Cryab (crystallin, alpha B) - Rat Genome Database
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Gene: Cryab (crystallin, alpha B) Mus musculus
Analyze
Symbol: Cryab
Name: crystallin, alpha B
RGD ID: 10400
MGI Page MGI
Description: Predicted to have several functions, including amyloid-beta binding activity; protein homodimerization activity; and unfolded protein binding activity. Involved in several processes, including lens development in camera-type eye; negative regulation of macromolecule metabolic process; and tubulin complex assembly. Localizes to several cellular components, including Z disc; cytosol; and mitochondrion. Is expressed in several structures, including brain; embryo mesenchyme; eye; heart; and musculature. Used to study cataract 16 multiple types and myofibrillar myopathy 2. Human ortholog(s) of this gene implicated in cataract 16 multiple types; dilated cardiomyopathy 1II; fatal infantile hypertonic myofibrillar myopathy; and myofibrillar myopathy 2. Orthologous to human CRYAB (crystallin alpha B).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha B-crystallin; alpha(B)-crystallin; alpha-crystallin B chain; Cry; Crya; Crya-2; Crya2; crystallin, alpha 2; heat shock protein CryAB; heat shock protein HspB5; Hsp; HspB5; P23
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39950,657,251 - 50,667,936 (+)NCBIGRCm39mm39
GRCm39 Ensembl950,662,625 - 50,667,936 (+)Ensembl
GRCm38950,745,951 - 50,756,636 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl950,751,325 - 50,756,636 (+)EnsemblGRCm38mm10GRCm38
MGSCv37950,560,863 - 50,564,738 (+)NCBIGRCm37mm9NCBIm37
MGSCv36950,504,988 - 50,508,863 (+)NCBImm8
Celera948,039,922 - 48,043,797 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map927.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (ISO)
1-nitropropane  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
1H-pyrazole  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-diaminotoluene  (ISO)
2,6-diaminotoluene  (ISO)
2,6-dichloroindophenol  (ISO)
2,6-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-nitro-p-phenylenediamine  (ISO)
2-nitrofluorene  (ISO)
2-nitropropane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-acetylaminofluorene  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-nitro-1,2-phenylenediamine  (ISO)
4-nitroquinoline N-oxide  (EXP)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
7H-xanthine  (ISO)
9H-xanthine  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
amphibole asbestos  (ISO)
arecoline  (EXP)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (ISO)
Aurin  (ISO)
azetidinecarboxylic acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bortezomib  (ISO)
bucladesine  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
captan  (EXP)
casticin  (EXP)
celastrol  (ISO)
celecoxib  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
cisplatin  (EXP,ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
crocidolite asbestos  (EXP,ISO)
CU-O LINKAGE  (ISO)
curcumin  (EXP,ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dihydroxyacetone  (ISO)
Diisodecyl phthalate  (EXP)
dimethylarsinous acid  (ISO)
disulfiram  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elesclomol  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
formaldehyde  (ISO)
furan  (ISO)
gentamycin  (ISO)
glutathione  (ISO)
Hexachloro-1,3-butadiene  (ISO)
indole-3-methanol  (ISO)
indometacin  (ISO)
iopamidol  (ISO)
isoprenaline  (ISO)
ketamine  (ISO)
L-ascorbic acid  (ISO)
lead diacetate  (EXP)
lead nitrate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lipopolysaccharide  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
manganese(II) chloride  (ISO)
masoprocol  (ISO)
melittin  (ISO)
mercury atom  (EXP)
mercury(0)  (EXP)
methamphetamine  (ISO)
methanol  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
mifepristone  (ISO)
morphine  (EXP,ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nickel dichloride  (ISO)
nicotine  (EXP)
ochratoxin A  (ISO)
orphenadrine  (ISO)
ozone  (ISO)
paracetamol  (ISO)
PCB138  (EXP)
PhIP  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
prostaglandin A1  (ISO)
prostaglandin A2  (ISO)
prostaglandin D2  (ISO)
prostaglandin E2  (ISO)
prostaglandin J2  (ISO)
resveratrol  (EXP)
SB 431542  (ISO)
SCH 23390  (ISO)
scopolamine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium nitrate  (EXP)
sodium tungstate  (ISO)
Soman  (ISO)
sulforaphane  (ISO)
sulindac sulfide  (ISO)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetracycline  (EXP)
thimerosal  (ISO)
thioacetamide  (ISO)
thiostrepton  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (EXP)
troglitazone  (ISO)
ursodeoxycholic acid  (ISO)
usnic acid  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc pyrithione  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1846673   PMID:1875925   PMID:2539261   PMID:2725488   PMID:3862098   PMID:7838723   PMID:8072529   PMID:8165144   PMID:8293998   PMID:8413303   PMID:8524275   PMID:8552401  
PMID:8672141   PMID:8798491   PMID:8827514   PMID:8843924   PMID:8875078   PMID:8889548   PMID:8961256   PMID:8989522   PMID:9023351   PMID:9512512   PMID:9813033   PMID:9880236  
PMID:10080188   PMID:10349636   PMID:10383433   PMID:10603348   PMID:10751411   PMID:10890982   PMID:11042159   PMID:11076861   PMID:11149910   PMID:11156955   PMID:11157875   PMID:11217851  
PMID:11245977   PMID:11304494   PMID:11687538   PMID:11714668   PMID:12403771   PMID:12426373   PMID:12446761   PMID:12477932   PMID:12529319   PMID:12546709   PMID:12826669   PMID:14523008  
PMID:14556987   PMID:14576194   PMID:14592939   PMID:14610273   PMID:14627610   PMID:15102471   PMID:15113840   PMID:15188402   PMID:15220483   PMID:15483628   PMID:15489334   PMID:15543941  
PMID:15593327   PMID:15609325   PMID:15820311   PMID:15907784   PMID:16141072   PMID:16141073   PMID:16155124   PMID:16162653   PMID:16199865   PMID:16210548   PMID:16217658   PMID:16316967  
PMID:16439475   PMID:16446698   PMID:16602821   PMID:16618939   PMID:16675842   PMID:16678848   PMID:16979163   PMID:17081987   PMID:17222797   PMID:17293452   PMID:17389375   PMID:17438522  
PMID:17568699   PMID:17634366   PMID:17661394   PMID:17846079   PMID:17873008   PMID:17893660   PMID:17939115   PMID:17993600   PMID:18056999   PMID:18063749   PMID:18191123   PMID:18227158  
PMID:18384969   PMID:18621691   PMID:18652817   PMID:18675797   PMID:18757513   PMID:18974385   PMID:19129171   PMID:19252088   PMID:19334279   PMID:19409883   PMID:19423573   PMID:19538478  
PMID:19570848   PMID:19623612   PMID:19624757   PMID:19767775   PMID:19794138   PMID:19799774   PMID:20005263   PMID:20023214   PMID:20027618   PMID:20067574   PMID:20441791   PMID:20484573  
PMID:20523125   PMID:20735985   PMID:20937869   PMID:20959464   PMID:21162300   PMID:21185283   PMID:21267068   PMID:21305474   PMID:21379584   PMID:21423662   PMID:21445271   PMID:21494593  
PMID:21541347   PMID:21565611   PMID:21600198   PMID:21640763   PMID:21768101   PMID:21828004   PMID:21998302   PMID:22179185   PMID:22240097   PMID:22280356   PMID:22289178   PMID:22308023  
PMID:22442691   PMID:22781655   PMID:22904156   PMID:22937058   PMID:23033322   PMID:23242137   PMID:23395094   PMID:23471649   PMID:23482492   PMID:23542032   PMID:23579188   PMID:23590631  
PMID:23872361   PMID:23929007   PMID:24038357   PMID:24077282   PMID:24154525   PMID:24307592   PMID:24859470   PMID:24874187   PMID:24951838   PMID:25347445   PMID:26066304   PMID:26071686  
PMID:26251235   PMID:26542570   PMID:26718604   PMID:26878210   PMID:26987815   PMID:27388634   PMID:27566162   PMID:27724964   PMID:27824296   PMID:27918583   PMID:28185662   PMID:28237965  
PMID:28378742   PMID:28489004   PMID:29135941   PMID:29164525   PMID:29338044   PMID:29459677   PMID:29866044   PMID:30342008   PMID:30389787   PMID:30497777   PMID:30683901   PMID:30773991  
PMID:31226261   PMID:31369034   PMID:31481750   PMID:32325033   PMID:32554860   PMID:32616056   PMID:32833997   PMID:32913205  


Genomics

Comparative Map Data
Cryab
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39950,657,251 - 50,667,936 (+)NCBIGRCm39mm39
GRCm39 Ensembl950,662,625 - 50,667,936 (+)Ensembl
GRCm38950,745,951 - 50,756,636 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl950,751,325 - 50,756,636 (+)EnsemblGRCm38mm10GRCm38
MGSCv37950,560,863 - 50,564,738 (+)NCBIGRCm37mm9NCBIm37
MGSCv36950,504,988 - 50,508,863 (+)NCBImm8
Celera948,039,922 - 48,043,797 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map927.75NCBI
CRYAB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11111,908,564 - 111,923,722 (-)EnsemblGRCh38hg38GRCh38
GRCh3811111,908,564 - 111,923,740 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711111,779,288 - 111,794,464 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611111,284,560 - 111,287,683 (-)NCBINCBI36hg18NCBI36
Build 3411111,284,559 - 111,287,683NCBI
Celera11108,932,558 - 108,935,681 (-)NCBI
Cytogenetic Map11q23.1NCBI
HuRef11107,703,256 - 107,706,379 (-)NCBIHuRef
CHM1_111111,662,424 - 111,667,017 (-)NCBICHM1_1
Cryab
