Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ttyh3 | Mouse | (+)-schisandrin B | multiple interactions | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TTYH3 mRNA] | CTD | PMID:31150632 | Ttyh3 | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TTYH3 mRNA | CTD | PMID:22206623 | Ttyh3 | Mouse | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of TTYH3 mRNA | CTD | PMID:22206623 | Ttyh3 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TTYH3 mRNA | CTD | PMID:22298810 | Ttyh3 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TTYH3 mRNA | CTD | PMID:34747641 | Ttyh3 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TTYH3 mRNA | CTD | PMID:21570461 and PMID:24680724 | Ttyh3 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TTYH3 mRNA | CTD | PMID:20106945 and PMID:21632981 | Ttyh3 | Mouse | 2-bromohexadecanoic acid | multiple interactions | ISO | TTYH3 (Homo sapiens) | 6480464 | 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of TTYH3 protein] | CTD | PMID:38195004 | Ttyh3 | Mouse | 2-methylcholine | affects expression | ISO | TTYH3 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of TTYH3 mRNA | CTD | PMID:21179406 | Ttyh3 | Mouse | 3,3',5,5'-tetrabromobisphenol A | decreases expression | EXP | | 6480464 | tetrabromobisphenol A results in decreased expression of TTYH3 mRNA | CTD | PMID:25172293 | Ttyh3 | Mouse | 4,4'-sulfonyldiphenol | decreases methylation | ISO | TTYH3 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of TTYH3 gene | CTD | PMID:31601247 | Ttyh3 | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of TTYH3 mRNA | CTD | PMID:36041667 | Ttyh3 | Mouse | 6-propyl-2-thiouracil | increases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of TTYH3 mRNA | CTD | PMID:30047161 | Ttyh3 | Mouse | acrylamide | decreases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of TTYH3 mRNA | CTD | PMID:28959563 | Ttyh3 | Mouse | acrylamide | decreases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of TTYH3 mRNA | CTD | PMID:32763439 | Ttyh3 | Mouse | aflatoxin B1 | increases methylation | ISO | TTYH3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of TTYH3 intron | CTD | PMID:30157460 | Ttyh3 | Mouse | all-trans-retinoic acid | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of TTYH3 mRNA | CTD | PMID:33167477 | Ttyh3 | Mouse | amitrole | increases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of TTYH3 mRNA | CTD | PMID:30047161 | Ttyh3 | Mouse | amosite asbestos | decreases methylation | ISO | TTYH3 (Homo sapiens) | 6480464 | Asbestos and Amosite results in decreased methylation of TTYH3 promoter | CTD | PMID:29626692 | Ttyh3 | Mouse | ampicillin | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Ampicillin results in increased expression of TTYH3 mRNA | CTD | PMID:21632981 | Ttyh3 | Mouse | antirheumatic drug | decreases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of TTYH3 mRNA | CTD | PMID:24449571 | Ttyh3 | Mouse | aristolochic acid A | decreases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TTYH3 protein | CTD | PMID:33212167 | Ttyh3 | Mouse | arsane | decreases ubiquitination | ISO | TTYH3 (Homo sapiens) | 6480464 | Arsenic results in decreased ubiquitination of TTYH3 protein | CTD | PMID:35994080 | Ttyh3 | Mouse | arsenic atom | decreases ubiquitination | ISO | TTYH3 (Homo sapiens) | 6480464 | Arsenic results in decreased ubiquitination of TTYH3 protein | CTD | PMID:35994080 | Ttyh3 | Mouse | benzatropine | multiple interactions | ISO | TTYH3 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in decreased expression of TTYH3 protein | CTD | PMID:34122009 | Ttyh3 | Mouse | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of TTYH3 mRNA | CTD | PMID:21569818 | Ttyh3 | Mouse | bisphenol A | decreases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of TTYH3 mRNA | CTD | PMID:25181051 | Ttyh3 | Mouse | bisphenol A | multiple interactions | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of TTYH3 mRNA | CTD | PMID:36041667 | Ttyh3 | Mouse | bisphenol A | affects expression | ISO | TTYH3 (Homo sapiens) | 6480464 | bisphenol A affects the expression of TTYH3 mRNA | CTD | PMID:30903817 | Ttyh3 | Mouse | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TTYH3 promoter | CTD | PMID:27312807 | Ttyh3 | Mouse | bisphenol A | increases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of TTYH3 mRNA | CTD | PMID:30816183 and PMID:34947998 | Ttyh3 | Mouse | Bisphenol B | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of TTYH3 protein | CTD | PMID:34186270 | Ttyh3 | Mouse | bisphenol F | multiple interactions | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of TTYH3 mRNA | CTD | PMID:36041667 | Ttyh3 | Mouse | buta-1,3-diene | decreases expression | EXP | | 6480464 | 1 and 3-butadiene results in decreased expression of TTYH3 mRNA | CTD | PMID:29038090 | Ttyh3 | Mouse | cadmium atom | multiple interactions | ISO | TTYH3 (Homo sapiens) | 6480464 | 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of TTYH3 protein] and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of TTYH3 protein | CTD | PMID:38195004 | Ttyh3 | Mouse | cadmium dichloride | multiple interactions | ISO | TTYH3 (Homo sapiens) | 6480464 | 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of TTYH3 protein] and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of TTYH3 protein | CTD | PMID:38195004 | Ttyh3 | Mouse | caffeine | decreases phosphorylation | ISO | TTYH3 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of TTYH3 protein | CTD | PMID:35688186 | Ttyh3 | Mouse | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of TTYH3 mRNA | CTD | PMID:37019170 | Ttyh3 | Mouse | cisplatin | multiple interactions | ISO | TTYH3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of TTYH3 mRNA | CTD | PMID:27392435 | Ttyh3 | Mouse | cisplatin | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TTYH3 mRNA | CTD | PMID:27392435 | Ttyh3 | Mouse | cobalt dichloride | decreases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of TTYH3 mRNA | CTD | PMID:19320972 | Ttyh3 | Mouse | copper atom | increases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | Copper results in increased expression of TTYH3 mRNA | CTD | PMID:30556269 | Ttyh3 | Mouse | copper(0) | increases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | Copper results in increased expression of TTYH3 mRNA | CTD | PMID:30556269 | Ttyh3 | Mouse | crocidolite asbestos | increases expression | EXP | | 6480464 | Asbestos and Crocidolite results in increased expression of TTYH3 mRNA | CTD | PMID:29279043 | Ttyh3 | Mouse | crocidolite asbestos | decreases methylation | ISO | TTYH3 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in decreased methylation of TTYH3 promoter | CTD | PMID:29626692 | Ttyh3 | Mouse | Cuprizon | multiple interactions | ISO | TTYH3 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in decreased expression of TTYH3 protein | CTD | PMID:34122009 | Ttyh3 | Mouse | cyclosporin A | decreases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TTYH3 mRNA | CTD | PMID:20106945 more ... | Ttyh3 | Mouse | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of TTYH3 mRNA | CTD | PMID:21266533 | Ttyh3 | Mouse | dicrotophos | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of TTYH3 mRNA | CTD | PMID:28302478 | Ttyh3 | Mouse | dimethylarsinic acid | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TTYH3 mRNA | CTD | PMID:34876320 | Ttyh3 | Mouse | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of TTYH3 mRNA | CTD | PMID:30319688 | Ttyh3 | Mouse | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of TTYH3 mRNA | CTD | PMID:30319688 | Ttyh3 | Mouse | ethyl methanesulfonate | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of TTYH3 mRNA | CTD | PMID:23649840 | Ttyh3 | Mouse | fluoranthene | multiple interactions | EXP | | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of TTYH3 mRNA | CTD | PMID:28329830 | Ttyh3 | Mouse | flutamide | decreases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | Flutamide results in decreased expression of TTYH3 mRNA | CTD | PMID:24136188 | Ttyh3 | Mouse | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of TTYH3 mRNA | CTD | PMID:25629700 | Ttyh3 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TTYH3 mRNA | CTD | PMID:22206623 | Ttyh3 | Mouse | FR900359 | increases phosphorylation | ISO | TTYH3 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of TTYH3 protein | CTD | PMID:37730182 | Ttyh3 | Mouse | gentamycin | decreases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of TTYH3 mRNA | CTD | PMID:22061828 | Ttyh3 | Mouse | maneb | multiple interactions | EXP | | 6480464 | [Maneb co-treated with Paraquat] results in increased expression of TTYH3 mRNA | CTD | PMID:36117858 | Ttyh3 | Mouse | methylarsonic acid | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TTYH3 mRNA | CTD | PMID:34876320 | Ttyh3 | Mouse | nefazodone | decreases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | nefazodone results in decreased expression of TTYH3 mRNA | CTD | PMID:24136188 | Ttyh3 | Mouse | nickel atom | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Nickel results in increased expression of TTYH3 mRNA | CTD | PMID:25583101 | Ttyh3 | Mouse | nickel sulfate | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of TTYH3 mRNA | CTD | PMID:16780908 | Ttyh3 | Mouse | paraquat | multiple interactions | EXP | | 6480464 | [Maneb co-treated with Paraquat] results in increased expression of TTYH3 mRNA | CTD | PMID:36117858 | Ttyh3 | Mouse | perfluorooctanoic acid | decreases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of TTYH3 protein | CTD | PMID:26879310 | Ttyh3 | Mouse | quercetin | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Quercetin results in increased expression of TTYH3 mRNA | CTD | PMID:21632981 | Ttyh3 | Mouse | quinolin-8-ol | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Oxyquinoline results in increased expression of TTYH3 mRNA | CTD | PMID:21632981 | Ttyh3 | Mouse | SB 431542 | multiple interactions | ISO | TTYH3 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of TTYH3 protein | CTD | PMID:37664457 | Ttyh3 | Mouse | sodium arsenate | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TTYH3 mRNA | CTD | PMID:34876320 | Ttyh3 | Mouse | sodium arsenite | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TTYH3 mRNA | CTD | PMID:34876320 | Ttyh3 | Mouse | sulfadimethoxine | increases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of TTYH3 mRNA | CTD | PMID:30047161 | Ttyh3 | Mouse | sunitinib | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of TTYH3 mRNA | CTD | PMID:31533062 | Ttyh3 | Mouse | temozolomide | increases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of TTYH3 mRNA | CTD | PMID:31758290 | Ttyh3 | Mouse | tetrachloromethane | decreases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of TTYH3 mRNA | CTD | PMID:31150632 | Ttyh3 | Mouse | tetrachloromethane | multiple interactions | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TTYH3 mRNA] | CTD | PMID:31150632 | Ttyh3 | Mouse | titanium dioxide | affects expression | EXP | | 6480464 | titanium dioxide affects the expression of TTYH3 mRNA | CTD | PMID:23557971 | Ttyh3 | Mouse | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of TTYH3 mRNA | CTD | PMID:30912803 | Ttyh3 | Mouse | tunicamycin | decreases expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of TTYH3 mRNA | CTD | PMID:22378314 | Ttyh3 | Mouse | valproic acid | increases methylation | ISO | TTYH3 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TTYH3 gene | CTD | PMID:29154799 | Ttyh3 | Mouse | valproic acid | affects expression | ISO | TTYH3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TTYH3 mRNA | CTD | PMID:25979313 | Ttyh3 | Mouse | vinclozolin | increases expression | ISO | Ttyh3 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of TTYH3 mRNA | CTD | PMID:23034163 | |