Rac1 (Rac family small GTPase 1) - Rat Genome Database
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Gene: Rac1 (Rac family small GTPase 1) Mus musculus
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Symbol: Rac1
Name: Rac family small GTPase 1
RGD ID: 1553531
MGI Page MGI
Description: Exhibits GTP binding activity; GTP-dependent protein binding activity; and GTPase activity. Involved in several processes, including cell morphogenesis involved in differentiation; generation of neurons; and plasma membrane bounded cell projection assembly. Localizes to several cellular components, including kinocilium; pericentriolar material; and ruffle membrane. Predicted to colocalize with actin filament. Is expressed in several structures, including brain; early conceptus; eye; pelvic urethra; and reproductive system. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 48; colon adenocarcinoma; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; Arf family mediated signaling pathway; azathioprine pharmacodynamics pathway; INTERACTS WITH 1,2-dimethylhydrazine; 1,8-cineole; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AL023026; D5Ertd559; D5Ertd559e; p21-Rac1; RAS-related C3 botulinum substrate 1; ras-related C3 botulinum toxin substrate 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395143,491,236 - 143,513,786 (-)NCBIGRCm39mm39
GRCm385143,505,481 - 143,528,031 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5143,503,634 - 143,528,036 (-)EnsemblGRCm38mm10GRCm38
MGSCv375144,266,349 - 144,288,861 (-)NCBIGRCm37mm9NCBIm37
MGSCv365143,761,100 - 143,783,611 (-)NCBImm8
Celera5140,552,192 - 140,574,740 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map582.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(R)-mevalonic acid  (ISO)
1,2-dimethylhydrazine  (EXP)
1,8-cineole  (EXP)
11-deoxycorticosterone  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
2-trans,6-trans-farnesyl diphosphate  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-methylcholanthrene  (EXP)
3-phenylprop-2-enal  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxycoumarin  (EXP)
4-tert-Octylphenol  (ISO)
acetylsalicylic acid  (ISO)
aflatoxin B2  (ISO)
AICA ribonucleotide  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
atorvastatin calcium  (EXP,ISO)
azathioprine  (ISO)
azithromycin  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (ISO)
C60 fullerene  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (ISO)
captan  (EXP)
carbon nanotube  (EXP)
carvedilol  (ISO)
chloropicrin  (ISO)
chloroprene  (ISO)
cholesterol  (EXP,ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
D-glucose  (EXP,ISO)
daidzein  (EXP)
Deguelin  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (EXP,ISO)
dibenziodolium  (EXP)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
farnesyl diphosphate  (ISO)
felodipine  (EXP)
flavonoids  (ISO)
flubendazole  (ISO)
folic acid  (EXP)
folpet  (EXP)
gallic acid  (ISO)
genistein  (EXP)
gentamycin  (ISO)
geranylgeraniol  (ISO)
glucose  (EXP,ISO)
graphene oxide  (EXP)
GTP  (EXP,ISO)
guanosine 5'-[gamma-thio]triphosphate  (ISO)
haloperidol  (ISO)
heparin  (ISO)
irbesartan  (EXP)
kainic acid  (ISO)
kanamycin A  (EXP)
L-ascorbic acid  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (EXP,ISO)
lovastatin  (ISO)
mebendazole  (ISO)
melittin  (ISO)
mercury atom  (ISO)
mercury dichloride  (ISO)
mercury(0)  (ISO)
methohexital  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
mevastatin  (EXP)
ML-7  (ISO)
mycophenolic acid  (ISO)
N-acetyl-L-cysteine  (ISO)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (EXP)
N-nitrosodiethylamine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nebivolol  (ISO)
nitrofen  (ISO)
NSC 23766  (EXP,ISO)
oxaliplatin  (ISO)
p-tert-Amylphenol  (ISO)
paclitaxel  (ISO)
PD 0325901  (ISO)
pentobarbital  (ISO)
phenylephrine  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
plitidepsin  (ISO)
poly(I:C)  (ISO)
potassium chromate  (ISO)
pyrrolidine dithiocarbamate  (ISO)
ranitidine  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
Risedronate sodium  (EXP,ISO)
rotenone  (ISO)
secobarbital  (ISO)
serpentine asbestos  (EXP,ISO)
simvastatin  (EXP,ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (EXP,ISO)
sodium dichromate  (ISO)
spironolactone  (ISO)
streptozocin  (EXP,ISO)
styrene oxide  (EXP)
sucrose  (EXP)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tetrachloromethane  (EXP)
thiamylal  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
trimethyltin  (EXP)
Triptolide  (ISO)
