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Gene: Cblc (Casitas B-lineage lymphoma c) Mus musculus
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Symbol: Cblc
Name: Casitas B-lineage lymphoma c
Description: Predicted to have several functions, including SH3 domain binding activity; phosphotyrosine residue binding activity; and signaling receptor binding activity. Predicted to be involved in cellular protein metabolic process; negative regulation of protein kinase activity; and signal transduction. Predicted to localize to the membrane raft; plasma membrane; and ubiquitin ligase complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; lung; and sensory organ. Orthologous to human CBLC (Cbl proto-oncogene C); PARTICIPATES IN chronic myeloid leukemia pathway; endocytosis pathway; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310076I21Rik; 2310079L19Rik; CBL-3; Cbl3; E3 ubiquitin-protein ligase CBL-C; MGC117886; RING-type E3 ubiquitin transferase CBL-C; SH3-binding protein CBL-3; SH3-binding protein CBL-C; signal transduction protein CBL-C
Orthologs:
Homo sapiens (human) : CBLC (Cbl proto-oncogene C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cblc (Cbl proto-oncogene C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cblc (Cbl proto-oncogene C)
Pan paniscus (bonobo/pygmy chimpanzee) : CBLC (Cbl proto-oncogene C)
Canis lupus familiaris (dog) : CBLC (Cbl proto-oncogene C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cblc (Cbl proto-oncogene C)
Sus scrofa (pig) : CBLC (Cbl proto-oncogene C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38719,779,718 - 19,796,809 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37720,365,067 - 20,382,158 (-)NCBIGRCm37mm9NCBIm37
MGSCv36718,938,242 - 18,955,331 (-)NCBImm8
Celera717,187,514 - 17,204,632 (-)NCBICelera
Cytogenetic Map7 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cblc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316967
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.