Ltc4s (leukotriene C4 synthase) - Rat Genome Database

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Gene: Ltc4s (leukotriene C4 synthase) Mus musculus
Analyze
Symbol: Ltc4s
Name: leukotriene C4 synthase
RGD ID: 733492
MGI Page MGI
Description: Enables leukotriene-C4 synthase activity and lipid binding activity. Acts upstream of or within leukotriene metabolic process. Predicted to be located in endoplasmic reticulum membrane and nuclear outer membrane. Predicted to be active in endoplasmic reticulum and nuclear envelope. Orthologous to human LTC4S (leukotriene C4 synthase).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: glutathione S-transferase LTC4; leukotriene-C(4) synthase; LTC4 synthase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,127,288 - 50,129,378 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,127,288 - 50,129,443 (-)EnsemblGRCm39 Ensembl
GRCm381150,236,461 - 50,238,532 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,236,461 - 50,238,616 (-)EnsemblGRCm38mm10GRCm38
MGSCv371150,049,974 - 50,051,973 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361150,079,895 - 50,081,894 (-)NCBIMGSCv36mm8
Celera1154,797,050 - 54,799,049 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1130.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Human bronchial epithelial cells express an active and inducible biosynthetic pathway for leukotrienes B4 and C4. Jame AJ, etal., Clin Exp Allergy. 2007 Jun;37(6):880-92.
2. Enhanced expressions and activations of leukotriene C4 synthesis enzymes in D-galactosamine/lipopolysaccharide-induced rat fulminant hepatic failure model. Ma KF, etal., World J Gastroenterol. 2008 May 7;14(17):2748-56.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Leukotriene synthases and the receptors induced by peripheral nerve injury in the spinal cord contribute to the generation of neuropathic pain. Okubo M, etal., Glia. 2010 Apr;58(5):599-610.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Renal leukotriene C4 synthase: characterization, partial purification and alterations in experimental glomerulonephritis. Petric R, etal., Biochim Biophys Acta. 1995 Jan 20;1254(2):207-15.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8706658   PMID:9342232   PMID:11319240   PMID:11748223   PMID:12023288   PMID:12477932   PMID:12878209   PMID:14681479   PMID:14970333   PMID:15730873   PMID:15905575   PMID:16407308  
PMID:16547282   PMID:16567388   PMID:16602821   PMID:16920908   PMID:19124755   PMID:19416808   PMID:20219953   PMID:21267068   PMID:21307302   PMID:21357742   PMID:21873635   PMID:22416124  
PMID:23002438   PMID:23624557   PMID:24810165   PMID:26663781   PMID:27185938   PMID:27365393   PMID:28011865   PMID:29282304   PMID:30291131   PMID:30649890   PMID:31135881   PMID:34932383  
PMID:37437602  


Genomics

Comparative Map Data
Ltc4s
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,127,288 - 50,129,378 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,127,288 - 50,129,443 (-)EnsemblGRCm39 Ensembl
GRCm381150,236,461 - 50,238,532 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,236,461 - 50,238,616 (-)EnsemblGRCm38mm10GRCm38
MGSCv371150,049,974 - 50,051,973 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361150,079,895 - 50,081,894 (-)NCBIMGSCv36mm8
Celera1154,797,050 - 54,799,049 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1130.4NCBI
LTC4S
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385179,793,986 - 179,796,647 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5179,793,980 - 179,796,647 (+)EnsemblGRCh38hg38GRCh38
GRCh375179,220,987 - 179,223,648 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365179,153,592 - 179,156,119 (+)NCBINCBI36Build 36hg18NCBI36
Build 345179,153,591 - 179,156,119NCBI
Celera5174,846,142 - 174,848,669 (+)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5173,947,161 - 173,949,688 (+)NCBIHuRef
CHM1_15178,653,394 - 178,655,921 (+)NCBICHM1_1
T2T-CHM13v2.05180,349,182 - 180,351,843 (+)NCBIT2T-CHM13v2.0
Ltc4s
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81035,060,002 - 35,066,466 (-)NCBIGRCr8
