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Accession:CHEBI:3048 term browser browse the term
Definition:Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.
Synonyms:exact_synonym: (3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane
 related_synonym: 3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane;   3alpha-(diphenylmethoxy)tropane;   3alpha-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane;   3endo-benzhydryloxytropane;   Benztropine;   Formula=C21H25NO;   InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+;   InChIKey=GIJXKZJWITVLHI-PMOLBWCYSA-N;   SMILES=[H][C@]1(C[C@]2([H])CC[C@]([H])(C1)N2C)OC(c1ccccc1)c1ccccc1;   benzatropina;   benzatropinum;   benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether;   tropine benzohydryl ether
 alt_id: CHEBI:661238
 xref: Beilstein:90688 "Beilstein";   CAS:86-13-5 "ChemIDplus";   CAS:86-13-5 "KEGG COMPOUND";   CAS:86-13-5 "NIST Chemistry WebBook";   DrugBank:DB00245;   Drug_Central:333 "DrugCentral";   KEGG:C06846;   KEGG:D07511
 xref_mesh: MESH:D001590
 xref: Patent:US2595405;   Wikipedia:Benzatropine

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benzatropine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            antidyskinesia agent 1130
              benzatropine 4
                benzatropine mesylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        tertiary amino compound 8521
                                          benzatropine 4
                                            benzatropine mesylate 0
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