Arhgap22 (Rho GTPase activating protein 22) - Rat Genome Database

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Gene: Arhgap22 (Rho GTPase activating protein 22) Mus musculus
Analyze
Symbol: Arhgap22
Name: Rho GTPase activating protein 22
RGD ID: 1316311
MGI Page MGI
Description: Predicted to enable GTPase activator activity. Predicted to be involved in regulation of postsynapse organization. Predicted to act upstream of or within angiogenesis and cell differentiation. Predicted to be located in cytoplasm and nucleus. Predicted to be active in glutamatergic synapse. Orthologous to human ARHGAP22 (Rho GTPase activating protein 22).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B230341L19Rik; MGC47316; p68RacGAP; RHO; rho GTPase-activating protein 22; rho-type GTPase-activating protein 22; RHOGAP2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391432,935,952 - 33,091,893 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1432,935,983 - 33,091,891 (+)EnsemblGRCm39 Ensembl
GRCm381433,213,994 - 33,369,936 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1433,214,026 - 33,369,934 (+)EnsemblGRCm38mm10GRCm38
MGSCv371434,030,009 - 34,183,122 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361432,045,915 - 32,199,025 (+)NCBIMGSCv36mm8
Celera1429,476,997 - 29,628,675 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
acetamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
chlorpyrifos  (EXP)
choline  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
dexamethasone  (EXP,ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
folic acid  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (ISO)
genistein  (EXP)
gentamycin  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
orphenadrine  (ISO)
oxaliplatin  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
propanal  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
triclosan  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:14966113   PMID:15489334   PMID:16141072   PMID:16141073   PMID:20368287   PMID:21267068   PMID:21677750  
PMID:21873635   PMID:26166575   PMID:30973865   PMID:32325033   PMID:34455539  


Genomics

Comparative Map Data
Arhgap22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391432,935,952 - 33,091,893 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1432,935,983 - 33,091,891 (+)EnsemblGRCm39 Ensembl
GRCm381433,213,994 - 33,369,936 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1433,214,026 - 33,369,934 (+)EnsemblGRCm38mm10GRCm38
MGSCv371434,030,009 - 34,183,122 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361432,045,915 - 32,199,025 (+)NCBIMGSCv36mm8
Celera1429,476,997 - 29,628,675 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.15NCBI
ARHGAP22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381048,429,831 - 48,656,265 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1048,446,036 - 48,656,265 (-)EnsemblGRCh38hg38GRCh38
GRCh371049,654,079 - 49,864,310 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361049,324,085 - 49,483,144 (-)NCBINCBI36Build 36hg18NCBI36
Build 341049,324,085 - 49,483,144NCBI
Celera1043,239,986 - 43,398,967 (-)NCBICelera
Cytogenetic Map10q11.22-q11.23NCBI
HuRef1043,918,892 - 44,129,417 (-)NCBIHuRef
CHM1_11049,935,899 - 50,146,144 (-)NCBICHM1_1
T2T-CHM13v2.01049,275,552 - 49,505,563 (-)NCBIT2T-CHM13v2.0
Arhgap22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8168,480,222 - 8,637,823 (+)NCBIGRCr8
mRatBN7.2168,473,806 - 8,631,552 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl168,476,306 - 8,631,548 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx168,600,860 - 8,650,867 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0169,745,577 - 9,795,573 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0168,595,355 - 8,645,379 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0169,454,269 - 9,613,508 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl169,486,832 - 9,613,528 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01611,414,640 - 11,572,157 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4168,863,537 - 8,913,459 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1168,866,751 - 8,913,458 (+)NCBI
Celera166,575,743 - 6,625,300 (-)NCBICelera
Cytogenetic Map16p16NCBI
Arhgap22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555561,501,773 - 1,588,604 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555561,462,366 - 1,588,589 (+)NCBIChiLan1.0ChiLan1.0
ARHGAP22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2860,676,020 - 60,925,165 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11060,682,205 - 60,930,486 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01045,589,509 - 45,833,137 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ARHGAP22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.128419,532 - 555,511 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl28419,838 - 582,548 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha28648,824 - 784,583 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.028595,180 - 731,152 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl28595,483 - 758,607 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.128394,859 - 530,643 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.028436,100 - 571,773 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.028561,465 - 697,162 (-)NCBIUU_Cfam_GSD_1.0
