Bop1 (block of proliferation 1) - Rat Genome Database

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Gene: Bop1 (block of proliferation 1) Mus musculus
Analyze
Symbol: Bop1
Name: block of proliferation 1
RGD ID: 1321586
MGI Page MGI
Description: Enables ribonucleoprotein complex binding activity. Involved in cell population proliferation and cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Acts upstream of or within rRNA processing and ribosomal large subunit biogenesis. Located in nucleolus. Is expressed in several structures, including central nervous system; female reproductive system; and urinary system. Orthologous to human BOP1 (BOP1 ribosomal biogenesis factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AU020183; AW146150; block of proliferation 1 protein; D18861; Erb; Erb1p; Kiaa0124; mKIAA0124; ribosome biogenesis protein BOP1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,337,188 - 76,361,449 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,337,189 - 76,361,477 (-)EnsemblGRCm39 Ensembl
GRCm381576,452,988 - 76,477,249 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,452,989 - 76,477,277 (-)EnsemblGRCm38mm10GRCm38
MGSCv371576,283,426 - 76,307,699 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361576,280,251 - 76,304,524 (-)NCBIMGSCv36mm8
Celera1577,953,429 - 77,977,780 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.91NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
chromium(6+)  (EXP)
clobetasol  (EXP)
cobalt dichloride  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
cylindrospermopsin  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
diquat  (EXP)
doxorubicin  (ISO)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (EXP)
flutamide  (ISO)
folic acid  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
glafenine  (ISO)
haloperidol  (ISO)
hydrogen peroxide  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
methidathion  (EXP)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
monosodium L-glutamate  (EXP)
N-ethyl-N-nitrosourea  (EXP)
nefazodone  (ISO)
nickel atom  (ISO)
nimesulide  (ISO)
paracetamol  (EXP)
paraquat  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sulfadimethoxine  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
tetrachloromethane  (ISO)
Theaflavin 3,3'-digallate  (ISO)
thioacetamide  (ISO)
topotecan  (ISO)
Triptolide  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. An overview of pre-ribosomal RNA processing in eukaryotes. Henras AK, etal., Wiley Interdiscip Rev RNA. 2015 Mar-Apr;6(2):225-42. doi: 10.1002/wrna.1269. Epub 2014 Oct 27.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Aug 31;10(4):167-80.
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing. Sloan KE, etal., J Cell Biol. 2013 Mar 4;200(5):577-88. doi: 10.1083/jcb.201207131. Epub 2013 Feb 25.
Additional References at PubMed
PMID:9829985   PMID:9872334   PMID:10349636   PMID:10891491   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11522832   PMID:11544199   PMID:12048210   PMID:12477932   PMID:12520002  
PMID:12904583   PMID:14610273   PMID:15225545   PMID:15489334   PMID:15782199   PMID:16043514   PMID:16141072   PMID:16141073   PMID:17353269   PMID:18287559   PMID:18809582   PMID:19996321  
PMID:21267068   PMID:21873635   PMID:22922362   PMID:22988430   PMID:24457600   PMID:25871848   PMID:26156959   PMID:28378742   PMID:30457570   PMID:30782837   PMID:31040226   PMID:32554809  
PMID:33510838   PMID:37615370   PMID:38409361  


