Lrrc59 (leucine rich repeat containing 59)

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Gene: Lrrc59 (leucine rich repeat containing 59) Mus musculus

Analyze

Symbol:

Lrrc59

Name:

leucine rich repeat containing 59

RGD ID:

1332550

MGI Page

MGI

Description:

Predicted to be located in endoplasmic reticulum and mitochondrial nucleoid. Is expressed in several structures, including central nervous system and neural retina. Orthologous to human LRRC59 (leucine rich repeat containing 59).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

AA959742; C78668; leucine-rich repeat-containing protein 59; RP23-290B5.2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LRRC59 (leucine rich repeat containing 59)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Lrrc59 (leucine rich repeat containing 59)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lrrc59 (leucine rich repeat containing 59)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LRRC59 (leucine rich repeat containing 59)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LRRC59 (leucine rich repeat containing 59)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lrrc59 (leucine rich repeat containing 59)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LRRC59 (leucine rich repeat containing 59)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LRRC59 (leucine rich repeat containing 59)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lrrc59 (leucine rich repeat containing 59)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Lrrc59 (leucine rich repeat containing 59)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	LRRC59 (leucine rich repeat containing 59)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	lrrc59 (leucine rich repeat containing 59)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid\|ZFIN)
Caenorhabditis elegans (roundworm):	F56A8.3	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector)
Drosophila melanogaster (fruit fly):	CG3408	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	lrrc59	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	94,520,603 - 94,536,049 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	94,520,593 - 94,536,042 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	94,629,777 - 94,645,223 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	94,629,767 - 94,645,216 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	94,491,138 - 94,506,530 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	94,445,914 - 94,461,306 (+)	NCBI		MGSCv36	mm8
Celera	11	104,247,327 - 104,262,759 (+)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	58.9	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

glioblastoma (ISO)

hepatocellular carcinoma (ISO)

hereditary breast ovarian cancer syndrome (ISO)

lung non-small cell carcinoma (ISO)

Lymphatic Metastasis (ISO)

osteogenesis imperfecta type 1 (ISO)

Ovarian Neoplasms (ISO)

trichodontoosseous syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

1,2-dichloroethane (EXP)

1,2-dimethylhydrazine (EXP)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,6-tribromophenol (ISO)

2,4,6-trinitrotoluene (ISO)

2,4-dinitrotoluene (ISO)

2,6-dinitrotoluene (ISO)

2-bromohexadecanoic acid (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxynon-2-enal (ISO)

6-propyl-2-thiouracil (ISO)

7,12-dimethyltetraphene (EXP)

acrylamide (ISO)

amitrole (ISO)

antirheumatic drug (ISO)

arsenous acid (ISO)

bisphenol A (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

Brodifacoum (ISO)

buspirone (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (EXP)

CGP 52608 (ISO)

chlorpyrifos (EXP)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) chloride (ISO)

CU-O LINKAGE (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

dioxygen (EXP)

doxorubicin (ISO)

endosulfan (ISO)

enzyme inhibitor (ISO)

epoxiconazole (EXP)

ethanol (EXP)

fenthion (EXP)

fipronil (ISO)

flutamide (ISO)

folic acid (EXP)

formaldehyde (ISO)

FR900359 (ISO)

furan (ISO)

glafenine (ISO)

indometacin (ISO)

inulin (EXP)

ivermectin (ISO)

lead diacetate (ISO)

methimazole (ISO)

methylisothiazolinone (ISO)

methylparaben (ISO)

N-nitrosodiethylamine (ISO)

nefazodone (ISO)

nickel atom (ISO)

ozone (EXP)

paracetamol (EXP,ISO)

paraquat (ISO)

perfluorohexanesulfonic acid (EXP)

perfluorooctane-1-sulfonic acid (EXP)

phenobarbital (ISO)

pirinixic acid (EXP)

pregnenolone 16alpha-carbonitrile (ISO)

propiconazole (EXP)