uranium atom  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP)
vinclozolin  (ISO)
Y-27632  (ISO)
zinc dichloride  (EXP)
zinc oxide  (ISO)
zoledronic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (ISO)
actin filament organization  (IBA,ISO)
actin filament polymerization  (IDA)
anatomical structure arrangement  (IMP)
auditory receptor cell morphogenesis  (IMP)
axon guidance  (IMP)
bone resorption  (ISO)
cell adhesion  (IDA)
cell migration  (IDA)
cell motility  (ISO)
cell population proliferation  (ISO)
cell projection assembly  (IBA)
cell-cell junction organization  (IMP)
cellular response to mechanical stimulus  (ISO)
cerebral cortex GABAergic interneuron development  (IGI)
cerebral cortex radially oriented cell migration  (IMP)
chemotaxis  (ISO)
cochlea morphogenesis  (IMP)
cortical cytoskeleton organization  (IBA)
cytoskeleton organization  (IDA)
dendrite development  (IDA)
dendrite morphogenesis  (IGI)
dopaminergic neuron differentiation  (IGI)
embryonic olfactory bulb interneuron precursor migration  (IMP)
endocytosis  (IDA)
engulfment of apoptotic cell  (IBA,IDA)
epithelial cell morphogenesis  (IMP)
establishment or maintenance of cell polarity  (IBA)
forebrain development  (IDA)
G protein-coupled receptor signaling pathway  (IGI)
hepatocyte growth factor receptor signaling pathway  (ISO)
homeostasis of number of cells within a tissue  (IGI)
hyperosmotic response  (IDA)
lamellipodium assembly  (IDA,ISO,TAS)
localization within membrane  (ISO)
mast cell chemotaxis  (ISO)
midbrain dopaminergic neuron differentiation  (IMP)
motor neuron axon guidance  (IBA)
negative regulation of fibroblast migration  (ISO)
negative regulation of interleukin-23 production  (ISO)
neuron migration  (IMP)
neuron projection morphogenesis  (IGI)
non-canonical Wnt signaling pathway  (IGI)
phagocytosis, engulfment  (IMP)
positive regulation of actin filament polymerization  (IDA)
positive regulation of cell-substrate adhesion  (ISO)
positive regulation of dendritic spine development  (IGI,IMP)
positive regulation of DNA replication  (ISO)
positive regulation of endothelial cell migration  (ISO)
positive regulation of focal adhesion assembly  (ISO)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (IMP,ISO)
positive regulation of lamellipodium assembly  (ISO)
positive regulation of microtubule polymerization  (ISO)
positive regulation of neutrophil chemotaxis  (IMP,ISO)
positive regulation of ovarian follicle development  (IMP)
positive regulation of phosphatidylinositol 3-kinase activity  (IMP)
positive regulation of protein phosphorylation  (ISO)
positive regulation of stress fiber assembly  (ISO)
positive regulation of substrate adhesion-dependent cell spreading  (ISO)
protein localization to plasma membrane  (IDA)
Rac protein signal transduction  (IBA,ISO)
regulation of actin cytoskeleton organization  (IBA)
regulation of cell adhesion involved in heart morphogenesis  (IMP)
regulation of cell migration  (IMP,ISO)
regulation of cell morphogenesis  (IGI)
regulation of cell shape  (IBA)
regulation of cell size  (ISO)
regulation of fibroblast migration  (IMP)
regulation of lamellipodium assembly  (ISO)
regulation of neuron maturation  (IGI)
regulation of neuronal synaptic plasticity  (IGI,IMP)
regulation of neutrophil migration  (IBA)
regulation of nitric oxide biosynthetic process  (ISO)
regulation of receptor signaling pathway via JAK-STAT  (IMP)
regulation of respiratory burst  (ISO)
regulation of stress fiber assembly  (ISO)
ruffle assembly  (IMP,ISO)
ruffle organization  (ISO)
semaphorin-plexin signaling pathway  (ISO)
small GTPase mediated signal transduction  (IDA)
sphingosine-1-phosphate receptor signaling pathway  (ISO)
substrate adhesion-dependent cell spreading  (IDA,IMP,ISO)
synaptic transmission, GABAergic  (IGI)
Wnt signaling pathway, planar cell polarity pathway  (IGI)

Molecular Pathway Annotations     Click to see Annotation Detail View
amyotrophic lateral sclerosis pathway  (IEA)
Arf family mediated signaling pathway  (ISO)
azathioprine pharmacodynamics pathway  (ISO)
B cell receptor signaling pathway  (IEA)
c-Jun N-terminal kinases MAPK signaling pathway  (ISO)
ceramide signaling pathway  (IEA)
colorectal cancer pathway  (IEA)
E-cadherin signaling pathway  (ISO)
eicosanoid signaling pathway  (ISO)
endothelin signaling pathway  (ISO)
ephrin - ephrin receptor bidirectional signaling axis  (ISO)
Fc epsilon receptor mediated signaling pathway  (ISO)
insulin responsive facilitative sugar transporter mediated glucose transport pathway  (ISO)
interleukin-6 signaling pathway  (ISO)