Genomics

Comparative Map Data
Bop1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,337,188 - 76,361,449 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,337,189 - 76,361,477 (-)EnsemblGRCm39 Ensembl
GRCm381576,452,988 - 76,477,249 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,452,989 - 76,477,277 (-)EnsemblGRCm38mm10GRCm38
MGSCv371576,283,426 - 76,307,699 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361576,280,251 - 76,304,524 (-)NCBIMGSCv36mm8
Celera1577,953,429 - 77,977,780 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.91NCBI
BOP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388144,262,045 - 144,291,438 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8144,262,045 - 144,291,438 (-)EnsemblGRCh38hg38GRCh38
GRCh378145,316,948 - 145,331,185 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,456,864 - 145,485,928 (-)NCBINCBI36Build 36hg18NCBI36
Build 348145,456,863 - 145,485,928NCBI
Celera8141,660,871 - 141,689,893 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8140,600,632 - 140,629,634 (-)NCBIHuRef
CHM1_18145,538,487 - 145,553,302 (-)NCBICHM1_1
T2T-CHM13v2.08145,430,815 - 145,459,890 (-)NCBIT2T-CHM13v2.0
Bop1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,052,716 - 110,076,529 (-)NCBIGRCr8
mRatBN7.27108,172,062 - 108,195,875 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,172,066 - 108,195,931 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7109,916,459 - 109,940,262 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,140,156 - 112,163,959 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,098,544 - 112,122,309 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,514,529 - 117,538,342 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,514,533 - 117,538,342 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,502,160 - 117,525,973 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,500,155 - 114,524,030 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17114,534,386 - 114,558,260 (-)NCBI
Celera7104,523,713 - 104,547,502 (-)NCBICelera
Cytogenetic Map7q34NCBI
Bop1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554542,882,755 - 2,907,081 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554542,882,694 - 2,907,177 (-)NCBIChiLan1.0ChiLan1.0
BOP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,747,719 - 161,778,596 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18137,277,841 - 137,308,511 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08141,024,518 - 141,055,173 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18144,015,518 - 144,043,278 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8144,015,601 - 144,043,280 (-)Ensemblpanpan1.1panPan2
BOP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,698,635 - 37,723,803 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,698,698 - 37,724,457 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,662,427 - 37,688,100 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01338,174,993 - 38,200,746 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1338,174,997 - 38,199,877 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,847,179 - 37,871,825 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,975,815 - 38,001,527 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,452,110 - 38,477,850 (-)NCBIUU_Cfam_GSD_1.0
Bop1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303524,835 - 551,088 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364707,950,982 - 7,977,540 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364707,950,952 - 7,977,186 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BOP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4475,426 - 507,138 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14486,562 - 507,141 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24681,204 - 684,059 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BOP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,473,377 - 138,503,715 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,473,441 - 138,503,661 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660391,360,979 - 1,392,558 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bop1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,562,997 - 12,585,971 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473512,562,734 - 12,586,544 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bop1
360 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:137
Count of miRNA genes:130
Interacting mature miRNAs:131
Transcripts:ENSMUST00000023217
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1357703Vtbt17_mvertebral trabecular bone trait 17 (mouse)Not determined154455331378553437Mouse
1301568Tria2_mT-cell receptor induced activation 2 (mouse)Not determined154485914178859281Mouse
1357756Alaa4_malopecia areata 4 (mouse)Not determined154638964680389845Mouse
10755515Amzn3_manatomical modifier of Zfp423 3 (mouse)154638964680389845Mouse
1301006Hfib1_mhepatic fibrogenesis 1 (mouse)Not determined154730633481306479Mouse
1301860Gct3_mgranulosa cell tumorigenesis 3 (mouse)Not determined154740959681409691Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
1301779Dpml_mdopamine loss (mouse)Not determined155100469476794493Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1558786Msq1_mMAV-1 susceptibility QTL 1 (mouse)Not determined156338964681086436Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1300844Emo2_memotionality 2 (mouse)Not determined157237245976794493Mouse
1302002Cocia2_mcocaine induced activation 2 (mouse)Not determined157237245979899178Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157410054082674156Mouse
13442492Mecth2_mmechanosensation threshold 2 (mouse)157466284979387201Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse

Markers in Region
RH136369  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381576,453,123 - 76,453,343UniSTSGRCm38
MGSCv371576,283,553 - 76,283,773UniSTSGRCm37
Celera1577,953,556 - 77,953,776UniSTS
Cytogenetic Map15D3UniSTS
cM Map1543.0UniSTS
AW146150  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381576,453,138 - 76,453,240UniSTSGRCm38
MGSCv371576,283,568 - 76,283,670UniSTSGRCm37
Celera1577,953,571 - 77,953,673UniSTS
Cytogenetic Map15D3UniSTS
cM Map1543.0UniSTS
Whitehead/MRC_RH15645.4UniSTS
Whitehead/MRC_RH15645.91UniSTS
UniSTS:237330  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381576,475,774 - 76,475,989UniSTSGRCm38
MGSCv371576,306,204 - 76,306,419UniSTSGRCm37
Celera1577,976,285 - 77,976,500UniSTS
Cytogenetic Map15D3UniSTS
cM Map1543.0UniSTS
cM Map1543.0UniSTS
AI169617  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381576,453,055 - 76,453,247UniSTSGRCm38
MGSCv371576,283,485 - 76,283,677UniSTSGRCm37
Celera1577,953,488 - 77,953,680UniSTS
Cytogenetic Map15D3UniSTS
cM Map1543.0UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS
Scx  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381576,458,158 - 76,459,208UniSTSGRCm38
MGSCv371576,288,588 - 76,289,638UniSTSGRCm37
Celera1577,958,589 - 77,959,639UniSTS
Cytogenetic Map15D3UniSTS
cM Map1543.3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_013481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC157566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF061503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK129058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV349722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U77415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000023217   ⟹   ENSMUSP00000023217
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,337,189 - 76,361,477 (-)Ensembl
GRCm38.p6 Ensembl1576,452,989 - 76,477,277 (-)Ensembl
RefSeq Acc Id: ENSMUST00000229132
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,339,693 - 76,340,473 (-)Ensembl
GRCm38.p6 Ensembl1576,455,493 - 76,456,273 (-)Ensembl
RefSeq Acc Id: ENSMUST00000229633
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,338,079 - 76,338,943 (-)Ensembl
GRCm38.p6 Ensembl1576,453,879 - 76,454,743 (-)Ensembl
RefSeq Acc Id: ENSMUST00000229897
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1576,339,416 - 76,340,228 (-)Ensembl
GRCm38.p6 Ensembl1576,455,216 - 76,456,028 (-)Ensembl
RefSeq Acc Id: NM_013481   ⟹   NP_038509
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391576,337,188 - 76,361,449 (-)NCBI
GRCm381576,452,988 - 76,477,249 (-)NCBI
MGSCv371576,283,426 - 76,307,699 (-)RGD
Celera1577,953,429 - 77,977,780 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036159096   ⟹   XP_036014989
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391576,337,188 - 76,346,549 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_038509   ⟸   NM_013481
- UniProtKB: Q6ZQI9 (UniProtKB/Swiss-Prot),   Q3TK87 (UniProtKB/Swiss-Prot),   Q91X31 (UniProtKB/Swiss-Prot),   P97452 (UniProtKB/Swiss-Prot),   Q3TJZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000023217   ⟸   ENSMUST00000023217
RefSeq Acc Id: XP_036014989   ⟸   XM_036159096
- Peptide Label: isoform X1
Protein Domains
BOP1 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97452-F1-model_v2 AlphaFold P97452 1-732 view protein structure

Promoters
RGD ID:6847174
Promoter ID:MM_ACW:18483
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney
Transcripts:BOP1.HSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361576,284,506 - 76,285,757 (-)MPROMDB
RGD ID:6825822
Promoter ID:MM_KWN:18875
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000023215,   ENSMUST00000100506,   NM_008296,   NM_013481,   UC007WKI.1,   UC007WKJ.1,   UC007WKK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361576,307,641 - 76,308,532 (-)MPROMDB
RGD ID:8684120
Promoter ID:EPDNEW_M20090
Type:initiation region
Name:Bop1_1
Description:Mus musculus block of proliferation 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381576,477,249 - 76,477,309EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1334460 AgrOrtholog
Ensembl Genes ENSMUSG00000022557 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000023217 ENTREZGENE
  ENSMUST00000023217.11 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BOP1/Erb1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BOP1_N_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12181 UniProtKB/Swiss-Prot
MGD MGI:1334460 ENTREZGENE
NCBI Gene 12181 ENTREZGENE
PANTHER PTHR17605 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIBOSOME BIOGENESIS PROTEIN BOP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BOP1NT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bop1 PhenoGen
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BOP1NT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt BOP1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3THV0_MOUSE UniProtKB/TrEMBL
  Q3TIJ5_MOUSE UniProtKB/TrEMBL
  Q3TJZ5 ENTREZGENE, UniProtKB/TrEMBL
  Q3TK87 ENTREZGENE
  Q6ZQI9 ENTREZGENE
  Q91X31 ENTREZGENE
UniProt Secondary Q3TK87 UniProtKB/Swiss-Prot
  Q6ZQI9 UniProtKB/Swiss-Prot
  Q91X31 UniProtKB/Swiss-Prot