Hspg2 (perlecan (heparan sulfate proteoglycan 2)) - Rat Genome Database

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Gene: Hspg2 (perlecan (heparan sulfate proteoglycan 2)) Mus musculus
Analyze
Symbol: Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
RGD ID: 1558001
MGI Page MGI
Description: Enables protease binding activity. Involved in receptor-mediated endocytosis. Acts upstream of or within several processes, including cardiac muscle tissue development; extracellular matrix organization; and skeletal system development. Located in basement membrane. Is expressed in several structures, including alimentary system; cardiovascular system; early conceptus; genitourinary system; and nervous system. Used to study Schwartz-Jampel syndrome 1; Silverman-Handmaker type dyssegmental dysplasia; dextro-looped transposition of the great arteries; and thanatophoric dysplasia. Human ortholog(s) of this gene implicated in Schwartz-Jampel syndrome 1; Silverman-Handmaker type dyssegmental dysplasia; and osteochondrodysplasia. Orthologous to human HSPG2 (heparan sulfate proteoglycan 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI852380; basement membrane-specific heparan sulfate proteoglycan core protein; HSPG; p; Pcn; per; Plc
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394137,196,062 - 137,297,941 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4137,196,080 - 137,297,941 (+)EnsemblGRCm39 Ensembl
GRCm384137,468,751 - 137,570,630 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4137,468,769 - 137,570,630 (+)EnsemblGRCm38mm10GRCm38
MGSCv374137,024,718 - 137,126,545 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364137,024,724 - 137,126,545 (+)NCBIMGSCv36mm8
Celera4135,720,332 - 135,778,896 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map469.93NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (ISO)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
7,12-dimethyltetraphene  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
aspartame  (EXP)
atrazine  (ISO)
Azoxymethane  (EXP)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP)
buta-1,3-diene  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cantharidin  (EXP)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
chromium(6+)  (EXP)
clobetasol  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
Cuprizon  (ISO)
cypermethrin  (EXP)
dextran sulfate  (EXP)
dicrotophos  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
ethanol  (EXP)
fenamidone  (EXP)
folic acid  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glycidyl methacrylate  (ISO)
glyphosate  (ISO)
haloperidol  (EXP)
indometacin  (ISO)
inulin  (EXP)
isoprenaline  (EXP)
ivermectin  (ISO)
methamphetamine  (EXP)
methotrexate  (ISO)
methoxychlor  (ISO)
miconazole  (EXP)
monosodium L-glutamate  (EXP)
nickel sulfate  (ISO)
obeticholic acid  (ISO)
ozone  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
pentachlorophenol  (EXP)
perfluorohexanesulfonic acid  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
potassium chromate  (ISO)
quercetin  (ISO)
reserpine  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
Soman  (ISO)
streptozocin  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal action potential  (IAGP)
abnormal aortic valve morphology  (IAGP)
abnormal ascending aorta and coronary artery attachment  (IAGP)
abnormal axon morphology  (IAGP)
abnormal basement membrane morphology  (IAGP)
abnormal behavior  (IAGP)
abnormal bone marrow cavity morphology  (IAGP)
abnormal bone marrow morphology  (IAGP)
abnormal bone ossification  (IAGP)
abnormal bone structure  (IAGP)
abnormal brain morphology  (IAGP)
abnormal cardiac outflow tract development  (IAGP)
abnormal cardinal vein morphology  (IAGP)
abnormal cartilage development  (IAGP)
abnormal cartilage morphology  (IAGP)
abnormal cell physiology  (IAGP)
abnormal chest morphology  (IAGP)
abnormal chondrocyte morphology  (IAGP)
abnormal conotruncus septation  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal endochondral bone ossification  (IAGP)