mercaptopurine pharmacodynamics pathway  (ISO)
mercaptopurine pharmacokinetics pathway  (ISO)
mitogen activated protein kinase signaling pathway  (IEA)
mTOR signaling pathway  (ISO)
myocarditis pathway  (IEA)
N-cadherin signaling pathway  (ISO)
neurotrophic factor signaling pathway  (IEA)
p38 MAPK signaling pathway  (ISO)
pancreatic cancer pathway  (IEA)
phosphatidylinositol 3-kinase class I signaling pathway  (ISO)
platelet-derived growth factor signaling pathway  (ISO)
renal cell carcinoma pathway  (IEA)
Rho/Rac/Cdc42 mediated signaling pathway  (ISO)
sphingosine 1-phosphate signaling pathway  (ISO)
syndecan signaling pathway  (ISO)
tioguanine pharmacodynamics pathway  (ISO)
Toll-like receptor signaling pathway  (IEA)
vascular endothelial growth factor signaling pathway  (IEA)
Wnt signaling pathway  (IEA)
Wnt signaling, non-canonical pathway  (ISO)
Wnt signaling, the planar cell polarity pathway  (IMP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anterior visceral endoderm cell migration  (IAGP)
abnormal apoptosis  (IAGP)
abnormal barrel cortex morphology  (IAGP)
abnormal brain commissure morphology  (IAGP)
abnormal cell adhesion  (IAGP)
abnormal coat/ hair morphology  (IAGP)
abnormal corpus callosum morphology  (IAGP)
abnormal craniofacial development  (IAGP)
abnormal dentate gyrus morphology  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal embryo development  (IAGP)
abnormal embryonic epiblast morphology  (IAGP)
abnormal embryonic-extraembryonic boundary morphology  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal epidermis stratum basale morphology  (IAGP)
abnormal extraembryonic endoderm formation  (IAGP)
abnormal eye morphology  (IEA)
abnormal forelimb morphology  (IAGP)
abnormal gastrulation  (IAGP)
abnormal germ layer development  (IAGP)
abnormal hair cycle  (IAGP)
abnormal hair follicle bulge morphology  (IAGP)
abnormal hair follicle infundibulum morphology  (IAGP)
abnormal hair follicle morphology  (IAGP)
abnormal hair shaft morphology  (IAGP)
abnormal heart weight  (IEA)
abnormal hippocampus pyramidal cell layer  (IAGP)
abnormal keratinocyte physiology  (IAGP)
abnormal lymph node morphology  (IEA)
abnormal mesoderm development  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal neural tube closure  (IAGP)
abnormal notochordal plate morphology  (IAGP)
abnormal platelet activation  (IAGP)
abnormal primitive node morphology  (IAGP)
abnormal primitive streak formation  (IAGP)
abnormal primitive streak morphology  (IAGP)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal rostral-caudal body axis extension  (IAGP)
abnormal sebocyte number  (IAGP)
abnormal skin cell number  (IAGP)
abnormal skin condition  (IAGP)
abnormal skin physiology  (IAGP)
abnormal skin pigmentation  (IAGP)
abnormal spleen morphology  (IEA)
abnormal telencephalon morphology  (IAGP)
absent hair follicle bulb  (IAGP)
absent hindlimb  (IAGP)
absent mesoderm  (IAGP)
absent somites  (IAGP)
alopecia  (IAGP)
arrested B cell differentiation  (IAGP)
cardia bifida  (IAGP)
cardiac hypertrophy  (IAGP)
decreased acute inflammation  (IAGP)
decreased anterior commissure size  (IAGP)
decreased B cell number  (IAGP)
decreased B-1 B cell number  (IAGP)
decreased cell proliferation  (IAGP)
decreased embryo size  (IAGP)
decreased follicular B cell number  (IAGP)
decreased hippocampal commissure size  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased marginal zone B cell number  (IAGP)
decreased neutrophil cell number  (IAGP)
decreased platelet aggregation  (IAGP)
decreased survivor rate  (IAGP)
decreased transitional stage B cell number  (IAGP)
embryonic growth arrest  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
embryonic lethality between somite formation and embryo turning, complete penetrance  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
embryonic-extraembryonic boundary constriction  (IAGP)
enlarged lymph nodes  (IEA)
enlarged sebaceous gland  (IAGP)
enlarged spleen  (IEA)
exencephaly  (IAGP)
impaired neutrophil chemotaxis  (IAGP)
impaired neutrophil recruitment  (IAGP)
impaired somite development  (IAGP)
increased apoptosis  (IAGP)
increased embryonic tissue cell apoptosis  (IAGP)
increased left ventricle weight  (IAGP)
increased NAD(P)H oxidase activity  (IAGP)
microphthalmia  (IEA)
oxidative stress  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
small hippocampus  (IAGP)
spina bifida  (IAGP)
thick embryonic epiblast  (IAGP)
References

References - curated
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12. MGD data from the GO Consortium