Arhgap22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721380,366,892 - 80,562,523 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367281,573,288 - 1,765,505 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367281,633,385 - 1,765,345 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1489,113,768 - 89,331,274 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11489,113,774 - 89,331,629 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21496,946,248 - 97,088,885 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1943,140,076 - 43,349,962 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl943,316,598 - 43,349,602 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660482,901,664 - 3,117,756 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249281,265,592 - 1,433,947 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arhgap22
5721 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1354
Count of miRNA genes:605
Interacting mature miRNAs:740
Transcripts:ENSMUST00000111955, ENSMUST00000111956, ENSMUST00000131086, ENSMUST00000132659, ENSMUST00000137590, ENSMUST00000140166, ENSMUST00000140711, ENSMUST00000165792
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301991Wta3_mweight adult 3 (mouse)Not determined14388747337887650Mouse
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined514347339143596Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined992324548765082Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141221287146213007Mouse
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)141376927346737457Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)141376927347237457Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141516061649160765Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141882760452827726Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142792195761137449Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142999699463997133Mouse
27226775Tibl7_mtibia length 7, 5 week (mouse)143032195748837457Mouse
27226744Metcl6_mmetatarsal-calcaneal length 6, 5 week (mouse)143032195752937457Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143033525064335381Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143033525064335381Mouse

Markers in Region
D14Mit175  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381433,256,211 - 33,256,349UniSTSGRCm38
MGSCv371434,069,397 - 34,069,535UniSTSGRCm37
Celera1429,512,801 - 29,512,939UniSTS
Cytogenetic Map14BUniSTS
cM Map1411.5UniSTS
Whitehead Genetic1418.6UniSTS
D14Mit188  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381433,252,079 - 33,252,190UniSTSGRCm38
MGSCv371434,065,265 - 34,065,376UniSTSGRCm37
Cytogenetic Map14BUniSTS
cM Map1411.5UniSTS
Whitehead Genetic1418.6UniSTS
Whitehead_YAC14 UniSTS
fb36d11.x1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381433,320,645 - 33,322,276UniSTSGRCm38
MGSCv371434,133,831 - 34,135,462UniSTSGRCm37
Celera1429,577,436 - 29,579,067UniSTS
Cytogenetic Map14BUniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_153800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036158588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036158589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003950847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004938393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004938394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC154239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY541447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB370610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC038272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000111955   ⟹   ENSMUSP00000107586
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,041,660 - 33,091,891 (+)Ensembl
GRCm38.p6 Ensembl1433,319,703 - 33,369,934 (+)Ensembl
RefSeq Acc Id: ENSMUST00000111956   ⟹   ENSMUSP00000107587
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1432,938,780 - 33,091,891 (+)Ensembl
GRCm38.p6 Ensembl1433,216,823 - 33,369,934 (+)Ensembl
RefSeq Acc Id: ENSMUST00000131086   ⟹   ENSMUSP00000154002
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1432,972,347 - 33,065,260 (+)Ensembl
GRCm38.p6 Ensembl1433,250,390 - 33,343,303 (+)Ensembl
RefSeq Acc Id: ENSMUST00000132659
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,084,333 - 33,085,282 (+)Ensembl
GRCm38.p6 Ensembl1433,362,376 - 33,363,325 (+)Ensembl
RefSeq Acc Id: ENSMUST00000137590
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,028,075 - 33,091,889 (+)Ensembl
GRCm38.p6 Ensembl1433,306,118 - 33,369,932 (+)Ensembl
RefSeq Acc Id: ENSMUST00000140166
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,084,254 - 33,086,433 (+)Ensembl
GRCm38.p6 Ensembl1433,362,297 - 33,364,476 (+)Ensembl
RefSeq Acc Id: ENSMUST00000140711   ⟹   ENSMUSP00000154670