SB 431542 (ISO)

senecionine (EXP)

silicon dioxide (EXP)

sodium arsenite (ISO)

sodium fluoride (EXP)

sulfadimethoxine (ISO)

testosterone (EXP)

tetrachloromethane (EXP,ISO)

thapsigargin (ISO)

thioacetamide (ISO)

thiram (ISO)

titanium dioxide (EXP)

tolcapone (ISO)

trichloroethene (EXP)

trimellitic anhydride (EXP)

triphenyl phosphate (ISO)

valproic acid (EXP,ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

endoplasmic reticulum (ISO)

endoplasmic reticulum membrane (IEA)

mitochondrial nucleoid (IEA,ISO)

nuclear envelope (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Electronic Transfer of Homolog Data	MGD and Homologene mouse data transfer
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:10725249	PMID:11042159	PMID:11076861	PMID:11125038	PMID:11217851	PMID:12466851	PMID:12477932	PMID:12904583	PMID:14610273	PMID:15226823	PMID:15489334
PMID:15782199	PMID:16141072	PMID:16141073	PMID:21677750	PMID:21873635	PMID:23665500	PMID:27160897	PMID:30550785	PMID:30713523	PMID:32325033	PMID:32554809	PMID:36417873
PMID:37142655

Genomics

Comparative Map Data

Lrrc59
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	94,520,603 - 94,536,049 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	94,520,593 - 94,536,042 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	94,629,777 - 94,645,223 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	94,629,767 - 94,645,216 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	94,491,138 - 94,506,530 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	94,445,914 - 94,461,306 (+)	NCBI		MGSCv36	mm8
Celera	11	104,247,327 - 104,262,759 (+)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	58.9	NCBI

LRRC59
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	50,381,238 - 50,397,523 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	50,375,059 - 50,397,523 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	48,458,599 - 48,474,884 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	45,813,598 - 45,829,831 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	44,919,883 - 44,936,207 (-)	NCBI		Celera
Cytogenetic Map	17	q21.33	NCBI
HuRef	17	43,826,456 - 43,842,733 (-)	NCBI		HuRef
CHM1_1	17	48,522,442 - 48,538,780 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	51,248,223 - 51,264,511 (-)	NCBI		T2T-CHM13v2.0

Lrrc59
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	80,069,162 - 80,083,820 (+)	NCBI		GRCr8
mRatBN7.2	10	79,572,295 - 79,586,953 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	79,572,317 - 79,602,533 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	84,177,036 - 84,191,592 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	83,675,116 - 83,689,668 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	79,190,586 - 79,205,104 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	82,352,390 - 82,367,047 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	82,352,390 - 82,367,047 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	82,171,007 - 82,185,664 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	83,264,264 - 83,278,807 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	83,278,633 - 83,293,177 (+)	NCBI
Celera	10	78,359,448 - 78,373,949 (+)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

Lrrc59
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	11,315,725 - 11,332,394 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	11,316,139 - 11,328,107 (+)	NCBI	ChiLan1.0	ChiLan1.0

LRRC59
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	66,573,079 - 66,589,868 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	71,380,168 - 71,400,156 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	44,475,661 - 44,492,021 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	49,349,738 - 49,366,039 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	49,349,738 - 49,366,039 (-)	Ensembl	panpan1.1		panPan2

LRRC59
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	26,350,300 - 26,364,021 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	26,351,734 - 26,364,082 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	25,743,300 - 25,757,075 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	27,144,701 - 27,158,485 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	27,141,195 - 27,158,487 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	25,912,485 - 25,926,266 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	26,171,174 - 26,184,936 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	26,301,200 - 26,314,976 (-)	NCBI		UU_Cfam_GSD_1.0

