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Gene: Abcb11 (ATP-binding cassette, sub-family B (MDR/TAP), member 11) Mus musculus
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Symbol: Abcb11
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 11
Description: Predicted to have ATPase-coupled transmembrane transporter activity; canalicular bile acid transmembrane transporter activity; and carbohydrate transmembrane transporter activity. Predicted to be involved in canalicular bile acid transport; drug export; and transmembrane transport. Localizes to the apical part of cell; intercellular canaliculus; and membrane. Human ortholog(s) of this gene implicated in benign recurrent intrahepatic cholestasis 2; intrahepatic cholestasis; liver cirrhosis; and progressive familial intrahepatic cholestasis 2. Is expressed in liver. Orthologous to human ABCB11 (ATP binding cassette subfamily B member 11).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ABC16; ATP-binding cassette sub-family B member 11; ATP-binding cassette, sub-family B, member 11; bile salt export pump; Bsep; Lith1; PFIC2; PGY4; sister of P-glycoprotein; SPGP
Orthologs:
Homo sapiens (human) : ABCB11 (ATP binding cassette subfamily B member 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Abcb11 (ATP binding cassette subfamily B member 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcb11 (ATP binding cassette subfamily B member 11)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCB11 (ATP binding cassette subfamily B member 11)
Canis lupus familiaris (dog) : ABCB11 (ATP binding cassette subfamily B member 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcb11 (ATP binding cassette subfamily B member 11)
Sus scrofa (pig) : ABCB11 (ATP binding cassette subfamily B member 11)
Chlorocebus sabaeus (green monkey) : ABCB11 (ATP binding cassette subfamily B member 11)
Heterocephalus glaber (naked mole-rat) : Abcb11 (ATP binding cassette subfamily B member 11)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl269,238,282 - 69,342,616 (-)Ensembl
GRCm38269,238,282 - 69,342,616 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37269,076,339 - 69,180,673 (-)NCBIGRCm37mm9NCBIm37
MGSCv36269,039,121 - 69,143,426 (-)NCBImm8
Celera270,904,503 - 71,008,403 (-)NCBICelera
Cytogenetic Map2 C2NCBI
cM Map239.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Abcb11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730945
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.