Lrrc59 (leucine rich repeat containing 59)

Gene: Lrrc59 (leucine rich repeat containing 59) Chinchilla lanigera

Analyze

Symbol:

Lrrc59

Name:

leucine rich repeat containing 59

RGD ID:

8710613

Description:

ASSOCIATED WITH genetic disease (ortholog); glioblastoma (ortholog); hepatocellular carcinoma (ortholog); FOUND IN endoplasmic reticulum (ortholog); mitochondrial nucleoid (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

leucine-rich repeat-containing protein 59

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	11,315,725 - 11,332,394 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	11,316,139 - 11,328,107 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

glioblastoma (ISO)

hepatocellular carcinoma (ISO)

lung non-small cell carcinoma (ISO)

Lymphatic Metastasis (ISO)

osteogenesis imperfecta type 1 (ISO)

Ovarian Neoplasms (ISO)

trichodontoosseous syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

endoplasmic reticulum (ISO)

mitochondrial nucleoid (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Lrrc59
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	11,315,725 - 11,332,394 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	11,316,139 - 11,328,107 (+)	NCBI	ChiLan1.0	ChiLan1.0

LRRC59
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	50,381,238 - 50,397,523 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	50,375,059 - 50,397,523 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	48,458,599 - 48,474,884 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	45,813,598 - 45,829,831 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	44,919,883 - 44,936,207 (-)	NCBI		Celera
Cytogenetic Map	17	q21.33	NCBI
HuRef	17	43,826,456 - 43,842,733 (-)	NCBI		HuRef
CHM1_1	17	48,522,442 - 48,538,780 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	51,248,223 - 51,264,511 (-)	NCBI		T2T-CHM13v2.0

Lrrc59
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	94,520,603 - 94,536,049 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	94,520,593 - 94,536,042 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	94,629,777 - 94,645,223 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	94,629,767 - 94,645,216 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	94,491,138 - 94,506,530 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	94,445,914 - 94,461,306 (+)	NCBI		MGSCv36	mm8
Celera	11	104,247,327 - 104,262,759 (+)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	58.9	NCBI

Lrrc59
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	80,069,162 - 80,083,820 (+)	NCBI		GRCr8
mRatBN7.2	10	79,572,295 - 79,586,953 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	79,572,317 - 79,602,533 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	84,177,036 - 84,191,592 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	83,675,116 - 83,689,668 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	79,190,586 - 79,205,104 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	82,352,390 - 82,367,047 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	82,352,390 - 82,367,047 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	82,171,007 - 82,185,664 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	83,264,264 - 83,278,807 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	83,278,633 - 83,293,177 (+)	NCBI
Celera	10	78,359,448 - 78,373,949 (+)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

LRRC59
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	66,573,079 - 66,589,868 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	71,380,168 - 71,400,156 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	44,475,661 - 44,492,021 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	49,349,738 - 49,366,039 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	49,349,738 - 49,366,039 (-)	Ensembl	panpan1.1		panPan2

LRRC59
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	26,350,300 - 26,364,021 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	26,351,734 - 26,364,082 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	25,743,300 - 25,757,075 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	27,144,701 - 27,158,485 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	27,141,195 - 27,158,487 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	25,912,485 - 25,926,266 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	26,171,174 - 26,184,936 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	26,301,200 - 26,314,976 (-)	NCBI		UU_Cfam_GSD_1.0

Lrrc59
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	25,767,919 - 25,778,543 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	11,296,530 - 11,310,946 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936490	11,296,590 - 11,308,379 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LRRC59
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	26,677,226 - 26,694,279 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	26,678,207 - 26,694,277 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	26,587,660 - 26,603,718 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LRRC59
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	42,931,726 - 42,949,281 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	42,932,549 - 42,947,655 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	13,648,003 - 13,665,008 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lrrc59
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624795	6,316,472 - 6,329,166 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624795	6,317,677 - 6,328,554 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005394173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01043349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01007688	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000018586 ⟹ ENSCLAP00000018405

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955451	11,315,725 - 11,332,394 (+)	Ensembl

RefSeq Acc Id:

XM_005394173 ⟹ XP_005394230

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955451	11,316,139 - 11,328,107 (+)	NCBI

