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Gene: Cblc (Casitas B-lineage lymphoma c) Mus musculus
Symbol: Cblc
Name: Casitas B-lineage lymphoma c
Description: Predicted to have several functions, including SH3 domain binding activity; phosphotyrosine residue binding activity; and signaling receptor binding activity. Predicted to be involved in cellular protein metabolic process; negative regulation of protein kinase activity; and signal transduction. Predicted to localize to the membrane raft; plasma membrane; and ubiquitin ligase complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; lung; and sensory organ. Orthologous to human CBLC (Cbl proto-oncogene C); PARTICIPATES IN chronic myeloid leukemia pathway; endocytosis pathway; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310076I21Rik; 2310079L19Rik; CBL-3; Cbl3; E3 ubiquitin-protein ligase CBL-C; MGC117886; RING-type E3 ubiquitin transferase CBL-C; SH3-binding protein CBL-3; SH3-binding protein CBL-C; signal transduction protein CBL-C
Homo sapiens (human) : CBLC (Cbl proto-oncogene C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cblc (Cbl proto-oncogene C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cblc (Cbl proto-oncogene C)
Pan paniscus (bonobo/pygmy chimpanzee) : CBLC (Cbl proto-oncogene C)
Canis lupus familiaris (dog) : CBLC (Cbl proto-oncogene C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cblc (Cbl proto-oncogene C)
Sus scrofa (pig) : CBLC (Cbl proto-oncogene C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38719,779,718 - 19,796,809 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37720,365,067 - 20,382,158 (-)NCBIGRCm37mm9NCBIm37
MGSCv36718,938,242 - 18,955,331 (-)NCBImm8
Celera717,187,514 - 17,204,632 (-)NCBICelera
Cytogenetic Map7 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cblc
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316967
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.