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(+)-schisandrin B  
(+)-sesamin +   
(+)-SKF-10,047 
(-)-cotinine +   
(-)-epigallocatechin 3-gallate +   
(-)-N(6)-(2-phenylisopropyl)adenosine 
(-)-secoisolariciresinol +   
(1R,2S)-nortilidine +  
(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol 
(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride  
(25R)-cholest-5-ene-3beta,26-diol +   
(2R,3S)-PPDA +  
(2S,3R)-PPDA +  
(3R,4S,1'R)-3-(1'-hydroxyethyl)-4-methyldihydrofuran-2(3H)-one 
(E,E)-germacrone  
(R)-fluoxetine +   
(R)-fluoxetine hydrochloride +   
(R)-ketamine 
(R,R)-5,11-diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol 
(R,R)-tramadol +   
(R,R)-tramadol hydrochloride +  
(S)-(-)-sulpiride 
(S)-amphetamine +   
(S)-carbinoxamine maleate 
(S)-duloxetine hydrochloride  
(S)-fluoxetine +   
(S)-fluoxetine hydrochloride +   
(S,S)-tramadol +   
(S,S)-tramadol hydrochloride +  
1,3-dimethyladamantane +  
1-(1-phenylcyclopentyl)methylamine 
1-hexanamine 
1-hydroxy-5-phenyl-3-pentanone 
1-isothiocyanato-6-(methylsulfanyl)hexane 
1-methyladamantane +  
2,4-dimethylpentan-3-amine 
2-amino-5-phosphonopentanoic acid  
2-hexanamine 
2-isopropylaminoethylamine 
2-methylbutan-2-amine 
3-(2-ethylhexoxy)propan-1-amine 
3-[(4-aminobutyl)amino]propanal 
3-hydroxymethyl-4-methyl-furan-2(5H)-one 
3-iodothyronamine  
4-(1-benzofuran-2-yl)pyridine 
4-amino-TEMPO +   
4-hydroxy-TEMPO +   
4-Propylcyclohexylamine 
5,5-dimethyl-1-pyrroline N-oxide  
5-methoxytryptamine +   
6alpha-methylprednisolone +   
7,8-dihydroxyflavone +  
7-chlorokynurenic acid  
7-ketocholesterol  
7alpha-hydroxypregnenolone 
7beta-hydroxyepiandrosterone 
8-Br-cAMP  
Ac-Tyr-Val-Ala-Asp-chloromethylketone 
acteoside  
adamantan-1-aminium +  
adamantan-2-yl group 
adamantane +   
adamantanol +  
adamantanones +  
adapalene  
adinazolam  
ajugaciliatin B 
ajugamarin A1 chlorohydrin 
ajugamarin A2 chlorohydrin 
akebia saponin D 
albiflorin +   
all-cis-5,8,11,14,17-icosapentaenoic acid +  
alliin +   
alliin zwitterion 
alpha-tocotrienol  
AM-251  
amantadine  
amantadine hydrochloride 
amantadine sulfate 
amburoside A 
amineptine +  
amitriptyline +   
AMN082 dihydrochloride 
amoxapine  
amphetamine +   
ANA-12 
anacardic acid 
ananolignan F 
ananolignan L 
apelin-12 
apelin-13 
apomorphine +   
aprepitant  
arachidonyl-2'-chloroethylamide  
argon(0) 
arterolane 
aspernigrin B 
aspirin-triggered protectin D1 
astragaloside IV  
astressin  
atomoxetine +   
atomoxetine hydrochloride  
auraptene  
azure B  
baicalin  
BAY 73-6691 
benserazide  
benserazide hydrochloride 
benzatropine +   
benzatropine mesylate 
biperiden +   
biperiden hydrochloride 
bis(7)-tacrine 
bis-(4-hydroxybenzyl)sulfide 
brexanolone 
bromocriptine +   
bromocriptine methanesulfonate 
bupropion +   
butan-1-amine +   
cabergoline  
cannabigerol  
carbidopa  
carbidopa (anhydrous) +   
carbinoxamine +   
carbinoxamine maleate +  
carnosine +   
CD437 +   
CDP-choline  
CGP 78608 
CGP 78608 hydrochloride 
CGP-42112A  
chlorphenamine +   
choline alfoscerate 
cilostazol  
citalopram  
citalopram hydrobromide 
clomipramine  
clomipramine hydrochloride 
clorgyline  
clovoxamine 
CORM 3 
creatine +   
curcumin +   
cyanidin cation +   
Cycloate 
cyclobenzaprine +   
