCCATCTCTGTGGCCTGCTTTGCCC
TGTCTGGGATTGCTGCCCAGTTGCTGAGTGCCCTGGGGCTGGATGGTGAACAACTCACCCAGGG
CTTGAAGCTCAGCCCTAGCCAAGTCCAGACCCTTCTACTGTGGGGAGCAGCAGCACTGGTCATC
TACTGGTTGCTGTCCCTGCTCCTAGGCTTGGTCTTGGCCTTGCTAGGGAGGATCCTGGGGGGTC
TGAAACTTGTTCTTTTTGTCGCTGGCTTTGTGGCCCTGGTGAGGTCTGTGCCCGACCCATCTAC
CCGGGCCTTGATGCTCTTGGCCTTGTTAACTCTCTTTGCCTTGCTGAGCCGGCTCACTGGCTCC
AGGAGCTCAGGGAGCCACCTGGAAGCCAAGGTGAGAGGGCTGGAGCGCCAGATAGAAGAGCTTA
GAGGGAGGCAGAGGCGAGCAGCCAAGATGCCCAGGAGCATGGAAGAAGAGTGACAAGGGCGTCC
CCAAGAGACACCCTCACCGTACCAAAGAGCTGAGCTGCTTCTGGGTCTCACGGACCTCCTTGCA
GCCCCCTTGCCCTTTCCTTGCCTTGTGTCCGGAACCTTCACACCTTTACCCCTGCGCTAGCCCC
TGGCTGAGAGGAGAGAACCTGTCCTCTGCCGGTGCTCAGTCAAGTGATGGCTCCCTGCCCTTCT
GTGCTCCCAGCCTGCCTCCCCCAGGGCAGGTTGGAGCCCTCAGCCCTGGCTTCTGCTCTCAGCC
AGCACCACTGCCCGCTGATCTCCGTGATGATTAACCTGCTGCTTCCTTACACAAGGCCTGCCCA
GGCTGAAGCTCCTGTTTGACCACTCCCCCCCCCCCCCCCCAGCTCTTTTCTTCCTGCTCCCAGC
CACACTACCATCCCAAGTCCCTTGCGGCCCTCTCTGTCTTCCTCATTGCACTGCAATGGGCAGG
GGTAGGAGATTGGAGATAAGGATGAAGGGGGAGGAAAGGGTCCCTGGAGGCCTGTGCATCTATG
CTCTGTTACAAGTGCCTTAGCAGGAGTCAGCAGCACCCTCCAGGTGCCCCTTGCCACACTGAAT
GTGGGAAAGTGTGCTGTGGCTACTTCGTGGTCAGAGTGAGCCCCTTGCAGAATCCCCACTCCAG
CAAACAAAGCAACGGCCCTGCTGGGATTGTCGAATCTCCCTTGAGGGTTTCAGGGACCTTGAAA
AGGGCAGGAGGACCTGCTGTCTTGCAGTTTTACCCCTGTCCACTCTCTGCCATCCAGAAGCAAG
CGTTGGTCAGTGTTGTGTCCCAGTAGCTGGGAAGGGCACGGCTTTGCCCTGATCTGTTCTGCAG
GGCTAGGAGTGAGCCTGCCACTAACCCCTCTCCACCACTTGCTCACTCTTGGCCTTGGCCTTGG
CCTTTAGGTCCCTGGTGGAGGGAGATGACCCATGCCAGGTCCAGCACAAGATGTGAAGATTAAA
TGCCTATTCTTACTGAAGGTTTGATGTGGAATCATGGCTGCAGTGATATGTTTTTATCAGCGCT
TGGTGGTTTTAAAGTGCATGCTATTTTATTATCTTCTTCTGAATAAAATGTATTTACTCAAAAG
TC