13. MGD IEA
14. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
15. Pipeline to import KEGG annotations from KEGG into RGD
16. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
17. Pipeline to import SMPDB annotations from SMPDB into RGD
18. RGD automated import pipeline
19. RGD automated import pipeline for gene-chemical interactions
20. Rosso SB, etal., Nat Neurosci. 2005 Jan;8(1):34-42. Epub 2004 Dec 19.
21. Satoh M, etal., Proc Natl Acad Sci U S A. 2006 May 9;103(19):7432-7. Epub 2006 May 1.
22. Satoh T Small GTPases. 2014;5:e28102. doi: 10.4161/sgtp.28102. Epub 2014 Mar 10.
23. Takami Y, etal., Dig Dis Sci. 2008 Feb;53(2):467-73. Epub 2007 Jun 28.
24. Teramoto H, etal., J Biol Chem. 1996 Nov 1;271(44):27225-8.
25. Wang P, etal., Oncogene. 2014 Jan 23;33(4):514-24. doi: 10.1038/onc.2012.598. Epub 2013 Jan 21.
26. Wang Z, etal., Exp Mol Med. 2009 Oct 31;41(10):717-27. doi: 10.3858/emm.2009.41.10.078.
27. Wei L, etal., Development 2002 Apr;129(7):1705-14.
Additional References at PubMed
PMID:1905006   PMID:2550440   PMID:7561098   PMID:7671812   PMID:7888179   PMID:8464478   PMID:8543060   PMID:9395237   PMID:9438836   PMID:10030666   PMID:10349636   PMID:10464095  
PMID:10493740   PMID:10699171   PMID:10747961   PMID:10821761   PMID:10862698   PMID:10922068   PMID:10934045   PMID:10934474   PMID:10934475   PMID:10954424   PMID:11042159   PMID:11076861  
PMID:11108845   PMID:11130076   PMID:11562357   PMID:11713255   PMID:11728333   PMID:11747086   PMID:11790798   PMID:11884408   PMID:12213441   PMID:12213839   PMID:12351724   PMID:12376551  
PMID:12384416   PMID:12391220   PMID:12446704   PMID:12477932   PMID:12482591   PMID:12499359   PMID:12525493   PMID:12531901   PMID:12538863   PMID:12566226   PMID:12578823   PMID:12617831  
PMID:12759446   PMID:12783890   PMID:12805377   PMID:12810717   PMID:12829743   PMID:12853475   PMID:12857864   PMID:12861025   PMID:12874273   PMID:12912917   PMID:14506233   PMID:14516655  
PMID:14564009   PMID:14564011   PMID:14573547   PMID:14575316   PMID:14580336   PMID:14594451   PMID:14610273   PMID:14622142   PMID:14634666   PMID:14657280   PMID:14697354   PMID:14701795  
PMID:14718541   PMID:14764880   PMID:14966113   PMID:14996945   PMID:15033976   PMID:15054110   PMID:15060067   PMID:15085137   PMID:15102830   PMID:15151987   PMID:15234347   PMID:15249579  
PMID:15265981   PMID:15271660   PMID:15292195   PMID:15308574   PMID:15326354   PMID:15371457   PMID:15383465   PMID:15388231   PMID:15466361   PMID:15467718   PMID:15489334   PMID:15504745  
PMID:15528331   PMID:15557338   PMID:15579468   PMID:15647276   PMID:15652341   PMID:15673687   PMID:15703194   PMID:15728191   PMID:15728722   PMID:15761153   PMID:15775979   PMID:15782199  
PMID:15883643   PMID:15893749   PMID:15964829   PMID:16002401   PMID:16025125   PMID:16055737   PMID:16081735   PMID:16081809   PMID:16141072   PMID:16141073   PMID:16155095   PMID:16157315  
PMID:16170364   PMID:16174757   PMID:16186118   PMID:16195235   PMID:16195887   PMID:16294277   PMID:16328957   PMID:16362953   PMID:16368433   PMID:16440308   PMID:16455948   PMID:16462764  
PMID:16521128   PMID:16525021   PMID:16525721   PMID:16543941   PMID:16546099   PMID:16599904   PMID:16602821   PMID:16624865   PMID:16690620   PMID:16698790   PMID:16754961   PMID:16802292  
PMID:16809619   PMID:16814769   PMID:16863904   PMID:16882712   PMID:16917494   PMID:16943436   PMID:16990606   PMID:17012749   PMID:17021167   PMID:17041601   PMID:17041603   PMID:17056570  
PMID:17090688   PMID:17115888   PMID:17116687   PMID:17178910   PMID:17227220   PMID:17233629   PMID:17244648   PMID:17265067   PMID:17267693   PMID:17276347   PMID:17301832   PMID:17332503  
PMID:17334398   PMID:17389689   PMID:17409253   PMID:17409386   PMID:17428196   PMID:17467682   PMID:17500595   PMID:17562701   PMID:17573353   PMID:17576798   PMID:17576799   PMID:17653061  
PMID:17658519   PMID:17663742   PMID:17682062   PMID:17702745   PMID:17702746   PMID:17804720   PMID:17878342   PMID:17898204   PMID:17922611   PMID:17954607   PMID:17982024   PMID:17989211  
PMID:17991704   PMID:17996650   PMID:18003981   PMID:18045877   PMID:18059343   PMID:18060576   PMID:18067889   PMID:18070887   PMID:18083846   PMID:18089636   PMID:18089848   PMID:18156211  
PMID:18160398   PMID:18191593   PMID:18198193   PMID:18212043   PMID:18219391   PMID:18230340   PMID:18245172   PMID:18250451   PMID:18264091   PMID:18325335   PMID:18334560   PMID:18392843  