abnormal endplate potential  (IAGP)
abnormal ethmoid bone morphology  (IAGP)
abnormal femur head morphology  (IAGP)
abnormal femur neck morphology  (IAGP)
abnormal forelimb morphology  (IAGP)
abnormal gait  (IAGP)
abnormal heart and great artery attachment  (IAGP)
abnormal hindlimb morphology  (IAGP)
abnormal humerus morphology  (IAGP)
abnormal inner ear development  (IAGP)
abnormal internode morphology  (IAGP)
abnormal intervertebral disk development  (IAGP)
abnormal joint morphology  (IAGP)
abnormal lens development  (IAGP)
abnormal locomotor coordination  (IAGP)
abnormal long bone epiphyseal plate morphology  (IAGP)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal long bone epiphysis morphology  (IAGP)
abnormal long bone hypertrophic chondrocyte zone  (IAGP)
abnormal long bone metaphysis morphology  (IAGP)
abnormal long bone morphology  (IAGP)
abnormal middle ear development  (IAGP)
abnormal miniature endplate potential  (IAGP)
abnormal muscle electrophysiology  (IAGP)
abnormal muscle morphology  (IAGP)
abnormal myelin sheath morphology  (IAGP)
abnormal myocardium compact layer morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal neuromuscular synapse morphology  (IAGP)
abnormal node of Ranvier morphology  (IAGP)
abnormal occipital bone morphology  (IAGP)
abnormal osteoclast morphology  (IAGP)
abnormal paranode morphology  (IAGP)
abnormal pelvic girdle bone morphology  (IAGP)
abnormal pericardium morphology  (IAGP)
abnormal pulmonary valve morphology  (IAGP)
abnormal radial glial cell endfoot morphology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal semilunar valve morphology  (IAGP)
abnormal skeletal muscle fiber morphology  (IAGP)
abnormal skeletal muscle fiber type ratio  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal sphenoid bone morphology  (IAGP)
abnormal spine curvature  (IAGP)
abnormal sternum morphology  (IAGP)
abnormal telencephalon morphology  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal vertebral body morphology  (IAGP)
abnormal vertebral column morphology  (IAGP)
absent conotruncal ridges  (IAGP)
absent frontal bone  (IAGP)
absent neurocranium  (IAGP)
absent parietal bone  (IAGP)
aneurysm  (IAGP)
bowed humerus  (IAGP)
centrally nucleated skeletal muscle fibers  (IAGP)
chondrodystrophy  (IAGP)
cleft palate  (IAGP)
conotruncal ridge hyperplasia  (IAGP)
decreased body length  (IAGP)
decreased body weight  (IAGP)
decreased bone mineralization  (IAGP)
decreased chondrocyte proliferation  (IAGP)
decreased cranium height  (IAGP)
decreased embryo size  (IAGP)
decreased length of long bones  (IAGP)
delayed bone ossification  (IAGP)
delayed eyelid opening  (IAGP)
demyelination  (IAGP)
dilated liver sinusoidal space  (IAGP)
disorganized long bone epiphyseal plate  (IAGP)
disproportionate dwarf  (IAGP)
domed cranium  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enlarged vertebral body  (IAGP)
exencephaly  (IAGP)
flat face  (IAGP)
hemopericardium  (IAGP)
hemorrhage  (IAGP)
impaired basement membrane formation  (IAGP)
increased compact bone thickness  (IAGP)
increased diameter of humerus  (IAGP)
increased diameter of long bones  (IAGP)
increased osteoclast cell number  (IAGP)
increased Schwann cell number  (IAGP)
increased variability of skeletal muscle fiber size  (IAGP)
increased width of hypertrophic chondrocyte zone  (IAGP)
intracranial hemorrhage  (IAGP)
irregular heartbeat  (IAGP)
lung hemorrhage  (IAGP)
microphthalmia  (IAGP)
osteoarthritis  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
respiratory failure  (IAGP)
short femur  (IAGP)
short femur neck  (IAGP)
short humerus  (IAGP)
short limbs  (IAGP)
short mandible  (IAGP)
short nasal bone  (IAGP)
short snout  (IAGP)
skeletal muscle hyperplasia  (IAGP)
skin hemorrhage  (IAGP)
transposition of great arteries  (IAGP)
wide cranial sutures  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Heparan sulfate proteoglycan synthesis and its expression are decreased in the retina of diabetic rats. Bollineni JS, etal., Curr Eye Res. 1997 Feb;16(2):127-30.
2. Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule. Gotsman I, etal., Circulation. 2006 Nov 7;114(19):2047-55. Epub 2006 Oct 23.
3. Coarctation induces alterations in basement membranes in the cardiovascular system. Lipke DW, etal., Hypertension. 1993 Nov;22(5):743-53.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Perlecan, the major proteoglycan of basement membranes, is altered in patients with Schwartz-Jampel syndrome (chondrodystrophic myotonia). Nicole S, etal., Nat Genet. 2000 Dec;26(4):480-3.
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. SHh activity and localization is regulated by perlecan. Palma V, etal., Biol Res. 2011;44(1):63-7. doi: 10.4067/S0716-97602011000100008. Epub 2011 May 11.
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Reduced perlecan expression and accumulation in human carotid atherosclerotic lesions. Tran PK, etal., Atherosclerosis. 2007 Feb;190(2):264-70. Epub 2006 Apr 18.
15. High-glucose-induced structural changes in the heparan sulfate proteoglycan, perlecan, of cultured human aortic endothelial cells. Vogl-Willis CA and Edwards IJ, Biochim Biophys Acta. 2004 Apr 7;1672(1):36-45.
Additional References at PubMed
PMID:1383086   PMID:1685141   PMID:1686572   PMID:1744087   PMID:2972708   PMID:3159725   PMID:3665768   PMID:7649154   PMID:7670489   PMID:7945186   PMID:8027524   PMID:8231112  
PMID:8433569   PMID:8889548   PMID:8914972   PMID:8951060   PMID:9142982   PMID:9337134   PMID:9486530   PMID:9524110   PMID:9788974   PMID:9915576   PMID:10349636   PMID:10352025  
PMID:10433923   PMID:10544250   PMID:10545953   PMID:10579711   PMID:10579729   PMID:10600481   PMID:10918573   PMID:11042159   PMID:11076861   PMID:11084655   PMID:11217851   PMID:11259264  
PMID:11279527   PMID:11357198   PMID:11400157   PMID:11427896   PMID:11564885   PMID:11574465   PMID:11771669   PMID:11787818   PMID:11802174   PMID:11973346   PMID:12015298   PMID:12122449  
PMID:12142349   PMID:12192060   PMID:12242711   PMID:12243745   PMID:12477932   PMID:12514129   PMID:12520002   PMID:12571105   PMID:12588956   PMID:12682087   PMID:12761845   PMID:12814946  
PMID:12818570   PMID:12904583   PMID:14610273   PMID:14656929   PMID:14691545   PMID:14739157   PMID:15186747   PMID:15214943   PMID:15258195   PMID:15280392   PMID:15377789   PMID:15381701  
PMID:15657057   PMID:15668394   PMID:15878328   PMID:15895400   PMID:15928325   PMID:16024816   PMID:16098969   PMID:16100707   PMID:16141072   PMID:16141073   PMID:16219760   PMID:16407285  
PMID:16439479   PMID:16498405   PMID:16554364   PMID:16683015   PMID:16750824   PMID:16785251   PMID:16804890   PMID:16873583   PMID:16880404   PMID:16956876   PMID:17023412   PMID:17095659  
PMID:17213231   PMID:17411441   PMID:17525255   PMID:17608588   PMID:17767158   PMID:17948866   PMID:17959718   PMID:17967808   PMID:17997086   PMID:18024432   PMID:18040286   PMID:18267097  
PMID:18314316   PMID:18356808   PMID:18448648   PMID:18559345   PMID:18570250   PMID:18586242   PMID:18589009   PMID:18596265   PMID:18647752   PMID:18676816   PMID:18694874   PMID:18757743  
PMID:18799693   PMID:18816447   PMID:19056886   PMID:19367640   PMID:19373938   PMID:19587446   PMID:19783738   PMID:19789387   PMID:19924818   PMID:20072119   PMID:20089971   PMID:20114047  
PMID:20237296   PMID:20514525   PMID:20541011   PMID:20684947   PMID:20814969   PMID:20858856   PMID:20970343   PMID:21067603   PMID:21085708   PMID:21289070   PMID:21289173   PMID:21350012  
PMID:21452199   PMID:21677750   PMID:21747167   PMID:21839920   PMID:21850672   PMID:21873635   PMID:21903675   PMID:21924961   PMID:22072575   PMID:22083510   PMID:22159717   PMID:22222602  
PMID:22244880   PMID:22266517   PMID:22274697   PMID:22281059   PMID:22421594   PMID:22449950   PMID:22472609   PMID:22613833   PMID:22753893   PMID:22767514   PMID:22952693   PMID:23104139  
PMID:23217742   PMID:23281850   PMID:23320101   PMID:23339896   PMID:23493297   PMID:23509775   PMID:23509972   PMID:23658023   PMID:23722005   PMID:24006456   PMID:24058167   PMID:24115222  
PMID:24457600   PMID:24559672   PMID:24798737   PMID:24858854   PMID:24983472   PMID:25042397   PMID:25158168   PMID:25179606   PMID:25646087   PMID:25808553   PMID:26024086   PMID:26056142  
PMID:26116392   PMID:26319110   PMID:26428891   PMID:26465331   PMID:26636652   PMID:26993635   PMID:27098652   PMID:27238423   PMID:27377666   PMID:27578148   PMID:27613501   PMID:27829154  