mRatBN7.21034,560,476 - 34,562,790 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1034,560,360 - 34,562,651 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1039,235,902 - 39,237,857 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0107,775,154 - 7,777,109 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01034,229,574 - 34,231,529 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01035,736,486 - 35,743,088 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1035,737,664 - 35,739,625 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01035,498,195 - 35,506,088 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,786,877 - 35,788,838 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11035,787,925 - 35,789,881 (-)NCBI
Celera1033,909,805 - 33,911,766 (-)NCBICelera
Cytogenetic Map10q22NCBI
Ltc4s
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955408788,856 - 791,505 (-)NCBIChiLan1.0ChiLan1.0
LTC4S
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24174,735,060 - 174,739,519 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15172,874,599 - 172,879,058 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05174,946,346 - 174,950,805 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15182,256,113 - 182,261,003 (+)NCBIpanpan1.1PanPan1.1panPan2
LTC4S
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1111,893,927 - 1,897,028 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl111,894,380 - 1,897,752 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha112,012,534 - 2,020,224 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0111,863,608 - 1,871,298 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl111,867,307 - 1,871,411 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1111,835,205 - 1,842,895 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0111,914,372 - 1,922,062 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0112,154,596 - 2,162,286 (-)NCBIUU_Cfam_GSD_1.0
Ltc4s
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213119,765,712 - 119,768,688 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936739975,493 - 978,482 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936739975,494 - 978,426 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LTC4S
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl278,799,449 - 78,802,285 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1278,799,446 - 78,802,281 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2280,365,497 - 80,368,339 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LTC4S
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12381,523,784 - 81,526,297 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2381,523,775 - 81,526,179 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607512,900,551 - 12,903,368 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ltc4s
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473342,670,632 - 42,672,846 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473342,668,963 - 42,673,385 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ltc4s
108 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:543
Count of miRNA genes:289
Interacting mature miRNAs:319
Transcripts:ENSMUST00000101265, ENSMUST00000102772, ENSMUST00000125555
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112719805750636094Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112719805750636094Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112719805750636094Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112719805750636094Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112719805750636094Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114277262654081064Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
13452402Hipmt3_mhippocampal morphometry trait 3 (mouse)114797732550277325Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000101265   ⟹   ENSMUSP00000098823
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,127,296 - 50,129,298 (-)Ensembl
GRCm38.p6 Ensembl1150,236,469 - 50,238,471 (-)Ensembl
RefSeq Acc Id: ENSMUST00000102772   ⟹   ENSMUSP00000099833
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,127,299 - 50,129,359 (-)Ensembl
GRCm38.p6 Ensembl1150,236,472 - 50,238,532 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125555   ⟹   ENSMUSP00000121584
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,127,299 - 50,129,443 (-)Ensembl
GRCm38.p6 Ensembl1150,236,472 - 50,238,616 (-)Ensembl
RefSeq Acc Id: ENSMUST00000221081
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,127,311 - 50,128,461 (-)Ensembl