PMID:18403249   PMID:18422604   PMID:18423204   PMID:18424751   PMID:18502673   PMID:18505730   PMID:18505794   PMID:18576327   PMID:18579797   PMID:18583710   PMID:18591655   PMID:18599867  
PMID:18604197   PMID:18702697   PMID:18704487   PMID:18722484   PMID:18799693   PMID:18824165   PMID:18827016   PMID:18829452   PMID:18853424   PMID:18854161   PMID:18923147   PMID:18927084  
PMID:18940795   PMID:18953410   PMID:19007770   PMID:19029984   PMID:19088377   PMID:19095647   PMID:19118163   PMID:19118901   PMID:19122200   PMID:19126201   PMID:19126596   PMID:19147498  
PMID:19211846   PMID:19265663   PMID:19267423   PMID:19273601   PMID:19278959   PMID:19289122   PMID:19349358   PMID:19349584   PMID:19367791   PMID:19379695   PMID:19390057   PMID:19394428  
PMID:19404406   PMID:19429708   PMID:19443691   PMID:19450605   PMID:19455133   PMID:19463088   PMID:19470639   PMID:19581409   PMID:19585524   PMID:19589776   PMID:19592621   PMID:19620284  
PMID:19625648   PMID:19628969   PMID:19640983   PMID:19649754   PMID:19671682   PMID:19684199   PMID:19690049   PMID:19693013   PMID:19693014   PMID:19696411   PMID:19715691   PMID:19766620  
PMID:19820184   PMID:19850916   PMID:19852956   PMID:19858206   PMID:19861492   PMID:19893577   PMID:19906871   PMID:19940064   PMID:19955208   PMID:19955829   PMID:20004474   PMID:20016102  
PMID:20028975   PMID:20065081   PMID:20067919   PMID:20067994   PMID:20152175   PMID:20152179   PMID:20154721   PMID:20167866   PMID:20184871   PMID:20203090   PMID:20308364   PMID:20335173  
PMID:20335472   PMID:20339539   PMID:20346677   PMID:20383193   PMID:20418360   PMID:20457815   PMID:20463891   PMID:20484635   PMID:20493167   PMID:20506362   PMID:20518848   PMID:20522592  
PMID:20529870   PMID:20538003   PMID:20595387   PMID:20654717   PMID:20689803   PMID:20691665   PMID:20719958   PMID:20720104   PMID:20737513   PMID:20870900   PMID:20875796   PMID:20876660  
PMID:20883775   PMID:20974804   PMID:21071692   PMID:21148432   PMID:21177343   PMID:21178006   PMID:21206905   PMID:21212270   PMID:21289086   PMID:21357688   PMID:21358804   PMID:21406564  
PMID:21414312   PMID:21421844   PMID:21430700   PMID:21444756   PMID:21457935   PMID:21469092   PMID:21474067   PMID:21474673   PMID:21483795   PMID:21502320   PMID:21502507   PMID:21511011  
PMID:21533980   PMID:21542010   PMID:21559396   PMID:21590706   PMID:21618100   PMID:21645877   PMID:21663592   PMID:21677313   PMID:21684284   PMID:21690261   PMID:21693517   PMID:21712395  
PMID:21712438   PMID:21752934   PMID:21765214   PMID:21765460   PMID:21841162   PMID:21873454   PMID:21873635   PMID:21878794   PMID:21880919   PMID:21883766   PMID:21905163   PMID:21924960  
PMID:21940819   PMID:21945075   PMID:21946561   PMID:21949760   PMID:21966369   PMID:21976675   PMID:22021442   PMID:22023353   PMID:22037761   PMID:22043008   PMID:22056142   PMID:22075250  
PMID:22075471   PMID:22096246   PMID:22114304   PMID:22123845   PMID:22128191   PMID:22153076   PMID:22157745   PMID:22157762   PMID:22159416   PMID:22160594   PMID:22163037   PMID:22182523  
PMID:22198506   PMID:22243243   PMID:22275433   PMID:22276187   PMID:22345078   PMID:22384062   PMID:22393062   PMID:22450320   PMID:22453919   PMID:22461493   PMID:22461561   PMID:22498500  
PMID:22519702   PMID:22522400   PMID:22560610   PMID:22561898   PMID:22580124   PMID:22613570   PMID:22629471   PMID:22658956   PMID:22679019   PMID:22718121   PMID:22726444   PMID:22734669  
PMID:22750946   PMID:22767228   PMID:22773836   PMID:22790200   PMID:22932701   PMID:22936985   PMID:22956547   PMID:22956833   PMID:22959435   PMID:22970203   PMID:22995516   PMID:23027656  
PMID:23045281   PMID:23060091   PMID:23074275   PMID:23109420   PMID:23127797   PMID:23150167   PMID:23153508   PMID:23184573   PMID:23184663   PMID:23197717   PMID:23213469   PMID:23258346  
PMID:23263281   PMID:23274900   PMID:23288169   PMID:23296296   PMID:23325254   PMID:23392682   PMID:23412604   PMID:23416703   PMID:23423567   PMID:23429587   PMID:23453926   PMID:23462102  
PMID:23512198   PMID:23519127   PMID:23524265   PMID:23528453   PMID:23533177   PMID:23545410   PMID:23562267   PMID:23582786   PMID:23612479   PMID:23620790   PMID:23631848   PMID:23639811  
PMID:23640485   PMID:23657011   PMID:23665120   PMID:23665174   PMID:23677246   PMID:23706742   PMID:23719299   PMID:23720743   PMID:23733346   PMID:23734197   PMID:23759924   PMID:23771883  
PMID:23776598   PMID:23803609   PMID:23807227   PMID:23861250   PMID:23864022   PMID:23872330   PMID:23874203   PMID:23881099   PMID:23884931   PMID:23911822   PMID:23918979   PMID:23924974  