cyclobenzaprine hydrochloride 
cyclohexane-1,2-diamine 
cycloheximide  
cyclohexylamine 
cyclopropylamine +  
cycrimine +  
cycrimine hydrochloride +  
dantrolene  
Delta(9)-tetrahydrocannabinolic acid  
desipramine +   
desmethyldoxepin +  
dexamisole +  
dextromethadone +   
dextromethorphan +   
Dicyclohexylamine 
dihydrolipoic acid +   
dimethyloxalylglycine 
dinitrogen oxide  
diphenhydramine +   
diphenhydramine hydrochloride 
dizocilpine  
dizocilpine maleate  
dodecylamine +   
dopamine +   
dopamine agonist +   
dopamine uptake inhibitor +   
dopaminergic antagonist +   
dothiepin +   
dothiepin hydrochloride +  
doxepin +   
ebselen  
eliprodil  
entacapone +   
escitalopram +   
escitalopram hydrobromide +  
esketamine +   
esketamine hydrochloride 
etazolate  
ethanol +   
ethoxyquin  
ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate 
ethylamine +   
ethylisopropylamiloride  
fangchinoline  
fasudil  
fasudil hydrochloride +  
fasudil hydrochloride hydrate 
felbamate  
ferrostatin-1 +   
flavalin A 
flavalin B 
flibanserin 
fluoxetine  
fluoxetine hydrochloride  
flupenthixol +   
fluvoxamine  
foscarbidopa +  
foslevodopa +  
fucoxanthin  
galgravin 
gepirone 
gepirone hydrochloride 
ginkgolide B  
ginsenoside Rb1  
ginsenoside Rb3 
ginsenoside Rd +   
ginsenoside Re  
ginsenoside Rg1  
Glu-Asp-Arg 
glycoursodeoxycholic acid  
gossypin  
GSK126 
hinokiflavone  
huperzine A  
hydroxysafflor yellow A  
hyperforin  
hypericin +   
ilomastat  
imipramine +   
imipramine hydrochloride 
indirubin-3'-monoxime  
interiotherin C 
isoliquiritigenin +   
isopentylamine 
isopropylamine 
jaspamide  
juglanin A 
kaempferol 3,7-di-O-alpha-L-rhamnoside 
ketamine +   
ketamine hydrochloride +  
ketone body +   
KU-55933 
kynurenic acid +   
L-2-aminopentanoic acid 
L-779976 
L-817818 
L-dopa +  
L-tryptophan +   
lamotrigine  
lanthionine ketimine 
leucettine L41 
levomefolate calcium 
levomethadone +   
liraglutide  
lisuride +   
lithium citrate tetrahydrate 
lithium sulfate  
lixisenatide  
lofepramine +   
lofepramine hydrochloride 
loganin +   
LY 379268  
LY-367,265 
maysin 
Mecamylamine  
meldonium  
melittin  
memantine  
A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
memantine hydrochloride 
menaquinone-4 +   
mesulergine  
methadone +   
methanol extract of Sorbus alnifolia 
methyl 3,4-dihydroxybenzoate 
methylamine +   
methylene blue  
methylparaben  
metixene +   
mianserin +   
michigazone 
midafotel 
minaprine +  
miquelianin  
moclobemide  
morin  
N(1)-isopropyl-2-methylpropan-1,2-diamine 
N(5)-ethyl-L-glutamine  
N,N'-bis(diphenylmethyl)ethane-1,2-diamine 
N-(3-aminopropyl)-4-aminobutanal 
N-[2-(4-phenoxybenzyl)benzimidazol-5-yl]methanesulfonamide 
N-\{2-[(4-benzylpiperidin-1-yl)methyl]benzimidazol-5-yl\}methanesulfonamide 
N-acetylphenylalanine +  
N-arachidonoyl-L-serine 
N-benzylhexadecanamide 
N-palmitoyl-S-[2,3-bis(palmitoyloxy)propyl]-Cys-Ser-Lys-Lys-Lys-Lys  
N-tert-butyl(3,5,6-trimethylpyrazin-2-yl)methanimine N-oxide 
naxagolide 
naxagolide hydrochloride 
necrosulfonamide 
nefazodone +   
neriifolin +  
nerolidol +   
nicotinamide +   
nisoxetine  
NNC 55-0396 (free base) +  
NNC 55-0396 dihydrochloride 
norgestrel  
noribogaine 
nortriptyline  
Noruron 
notoginsenoside R1  
O-desmethylvenlafaxine 