GRCm38.p6 Ensembl1150,236,484 - 50,237,634 (-)Ensembl
RefSeq Acc Id: ENSMUST00000221391
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,127,288 - 50,128,384 (-)Ensembl
GRCm38.p6 Ensembl1150,236,461 - 50,237,557 (-)Ensembl
RefSeq Acc Id: ENSMUST00000221525   ⟹   ENSMUSP00000152524
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,127,299 - 50,129,322 (-)Ensembl
GRCm38.p6 Ensembl1150,236,472 - 50,238,495 (-)Ensembl
RefSeq Acc Id: ENSMUST00000222076
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,127,299 - 50,129,343 (-)Ensembl
GRCm38.p6 Ensembl1150,236,472 - 50,238,516 (-)Ensembl
RefSeq Acc Id: NM_001313968   ⟹   NP_001300897
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391150,127,288 - 50,129,359 (-)NCBI
GRCm381150,236,461 - 50,238,532 (-)NCBI
Sequence:
RefSeq Acc Id: NM_008521   ⟹   NP_032547
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391150,127,288 - 50,129,359 (-)NCBI
GRCm381150,236,461 - 50,238,532 (-)NCBI
MGSCv371150,049,974 - 50,051,973 (-)RGD
Celera1154,797,050 - 54,799,049 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_132732
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391150,127,288 - 50,129,359 (-)NCBI
GRCm381150,236,461 - 50,238,532 (-)NCBI
Sequence:
RefSeq Acc Id: NR_132733
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391150,127,288 - 50,129,359 (-)NCBI
GRCm381150,236,461 - 50,238,532 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156365   ⟹   XP_036012258
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391150,127,288 - 50,129,378 (-)NCBI
Sequence:
RefSeq Acc Id: NP_032547   ⟸   NM_008521
- Peptide Label: isoform 1
- UniProtKB: Q5SVR7 (UniProtKB/Swiss-Prot),   Q9QVS1 (UniProtKB/Swiss-Prot),   Q60860 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001300897   ⟸   NM_001313968
- Peptide Label: isoform 2
- UniProtKB: Q8K355 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000121584   ⟸   ENSMUST00000125555
RefSeq Acc Id: ENSMUSP00000098823   ⟸   ENSMUST00000101265
RefSeq Acc Id: ENSMUSP00000152524   ⟸   ENSMUST00000221525
RefSeq Acc Id: ENSMUSP00000099833   ⟸   ENSMUST00000102772
RefSeq Acc Id: XP_036012258   ⟸   XM_036156365
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q60860-F1-model_v2 AlphaFold Q60860 1-150 view protein structure

Promoters
RGD ID:6821211
Promoter ID:MM_KWN:7235
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   3T3L1_Day6,   Lung
Transcripts:ENSMUST00000101265,   OTTMUST00000012402,   OTTMUST00000012403
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361150,052,026 - 50,052,737 (-)MPROMDB
RGD ID:8674504
Promoter ID:EPDNEW_M15283
Type:initiation region
Name:Ltc4s_1
Description:Mus musculus leukotriene C4 synthase , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381150,238,513 - 50,238,573EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107498 AgrOrtholog
Ensembl Genes ENSMUSG00000020377 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000101265 ENTREZGENE
  ENSMUST00000101265.9 UniProtKB/TrEMBL
  ENSMUST00000102772 ENTREZGENE
  ENSMUST00000102772.4 UniProtKB/Swiss-Prot
  ENSMUST00000125555 ENTREZGENE
  ENSMUST00000125555.2 UniProtKB/TrEMBL
  ENSMUST00000221525 ENTREZGENE
  ENSMUST00000221525.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 5_LipOase_AP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FLAP/GST2/LTC4S_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAPEG-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Membr-assoc_MAPEG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17001 UniProtKB/Swiss-Prot
MGD MGI:107498 ENTREZGENE
NCBI Gene 17001 ENTREZGENE
PANTHER LEUKOTRIENE C4 SYNTHASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MICROSOMAL GLUTATHIONE S-TRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MAPEG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB LTC4S RGD
PhenoGen Ltc4s PhenoGen
PRINTS 5LPOXGNASEAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FLAP_GST2_LTC4S UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF161084 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1Y7VLL2_MOUSE UniProtKB/TrEMBL
  LTC4S_MOUSE UniProtKB/Swiss-Prot
  Q5SVR6_MOUSE UniProtKB/TrEMBL
  Q5SVR7 ENTREZGENE
  Q60860 ENTREZGENE
  Q8K355 ENTREZGENE, UniProtKB/TrEMBL
  Q9QVS1 ENTREZGENE
UniProt Secondary Q5SVR7 UniProtKB/Swiss-Prot
  Q9QVS1 UniProtKB/Swiss-Prot