PMID:27856617   PMID:28011632   PMID:28071719   PMID:28634551   PMID:28714851   PMID:28760865   PMID:29743679   PMID:29773865   PMID:30042881   PMID:30089653   PMID:30149005   PMID:30228991  
PMID:30456378   PMID:30550785   PMID:30563944   PMID:30814516   PMID:30883226   PMID:30993430   PMID:31112136   PMID:31541017   PMID:31600777   PMID:31715337   PMID:32013135   PMID:32201365  
PMID:32205445   PMID:32220631   PMID:32325033   PMID:32381549   PMID:32514132   PMID:32523119   PMID:32673396   PMID:32913205   PMID:33144400   PMID:33875569   PMID:34132262   PMID:34433968  
PMID:34653670   PMID:35008739   PMID:36335435   PMID:36792666   PMID:37174615   PMID:37408198   PMID:37936982   PMID:38051393   PMID:38103869   PMID:38246333   PMID:38303699   PMID:38545339  
PMID:39217171  


Genomics

Comparative Map Data
Hspg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394137,196,062 - 137,297,941 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4137,196,080 - 137,297,941 (+)EnsemblGRCm39 Ensembl
GRCm384137,468,751 - 137,570,630 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4137,468,769 - 137,570,630 (+)EnsemblGRCm38mm10GRCm38
MGSCv374137,024,718 - 137,126,545 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364137,024,724 - 137,126,545 (+)NCBIMGSCv36mm8
Celera4135,720,332 - 135,778,896 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map469.93NCBI
HSPG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38121,822,244 - 21,937,310 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl121,822,244 - 21,937,310 (-)EnsemblGRCh38hg38GRCh38
GRCh37122,148,737 - 22,263,803 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,021,324 - 22,136,337 (-)NCBINCBI36Build 36hg18NCBI36
Build 34121,894,545 - 22,009,053NCBI
Celera120,471,674 - 20,545,742 (-)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef120,392,206 - 20,466,222 (-)NCBIHuRef
CHM1_1122,261,185 - 22,335,234 (-)NCBICHM1_1
T2T-CHM13v2.0121,646,052 - 21,761,123 (-)NCBIT2T-CHM13v2.0
Hspg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85154,960,818 - 155,061,971 (+)NCBIGRCr8
mRatBN7.25149,677,437 - 149,778,594 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5149,677,476 - 149,778,594 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05155,812,096 - 155,913,751 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5155,812,105 - 155,885,829 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.05159,568,612 - 159,669,759 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5148,073,391 - 148,174,691 (+)NCBICelera
Cytogenetic Map5q36NCBI
Hspg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554522,057,326 - 2,120,280 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554522,056,428 - 2,141,937 (-)NCBIChiLan1.0ChiLan1.0
HSPG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21205,002,944 - 205,117,920 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11204,114,809 - 204,229,767 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0121,014,951 - 21,129,937 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1121,979,504 - 22,053,395 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl121,979,504 - 22,053,400 (-)Ensemblpanpan1.1panPan2
HSPG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1277,263,534 - 77,366,558 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl277,301,858 - 77,367,724 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha273,772,098 - 73,871,430 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0277,826,669 - 77,926,300 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl277,860,347 - 77,926,289 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,646,666 - 74,745,989 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,656,010 - 75,755,977 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0276,659,904 - 76,759,494 (+)NCBIUU_Cfam_GSD_1.0
Hspg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505841,582,855 - 41,654,168 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364747,408,518 - 7,467,851 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364747,407,622 - 7,478,950 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSPG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl679,849,698 - 79,958,334 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1679,849,691 - 79,958,283 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2673,882,694 - 73,947,389 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSPG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120110,693,858 - 110,809,467 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20110,693,854 - 110,809,466 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660335,486,539 - 5,602,022 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hspg2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247646,640,087 - 6,708,130 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247646,639,152 - 6,736,161 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hspg2
