Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dpp3 | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPP3 mRNA | CTD | PMID:22206623 | Dpp3 | Mouse | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DPP3 mRNA | CTD | PMID:17942748 | Dpp3 | Mouse | 17beta-estradiol | increases expression | ISO | Dpp3 (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of DPP3 protein | CTD | PMID:32145629 | Dpp3 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DPP3 mRNA | CTD | PMID:17942748 | Dpp3 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of DPP3 mRNA | CTD | PMID:21570461 | Dpp3 | Mouse | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of DPP3 mRNA | CTD | PMID:20188158 | Dpp3 | Mouse | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of DPP3 gene | CTD | PMID:31683443 | Dpp3 | Mouse | acetamide | decreases expression | ISO | Dpp3 (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of DPP3 mRNA | CTD | PMID:31881176 | Dpp3 | Mouse | aflatoxin B1 | decreases methylation | ISO | DPP3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of DPP3 intron | CTD | PMID:30157460 | Dpp3 | Mouse | ammonium chloride | affects expression | ISO | Dpp3 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of DPP3 mRNA | CTD | PMID:16483693 | Dpp3 | Mouse | aristolochic acid A | increases expression | ISO | DPP3 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of DPP3 protein | CTD | PMID:33212167 | Dpp3 | Mouse | benzatropine | multiple interactions | ISO | DPP3 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in decreased expression of DPP3 protein | CTD | PMID:34122009 | Dpp3 | Mouse | benzo[a]pyrene | affects methylation | ISO | DPP3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of DPP3 intron | CTD | PMID:30157460 | Dpp3 | Mouse | benzo[a]pyrene | increases methylation | ISO | DPP3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of DPP3 5' UTR | CTD | PMID:27901495 | Dpp3 | Mouse | Benzo[k]fluoranthene | decreases expression | EXP | | 6480464 | benzo(k)fluoranthene results in decreased expression of DPP3 mRNA | CTD | PMID:26377693 | Dpp3 | Mouse | beta-lapachone | increases expression | ISO | DPP3 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of DPP3 mRNA | CTD | PMID:38218311 | Dpp3 | Mouse | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DPP3 protein | CTD | PMID:18418863 | Dpp3 | Mouse | bisphenol A | decreases expression | ISO | Dpp3 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of DPP3 mRNA | CTD | PMID:30816183 more ... | Dpp3 | Mouse | bisphenol A | increases expression | ISO | Dpp3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of DPP3 mRNA and bisphenol A results in increased expression of DPP3 protein | CTD | PMID:25181051 and PMID:32145629 | Dpp3 | Mouse | bisphenol F | increases expression | ISO | DPP3 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of DPP3 protein | CTD | PMID:34186270 | Dpp3 | Mouse | capsaicin | decreases expression | ISO | Dpp3 (Rattus norvegicus) | 6480464 | Capsaicin results in decreased expression of DPP3 mRNA | CTD | PMID:20349343 | Dpp3 | Mouse | cisplatin | multiple interactions | ISO | DPP3 (Homo sapiens) | 6480464 | Cisplatin inhibits the reaction [Piroxicam results in decreased expression of DPP3 mRNA] | CTD | PMID:21858171 | Dpp3 | Mouse | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of DPP3 mRNA | CTD | PMID:17585979 | Dpp3 | Mouse | clozapine | multiple interactions | ISO | DPP3 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Clozapine] results in decreased expression of DPP3 protein | CTD | PMID:34122009 | Dpp3 | Mouse | Cuprizon | multiple interactions | ISO | DPP3 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in decreased expression of DPP3 protein and [Cuprizone co-treated with Clozapine] results in decreased expression of DPP3 protein | CTD | PMID:34122009 | Dpp3 | Mouse | cyclosporin A | decreases expression | ISO | DPP3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of DPP3 mRNA | CTD | PMID:20106945 | Dpp3 | Mouse | Dibutyl phosphate | affects expression | ISO | DPP3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of DPP3 mRNA | CTD | PMID:37042841 | Dpp3 | Mouse | dibutyl phthalate | decreases expression | ISO | Dpp3 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in decreased expression of DPP3 mRNA | CTD | PMID:21266533 | Dpp3 | Mouse | disodium selenite | increases expression | ISO | DPP3 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of DPP3 mRNA | CTD | PMID:18175754 | Dpp3 | Mouse | doxorubicin | affects expression | ISO | DPP3 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of DPP3 protein | CTD | PMID:29385562 | Dpp3 | Mouse | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of DPP3 mRNA | CTD | PMID:35436446 | Dpp3 | Mouse | fenthion | decreases expression | EXP | | 6480464 | Fenthion