Lrrc59
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	25,767,919 - 25,778,543 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	11,296,530 - 11,310,946 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936490	11,296,590 - 11,308,379 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LRRC59
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	26,677,226 - 26,694,279 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	26,678,207 - 26,694,277 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	26,587,660 - 26,603,718 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LRRC59
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	42,931,726 - 42,949,281 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	42,932,549 - 42,947,655 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	13,648,003 - 13,665,008 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lrrc59
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624795	6,316,472 - 6,329,166 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624795	6,317,677 - 6,328,554 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Lrrc59
559 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	886
Count of miRNA genes:	513
Interacting mature miRNAs:	626
Transcripts:	ENSMUST00000021239, ENSMUST00000138782
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
27226783	Tibl5_m	tibia length 5, 5 week (mouse)					11	68190826	101890826	Mouse
1302034	Pkccl_m	protein kinase C content in lungs (mouse)			Not determined		11	91604608	121973369	Mouse
1300628	Lgth6_m	body length 6 (mouse)			Not determined		11	66733420	100733652	Mouse
4141367	Inf1_m	acute ozone induced inflammation (mouse)			Not determined			44630038	113058009	Mouse
1558812	Rafar_m	retinoic acid induced forelimb autopod reduction (mouse)			Not determined		11	70691198	104691366	Mouse
1300766	Skull16_m	skull morphology 16 (mouse)			Not determined		11	81574481	115574636	Mouse
1301404	Sbmd4_m	spinal bone mineral density 4 (mouse)			Not determined		11	72019649	106019734	Mouse
4142121	Tmc1m2_m	Tmc1 modifier 2 (mouse)			Not determined		11	56864027	114157957	Mouse
27226758	Femd3_m	femur midshaft diameter 3, 5 week (mouse)					11	80890826	101890826	Mouse
14747003	Mancz9_m	mandible centroid size 9 (mouse)					11	85844911	119844911	Mouse
1301640	Lore4_m	loss of righting induced by ethanol 4 (mouse)			Not determined		11	79156009	107616472	Mouse
10412288	Carg4_m	Candida albicans resistance gene 4 (mouse)			Not determined		11	81810267	115810267	Mouse
11251723	Ewc5_m	ethanol withdrawal and consumption 5 (mouse)					11	89869251	121973369	Mouse
1301681	Sle13_m	systematic lupus erythematosus susceptibility 13 (mouse)			Not determined		11	70691198	104691366	Mouse
1300784	Prdt3_m	prion disease incubation time 3 (mouse)			Not determined		11	66733420	100733652	Mouse
4141339	Nilac2_m	nicotine induced locomotor activity 2 (mouse)			Not determined		11	70691198	104691366	Mouse
10413882	Moe1_m	modifier of epilepsy 1 (mouse)					11	77770978	111771099	Mouse
11039501	Ltpr6a_m	Leishmania tropica response 6a (mouse)					11	64830336	98830473	Mouse
11039502	Ltpr6b_m	Leishmania tropica response 6b (mouse)					11	64830336	98830473	Mouse
4141465	Dbm2_m	diabetes modifier 2 (mouse)			Not determined			94437183	118022724	Mouse
13208558	Lgth12_m	body length 12 (mouse)					11	3950000	94890826	Mouse
10045617	Heal26_m	wound healing/regeneration 26 (mouse)			Not determined		11	92939373	112544554	Mouse
10045616	Heal25_m	wound healing/regeneration 25 (mouse)			Not determined		11	77437183	111437322	Mouse
