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Gene: Prpf19 (pre-mRNA processing factor 19) Mus musculus
Symbol: Prpf19
Name: pre-mRNA processing factor 19
Description: Predicted to have identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including inner cell mass cell proliferation; positive regulation of mRNA splicing, via spliceosome; and regulation of neurogenesis. Localizes to cytoplasm; lipid droplet; and nucleus. Predicted to colocalize with DNA replication factor A complex. Is expressed in several structures, including extraembryonic component and genitourinary system. Orthologous to human PRPF19 (pre-mRNA processing factor 19); PARTICIPATES IN spliceosome pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 1H-pyrazole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA617263; AL024362; D19Wsu55e; NMP200; nuclear matrix protein 200; nuclear matrix protein SNEV; pre-mRNA-processing factor 19; Prp19; prp19 beta; PRP19/PSO4 homolog; PRP19/PSO4 pre-mRNA processing factor 19 homolog; PSO4; RING-type E3 ubiquitin transferase PRP19; senescence evasion factor; Snev
Homo sapiens (human) : PRPF19 (pre-mRNA processing factor 19)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Prpf19 (pre-mRNA processing factor 19)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prpf19 (pre-mRNA processing factor 19)
Pan paniscus (bonobo/pygmy chimpanzee) : PRPF19 (pre-mRNA processing factor 19)
Canis lupus familiaris (dog) : PRPF19 (pre-mRNA processing factor 19)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prpf19 (pre-mRNA processing factor 19)
Sus scrofa (pig) : PRPF19 (pre-mRNA processing factor 19)
Chlorocebus sabaeus (African green monkey) : PRPF19 (pre-mRNA processing factor 19)
Heterocephalus glaber (naked mole-rat) : Prpf19 (pre-mRNA processing factor 19)
more info ...
Related Pseudogenes: Gm7701  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1910,895,231 - 10,909,559 (+)EnsemblGRCm38mm10GRCm38
GRCm381910,895,231 - 10,909,559 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371910,969,782 - 10,980,022 (+)NCBIGRCm37mm9NCBIm37
MGSCv361910,962,337 - 10,972,577 (+)NCBImm8
Celera1911,588,283 - 11,598,524 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map197.33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Prpf19
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732635
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.