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Gene: Dars2 (aspartyl-tRNA synthetase 2 (mitochondrial)) Mus musculus
Symbol: Dars2
Name: aspartyl-tRNA synthetase 2 (mitochondrial)
Description: Predicted to have aspartate-tRNA ligase activity; aspartate-tRNA(Asn) ligase activity; and protein homodimerization activity. Predicted to be involved in mitochondrial asparaginyl-tRNA aminoacylation. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; midbrain; and telencephalon. Orthologous to human DARS2 (aspartyl-tRNA synthetase 2, mitochondrial); INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; dibutyl phthalate; (+)-schisandrin B (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5830468K18Rik; aspartate--tRNA ligase; aspartate--tRNA ligase, mitochondrial; aspartyl-tRNA synthetase, mitochondrial; aspRS; MGC99963
Homo sapiens (human) : DARS2 (aspartyl-tRNA synthetase 2, mitochondrial)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dars2 (aspartyl-tRNA synthetase 2 (mitochondrial))  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dars2 (aspartyl-tRNA synthetase 2, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : DARS2 (aspartyl-tRNA synthetase 2, mitochondrial)
Canis lupus familiaris (dog) : DARS2 (aspartyl-tRNA synthetase 2, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dars2 (aspartyl-tRNA synthetase 2, mitochondrial)
Sus scrofa (pig) : DARS2 (aspartyl-tRNA synthetase 2, mitochondrial)
Chlorocebus sabaeus (African green monkey) : DARS2 (aspartyl-tRNA synthetase 2, mitochondrial)
Heterocephalus glaber (naked mole-rat) : Dars2 (aspartyl-tRNA synthetase 2, mitochondrial)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1161,040,601 - 161,070,658 (-)EnsemblGRCm38mm10GRCm38
GRCm381161,037,580 - 161,070,668 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371162,970,744 - 163,000,763 (-)NCBIGRCm37mm9NCBIm37
MGSCv361162,878,252 - 162,907,326 (-)NCBImm8
Celera1163,482,244 - 163,511,984 (-)NCBICelera
Cytogenetic Map1H2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dars2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550719
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.