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2851,093,441 - 51,099,161 (+)NCBI
Rnor_6.0 Ensembl855,178,289 - 55,182,545 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0855,178,543 - 55,182,546 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0853,776,100 - 53,779,780 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4854,107,824 - 54,111,502 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1854,126,302 - 54,130,559 (+)NCBI
Celera850,642,744 - 50,646,745 (+)NCBICelera
Cytogenetic Map8q23NCBI
Cryab
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541213,625,363 - 13,640,426 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541213,626,018 - 13,629,495 (-)NCBIChiLan1.0ChiLan1.0
CRYAB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111110,639,442 - 110,644,245 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11110,639,442 - 110,644,272 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011106,795,406 - 106,800,019 (-)NCBIMhudiblu_PPA_v0panPan3
CRYAB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1521,181,836 - 21,185,164 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl521,179,936 - 21,360,132 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha521,104,096 - 21,107,406 (+)NCBI
ROS_Cfam_1.0521,204,772 - 21,208,082 (+)NCBI
UMICH_Zoey_3.1521,266,069 - 21,269,377 (+)NCBI
UNSW_CanFamBas_1.0521,166,521 - 21,169,831 (+)NCBI
UU_Cfam_GSD_1.0521,215,316 - 21,218,626 (+)NCBI
Cryab
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494794,169,136 - 94,173,881 (-)NCBI
SpeTri2.0NW_0049366122,532,851 - 2,536,473 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRYAB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl939,638,502 - 39,643,530 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1939,638,505 - 39,643,530 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2944,428,979 - 44,433,758 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRYAB
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11103,258,715 - 103,263,274 (-)NCBI
ChlSab1.1 Ensembl1103,257,347 - 103,261,990 (-)Ensembl
Vero_WHO_p1.0NW_02366604322,707,897 - 22,722,116 (+)NCBI
Cryab
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247847,074,590 - 7,093,471 (-)NCBI

Position Markers
D19440  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A5.3UniSTS
Whitehead_YAC9 UniSTS
D9Mit96  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38950,753,738 - 50,753,928UniSTSGRCm38
MGSCv37950,561,843 - 50,562,033UniSTSGRCm37
Celera948,040,902 - 48,041,092UniSTS
Cytogenetic Map9A5.3UniSTS
cM Map929.0UniSTS
Whitehead Genetic924.0UniSTS
Cryab  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A5.3UniSTS
cM Map929.0UniSTS
RH143847  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38950,751,272 - 50,751,411UniSTSGRCm38
MGSCv37950,559,377 - 50,559,516UniSTSGRCm37
Celera948,038,438 - 48,038,577UniSTS
Cytogenetic Map9A5.3UniSTS
PMC123035P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38950,752,382 - 50,753,307UniSTSGRCm38
MGSCv37950,560,487 - 50,561,412UniSTSGRCm37
Celera948,039,547 - 48,040,471UniSTS
Cytogenetic Map9A5.3UniSTS
Cryab  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A5.3UniSTS
cM Map929.0UniSTS
Cryab  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A5.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13504834Hdlq109_mHDL QTL 109 (mouse)91679834550798345Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91706754451067647Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined92003211054032229Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92024206654242196Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92039490154395074Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92039490154395074Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92039490154395074Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92039490154395074Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92094144454941444Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92500000069000000Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92567618959676285Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92567618959676285Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92567618959676285Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92567618959676285Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92688512460885255Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92688512460885255Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92688512460885255Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92733989761340026Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92938163163381774Mouse
