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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tifa | Mouse | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TIFA mRNA | CTD | PMID:36331819 | Tifa | Mouse | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of TIFA mRNA | CTD | PMID:22206623 | Tifa | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TIFA mRNA | CTD | PMID:22206623 | Tifa | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TIFA mRNA | CTD | PMID:19770486 | Tifa | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TIFA mRNA | CTD | PMID:26377647 | Tifa | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of TIFA mRNA | CTD | PMID:25975270 | Tifa | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TIFA mRNA | CTD | PMID:21215274 more ... | Tifa | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TIFA mRNA | CTD | PMID:22298810 | Tifa | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TIFA mRNA | CTD | PMID:21889950 | Tifa | Mouse | 4,4'-diaminodiphenylmethane | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of TIFA mRNA | CTD | PMID:30723492 | Tifa | Mouse | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of TIFA mRNA | CTD | PMID:28973697 | Tifa | Mouse | arsane | affects methylation | ISO | TIFA (Homo sapiens) | 6480464 | Arsenic affects the methylation of TIFA gene | CTD | PMID:25304211 | Tifa | Mouse | arsenic atom | affects methylation | ISO | TIFA (Homo sapiens) | 6480464 | Arsenic affects the methylation of TIFA gene | CTD | PMID:25304211 | Tifa | Mouse | Benoxacor | decreases expression | EXP | | 6480464 | benoxacor results in decreased expression of TIFA mRNA | CTD | PMID:34850242 | Tifa | Mouse | benzo[a]pyrene diol epoxide I | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | Tifa | Mouse | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzo(b)fluoranthene results in increased expression of TIFA mRNA | CTD | PMID:26377693 | Tifa | Mouse | bis(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in increased expression of TIFA mRNA | CTD | PMID:33754040 | Tifa | Mouse | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TIFA mRNA | CTD | PMID:26063408 | Tifa | Mouse | bisphenol A | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of TIFA mRNA | CTD | PMID:25181051 | Tifa | Mouse | cadmium dichloride | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased expression of TIFA mRNA | CTD | PMID:25993096 | Tifa | Mouse | cadmium dichloride | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of TIFA mRNA | CTD | PMID:38568856 | Tifa | Mouse | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | Tifa | Mouse | CGP 52608 | multiple interactions | ISO | TIFA (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TIFA gene] | CTD | PMID:28238834 | Tifa | Mouse | cisplatin | increases expression | ISO | TIFA (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TIFA mRNA | CTD | PMID:27594783 | Tifa | Mouse | clothianidin | increases expression | ISO | TIFA (Homo sapiens) | 6480464 | clothianidin results in increased expression of TIFA mRNA | CTD | PMID:31626844 | Tifa | Mouse | cobalt dichloride | decreases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | cobaltous chloride results in decreased expression of TIFA mRNA | CTD | PMID:24386269 | Tifa | Mouse | Cuprizon | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of TIFA mRNA | CTD | PMID:27523638 | Tifa | Mouse | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of TIFA mRNA | CTD | PMID:19770486 | Tifa | Mouse | cyclosporin A | increases expression | ISO | TIFA (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TIFA mRNA | CTD | PMID:27989131 | Tifa | Mouse | cyclosporin A | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TIFA mRNA | CTD | PMID:25562108 | Tifa | Mouse | Dibutyl phosphate | affects expression | ISO | TIFA (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TIFA mRNA | CTD | PMID:37042841 | Tifa | Mouse | dibutyl phthalate | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in increased expression of TIFA mRNA | CTD | PMID:21266533 | Tifa | Mouse | diclofenac | increases expression | EXP | | 6480464 | Diclofenac results in increased expression of TIFA mRNA | CTD | PMID:26934552 | Tifa | Mouse | dicrotophos | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of TIFA mRNA | CTD | PMID:28302478 | Tifa | Mouse | dimethylarsinic acid | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of TIFA mRNA | CTD | PMID:34876320 | Tifa | Mouse | dorsomorphin | multiple interactions | ISO | TIFA (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Tifa | Mouse | endosulfan | decreases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of TIFA mRNA | CTD | PMID:29391264 | Tifa | Mouse | entinostat | increases expression | ISO | TIFA (Homo sapiens) | 6480464 | entinostat results in increased expression of TIFA mRNA | CTD | PMID:27188386 | Tifa | Mouse | epoxiconazole | affects expression | EXP | | 6480464 | epoxiconazole affects the expression of TIFA mRNA | CTD | PMID:35436446 | Tifa | Mouse | ethanol | affects expression | EXP | | 6480464 | Ethanol affects the expression of TIFA mRNA | CTD | PMID:30319688 | Tifa | Mouse | fipronil | decreases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | fipronil results in decreased expression of TIFA mRNA | CTD | PMID:34044035 | Tifa | Mouse | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of TIFA mRNA | CTD | PMID:25629700 | Tifa | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TIFA mRNA | CTD | PMID:22206623 | Tifa | Mouse | formaldehyde | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of TIFA mRNA | CTD | PMID:20655997 | Tifa | Mouse | FR900359 | increases phosphorylation | ISO | TIFA (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of TIFA protein | CTD | PMID:37730182 | Tifa | Mouse | furan | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | furan results in increased expression of TIFA mRNA | CTD | PMID:27387713 | Tifa | Mouse | genistein | decreases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Genistein results in decreased expression of TIFA protein | CTD | PMID:24552547 | Tifa | Mouse | gentamycin | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of TIFA mRNA | CTD | PMID:22061828 | Tifa | Mouse | hypochlorous