1357631	Motr1_m	modifier of tubby retinal degeneration 1 (mouse)			Not determined		11	87691198	103274115	Mouse
1301310	Tmevd5_m	Theiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)			Not determined		11	72726125	106726289	Mouse
11039515	Ltpr6_m	Leishmania tropica response 6 (mouse)					11	64830336	98830473	Mouse
4142348	Pstc2_m	periosteal circumference 2 (mouse)			Not determined		11	72818615	106818733	Mouse
1301414	Heal10_m	wound healing/regeneration 10 (mouse)			Not determined		11	77437183	111437322	Mouse
15092049	Wsigrme3_m	week six growth rate, maternal effect 3 (mouse)					11	84877324	96629512	Mouse
1300651	Pcyts3_m	plasmacytoma susceptibility 3 (mouse)			Not determined		11	70691198	104691366	Mouse
1301546	Pcir2_m	periosteal circumference 2 (mouse)			Not determined		11	66733420	100733652	Mouse
1300649	Crhq1_m	compensatory renal hypertrophy QTL 1 (mouse)			Not determined		11	81574481	115574636	Mouse
27226789	Feml16_m	femur length 16, 10 week (mouse)					11	87490826	121873369	Mouse
14746970	Manh71_m	mandible shape 71 (mouse)					11	79416257	113416257	Mouse
15092057	Lgrme3_m	late growth rate, maternal effect 3 (mouse)					11	84877324	96629512	Mouse
10043865	T2dm5sa_m	type 2 diabetes mellitus 5 in SMXA RI mice (mouse)			Not determined		11	79813759	104502698	Mouse
39128214	Lwq20_m	liver weight QTL 20 (mouse)					11	12268637	118022724	Mouse
10043866	Adip19_m	adiposity 19 (mouse)			Not determined		11	72818615	106818733	Mouse
1301072	Eae22_m	experimental allergic encephalomyelitis 22 (mouse)			Not determined		11	82377698	116377820	Mouse
10412246	Dfs2_m	dental fluorosis suseptibility 2 (mouse)			Not determined		11	21807364	95881231	Mouse
4141939	Pregq2_m	pregnancy QTL 2 (mouse)			Not determined		11	94063779	118022724	Mouse
11038695	Par8_m	pulmonary adenoma resistance 8 (mouse)					11	77063779	111063918	Mouse
1357766	Si5lq6_m	serum IGFBP-5 level QTL 6 (mouse)			Not determined		11	66733420	100733652	Mouse
1301319	Dautb4_m	dopamine uptake transporter binding 4 (mouse)			Not determined		11	62156005	96156153	Mouse
1301833	Tbbmd5_m	total body bone mineral density 5 (mouse)			Not determined		11	66733420	100733652	Mouse
1301491	Abbp4_m	A/J and C57BL/6 blood pressure 4 (mouse)			Not determined		11	88699588	99081597	Mouse
15014785	Mvlq1_m	macrovesicular liver lesion QTL 1 (mouse)					11	86608320	120608320	Mouse
4141012	Femwf6_m	femur work to failure 6 (mouse)			Not determined			66733420	100733652	Mouse
15039374	Adip29_m	adiposity 29 (mouse)					11	86608320	120608320	Mouse
1301095	El6_m	epilepsy 6 (mouse)			Not determined		11	93229183	121973369	Mouse
27226731	Tibmd4_m	tibia midshaft diameter 4, 10 week (mouse)					11	94190826	118890826	Mouse
27226730	Tibmd1_m	tibia midshaft diameter 1, 5 week (mouse)					11	62590826	109390826	Mouse
15039376	Bw42_m	body weight QTL 42 (mouse)					11	86608320	120608320	Mouse
1558753	Ath19_m	atherosclerosis 19 (mouse)			Not determined		11	91604608	121973369	Mouse
4141894	Nidd6k_m	Nidd6 on KK-A (mouse)			Not determined			19124204	96897826	Mouse
1300847	Par1_m	pulmonary adenoma resistance 1 (mouse)			Not determined		11	94063779	96167421	Mouse
10044007	Hbnr14_m	Heligmosomoides bakeri nematode resistance 14 (mouse)			Not determined		11	87502600	121502698	Mouse
1302124	Eae7_m	susceptibility to experimental allergic encephalomyelitis 7 (mouse)			Not determined		11	77573873	99377820	Mouse
13524529	Bodwtq10_m	body wweight QTL 10 (mouse)					11	90679512	97699512	Mouse