results in decreased expression of DPP3 mRNA | CTD | PMID:34813904 | Dpp3 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPP3 mRNA | CTD | PMID:22206623 | Dpp3 | Mouse | gentamycin | decreases expression | ISO | Dpp3 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of DPP3 mRNA | CTD | PMID:33387578 | Dpp3 | Mouse | hydrogen peroxide | decreases response to substance | ISO | DPP3 (Homo sapiens) | 6480464 | DPP3 protein results in decreased susceptibility to Hydrogen Peroxide | CTD | PMID:17360324 | Dpp3 | Mouse | isotretinoin | decreases expression | ISO | DPP3 (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of DPP3 mRNA | CTD | PMID:20436886 | Dpp3 | Mouse | Leu-enkephalin | increases cleavage | ISO | DPP3 (Homo sapiens) | 6480464 | DPP3 protein results in increased cleavage of Enkephalin and Leucine | CTD | PMID:10873616 | Dpp3 | Mouse | Leu-enkephalin | multiple interactions | ISO | DPP3 (Homo sapiens) | 6480464 | spinorphin inhibits the reaction [DPP3 protein results in increased cleavage of Enkephalin more ... | CTD | PMID:10873616 | Dpp3 | Mouse | LY294002 | multiple interactions | ISO | DPP3 (Homo sapiens) | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [DPP3 protein results in increased expression of NQO1 protein] | CTD | PMID:17360324 | Dpp3 | Mouse | microcystin-LR | increases expression | ISO | Dpp3 (Rattus norvegicus) | 6480464 | cyanoginosin LR results in increased expression of DPP3 protein | CTD | PMID:22430071 | Dpp3 | Mouse | nickel atom | increases expression | ISO | DPP3 (Homo sapiens) | 6480464 | Nickel results in increased expression of DPP3 mRNA | CTD | PMID:25583101 | Dpp3 | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of DPP3 mRNA | CTD | PMID:17562736 | Dpp3 | Mouse | paracetamol | increases expression | ISO | DPP3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of DPP3 mRNA | CTD | PMID:22230336 | Dpp3 | Mouse | piroxicam | decreases expression | ISO | DPP3 (Homo sapiens) | 6480464 | Piroxicam results in decreased expression of DPP3 mRNA | CTD | PMID:21858171 | Dpp3 | Mouse | piroxicam | multiple interactions | ISO | DPP3 (Homo sapiens) | 6480464 | Cisplatin inhibits the reaction [Piroxicam results in decreased expression of DPP3 mRNA] | CTD | PMID:21858171 | Dpp3 | Mouse | quinolinic acid | multiple interactions | ISO | Dpp3 (Rattus norvegicus) | 6480464 | Quinolinic Acid promotes the reaction [DPP3 protein binds to KEAP1 protein] | CTD | PMID:30876764 | Dpp3 | Mouse | Ro 31-8220 | multiple interactions | ISO | DPP3 (Homo sapiens) | 6480464 | Ro 31-8220 inhibits the reaction [DPP3 protein results in increased expression of NQO1 protein] | CTD | PMID:17360324 | Dpp3 | Mouse | rotenone | decreases response to substance | ISO | DPP3 (Homo sapiens) | 6480464 | DPP3 protein results in decreased susceptibility to Rotenone | CTD | PMID:17360324 | Dpp3 | Mouse | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of DPP3 mRNA | CTD | PMID:16014739 | Dpp3 | Mouse | sodium arsenite | increases expression | ISO | DPP3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of DPP3 mRNA | CTD | PMID:34032870 | Dpp3 | Mouse | sodium fluoride | increases expression | EXP | | 6480464 | Sodium Fluoride results in increased expression of DPP3 protein | CTD | PMID:28918527 | Dpp3 | Mouse | Spinorphin | multiple interactions | ISO | DPP3 (Homo sapiens) | 6480464 | spinorphin inhibits the reaction [DPP3 protein results in increased cleavage of Enkephalin and Leucine] | CTD | PMID:10873616 | Dpp3 | Mouse | sunitinib | decreases expression | ISO | DPP3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of DPP3 mRNA | CTD | PMID:31533062 | Dpp3 | Mouse | tetrachloromethane | decreases expression | ISO | Dpp3 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of DPP3 mRNA | CTD | PMID:16239168 | Dpp3 | Mouse | tetrahydropalmatine | decreases expression | ISO | DPP3 (Homo sapiens) | 6480464 | tetrahydropalmatine results in decreased expression of DPP3 protein | CTD | PMID:20109541 | Dpp3 | Mouse | thioacetamide | decreases expression | ISO | Dpp3 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of DPP3 mRNA | CTD | PMID:34492290 | Dpp3 | Mouse | titanium dioxide | decreases methylation | EXP | | 6480464 | titanium dioxide results in decreased methylation of DPP3 gene and titanium dioxide results in decreased methylation of DPP3 promoter | CTD | PMID:35295148 | Dpp3 | Mouse | tunicamycin | decreases expression | ISO | DPP3 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of DPP3 mRNA | CTD | PMID:22378314 | Dpp3 | Mouse | valproic acid | decreases expression | ISO | DPP3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DPP3 mRNA | CTD | PMID:29154799 | Dpp3 | Mouse | valproic acid | affects expression | ISO | DPP3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DPP3 mRNA | CTD | PMID:25979313 | |