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Gene: Slc6a8 (solute carrier family 6 (neurotransmitter transporter, creatine), member 8) Mus musculus
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Symbol: Slc6a8
Name: solute carrier family 6 (neurotransmitter transporter, creatine), member 8
Description: Predicted to have cation transmembrane transporter activity and neurotransmitter binding activity. Predicted to be involved in creatine transmembrane transport. Predicted to localize to glutamatergic synapse; integral component of postsynaptic membrane; and neuron projection. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study creatine transporter deficiency. Human ortholog(s) of this gene implicated in creatine transporter deficiency and intellectual disability. Orthologous to human SLC6A8 (solute carrier family 6 member 8); PARTICIPATES IN creatine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA589632; Creat; creatine transporter 1; creatine transporter SLC6A8 variant D; creatine transporter, solute carrier family 6, member 8; CRT; CRTR; CT1; CTR5; sodium- and chloride-dependent creatine transporter 1; solute carrier family 6 member 8; solute carrier family 6, member 8
Orthologs:
Homo sapiens (human) : SLC6A8 (solute carrier family 6 member 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc6a8 (solute carrier family 6 member 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc6a8 (solute carrier family 6 member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100975352 (sodium- and chloride-dependent creatine transporter 1)
Canis lupus familiaris (dog) : SLC6A8 (solute carrier family 6 member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc6a8 (solute carrier family 6 member 8)
Sus scrofa (pig) : SLC6A8 (solute carrier family 6 member 8)
Chlorocebus sabaeus (African green monkey) : SLC6A8 (solute carrier family 6 member 8)
Heterocephalus glaber (naked mole-rat) : Slc6a8 (solute carrier family 6 member 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 EnsemblX73,673,150 - 73,682,502 (+)EnsemblGRCm38mm10GRCm38
GRCm38X73,673,133 - 73,682,502 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X70,918,472 - 70,927,841 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X69,925,870 - 69,935,222 (+)NCBImm8
CeleraX64,926,949 - 64,936,317 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Slc6a8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733405
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.