PMID:23950142   PMID:23951087   PMID:23967341   PMID:23978243   PMID:23989259   PMID:24045216   PMID:24061480   PMID:24091327   PMID:24144793   PMID:24188721   PMID:24216610   PMID:24244167  
PMID:24269593   PMID:24294595   PMID:24297853   PMID:24343664   PMID:24352656   PMID:24358134   PMID:24367707   PMID:24399839   PMID:24428713   PMID:24438685   PMID:24457600   PMID:24505282  
PMID:24508121   PMID:24559674   PMID:24586549   PMID:24598164   PMID:24603367   PMID:24626607   PMID:24628852   PMID:24651551   PMID:24706725   PMID:24706880   PMID:24817309   PMID:24877561  
PMID:24877974   PMID:24879442   PMID:24938713   PMID:24939893   PMID:24952961   PMID:24960694   PMID:25043299   PMID:25046439   PMID:25074804   PMID:25075639   PMID:25079357   PMID:25084221  
PMID:25118935   PMID:25128586   PMID:25139745   PMID:25164814   PMID:25209090   PMID:25211221   PMID:25253694   PMID:25288640   PMID:25295536   PMID:25311989   PMID:25315346   PMID:25358739  
PMID:25416549   PMID:25416624   PMID:25456130   PMID:25514037   PMID:25539497   PMID:25556150   PMID:25595128   PMID:25625545   PMID:25659584   PMID:25662279   PMID:25824687   PMID:25843690  
PMID:25864429   PMID:25865668   PMID:25896148   PMID:25917196   PMID:25925950   PMID:25991673   PMID:26002917   PMID:26075824   PMID:26184908   PMID:26198629   PMID:26202910   PMID:26205497  
PMID:26205662   PMID:26234352   PMID:26299339   PMID:26305333   PMID:26329303   PMID:26336360   PMID:26386179   PMID:26395878   PMID:26435502   PMID:26468229   PMID:26478565   PMID:26494286  
PMID:26496249   PMID:26496994   PMID:26558612   PMID:26582364   PMID:26585954   PMID:26679840   PMID:26722124   PMID:26726844   PMID:26728565   PMID:26747246   PMID:26859289   PMID:26872874  
PMID:26873877   PMID:26876204   PMID:26887924   PMID:26889750   PMID:26905694   PMID:26924049   PMID:26939003   PMID:26946078   PMID:26997267   PMID:27018294   PMID:27026702   PMID:27050391  
PMID:27061726   PMID:27114066   PMID:27152953   PMID:27163697   PMID:27176050   PMID:27222313   PMID:27231134   PMID:27233035   PMID:27285860   PMID:27467102   PMID:27486147   PMID:27506937  
PMID:27507650   PMID:27593178   PMID:27600824   PMID:27623383   PMID:27629719   PMID:27680697   PMID:27700986   PMID:27713499   PMID:27725632   PMID:27747430   PMID:27765763   PMID:27818180  
PMID:27834690   PMID:27892530   PMID:27917469   PMID:27927130   PMID:27941025   PMID:27986432   PMID:28069946   PMID:28122813   PMID:28162770   PMID:28193546   PMID:28215344   PMID:28248302  
PMID:28277539   PMID:28320863   PMID:28378742   PMID:28389470   PMID:28428003   PMID:28457749   PMID:28465231   PMID:28483380   PMID:28512198   PMID:28545113   PMID:28552735   PMID:28576970  
PMID:28600322   PMID:28630074   PMID:28671696   PMID:28775097   PMID:28791343   PMID:28865956   PMID:28893557   PMID:28960571   PMID:28977598   PMID:29058721   PMID:29088697   PMID:29114038  
PMID:29114077   PMID:29133163   PMID:29155102   PMID:29253508   PMID:29269293   PMID:29360039   PMID:29363851   PMID:29476448   PMID:29497040   PMID:29567961   PMID:29580943   PMID:29626467  
PMID:29676259   PMID:29686674   PMID:29689194   PMID:29700112   PMID:29740022   PMID:29749029   PMID:29867343   PMID:29932987   PMID:30021868   PMID:30054448   PMID:30058725   PMID:30208520  
PMID:30333726   PMID:30354240   PMID:30387892   PMID:30415836   PMID:30457570   PMID:30562941   PMID:30594931   PMID:30697954   PMID:30735546   PMID:30748033   PMID:30850274   PMID:30880553  
PMID:30888607   PMID:30950395   PMID:30992372   PMID:31060803   PMID:31118438   PMID:31145943   PMID:31149635   PMID:31195150   PMID:31219639   PMID:31257073   PMID:31300985   PMID:31302143  
PMID:31351086   PMID:31369617   PMID:31402636   PMID:31422887   PMID:31484924   PMID:31628096   PMID:31683681   PMID:31757963   PMID:31801950   PMID:31846370   PMID:31877301   PMID:31925986  
PMID:31936261   PMID:32019972   PMID:32294451   PMID:32325033   PMID:32366477   PMID:32499377   PMID:32511952   PMID:32533921   PMID:32546759   PMID:32879079   PMID:32941503  


Genomics

Comparative Map Data
Rac1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395143,491,236 - 143,513,786 (-)NCBIGRCm39mm39
GRCm385143,505,481 - 143,528,031 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5143,503,634 - 143,528,036 (-)EnsemblGRCm38mm10GRCm38
MGSCv375144,266,349 - 144,288,861 (-)NCBIGRCm37mm9NCBIm37
MGSCv365143,761,100 - 143,783,611 (-)NCBImm8