Markers in Region

AA959742

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	11	94,644,883 - 94,645,011	UniSTS	GRCm38
MGSCv37	11	94,506,197 - 94,506,325	UniSTS	GRCm37
Celera	11	104,262,426 - 104,262,554	UniSTS
Cytogenetic Map	11	D	UniSTS
Whitehead/MRC_RH	1	1107.18	UniSTS

RH126417

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	11	94,640,779 - 94,641,012	UniSTS	GRCm38
MGSCv37	11	94,502,093 - 94,502,326	UniSTS	GRCm37
Celera	11	104,258,286 - 104,258,525	UniSTS
Cytogenetic Map	11	D	UniSTS
Whitehead/MRC_RH	11	1249.32	UniSTS

AI596487

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	11	94,629,369 - 94,629,454	UniSTS	GRCm38
MGSCv37	11	94,490,683 - 94,490,768	UniSTS	GRCm37
Celera	11	104,246,872 - 104,246,957	UniSTS
Celera	11	104,244,624 - 104,244,709	UniSTS
Cytogenetic Map	11	D	UniSTS
Whitehead/MRC_RH	11	1257.45	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AK053450	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK150916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK159374	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK159552	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK166576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK167604	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK169250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK169390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK183165	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK186256	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK188560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK196953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK201979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK206116	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK210679	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK212315	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK212762	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK212896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK213336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK214600	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK214924	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL645764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC006877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC066172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466556	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CX203638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000021239 ⟹ ENSMUSP00000021239

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	94,520,593 - 94,536,042 (+)	Ensembl
GRCm38.p6 Ensembl	11	94,629,767 - 94,645,216 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000138782

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	94,520,640 - 94,526,078 (+)	Ensembl
GRCm38.p6 Ensembl	11	94,629,814 - 94,635,252 (+)	Ensembl

RefSeq Acc Id:

NM_133807 ⟹ NP_598568

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	94,520,603 - 94,536,049 (+)	NCBI
GRCm38	11	94,629,777 - 94,645,223 (+)	NCBI
MGSCv37	11	94,491,138 - 94,506,530 (+)	RGD
Celera	11	104,247,327 - 104,262,759 (+)	RGD
cM Map	11		ENTREZGENE

Sequence:

show sequence

AGTGGTCGTCGTCGCGGCGGCACCGGTGGGAGCGGGGCCCTGGGCTGGGAGTGCGGCGGGCGAG
CGGACGGGCGGCGGAGGCCTCGCAGCGGCGGCGGAGGCGACGGCGGCTTAAGGCGCAGGCGTGG
TCCGTTGGGTGTGAGTCCGCCGAGCCCACGAGCGGCCCCTCATCCCTCTCTCCTGCCCGTCGGA
AACCGGGAGCCAGGGACCCGCTTAGCCGGCGTCATCATGACCAAGGCCGGTAGCAAGGGCGGGA
ACCTCCGCGACAAGCTGGACGGCAATGAGCTGGACCTGAGCCTCAGCGACCTGAATGAAGTCCC
CGTCAAGGAGCTGGCTGCACTTCCCAAGGCTACGGTATTGGATCTGTCCTGCAATAAACTGAGT
ACTCTTCCGTCGGATTTCTGTGGCCTCACACACCTGGTAAAGCTGGACCTCAGCAAGAACAAGC
TGCAGCAGCTACCCGCAGACTTTGGCCGCCTGGTTAACCTTCAGCATTTGGATCTCCTCAACAA
CAGGCTGGTCACCCTGCCTGTCAGCTTTGCCCAGCTCAAGAATCTGAAGTGGCTGGATCTGAAG
GACAATCCCCTGGACCCTGTCCTGGCCAAGGTGGCAGGTGATTGCTTGGATGAGAAGCAATGTA
AGCAGTGTGCAAACAAGGTGTTACAGCACATGAAGGCCGTGCAGGCAGATCAGGAACGAGAGCG
GCAGCGCCGGCTGGAAGTGGAGCGAGAGGCAGAGAAGAAGCGTGAGGCCAAGCAGCAAGCTAAG
GAAGCGAAGGAGCGCGAGCTGCGGAAGCGGGAGAAGGCGGAGGAGAAGGAGCGCCGGCGGAAGG
AGTATGACGCTCAGAAGGCGTCCAAGCGGGAGCAAGAGAAGAAGCCTAAGAAAGAGGCAAACCA
GGCCCCGAAATCGAAGTCTGGCTCTCGTCCTCGCAAGCCACCACCCCGAAAACACACTCGCTCC
TGGGCTGTGCTGAAGGTGTTGCTGTTGCTCCTGCTGCTGTGTGTAGCAGGAGGGCTGGTTGTAT
GCCGGGTGACAGGGCTGCACCAGCAGCCCCTCTGCACCAGCGTGAACACCATCTACGACAATGC
GGTCCAGGGCCTGCGTCATCATGAGATCCTCCAGTGGGTCCTGCAAACCGACTCCCAGCAGTGA
GCTCACCCTCAGCACCCGCTGCCTCCCAGCCTTGGAGCTTGGATTCCTATGGAATTGGGTTCTG
CTGGACACAACCTCTTTTTAGCGTCAGACCTACCTGCCATCATCACATGGCTGCTGGTGGTACT
TGAGATCTCCCCTTTGTAGGACTTCTGTTCCATAGTCAGGGTTCCCTGGTGGAATGAGGAGAAA
TGGAGAGGGGGGAGGAAGAGTTACCTGCATGCCTAAAGGAGTAGGCTTAGGGGTGGGGAGAGAG
AAGGCATAGGCTTTTCTAGTTATACAAAGCTGTGTAAGGCAAGGTTCCTTTCTACTAAATGGTC
AGCTGTCACTACATTTATACTTTTGTATGTCATAAACCCTTTCTTTCATTCCTCCCTGGGTAAC
CAGGACAATCGGAGGGCAGTGTGTTACTGGGATTAGAGGACTAGCAATACTGGGTAACCCAGCC
TAAGCTGGGAAGGTGACGTAATACGTTTCTTTAAAGATTCAGTCAGTCAAGCAGTTTAGCAATA
TCCAAAATGTCTGGCTGTTTGGTCCAGTGTCACATGTTGAGGCAGGAGGTGCCGTCTCATCCAT
GACTTGCCAGCAGTGTTCAGGCTAGTCTGAGGCACAACCAGGCTCTCATTCCAGTTTTCCTCCT
TCCCTTTATGTCATTCGACCTCCTATATAATACCCAAGAGGATGAACTCACACCAGAGTTGTCT
CAGCTAAAGCGAATCTTTCATAACAGTCTTACCACCCACAAATAGATCTCATATCATCAGGGTC
CTGGGAAACTTAACTCCTGTGGAATTTTGCCTCAACTTTTAAATGGCTTCCACAAAATGGCAGC
AGGCCGGGTTCCTTGCCTCAGTTTTAGAGCATTAACTCCCGAATGGCCTGGAAGCAGAGGGAAC
TCTGCAAAGCCGTACTGTGGCTGCTCCACTAGCACTCGGTGTGATGAAATACCTCAAAGGCAAC
CTAGAAACTTGACTTCATGGAAGCAGGTTTAGAGTTGATTCTGGACCTGTAACAGAAGGGAAGG
AAGGAAGAGAACAGTGGGAGTCAAAGGGAAACAAAGTCACATGGTGGCGCTGCAGAGTGATACA
TAACTAAACATTAGCACAACCAGGGCAGAGCCGCCCACCTCCCTGCTGCTACAAGAAAGCATTC
TCCCCTTTCCCAGTCTCTTCACAACAGCTGCATGAAGGGATCAGAAACAACTGTGTCTCGGTGC
TTACTTGCTAAAAACTCCCATTTGCAAGCTCCCTAGAGGAGCAAGGACCTGTCATAGTTCAGCA
GTGTAGCCCTAGTGGCCCATCTGGATAGGTCTGCCATTCAAAACTGTCCTGACACTGGAAGAAA
GGCCTTGGATTTTTCCTCCCCAGACAGTTCTGCCATGTAGGCCCACACCTCCTCAGCATCACCT
CCTCAGCATCACTACACGCTCCTTTAGTCTTCCTCCAAGCTCCACAGCCATTGGTACAAAGGCT
TTATTGAGACAAAATACATACTACATACATATGGTGACATCATGAAAACAGGAGTCAGCCTCAT
CATAGCTCCCTAGCTGGTTGAGGCAGCTCAGTGGCTGGGCGTAGTCAAGCCAACCCGCAGGCAA
GAGTTCACTCTGACTTCGAGATTTGATGCTTATTTCTTGGATTTCTACAATTATTAAATCCATG
TCTGAGTGGTCTGCCTTTAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_598568	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH06877	(Get FASTA)	NCBI Sequence Viewer
	AAH66172	(Get FASTA)	NCBI Sequence Viewer
	BAC35390	(Get FASTA)	NCBI Sequence Viewer
	BAE29954	(Get FASTA)	NCBI Sequence Viewer
	BAE35030	(Get FASTA)	NCBI Sequence Viewer
	BAE35177	(Get FASTA)	NCBI Sequence Viewer
	BAE38865	(Get FASTA)	NCBI Sequence Viewer
	BAE39660	(Get FASTA)	NCBI Sequence Viewer
	BAE41014	(Get FASTA)	NCBI Sequence Viewer
	BAE41137	(Get FASTA)	NCBI Sequence Viewer
	EDL15935	(Get FASTA)	NCBI Sequence Viewer
	EDL15936	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000021239
	ENSMUSP00000021239.7
GenBank Protein	Q922Q8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_598568 ⟸ NM_133807