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,073,269 - 33,085,237 (+)Ensembl
GRCm38.p6 Ensembl1433,351,312 - 33,363,280 (+)Ensembl
RefSeq Acc Id: ENSMUST00000165792   ⟹   ENSMUSP00000153801
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1432,935,983 - 32,939,066 (+)Ensembl
GRCm38.p6 Ensembl1433,214,026 - 33,217,109 (+)Ensembl
RefSeq Acc Id: NM_153800   ⟹   NP_722495
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,938,780 - 33,091,893 (+)NCBI
GRCm381433,216,823 - 33,369,936 (+)NCBI
MGSCv371434,030,009 - 34,183,122 (+)RGD
Celera1429,476,997 - 29,628,675 (+)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006518954   ⟹   XP_006519017
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,984,442 - 33,091,893 (+)NCBI
GRCm381433,262,469 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006518956   ⟹   XP_006519019
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,935,968 - 33,091,893 (+)NCBI
GRCm381433,214,005 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006518957   ⟹   XP_006519020
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,972,238 - 33,091,893 (+)NCBI
GRCm381433,250,127 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006518959   ⟹   XP_006519022
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,041,491 - 33,091,893 (+)NCBI
GRCm381433,319,526 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006518960   ⟹   XP_006519023
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,059,371 - 33,091,893 (+)NCBI
GRCm381433,337,411 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006518961   ⟹   XP_006519024
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,041,493 - 33,091,893 (+)NCBI
GRCm381433,319,528 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006518962   ⟹   XP_006519025
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,059,372 - 33,091,893 (+)NCBI
GRCm381433,337,412 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006518963   ⟹   XP_006519026
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,072,787 - 33,091,893 (+)NCBI
GRCm381433,350,838 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011245053   ⟹   XP_011243355
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,935,969 - 33,091,893 (+)NCBI
GRCm381433,213,994 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011245054   ⟹   XP_011243356
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,081,162 - 33,091,893 (+)NCBI
GRCm381433,359,205 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017316004   ⟹   XP_017171493
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,984,444 - 33,091,893 (+)NCBI
GRCm381433,262,473 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017316006   ⟹   XP_017171495
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,984,446 - 33,091,893 (+)NCBI
GRCm381433,262,476 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030247787   ⟹   XP_030103647
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,972,242 - 33,091,893 (+)NCBI
GRCm381433,250,278 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036158588   ⟹   XP_036014481
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,938,561 - 33,091,893 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036158589   ⟹   XP_036014482
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,041,494 - 33,091,893 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003950847
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,984,178 - 33,091,893 (+)NCBI
GRCm381433,262,210 - 33,369,936 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004938393
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,984,188 - 33,091,893 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004938394
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391432,935,952 - 33,091,893 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_722495   ⟸   NM_153800
- UniProtKB: Q8BVH4 (UniProtKB/Swiss-Prot),   Q6QHH6 (UniProtKB/Swiss-Prot),   Q8CHY5 (UniProtKB/Swiss-Prot),   Q8BL80 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006519019   ⟸   XM_006518956
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006519020   ⟸   XM_006518957
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006519017   ⟸   XM_006518954
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006519022   ⟸   XM_006518959
- Peptide Label: isoform X8
- UniProtKB: D3Z1Y5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006519024   ⟸   XM_006518961
- Peptide Label: isoform X10
- UniProtKB: D3Z1Y5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006519023   ⟸   XM_006518960
- Peptide Label: isoform X9
- UniProtKB: D3Z1Y5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006519025   ⟸   XM_006518962
- Peptide Label: isoform X11
- UniProtKB: D3Z1Y5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006519026   ⟸   XM_006518963
- Peptide Label: isoform X12
- UniProtKB: D3Z1Y5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011243355   ⟸   XM_011245053
- Peptide Label: isoform X5
