Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gabra1 (gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1) Mus musculus
Analyze
Symbol: Gabra1
Name: gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
Description: Exhibits transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Contributes to GABA-gated chloride ion channel activity. Involved in inhibitory synapse assembly and regulation of postsynaptic membrane potential. Localizes to GABA-ergic synapse and plasma membrane. Is expressed in alimentary system; central nervous system; and eye. Used to study idiopathic generalized epilepsy. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 19 and idiopathic generalized epilepsy 13. Orthologous to human GABRA1 (gamma-aminobutyric acid type A receptor subunit alpha1); INTERACTS WITH bisphenol A; butan-1-ol; clozapine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GABA(A) receptor subunit alpha-1; GABAA alpha 1; GABAA-alpha1; GABAAR alpha1; GABAAR-alpha1; Gabra-1; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1; gamma-aminobutyric acid receptor subunit alpha-1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1142,130,939 - 42,182,930 (-)EnsemblGRCm38mm10GRCm38
GRCm381142,130,939 - 42,183,066 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371141,944,982 - 41,996,432 (-)NCBIGRCm37mm9NCBIm37
MGSCv361141,974,903 - 42,026,353 (-)NCBImm8
Celera1145,953,528 - 46,009,149 (-)NCBICelera
Cytogenetic Map11A5NCBI
cM Map1124.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gabra1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62147
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.