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Gene: Slc6a8 (solute carrier family 6 (neurotransmitter transporter, creatine), member 8) Mus musculus
Symbol: Slc6a8
Name: solute carrier family 6 (neurotransmitter transporter, creatine), member 8
Description: Predicted to have cation transmembrane transporter activity and neurotransmitter binding activity. Predicted to be involved in creatine transmembrane transport. Predicted to localize to glutamatergic synapse; integral component of postsynaptic membrane; and neuron projection. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study creatine transporter deficiency. Human ortholog(s) of this gene implicated in creatine transporter deficiency and intellectual disability. Orthologous to human SLC6A8 (solute carrier family 6 member 8); PARTICIPATES IN creatine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA589632; Creat; creatine transporter 1; creatine transporter SLC6A8 variant D; creatine transporter, solute carrier family 6, member 8; CRT; CRTR; CT1; CTR5; sodium- and chloride-dependent creatine transporter 1; solute carrier family 6 member 8; solute carrier family 6, member 8
Homo sapiens (human) : SLC6A8 (solute carrier family 6 member 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc6a8 (solute carrier family 6 member 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc6a8 (solute carrier family 6 member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100975352 (sodium- and chloride-dependent creatine transporter 1)
Canis lupus familiaris (dog) : SLC6A8 (solute carrier family 6 member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc6a8 (solute carrier family 6 member 8)
Sus scrofa (pig) : SLC6A8 (solute carrier family 6 member 8)
Chlorocebus sabaeus (African green monkey) : SLC6A8 (solute carrier family 6 member 8)
Heterocephalus glaber (naked mole-rat) : Slc6a8 (solute carrier family 6 member 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 EnsemblX73,673,150 - 73,682,502 (+)EnsemblGRCm38mm10GRCm38
GRCm38X73,673,133 - 73,682,502 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X70,918,472 - 70,927,841 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X69,925,870 - 69,935,222 (+)NCBImm8
CeleraX64,926,949 - 64,936,317 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Slc6a8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733405
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.