1301782Chol11_mcholesterol 11 (mouse)Not determined92938163163381774Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93014186664141979Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93082861764828723Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93252326366523557Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93254112166541246Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93259987266600121Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93297840266978536Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93319972567199840Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93406754473531973Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93512317869123299Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93512317869123299Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93512317869123299Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93739490198819654Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93791224471912244Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93819229172192291Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93819229172192291Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93819229172192291Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93949260173492601Mouse
1558993Tdmq1_mtype 2 diabetes modifying QTL 1 (mouse)Not determined94050829851897370Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94050829874700643Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94089776474897921Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94357343177573577Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94357343177573577Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94452089278520980Mouse
4141572Ntta3_mneurotensin transcript abundance 3 (mouse)Not determined4668637365923895Mouse
4141754Fecq4_mfecundity QTL 4 (mouse)Not determined94763172657897921Mouse
13515057Adip20b_madiposity 20b (mouse)94878960853884418Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94892377482923895Mouse
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94892377482923895Mouse
1301051Eae9_msusceptibility to experimental allergic encephalomyelitis 9 (mouse)Not determined94950899863332570Mouse
1301049El4_mepilepsy 4 (mouse)Not determined94950899867244166Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49541121101528921Mouse
14746993Manh66_mmandible shape 66 (mouse)94990676683906766Mouse
11080993Tglq7_mtriglyceride level QTL 7 (mouse)95020000051600000Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95024403884244166Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:95
Interacting mature miRNAs:101
Transcripts:ENSMUST00000034562
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001289782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030244036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036154592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC113987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M25770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M63170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M73741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000034562   ⟹   ENSMUSP00000034562
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl950,752,907 - 50,756,543 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214609   ⟹   ENSMUSP00000149454
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl950,751,877 - 50,756,359 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214962   ⟹   ENSMUSP00000149759
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl950,752,993 - 50,756,630 (+)Ensembl
RefSeq Acc Id: ENSMUST00000216393
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl950,754,395 - 50,756,636 (+)Ensembl
RefSeq Acc Id: ENSMUST00000216755   ⟹   ENSMUSP00000150669
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl950,753,020 - 50,756,636 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217475   ⟹   ENSMUSP00000149803
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl950,751,325 - 50,756,636 (+)Ensembl
RefSeq Acc Id: NM_001289782   ⟹   NP_001276711
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39950,662,625 - 50,667,936 (+)NCBI
GRCm38950,751,325 - 50,756,636 (+)NCBI
Celera948,038,491 - 48,043,798 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001289784   ⟹   NP_001276713
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39950,664,271 - 50,667,936 (+)NCBI
GRCm38950,752,971 - 50,756,636 (+)NCBI
