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Gene: Arl3 (ADP-ribosylation factor-like 3) Mus musculus
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Symbol: Arl3
Name: ADP-ribosylation factor-like 3
Description: Exhibits several functions, including GTPase activating protein binding activity; magnesium ion binding activity; and purine ribonucleoside binding activity. Involved in several processes, including Golgi to plasma membrane transport; intraciliary transport; and protein localization to ciliary membrane. Localizes to the axoneme; ciliary basal body; and ciliary transition zone. Used to study autosomal recessive polycystic kidney disease and retinitis pigmentosa 2. Human ortholog(s) of this gene implicated in Joubert syndrome and retinitis pigmentosa. Is expressed in central nervous system; hippocampus; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human ARL3 (ADP ribosylation factor like GTPase 3); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ADP-ribosylation factor-like protein 3; ADP-ribosylation-like 3
Orthologs:
Homo sapiens (human) : ARL3 (ADP ribosylation factor like GTPase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Arl3 (ADP ribosylation factor like GTPase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arl3 (ADP ribosylation factor like GTPase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ARL3 (ADP ribosylation factor like GTPase 3)
Canis lupus familiaris (dog) : ARL3 (ADP ribosylation factor like GTPase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arl3 (ADP ribosylation factor like GTPase 3)
Sus scrofa (pig) : ARL3 (ADP ribosylation factor like GTPase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381946,531,109 - 46,573,182 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371946,605,599 - 46,647,575 (-)NCBIGRCm37mm9NCBIm37
MGSCv361946,584,420 - 46,626,396 (-)NCBImm8
Celera1947,294,795 - 47,342,296 (-)NCBICelera
Cytogenetic Map19 C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Arl3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737247
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.