Sequence:

show sequence

GGAAGGTGACGTGGACACGGAAGTGGCCGTCGCCGCGGCGGCACCGGTGGGAGCGGGGCGCGGG
ACTCAGAGTGCGGCCGACGGGCGGGCGGCAGCGACCTCGCAGCGGCGGCGGCGGCGAAGCGCAG
GCGTTGTCCGTTGGGTCCTGATCCGCTGAGCCGACGACGGCTCCCGAGCCCCGCACGCGCGTCC
GTCGGAGCCCGGAGTCGGGGCCCGCTCAGCCGGCGTCGCCATGACCAAGGCGGGCAGTAAGGGC
GGGAACCTCCGCGACAAGCTGGACGGTAACGAGCTGGACCTGAGCCTCAGCGACCTGAACGAGG
TCCCCGTCAAGGAGCTGGCTGCGCTTCCAAAGGCCACCATACTGGATCTGTCCTGCAATAAACT
AAGCACTCTGCCGTCGGATTTCTGTGGCCTCACACACCTGGTGAAGTTGGACCTCAGCAAGAAT
AAGCTGCAGCAGCTGCCGGCAGATTTTGGCCGCCTGGTCAACCTCCAGCACCTGGATCTCCTCA
ACAACAGGCTGGTTACTCTGCCCGTCAGCTTTGCGCAGCTCAAGAACCTGAAGTGGCTGGACCT
GAAGGACAACCCCCTGGACCCTGTCCTGGCCAAAGTAGCAGGCGACTGCTTGGATGAGAAGCAG
TGTAAGCAATGTGCGAACAAGGTGTTACAGCACATGAAGGCCATGCAGGCGGACCAGGAGCGAG
AGAGGCAGCGGCGGCTGGAAGTGGAGCGAGAGGTGGAGAAGAAGCGGGAGGCCAAGCAGCGAGC
AAAGGAAGCTCAGGAGCGGGAGCTGCGGAAGCGGGAGAAGGCGGAGGAGAAGGAGCGGCGGCGG
AAGGAGTATGACGCCCTCAAGGCCTCCAAGAAGGAGCAGGAGAAGAAGCCCAAGAAGGAAGCAA
ATCAGGCCCCGAAGTCCAAGTCTGGCTCCCGCCCCCGCAAGCCACCACCCCGGAAGCAGGCTCG
GTCCTGGGTCGTGCTGAAGCTGCTGCTGCTGCTGCTGCTGCTGTGTGTGGGGGGCGGGCTGGTC
GCGTGTCGCCTGACGGCGCTGCAGCAGCAGCCGCTCTGCGCCAGCGTGAACACCGTCTATGACA
ACGCCGTGCAGGGGCTGCGGCGCCACGAGATCCTCCAGTGGGTCCTGCAGGCCGACTCTCAGCA
GTGAGCCTGGCCCGGGCCCTGTTGCCTCCCAGCCCCGGAGCTTGGATTCCTATGGAATTGGGTT
CTGCTGGACACAACCTCTTTTTAGCGTCACACCTACCCGCCGTCATCCGCGGCTGCCAACTGGT
ACTGGGGGCCCCCTCGGGTGGGACTCCGTGTCTCATCAGGGCTCCCCGGTAGGGTGAGGAGGAT
CGGGAGGTGGGAGGGAGTGACCTGCATGCCTAAAGGAGTAGGCTTCTCGGTGGGGAGAGAAAAC
AGCCTTTTCTAGTTACTACAGAAGCTGTCTAAAGGCAAGGCTCGTTTCTACTAAATGGTCAGCT
GTCACTACGTTGATA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005394230	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000018405
	ENSCLAP00000018405.1

RefSeq Acc Id:

XP_005394230 ⟸ XM_005394173

- UniProtKB:

A0A8C2VR38 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALPKATILDLSCNKLSTLPSDFCGLTHL
VKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKVA
GDCLDEKQCKQCANKVLQHMKAMQADQERERQRRLEVEREVEKKREAKQRAKEAQERELRKREK
AEEKERRRKEYDALKASKKEQEKKPKKEANQAPKSKSGSRPRKPPPRKQARSWVVLKLLLLLLL
LCVGGGLVACRLTALQQQPLCASVNTVYDNAVQGLRRHEILQWVLQADSQQ

hide sequence

RefSeq Acc Id:

ENSCLAP00000018405 ⟸ ENSCLAT00000018586

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000012618	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000018586	ENTREZGENE
	ENSCLAT00000018586.1	UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	Leu-rich_rpt	UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Lrrc59	ENTREZGENE
PANTHER	NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE-RELATED	UniProtKB/TrEMBL
	PTHR48051	UniProtKB/TrEMBL
Pfam	LRR_1	UniProtKB/TrEMBL
	LRR_8	UniProtKB/TrEMBL
PRINTS	LEURICHRPT	UniProtKB/TrEMBL
PROSITE	LRR	UniProtKB/TrEMBL
SMART	LRR_TYP	UniProtKB/TrEMBL
Superfamily-SCOP	L domain-like	UniProtKB/TrEMBL
UniProt	A0A8C2VR38	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD