Hspg2 (heparan sulfate proteoglycan 2) - Rat Genome Database

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Gene: Hspg2 (heparan sulfate proteoglycan 2) Heterocephalus glaber
Analyze
Symbol: Hspg2
Name: heparan sulfate proteoglycan 2
RGD ID: 18922213
Description: ENCODES a protein that exhibits collagen V binding (ortholog); protease binding (ortholog); INVOLVED IN animal organ regeneration (ortholog); brain development (ortholog); cardiac muscle tissue development (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (ortholog); atrial fibrillation (ortholog); carotid artery disease (ortholog); FOUND IN basement membrane (ortholog); collagen-containing extracellular matrix (ortholog); extracellular matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: basement membrane-specific heparan sulfate proteoglycan core protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247646,640,087 - 6,708,130 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247646,639,152 - 6,736,161 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hspg2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247646,640,087 - 6,708,130 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247646,639,152 - 6,736,161 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HSPG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38121,822,244 - 21,937,310 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl121,822,244 - 21,937,310 (-)EnsemblGRCh38hg38GRCh38
GRCh37122,148,737 - 22,263,803 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,021,324 - 22,136,337 (-)NCBINCBI36Build 36hg18NCBI36
Build 34121,894,545 - 22,009,053NCBI
Celera120,471,674 - 20,545,742 (-)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef120,392,206 - 20,466,222 (-)NCBIHuRef
CHM1_1122,261,185 - 22,335,234 (-)NCBICHM1_1
T2T-CHM13v2.0121,646,052 - 21,761,123 (-)NCBIT2T-CHM13v2.0
Hspg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394137,196,062 - 137,297,941 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4137,196,080 - 137,297,941 (+)EnsemblGRCm39 Ensembl
GRCm384137,468,751 - 137,570,630 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4137,468,769 - 137,570,630 (+)EnsemblGRCm38mm10GRCm38
MGSCv374137,024,718 - 137,126,545 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364137,024,724 - 137,126,545 (+)NCBIMGSCv36mm8
Celera4135,720,332 - 135,778,896 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map469.93NCBI
Hspg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85154,960,818 - 155,061,971 (+)NCBIGRCr8
mRatBN7.25149,677,437 - 149,778,594 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5149,677,476 - 149,778,594 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05155,812,096 - 155,913,751 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5155,812,105 - 155,885,829 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.05159,568,612 - 159,669,759 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5148,073,391 - 148,174,691 (+)NCBICelera
Cytogenetic Map5q36NCBI
Hspg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554522,057,326 - 2,120,280 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554522,056,428 - 2,141,937 (-)NCBIChiLan1.0ChiLan1.0
HSPG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21205,002,944 - 205,117,920 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11204,114,809 - 204,229,767 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0121,014,951 - 21,129,937 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1121,979,504 - 22,053,395 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl121,979,504 - 22,053,400 (-)Ensemblpanpan1.1panPan2
HSPG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1277,263,534 - 77,366,558 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl277,301,858 - 77,367,724 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha273,772,098 - 73,871,430 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0277,826,669 - 77,926,300 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl277,860,347 - 77,926,289 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,646,666 - 74,745,989 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,656,010 - 75,755,977 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0276,659,904 - 76,759,494 (+)NCBIUU_Cfam_GSD_1.0
Hspg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505841,582,855 - 41,654,168 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364747,408,518 - 7,467,851 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364747,407,622 - 7,478,950 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSPG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl679,849,698 - 79,958,334 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1679,849,691 - 79,958,283 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2673,882,694 - 73,947,389 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSPG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120110,693,858 - 110,809,467 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20110,693,854 - 110,809,466 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660335,486,539 - 5,602,022 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000014947   ⟹   ENSHGLP00000014802
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247646,640,087 - 6,708,130 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000014948   ⟹   ENSHGLP00000014803
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247646,640,087 - 6,708,130 (-)Ensembl
RefSeq Acc Id: XM_013074281   ⟹   XP_012929735
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247646,639,152 - 6,736,161 (-)NCBI
RefSeq Acc Id: XM_013074282   ⟹   XP_012929736
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247646,639,152 - 6,736,161 (-)NCBI
Protein Sequences
Protein RefSeqs XP_012929735 (Get FASTA)   NCBI Sequence Viewer  
  XP_012929736 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014802
Reference Protein Sequences
RefSeq Acc Id: XP_012929736   ⟸   XM_013074282
- Peptide Label: isoform X2
- UniProtKB: G5BI06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012929735   ⟸   XM_013074281
- Peptide Label: isoform X1
- UniProtKB: G5BI06 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000014802   ⟸   ENSHGLT00000014947
RefSeq Acc Id: ENSHGLP00000014803   ⟸   ENSHGLT00000014948


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010568 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000014947 ENTREZGENE
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  Immunoglobulins UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Low-density Lipoprotein Receptor UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
  Laminin_IV UniProtKB/TrEMBL
  LDL_receptor-like_sf UniProtKB/TrEMBL
  LDLR_class-A_CS UniProtKB/TrEMBL
  LDrepeatLR_classA_rpt UniProtKB/TrEMBL
  LE_dom UniProtKB/TrEMBL
  SEA_dom UniProtKB/TrEMBL
NCBI Gene Hspg2 ENTREZGENE
PANTHER CONTACTIN 5 UniProtKB/TrEMBL
  MYOTILIN UniProtKB/TrEMBL
Pfam EGF UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  Laminin_B UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G_1 UniProtKB/TrEMBL
  Ldl_recept_a UniProtKB/TrEMBL
PRINTS LDLRECEPTOR UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
  LAMININ_IVA UniProtKB/TrEMBL
  LDLRA_1 UniProtKB/TrEMBL
  LDLRA_2 UniProtKB/TrEMBL
  SEA UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  LamB UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  LDLa UniProtKB/TrEMBL
  SEA UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP Concanavalin A-like lectins/glucanases UniProtKB/TrEMBL
  EGF/Laminin UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
  LDL receptor-like module UniProtKB/TrEMBL
UniProt G5BI06 ENTREZGENE, UniProtKB/TrEMBL