Celera5140,552,192 - 140,574,740 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map582.22NCBI
RAC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl76,374,527 - 6,403,967 (+)EnsemblGRCh38hg38GRCh38
GRCh3876,374,527 - 6,403,967 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3776,414,126 - 6,443,598 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3676,380,651 - 6,410,123 (+)NCBINCBI36hg18NCBI36
Celera76,291,529 - 6,321,004 (-)NCBI
Cytogenetic Map7p22.1NCBI
HuRef76,287,239 - 6,316,490 (+)NCBIHuRef
CHM1_176,413,683 - 6,443,197 (+)NCBICHM1_1
CRA_TCAGchr7v276,460,486 - 6,489,951 (+)NCBI
Rac1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01213,090,316 - 13,111,841 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,090,172 - 13,111,873 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01215,133,521 - 15,153,741 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,380,314 - 11,400,531 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11211,419,965 - 11,428,962 (+)NCBI
Celera1212,831,091 - 12,851,324 (+)NCBICelera
Cytogenetic Map12p11NCBI
Rac1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546013,270,159 - 13,311,351 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546013,270,159 - 13,295,562 (-)NCBIChiLan1.0ChiLan1.0
RAC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.176,559,590 - 6,599,814 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v077,039,379 - 7,068,866 (-)NCBIMhudiblu_PPA_v0panPan3
RAC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl611,655,494 - 11,757,216 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1611,726,259 - 11,758,532 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rac1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936750107,689 - 122,679 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl34,781,771 - 4,803,687 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.134,781,776 - 4,803,510 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RAC1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12815,583,609 - 15,610,753 (+)NCBI
ChlSab1.1 Ensembl2815,583,516 - 15,610,328 (+)Ensembl
Rac1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474030,912,841 - 30,933,882 (-)NCBI

Position Markers
RH125402  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385143,505,912 - 143,506,179UniSTSGRCm38
MGSCv375144,266,780 - 144,267,047UniSTSGRCm37
Celera5140,552,623 - 140,552,890UniSTS
Cytogenetic Map5G2UniSTS
cM Map582.0UniSTS
D5Ertd559e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381464,674,008 - 64,674,235UniSTSGRCm38
GRCm385143,505,577 - 143,505,811UniSTSGRCm38
MGSCv375144,266,445 - 144,266,679UniSTSGRCm37
MGSCv371465,292,845 - 65,293,072UniSTSGRCm37
Celera1462,435,842 - 62,436,077UniSTS
Celera5140,552,288 - 140,552,522UniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map14C3UniSTS
cM Map582.0UniSTS
Rac1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5G2UniSTS
cM Map582.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301362Prnr1_mprion resistance 1 (mouse)Not determined589271017146851125Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115128044149128176Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115128044149128176Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118920110151834684Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119806972149423861Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121457140151834684Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121556974151834684Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124714580151834684Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125147702151834684Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129583274151834684Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129851021151834684Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5134002093151834684Mouse
13504734Ifvrq4_minfluenza virus resistance QTL 4 (mouse)5140000000153000000Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir124a-2mmu-miR-124-3pMirtarbaseexternal_infoWestern blotNon-Functional MTI18619591
Mir124a-2mmu-miR-124-3pTarbaseexternal_infoWesternblitNEGATIVE
Mir124a-2mmu-miR-124-3pOncomiRDBexternal_infoNANA23334332
Mir142mmu-miR-142-3pOncomiRDBexternal_infoNANA21482222

Predicted Target Of
Summary Value
Count of predictions:1262
Count of miRNA genes:481
Interacting mature miRNAs:563
Transcripts:ENSMUST00000080537, ENSMUST00000100489, ENSMUST00000131513, ENSMUST00000145709
