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Gene: Psmc1 (protease (prosome, macropain) 26S subunit, ATPase 1) Mus musculus
Symbol: Psmc1
Name: protease (prosome, macropain) 26S subunit, ATPase 1
Description: Predicted to have TBP-class protein binding activity and proteasome-activating ATPase activity. Involved in negative regulation of neuron death. Localizes to the proteasome regulatory particle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human PSMC1 (proteasome 26S subunit, ATPase 1); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione.
Type: protein-coding
Also known as: 26S protease regulatory subunit 4; 26S proteasome AAA-ATPase subunit RPT2; 26S proteasome regulatory subunit 4; AI325227; P26s4; proteasome 26S subunit ATPase 1; rpt2; Rpt2/S4; S4
Homo sapiens (human) : PSMC1 (proteasome 26S subunit, ATPase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Psmc1 (proteasome 26S subunit, ATPase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psmc1 (proteasome 26S subunit, ATPase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PSMC1 (proteasome 26S subunit, ATPase 1)
Canis lupus familiaris (dog) : PSMC1 (proteasome 26S subunit, ATPase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psmc1 (proteasome 26S subunit, ATPase 1)
Sus scrofa (pig) : PSMC1 (proteasome 26S subunit, ATPase 1)
Chlorocebus sabaeus (African green monkey) : PSMC1 (proteasome 26S subunit, ATPase 1)
Heterocephalus glaber (naked mole-rat) : Psmc1 (proteasome 26S subunit, ATPase 1)
more info ...
Related Pseudogenes: Gm12288   Gm9067   Gm9575   Psmc1-rs1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl12100,110,154 - 100,123,405 (+)Ensembl
GRCm3812100,110,202 - 100,123,364 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712101,348,412 - 101,361,574 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612100,511,252 - 100,524,414 (+)NCBImm8
Celera12101,336,798 - 101,349,996 (+)NCBICelera
Cytogenetic Map12 ENCBI
cM Map1250.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Psmc1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734426
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.