- UniProtKB:

Q3TWT9 (UniProtKB/Swiss-Prot), Q3TLC7 (UniProtKB/Swiss-Prot), Q3TJ35 (UniProtKB/Swiss-Prot), Q3TX86 (UniProtKB/Swiss-Prot), Q922Q8 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHL
VKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKVA
GDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEVEREAEKKREAKQQAKEAKERELRKREK
AEEKERRRKEYDAQKASKREQEKKPKKEANQAPKSKSGSRPRKPPPRKHTRSWAVLKVLLLLLL
LCVAGGLVVCRVTGLHQQPLCTSVNTIYDNAVQGLRHHEILQWVLQTDSQQ

hide sequence

Ensembl Acc Id:

ENSMUSP00000021239 ⟸ ENSMUST00000021239

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q922Q8-F1-model_v2	AlphaFold	Q922Q8	1-307	view protein structure

Promoters

RGD ID:

6821206

Promoter ID:

MM_KWN:9277

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day1, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

ENSMUST00000107767, OTTMUST00000004069, OTTMUST00000004070

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	94,490,911 - 94,491,487 (+)	MPROMDB

RGD ID:

8676290

Promoter ID:

EPDNEW_M16142

Type:

initiation region

Name:

Lrrc59_1

Description:

Mus musculus leucine rich repeat containing 59 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	11	94,629,777 - 94,629,837	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2138133	AgrOrtholog
Ensembl Genes	ENSMUSG00000020869	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000021239	ENTREZGENE
	ENSMUST00000021239.7	UniProtKB/Swiss-Prot
Gene3D-CATH	3.80.10.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Leu-rich_rpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LRR_domain-containing	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:98238	UniProtKB/Swiss-Prot
MGD	MGI:2138133	ENTREZGENE
NCBI Gene	98238	ENTREZGENE
PANTHER	NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR48051	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	LRR_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LRR_8	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Lrrc59	PhenoGen
PRINTS	LEURICHRPT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	LRR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	LRR_TYP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	L domain-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	LRC59_MOUSE	UniProtKB/Swiss-Prot
	Q3TF84_MOUSE	UniProtKB/TrEMBL
	Q3TJ35	ENTREZGENE
	Q3TLC7	ENTREZGENE
	Q3TWT9	ENTREZGENE
	Q3TX86	ENTREZGENE
	Q3UBL0_MOUSE	UniProtKB/TrEMBL
	Q922Q8	ENTREZGENE
UniProt Secondary	Q3TJ35	UniProtKB/Swiss-Prot
	Q3TLC7	UniProtKB/Swiss-Prot
	Q3TWT9	UniProtKB/Swiss-Prot
	Q3TX86	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD