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Gene: Mfge8 (milk fat globule-EGF factor 8 protein) Mus musculus
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Symbol: Mfge8
Name: milk fat globule-EGF factor 8 protein
Description: Exhibits integrin binding activity; phosphatidylethanolamine binding activity; and phosphatidylserine binding activity. Involved in phagocytosis and positive regulation of phagocytosis. Localizes to the external side of plasma membrane; extracellular space; and extrinsic component of plasma membrane. Human ortholog(s) of this gene implicated in temporal arteritis. Is expressed in several structures, including alimentary system; cap mesenchyme; central nervous system; reproductive system; and sensory organ. Orthologous to human MFGE8 (milk fat globule-EGF factor 8 protein); INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408458; AI325141; EGF/factor VIII; lactadherin; MFG-E8; Mfgm; milk fat globule glycoprotein; MP47; P47; SED1; sperm surface protein SP47
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl779,133,768 - 79,149,060 (-)Ensembl
GRCm38779,133,768 - 79,149,060 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37786,278,654 - 86,293,946 (-)NCBIGRCm37mm9NCBIm37
MGSCv36779,007,282 - 79,022,526 (-)NCBImm8
Celera776,533,114 - 76,548,369 (-)NCBICelera
Cytogenetic Map7 D2NCBI
cM Map744.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mfge8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10895
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.