acid | decreases expression | EXP | | 6480464 | Hypochlorous Acid results in decreased expression of TIFA mRNA | CTD | PMID:19376150 | Tifa | Mouse | ketamine | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Ketamine results in increased expression of TIFA mRNA | CTD | PMID:20080153 | Tifa | Mouse | lipopolysaccharide | increases expression | EXP | | 6480464 | Lipopolysaccharides results in increased expression of TIFA mRNA | CTD | PMID:27339419 | Tifa | Mouse | lipopolysaccharide | multiple interactions | ISO | TIFA (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | Tifa | Mouse | lipopolysaccharide | increases expression | ISO | TIFA (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of TIFA mRNA | CTD | PMID:18192897 and PMID:35811015 | Tifa | Mouse | methylarsonic acid | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of TIFA mRNA | CTD | PMID:34876320 | Tifa | Mouse | orphenadrine | affects expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Orphenadrine affects the expression of TIFA mRNA | CTD | PMID:23665939 | Tifa | Mouse | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TIFA mRNA | CTD | PMID:36331819 | Tifa | Mouse | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of TIFA mRNA | CTD | PMID:19270015 | Tifa | Mouse | phenylmercury acetate | increases expression | ISO | TIFA (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of TIFA mRNA | CTD | PMID:26272509 | Tifa | Mouse | phenylmercury acetate | multiple interactions | ISO | TIFA (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TIFA mRNA | CTD | PMID:27188386 | Tifa | Mouse | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of TIFA mRNA | CTD | PMID:17426115 more ... | Tifa | Mouse | potassium chromate | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of TIFA mRNA | CTD | PMID:22714537 | Tifa | Mouse | protein kinase inhibitor | multiple interactions | ISO | TIFA (Homo sapiens) | 6480464 | Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of TIFA mRNA] | CTD | PMID:28003376 | Tifa | Mouse | quercetin | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | Quercetin results in decreased expression of TIFA mRNA | CTD | PMID:21632981 | Tifa | Mouse | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | TIFA (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | Tifa | Mouse | SB 431542 | multiple interactions | ISO | TIFA (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Tifa | Mouse | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide results in decreased expression of TIFA mRNA | CTD | PMID:19073995 and PMID:33720480 | Tifa | Mouse | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of TIFA mRNA | CTD | PMID:23221170 | Tifa | Mouse | silver atom | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | Silver results in decreased expression of TIFA mRNA | CTD | PMID:26014281 | Tifa | Mouse | silver(0) | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | Silver results in decreased expression of TIFA mRNA | CTD | PMID:26014281 | Tifa | Mouse | sodium arsenate | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of TIFA mRNA | CTD | PMID:34876320 | Tifa | Mouse | sodium arsenite | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of TIFA mRNA | CTD | PMID:38568856 | Tifa | Mouse | sodium arsenite | multiple interactions | EXP | | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of TIFA mRNA | CTD | PMID:34876320 | Tifa | Mouse | sodium dichromate | affects expression | ISO | Tifa (Rattus norvegicus) | 6480464 | sodium bichromate affects the expression of TIFA mRNA | CTD | PMID:22110744 | Tifa | Mouse | Soman | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Soman results in increased expression of TIFA mRNA | CTD | PMID:19281266 | Tifa | Mouse | succimer | multiple interactions | EXP | | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TIFA mRNA | CTD | PMID:21641980 | Tifa | Mouse | sunitinib | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of TIFA mRNA | CTD | PMID:31533062 | Tifa | Mouse | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of TIFA mRNA | CTD | PMID:20937368 | Tifa | Mouse | tetraphene | increases expression | EXP | | 6480464 | benz(a)anthracene results in increased expression of TIFA mRNA | CTD | PMID:26377693 | Tifa | Mouse | thioacetamide | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of TIFA mRNA | CTD | PMID:34492290 | Tifa | Mouse | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of TIFA mRNA | CTD | PMID:29264374 | Tifa | Mouse | trichloroethene | increases expression | ISO | Tifa (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of TIFA mRNA | CTD | PMID:33387578 | Tifa | Mouse | trichostatin A | increases expression | ISO | TIFA (Homo sapiens) | 6480464 | trichostatin A results in increased expression of TIFA mRNA | CTD | PMID:24935251 more ... | Tifa | Mouse | trichostatin A | multiple interactions | ISO | TIFA (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TIFA mRNA | CTD | PMID:27188386 | Tifa | Mouse | urethane | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | Urethane results in decreased expression of TIFA mRNA | CTD | PMID:28818685 | Tifa | Mouse | valproic acid | affects expression | ISO | TIFA (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TIFA mRNA | CTD | PMID:25979313 | Tifa | Mouse | valproic acid | multiple interactions | ISO | TIFA (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TIFA mRNA | CTD | PMID:27188386 | Tifa | Mouse | valproic acid | increases expression | ISO | TIFA (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TIFA mRNA | CTD | PMID:23179753 more ... | Tifa | Mouse | vanadyl sulfate | decreases expression | ISO | TIFA (Homo sapiens) | 6480464 | vanadyl sulfate results in decreased expression of TIFA mRNA | CTD | PMID:16330358 | Tifa | Mouse | vinclozolin | increases methylation | ISO | Tifa (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of TIFA gene | CTD | PMID:31682807 | Tifa | Mouse | vorinostat | increases expression | ISO | TIFA (Homo sapiens) | 6480464 | vorinostat results in increased expression of TIFA mRNA | CTD | PMID:27188386 | Tifa | Mouse | zoledronic acid | increases expression | ISO | TIFA (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of TIFA mRNA | CTD | PMID:24714768 | |