7167 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1269
Count of miRNA genes:394
Interacting mature miRNAs:461
Transcripts:ENSMUST00000030547, ENSMUST00000155648, ENSMUST00000171332
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
12050091Shm2_msperm head morphology 2 (mouse)4136876000138342753Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
4142082Psds2_mpsoriasis-like skin disease severity 2 (mouse)Not determined4133154678137617995Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
4141154Nba1_mNew Zealand Black autoimmunity 1 (mouse)Not determined131650724140879275Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
4141779Ssrq8_mstress response QTL 8 (mouse)Not determined136876000137617995Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse

Markers in Region
Hspg2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv374137,126,375 - 137,126,507UniSTSGRCm37
Celera4135,778,726 - 135,778,858UniSTS
Cytogenetic Map4D3UniSTS
cM Map471.4UniSTS
cM Map471.4UniSTS
AI852380  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384137,570,486 - 137,570,569UniSTSGRCm38
MGSCv374137,126,401 - 137,126,484UniSTSGRCm37
Celera4135,778,752 - 135,778,835UniSTS
Cytogenetic Map4D3UniSTS
cM Map471.4UniSTS
Whitehead/MRC_RH41813.35UniSTS
Whitehead/MRC_RH41812.62UniSTS
Hspg2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384137,570,460 - 137,570,592UniSTSGRCm38
MGSCv374137,126,375 - 137,126,507UniSTSGRCm37
Celera4135,778,726 - 135,778,858UniSTS
Cytogenetic Map4D3UniSTS
cM Map471.4UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_008305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK147294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC036291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC108381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX000694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX323857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA326802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB525885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD349187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN694897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN696673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR450281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ113652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ266428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M83997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000030547   ⟹   ENSMUSP00000030547
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4137,196,080 - 137,297,941 (+)Ensembl
GRCm38.p6 Ensembl4137,468,769 - 137,570,630 (+)Ensembl
Ensembl Acc Id: ENSMUST00000155648
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4137,296,482 - 137,297,428 (+)Ensembl
GRCm38.p6 Ensembl4137,569,171 - 137,570,117 (+)Ensembl
Ensembl Acc Id: ENSMUST00000171332   ⟹   ENSMUSP00000131316
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4137,196,114 - 137,297,940 (+)Ensembl
GRCm38.p6 Ensembl4137,468,803 - 137,570,629 (+)Ensembl
Ensembl Acc Id: ENSMUST00000238544   ⟹   ENSMUSP00000158633
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4137,249,770 - 137,256,208 (+)Ensembl
GRCm38.p6 Ensembl4137,522,459 - 137,528,897 (+)Ensembl
RefSeq Acc Id: NM_008305   ⟹   NP_032331
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,196,093 - 137,297,941 (+)NCBI
GRCm384137,468,803 - 137,570,630 (+)NCBI
MGSCv374137,024,718 - 137,126,545 (+)RGD
Celera4135,720,332 - 135,778,896 (+)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006538575   ⟹   XP_006538638
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,196,062 - 137,297,941 (+)NCBI
GRCm384137,468,751 - 137,570,630 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030253229   ⟹   XP_030109089
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,196,062 - 137,297,941 (+)NCBI
GRCm384137,468,751 - 137,570,630 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036163696   ⟹   XP_036019589
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,196,062 - 137,287,377 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032331   ⟸   NM_008305
- Peptide Label: precursor
- UniProtKB: B1B0C7 (UniProtKB/TrEMBL),   E9PZ16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006538638   ⟸   XM_006538575
- Peptide Label: isoform X2
- UniProtKB: B1B0C7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030109089   ⟸   XM_030253229
- Peptide Label: isoform X1
- UniProtKB: B1B0C7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000131316   ⟸   ENSMUST00000171332
Ensembl Acc Id: ENSMUSP00000158633   ⟸   ENSMUST00000238544
Ensembl Acc Id: ENSMUSP00000030547   ⟸   ENSMUST00000030547
RefSeq Acc Id: XP_036019589   ⟸   XM_036163696
- Peptide Label: isoform X3
- UniProtKB: B1B0C7 (UniProtKB/TrEMBL)
Protein Domains
EGF-like   Ig-like   Ig-like C2-type   Laminin EGF-like   Laminin G   Laminin G-like   Laminin IV type A   LDL-receptor class A   SEA

Promoters
RGD ID:6835483
Promoter ID:MM_KWN:40255
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_008305,   OTTMUST00000023078,   UC008VJC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364137,024,326 - 137,025,167 (+)MPROMDB
RGD ID:6835481
Promoter ID:MM_KWN:40256
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:ENSMUST00000097839
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364137,087,021 - 137,087,521 (+)MPROMDB
RGD ID:6835607
Promoter ID:MM_KWN:40257
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:UC008VJD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364137,097,186 - 137,097,686 (+)MPROMDB
RGD ID:6847816
Promoter ID:MM_ACW:36159
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4
Transcripts:HSPG2.ESEP07,   HSPG2.FSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364137,104,191 - 137,104,691 (+)MPROMDB
RGD ID:6885152
Promoter ID:EPDNEW_M6027
Type:initiation region
Name:Hspg2_1
Description:Mus musculus perlecan , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384137,468,782 - 137,468,842EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96257 AgrOrtholog
Ensembl Genes ENSMUSG00000028763 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000030547 ENTREZGENE
  ENSMUST00000030547.15 UniProtKB/TrEMBL
  ENSMUST00000171332 ENTREZGENE
  ENSMUST00000171332.2 UniProtKB/TrEMBL
  ENSMUST00000238544.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.400.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cell_Adh-Cytoskel_Orgn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin/Netrin_ECM UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_G UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_IV UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LDL_receptor-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LDLR_class-A_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LDrepeatLR_classA_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurexin-related_CASP UniProtKB/TrEMBL
  SEA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15530 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96257 ENTREZGENE
NCBI Gene 15530 ENTREZGENE
PANTHER AGRIN UniProtKB/TrEMBL
  BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN UniProtKB/TrEMBL
  CONTACTIN 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  NETRIN/LAMININ-RELATED UniProtKB/TrEMBL
  PIKACHURIN-LIKE PROTEIN UniProtKB/TrEMBL
  WRAPPER_REGA-1_KLINGON HOMOLOG UniProtKB/Swiss-Prot
Pfam EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_G_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ldl_recept_a UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hspg2 PhenoGen
PRINTS LDLRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LAMININ_IVA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LDLRA_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LDLRA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Lam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LamB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LamG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LDLa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57424 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A571BD72_MOUSE UniProtKB/TrEMBL
  B1B0C7 ENTREZGENE, UniProtKB/TrEMBL
  E9PZ16 ENTREZGENE, UniProtKB/TrEMBL
  PGBM_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q2XQV0_MOUSE UniProtKB/TrEMBL
  Q3UHH3_MOUSE UniProtKB/TrEMBL
  Q52KG8_MOUSE UniProtKB/TrEMBL
  Q5RKM8_MOUSE UniProtKB/TrEMBL