- UniProtKB: Q8BVH4 (UniProtKB/Swiss-Prot),   Q6QHH6 (UniProtKB/Swiss-Prot),   Q8CHY5 (UniProtKB/Swiss-Prot),   Q8BL80 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011243356   ⟸   XM_011245054
- Peptide Label: isoform X14
- Sequence:
RefSeq Acc Id: XP_017171493   ⟸   XM_017316004
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017171495   ⟸   XM_017316006
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_030103647   ⟸   XM_030247787
- Peptide Label: isoform X6
RefSeq Acc Id: ENSMUSP00000107586   ⟸   ENSMUST00000111955
RefSeq Acc Id: ENSMUSP00000107587   ⟸   ENSMUST00000111956
RefSeq Acc Id: ENSMUSP00000154002   ⟸   ENSMUST00000131086
RefSeq Acc Id: ENSMUSP00000153801   ⟸   ENSMUST00000165792
RefSeq Acc Id: ENSMUSP00000154670   ⟸   ENSMUST00000140711
RefSeq Acc Id: XP_036014481   ⟸   XM_036158588
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036014482   ⟸   XM_036158589
- Peptide Label: isoform X13
- UniProtKB: D3Z1Y5 (UniProtKB/TrEMBL)
Protein Domains
PH   Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BL80-F1-model_v2 AlphaFold Q8BL80 1-702 view protein structure

Promoters
RGD ID:8681892
Promoter ID:EPDNEW_M18977
Type:initiation region
Name:Arhgap22_1
Description:Mus musculus Rho GTPase activating protein 22 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18978  EPDNEW_M18979  EPDNEW_M18980  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381433,216,876 - 33,216,936EPDNEW
RGD ID:8681894
Promoter ID:EPDNEW_M18978
Type:single initiation site
Name:Arhgap22_4
Description:Mus musculus Rho GTPase activating protein 22 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18977  EPDNEW_M18979  EPDNEW_M18980  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381433,306,060 - 33,306,120EPDNEW
RGD ID:8681896
Promoter ID:EPDNEW_M18979
Type:multiple initiation site
Name:Arhgap22_2
Description:Mus musculus Rho GTPase activating protein 22 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18977  EPDNEW_M18978  EPDNEW_M18980  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381433,319,744 - 33,319,804EPDNEW
RGD ID:8681898
Promoter ID:EPDNEW_M18980
Type:multiple initiation site
Name:Arhgap22_3
Description:Mus musculus Rho GTPase activating protein 22 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18977  EPDNEW_M18978  EPDNEW_M18979  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381433,337,437 - 33,337,497EPDNEW
RGD ID:6824697
Promoter ID:MM_KWN:16164
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:ENSMUST00000068112,   NM_153800
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361434,029,646 - 34,030,146 (+)MPROMDB
RGD ID:6824700
Promoter ID:MM_KWN:16165
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   Brain,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000055601
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361434,062,846 - 34,063,952 (+)MPROMDB
RGD ID:6824703
Promoter ID:MM_KWN:16166
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:UC007SZN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361434,118,746 - 34,119,246 (+)MPROMDB
RGD ID:6824698
Promoter ID:MM_KWN:16167
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney
Transcripts:ENSMUST00000111955
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361434,133,011 - 34,133,511 (+)MPROMDB
RGD ID:6824701
Promoter ID:MM_KWN:16168
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Lung
Transcripts:OTTMUST00000055602
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361434,164,096 - 34,164,782 (+)MPROMDB
RGD ID:6847086
Promoter ID:MM_ACW:15564
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:ARHGAP22.ISEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361434,172,396 - 34,172,896 (+)MPROMDB
RGD ID:6824702
Promoter ID:MM_KWN:16169
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:OTTMUST00000055603,   OTTMUST00000055604
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361434,175,096 - 34,175,596 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2443418 AgrOrtholog
Ensembl Genes ENSMUSG00000063506 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000111955 ENTREZGENE
  ENSMUST00000111955.2 UniProtKB/TrEMBL
  ENSMUST00000111956 ENTREZGENE
  ENSMUST00000111956.9 UniProtKB/Swiss-Prot
  ENSMUST00000131086.3 UniProtKB/TrEMBL
  ENSMUST00000137590 ENTREZGENE
  ENSMUST00000140711.3 UniProtKB/TrEMBL
  ENSMUST00000165792.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:239027 UniProtKB/Swiss-Prot
MGD MGI:2443418 ENTREZGENE
NCBI Gene 239027 ENTREZGENE
PANTHER RHO GTPASE-ACTIVATING PROTEIN 22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPERMATHECAL PHYSIOLOGY VARIANT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arhgap22 PhenoGen
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHOGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2I3BPI8_MOUSE UniProtKB/TrEMBL
  A0A2I3BQ18_MOUSE UniProtKB/TrEMBL
  A0A2I3BRZ0_MOUSE UniProtKB/TrEMBL
  D3Z1Y5 ENTREZGENE, UniProtKB/TrEMBL
  Q6QHH6 ENTREZGENE
  Q8BL80 ENTREZGENE
  Q8BVH4 ENTREZGENE
  Q8CHY5 ENTREZGENE
  RHG22_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q6QHH6 UniProtKB/Swiss-Prot
  Q8BVH4 UniProtKB/Swiss-Prot
  Q8CHY5 UniProtKB/Swiss-Prot