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Gene: Tgfb1 (transforming growth factor, beta 1) Mus musculus
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Symbol: Tgfb1
Name: transforming growth factor, beta 1
RGD ID: 69096
Description: Exhibits protein serine/threonine kinase activator activity and transforming growth factor beta receptor binding activity. Involved in several processes, including animal organ development; regulation of cellular protein localization; and regulation of gene expression. Localizes to extracellular matrix and extracellular space. Predicted to colocalize with microvillus. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; heart; and skin. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; aphthous stomatitis; artery disease (multiple); bone disease (multiple); and lung disease (multiple). Orthologous to human TGFB1 (transforming growth factor beta 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: regulatory protein; TGF-beta; TGF-beta 1; TGF-beta-1; TGF-beta1; Tgfb; Tgfb-1; TGFbeta; TGFbeta1; transforming growth factor beta-1; transforming growth factor beta-1 proprotein; transforming growth factor-beta 1
Orthologs:
Homo sapiens (human) : TGFB1 (transforming growth factor beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgfb1 (transforming growth factor, beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfb1 (transforming growth factor beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFB1 (transforming growth factor beta 1)
Canis lupus familiaris (dog) : B9D2 (B9 domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfb1 (transforming growth factor beta 1)
Sus scrofa (pig) : TGFB1 (transforming growth factor beta 1)
Chlorocebus sabaeus (African green monkey) : TGFB1 (transforming growth factor beta 1)
Heterocephalus glaber (naked mole-rat) : Tgfb1 (transforming growth factor beta 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl725,687,002 - 25,705,077 (+)EnsemblGRCm38mm10GRCm38
GRCm38725,687,002 - 25,705,077 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37726,472,021 - 26,490,015 (+)NCBIGRCm37mm9NCBIm37
MGSCv36725,395,762 - 25,413,756 (+)NCBImm8
Celera720,295,914 - 20,313,908 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model