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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:procyclidine
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Accession:CHEBI:8448 term browser browse the term
Definition:A tertiary alcohol that consists of propan-1-ol substituted by a cyclohexyl and a phenyl group at position 1 and a pyrrolidin-1-yl group at position 3.
Synonyms:related_synonym: 1-Cyclohexyl-1-phenyl-3-pyrrolidino-1-propanol;   1-cyclohexyl-1-phenyl-3-pyrrolidin-1-yl-propan-1-ol;   Formula=C19H29NO;   InChI=1S/C19H29NO/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20/h1,3-4,9-10,18,21H,2,5-8,11-16H2;   InChIKey=WYDUSKDSKCASEF-UHFFFAOYSA-N;   SMILES=OC(CCN1CCCC1)(C1CCCCC1)c1ccccc1;   Tricyclamol;   prociclidina;   procyclidinum
 xref: Beilstein:88563;   CAS:77-37-2;   DrugBank:DB00387;   Drug_Central:2276;   HMDB:HMDB0014531;   KEGG:C07378;   KEGG:D08425;   LINCS:LSM-4396
 xref_mesh: MESH:D011352
 xref: PMID:2878700;   Patent:US2826590;   Patent:US2891890;   Reaxys:88563


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procyclidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Procyclidine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
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G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Procyclidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        pharmaceutical 19275
          drug 19275
            antidyskinesia agent 1131
              procyclidine 2
                procyclidine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      p-block molecular entity 19672
                        carbon group molecular entity 19574
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                organic heterocyclic compound 18410
                                  organic heteromonocyclic compound 16445
                                    pyrrolidines 2223
                                      procyclidine 2
                                        procyclidine hydrochloride 0
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