hide sequence

Protein Sequences


Protein RefSeqs	NP_598903	(Get FASTA)	NCBI Sequence Viewer
	XP_006527380	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH22997	(Get FASTA)	NCBI Sequence Viewer
	AAH23901	(Get FASTA)	NCBI Sequence Viewer
	AAH25033	(Get FASTA)	NCBI Sequence Viewer
	AAH25815	(Get FASTA)	NCBI Sequence Viewer
	BAE29844	(Get FASTA)	NCBI Sequence Viewer
	BAE30740	(Get FASTA)	NCBI Sequence Viewer
	BAE31204	(Get FASTA)	NCBI Sequence Viewer
	BAE38505	(Get FASTA)	NCBI Sequence Viewer
	EDL41387	(Get FASTA)	NCBI Sequence Viewer
	EDL41388	(Get FASTA)	NCBI Sequence Viewer
	EDL41389	(Get FASTA)	NCBI Sequence Viewer
	EDL41390	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000039529
	ENSMUSP00000039529.9
	ENSMUSP00000116750.2
	ENSMUSP00000120261
	ENSMUSP00000120261.2
	ENSMUSP00000120662.2
	ENSMUSP00000122130.2
GenBank Protein	Q3UBX0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_598903 ⟸ NM_134142
- Peptide Label:	precursor
- UniProtKB:	Q8R006 (UniProtKB/Swiss-Prot), Q3UBX0 (UniProtKB/Swiss-Prot), D3Z0I8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAGAHSTPLWSRHLLKAVLMVLVALFLVHSASAQSHREFASPGQQKKETSADILTQIGRSLKEM LDTWLGPETMHVISETLLQVMWAISSAISVACFALSGIAAQLLSALGLDGEQLTQGLKLSPSQV QTLLLWGAAALVIYWLLSLLLGLVLALLGRILGGLKLVLFVAGFVALVRSVPDPSTRALMLLAL LTLFALLSRLTGSRSSGSHLEAKVRGLERQIEELRGRQRRAAKMPRSMEEE hide sequence

RefSeq Acc Id:	XP_006527380 ⟸ XM_006527317
- Peptide Label:	isoform X1
- UniProtKB:	Q8R006 (UniProtKB/Swiss-Prot), Q3UBX0 (UniProtKB/Swiss-Prot), D3Z0I8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAGAHSTPLWSRHLLKAVLMVLVALFLVHSASAQSHREFASPGQQKKETSADILTQIGRSLKEM LDTWLGPETMHVISETLLQVMWAISSAISVACFALSGIAAQLLSALGLDGEQLTQGLKLSPSQV QTLLLWGAAALVIYWLLSLLLGLVLALLGRILGGLKLVLFVAGFVALVRSVPDPSTRALMLLAL LTLFALLSRLTGSRSSGSHLEAKVRGLERQIEELRGRQRRAAKMPRSMEEE hide sequence

Ensembl Acc Id:

ENSMUSP00000116750 ⟸ ENSMUST00000144681

Ensembl Acc Id:

ENSMUSP00000120261 ⟸ ENSMUST00000133303

Ensembl Acc Id:

ENSMUSP00000120662 ⟸ ENSMUST00000147699

Ensembl Acc Id:

ENSMUSP00000122130 ⟸ ENSMUST00000128835

Ensembl Acc Id:

ENSMUSP00000039529 ⟸ ENSMUST00000038128

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q3UBX0-F1-model_v2	AlphaFold	Q3UBX0	1-243	view protein structure

Promoters

RGD ID:

13678940

Promoter ID:

EPDNEW_M23619

Type:

initiation region

Name:

Tmem109_1

Description:

Mus musculus transmembrane protein 109 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	19	10,881,746 - 10,881,806	EPDNEW

RGD ID:

6830477

Promoter ID:

MM_KWN:26403

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day3, BoneMarrow_0Hour, Lung

Transcripts:

OTTMUST00000082348

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	19	10,954,414 - 10,954,914 (-)	MPROMDB

RGD ID:

6830475

Promoter ID:

MM_KWN:26404

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

OTTMUST00000082345, OTTMUST00000082346, OTTMUST00000082347, OTTMUST00000082349, OTTMUST00000082350, OTTMUST00000082352

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	19	10,956,016 - 10,956,516 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1915789	AgrOrtholog
Ensembl Genes	ENSMUSG00000034659	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000038128	ENTREZGENE
	ENSMUST00000038128.15	UniProtKB/Swiss-Prot
	ENSMUST00000128835.8	UniProtKB/TrEMBL
	ENSMUST00000133303	ENTREZGENE
	ENSMUST00000133303.8	UniProtKB/TrEMBL
	ENSMUST00000144681.2	UniProtKB/TrEMBL
	ENSMUST00000147699.2	UniProtKB/TrEMBL
InterPro	TMEM109	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:68539	UniProtKB/Swiss-Prot
MGD	MGI:1915789	ENTREZGENE
NCBI Gene	68539	ENTREZGENE
PANTHER	PTHR14550	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 109	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	BRI3BP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Tmem109	PhenoGen
UniProt	D3YX08_MOUSE	UniProtKB/TrEMBL
	D3Z0I8	ENTREZGENE, UniProtKB/TrEMBL
	D3Z3Z2_MOUSE	UniProtKB/TrEMBL
	D3Z7P2_MOUSE	UniProtKB/TrEMBL
	Q3UBX0	ENTREZGENE
	Q8R006	ENTREZGENE
	TM109_MOUSE	UniProtKB/Swiss-Prot
UniProt Secondary	Q8R006	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Mammalian Phenotype