octadecan-1-amine 
octan-1-amine 
oleocanthal 
oleuropein aglycone 
orphenadrine +   
orphenadrine citrate 
orphenadrine hydrochloride 
p-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe 
paliperidone 
paliperidone palmitate  
palmitoyl ethanolamide  
paroxetine +   
paroxetine hydrochloride 
paroxetine maleate 
pentamidine  
pentan-1-amine 
pentan-3-amine 
perfluoro-1-methyladamantane 
perfluoroadamantane 
pergolide  
pergolide mesylate 
phencyclidine  
phenethyl caffeate  
phentermine +   
pinocembrin +   
pioglitazone +   
piroheptine 
piroheptine hydrochloride 
PJ34  
PJ34 hydrochloride 
PPDA 
pramipexole  
pramipexole hydrochloride 
pramipexole hydrochloride anhydrous +  
pridinol  
procyclidine +   
profenamine +   
profenamine hydrochloride 
protectin D1 +  
protriptyline +   
protriptyline hydrochloride 
pterostilbene  
pyrrolidine dithiocarbamate  
rasagiline  
RGFP966  
rifampicin +   
ritanserin  
rivastigmine  
rivastigmine tartrate 
Ro 25-6981  
Ro 25-6981 maleate 
rolicyclidine 
rolipram +   
ropinirole  
rubidium chloride 
rubimaillin  
S-methyl-L-thiocitrulline  
salvianolic acid B  
salvigenin  
saxagliptin +   
SB 203580  
SB 415286  
scopolamine +   
sec-butylamine +  
selegiline hydrochloride 
semaglutide  
sertraline  
sertraline hydrochloride 
SL-327  
SMIP004 
sodium phenylbutyrate 
Spenolimycin 
SRS16-86 
St. John's wort extract 
SU4312 
sulpiride +   
sunitinib +   
syringin  
taltirelin +  
tandospirone 
tandospirone citrate  
tauroursodeoxycholic acid  
TDZD-8 
tenocyclidine 
teprenone  
tert-butylamine 
tetracyclic antidepressant +   
tetrahydroxycurcumin 
tetramethylpyrazine  
tetrindole 
tetrindole hydrochloride 
tetrindole mesylate 
Thioperamide  
thymoquinone  
tideglusib  
tolcapone  
toloxatone  
tramadol  
tramadol hydrochloride 
trans-rhaponticin +   
tranylcypromine  
tranylcypromine hydrochloride 
trazodone +   
trazodone hydrochloride 
triapine  
trimipramine +   
trimipramine maleate 
trofinetide 
Trolox 
tropisetron  
tropisetron hydrochloride 
ulotaront 
uridine triacetate 
valproic acid +   
venlafaxine +   
vilazodone 
vilazodone hydrochloride 
vortioxetine  
vortioxetine hydrobromide 
WIN 55212-2  
xyloketal B 
Z-DEVD-FMK 
zuranolone 

Synonyms
Exact Synonyms: 3,5-dimethyladamantan-1-amine
Related Synonyms: 1-Amino-3,5-dimethyladamantane ;   3,5-Dimethyl-1-adamantanamine ;   3,5-Dimethyl-1-aminoadamantane ;   3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine ;   Formula=C12H21N ;   InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3 ;   InChIKey=BUGYDGFZZOZRHP-UHFFFAOYSA-N ;   SMILES=CC12CC3CC(C)(C1)CC(N)(C3)C2 ;   memantina ;   memantinum
Alternate IDs: CHEBI:34832
Xrefs: CAS:19982-08-2 ;   DrugBank:DB01043 ;   Drug_Central:1679 ;   KEGG:C13736 ;   KEGG:D08174 ;   LINCS:LSM-5154
Xref Mesh: MESH:D008559
Xrefs: PMID:20104942 ;   PMID:21953515 ;   PMID:21955815 ;   PMID:22030128 ;   PMID:22134197 ;   PMID:22245025 ;   PMID:22248638 ;   PMID:22290557 ;   PMID:22297273 ;   PMID:22300835 ;   PMID:22311362 ;   PMID:22327556 ;   PMID:22329473 ;   PMID:22392787 ;   PMID:22414570 ;   PMID:22425751 ;   Patent:US2011282100 ;   Reaxys:2075983 ;   Wikipedia:Memantine
Cyclic Relationships: is_conjugate_base_of CHEBI:64325

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