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ONTOLOGY REPORT - ANNOTATIONS


Term:diphenhydramine
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Accession:CHEBI:4636 term browser browse the term
Definition:An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
Synonyms:exact_synonym: 2-(diphenylmethoxy)-N,N-dimethylethanamine
 related_synonym: 2-(benzhydryloxy)-N,N-dimethylethylamine;   2-diphenylmethoxy-N,N-demthylethanamine;   Formula=C17H21NO;   InChI=1S/C17H21NO/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,17H,13-14H2,1-2H3;   InChIKey=ZZVUWRFHKOJYTH-UHFFFAOYSA-N;   N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine;   O-benzhydryldimethylaminoethanol;   SMILES=CN(C)CCOC(c1ccccc1)c1ccccc1;   alpha-(2-dimethylaminoethoxy)diphenylmethane;   beta-dimethylaminoethanol diphenylmethyl ether;   beta-dimethylaminoethyl benzhydryl ether;   difenhidramina;   diphenhydraminum
 xref: Beilstein:1914136 "Beilstein";   CAS:58-73-1 "ChemIDplus";   CAS:58-73-1 "NIST Chemistry WebBook";   DrugBank:DB01075;   HMDB:HMDB0001927;   KEGG:C14015;   KEGG:D00300;   KEGG:D02419;   LINCS:LSM-5581
 xref_mesh: MESH:D004155
 xref: PDBeChem:2PM;   Patent:US2421714;   Patent:US2427878;   VSDB:2973;   Wikipedia:Diphenhydramine


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diphenhydramine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg5 autophagy related 5 JBrowse link 20 49,301,783 49,393,147 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:6480464
G Gnai1 G protein subunit alpha i1 JBrowse link 4 13,405,136 13,486,866 RGD:6480464
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:6480464
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:6480464
G Slc22a1 solute carrier family 22 member 1 JBrowse link 1 48,273,639 48,300,645 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Slc22a3 solute carrier family 22 member 3 JBrowse link 1 48,433,079 48,521,261 RGD:6480464
G Slc22a5 solute carrier family 22 member 5 JBrowse link 10 39,201,101 39,228,090 RGD:6480464
dimenhydrinate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            anti-allergic agent 3776
              diphenhydramine 15
                dimenhydrinate 2
                diphenhydramine hydrochloride 0
                diphenhydramine salicylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        tertiary amino compound 8521
                                          diphenhydramine 15
                                            dimenhydrinate 2
                                            diphenhydramine hydrochloride 0
                                            diphenhydramine salicylate 0
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