Celera948,038,491 - 48,043,798 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001289785   ⟹   NP_001276714
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39950,664,271 - 50,667,936 (+)NCBI
GRCm38950,752,971 - 50,756,636 (+)NCBI
Celera948,038,491 - 48,043,798 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009964   ⟹   NP_034094
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39950,664,271 - 50,667,936 (+)NCBI
GRCm38950,752,971 - 50,756,636 (+)NCBI
MGSCv37950,560,863 - 50,564,738 (+)RGD
Celera948,038,491 - 48,043,798 (+)NCBI
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030244036   ⟹   XP_030099896
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39950,657,251 - 50,667,936 (+)NCBI
GRCm38950,745,951 - 50,756,636 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036154592   ⟹   XP_036010485
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39950,664,196 - 50,667,936 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_034094   ⟸   NM_009964
- UniProtKB: P23927 (UniProtKB/Swiss-Prot),   Q52L78 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276711   ⟸   NM_001289782
- UniProtKB: P23927 (UniProtKB/Swiss-Prot),   Q52L78 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276713   ⟸   NM_001289784
- UniProtKB: P23927 (UniProtKB/Swiss-Prot),   Q52L78 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276714   ⟸   NM_001289785
- UniProtKB: P23927 (UniProtKB/Swiss-Prot),   Q52L78 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030099896   ⟸   XM_030244036
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000149803   ⟸   ENSMUST00000217475
RefSeq Acc Id: ENSMUSP00000150669   ⟸   ENSMUST00000216755
RefSeq Acc Id: ENSMUSP00000034562   ⟸   ENSMUST00000034562
RefSeq Acc Id: ENSMUSP00000149454   ⟸   ENSMUST00000214609
RefSeq Acc Id: ENSMUSP00000149759   ⟸   ENSMUST00000214962
RefSeq Acc Id: XP_036010485   ⟸   XM_036154592
- Peptide Label: isoform X1
Protein Domains
sHSP

Promoters
RGD ID:6844673
Promoter ID:MM_KWN:57313
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000034562,   ENSMUST00000093849,   NM_001164708,   NM_009964,   NM_024441,   UC009PKN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36950,560,206 - 50,562,087 (-)MPROMDB
RGD ID:8669570
Promoter ID:EPDNEW_M12815
Type:initiation region
Name:Cryab_1
Description:Mus musculus crystallin, alpha B , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M12816  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38950,752,971 - 50,753,031EPDNEW
RGD ID:8669572
Promoter ID:EPDNEW_M12816
Type:initiation region
Name:Cryab_2
Description:Mus musculus crystallin, alpha B , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M12815  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38950,753,234 - 50,753,294EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88516 AgrOrtholog
Ensembl Genes ENSMUSG00000032060 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000034562 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000149454 UniProtKB/TrEMBL
  ENSMUSP00000149759 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000149803 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000150669 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000034562 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000214609 UniProtKB/TrEMBL
  ENSMUST00000214962 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000216755 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000217475 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.790 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro A-crystallin/Hsp20_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ACD_alphaB-crystallin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Alpha-crystallin/HSP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Alpha-crystallin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP20-like_chaperone UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12955 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:88516 ENTREZGENE
NCBI Gene 12955 ENTREZGENE
PANTHER PTHR45640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Crystallin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cryab PhenoGen
PIRSF Sm_HSP_B1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS ACRYSTALLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SHSP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49764 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1L1SRG5_MOUSE UniProtKB/TrEMBL
  CRYAB_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q52L78 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q64325 UniProtKB/Swiss-Prot