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001347530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC163995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC175091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC217112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ444803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO425367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX242948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX566679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN971018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U25107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X57277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000080537   ⟹   ENSMUSP00000079380
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5143,503,634 - 143,528,036 (-)Ensembl
RefSeq Acc Id: ENSMUST00000100489   ⟹   ENSMUSP00000098058
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5143,505,482 - 143,527,993 (-)Ensembl
RefSeq Acc Id: ENSMUST00000131513
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5143,514,669 - 143,517,608 (-)Ensembl
RefSeq Acc Id: ENSMUST00000145709
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5143,507,060 - 143,518,182 (-)Ensembl
RefSeq Acc Id: NM_001347530   ⟹   NP_001334459
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395143,491,236 - 143,513,786 (-)NCBI
GRCm385143,505,481 - 143,528,031 (-)NCBI
Sequence:
RefSeq Acc Id: NM_009007   ⟹   NP_033033
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395143,491,236 - 143,513,748 (-)NCBI
GRCm385143,505,481 - 143,527,993 (-)NCBI
MGSCv375144,266,349 - 144,288,861 (-)RGD
Celera5140,552,192 - 140,574,740 (-)RGD
cM Map5 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033033   ⟸   NM_009007
- Peptide Label: isoform 2
- UniProtKB: P63001 (UniProtKB/Swiss-Prot),   K7Q7T7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001334459   ⟸   NM_001347530
- Peptide Label: isoform 1
- UniProtKB: Q3TLP8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000098058   ⟸   ENSMUST00000100489
RefSeq Acc Id: ENSMUSP00000079380   ⟸   ENSMUST00000080537
Protein Domains
RNAse_Pc

Promoters
RGD ID:6888682
Promoter ID:EPDNEW_M7792
Type:initiation region
Name:Rac1_1
Description:Mus musculus RAS-related C3 botulinum substrate 1 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385143,527,993 - 143,528,053EPDNEW
RGD ID:6838180
Promoter ID:MM_KWN:44755
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000049002,   OTTMUST00000049003
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365144,278,411 - 144,279,477 (-)MPROMDB
RGD ID:6838179
Promoter ID:MM_KWN:44756
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000049000,   UC009AKL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365144,288,704 - 144,289,204 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97845 AgrOrtholog
Ensembl Genes ENSMUSG00000001847 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000079380 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000098058 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000080537 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000100489 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.10.130.10 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNaseA UniProtKB/TrEMBL
  RNaseA-like_dom_sf UniProtKB/TrEMBL
  RNaseA_AS UniProtKB/TrEMBL
  RNaseA_domain UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase_Rho UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97845 ENTREZGENE
NCBI Gene 19353 ENTREZGENE
PANTHER PTHR11437 UniProtKB/TrEMBL
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RnaseA UniProtKB/TrEMBL
PharmGKB RAC1 RGD
PhenoGen Rac1 PhenoGen
PRINTS RIBONUCLEASE UniProtKB/TrEMBL
PROSITE RHO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNASE_PANCREATIC UniProtKB/TrEMBL
SMART RNAse_Pc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54076 UniProtKB/TrEMBL
TIGRFAMs small_GTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.292510 ENTREZGENE
  Mm.469963 ENTREZGENE
  Mm.475073 ENTREZGENE
UniProt K7Q7T7 ENTREZGENE, UniProtKB/TrEMBL
  P63001 ENTREZGENE
  Q3TLP8 ENTREZGENE, UniProtKB/TrEMBL
  Q8BPG5_MOUSE UniProtKB/TrEMBL
  Q8C4N8_MOUSE UniProtKB/TrEMBL
  Q9D859_MOUSE UniProtKB/TrEMBL
  RAC1_MOUSE UniProtKB/Swiss-Prot
  W0UVC3_MOUSE UniProtKB/TrEMBL
UniProt Secondary O95501 UniProtKB/Swiss-Prot
  P15154 UniProtKB/Swiss-Prot
  Q9BTB4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-01 Rac1  Rac family small GTPase 1    RAS-related C3 botulinum substrate 1  Symbol and/or name change 5135510 APPROVED