Prkcg (protein kinase C, gamma) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Prkcg (protein kinase C, gamma) Mus musculus
Analyze
Symbol: Prkcg
Name: protein kinase C, gamma
RGD ID: 11147
MGI Page MGI
Description: Predicted to enable calcium,diacylglycerol-dependent serine/threonine kinase activity and protein serine/threonine/tyrosine kinase activity. Involved in several processes, including modulation of chemical synaptic transmission; negative regulation of protein metabolic process; and response to morphine. Acts upstream of or within chemosensory behavior and regulation of phagocytosis. Located in several cellular components, including dendrite; postsynaptic density; and synaptic membrane. Is active in calyx of Held and presynaptic cytosol. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and hemolymphoid system gland. Used to study spinocerebellar ataxia type 14. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 14. Orthologous to human PRKCG (protein kinase C gamma).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC130440; Pkc; PKC-gamma; Pkcc; PKCga; PKCgamma; Prk; Prkcc; protein kinase C gamma type
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3973,352,038 - 3,379,615 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl73,337,704 - 3,379,615 (+)EnsemblGRCm39 Ensembl
GRCm3873,303,532 - 3,331,099 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl73,289,179 - 3,331,099 (+)EnsemblGRCm38mm10GRCm38
MGSCv3773,303,658 - 3,331,005 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3673,303,658 - 3,331,005 (+)NCBIMGSCv36mm8
Celera73,254,377 - 3,281,532 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map71.93NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP,ISO)
(S)-alpha-methyl-4-carboxyphenylglycine  (ISO)
(S)-naringenin  (ISO)
1,2-dimethylhydrazine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-amino-5-phosphonopentanoic acid  (ISO)
2-methoxyethanol  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bryostatin 1  (ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
Calphostin C  (EXP)
celecoxib  (EXP)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (ISO)
cyclophosphamide  (ISO)
daidzein  (ISO)
deoxynivalenol  (EXP)
dimethylarsinic acid  (ISO)
dizocilpine maleate  (EXP,ISO)
endosulfan  (ISO)
ethanol  (EXP,ISO)
ethylparaben  (ISO)
fenamidone  (EXP)
fluoxetine  (ISO)
FR900359  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (EXP)
ketamine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lidocaine  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
memantine  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methoxyacetic acid  (ISO)
Mezerein  (ISO)
morphine  (EXP,ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N-methyl-D-aspartic acid  (EXP)
ozone  (ISO)
paraquat  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phencyclidine  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
pioglitazone  (ISO)
quercetin  (EXP)
Rebamipide  (ISO)
remifentanil  (ISO)
resveratrol  (ISO)
Ro 31-8220  (EXP)
S-nitroso-N-acetyl-D-penicillamine  (EXP)
sirolimus  (ISO)
sodium arsenite  (ISO)
thiram  (ISO)
triclosan  (ISO)
trimethylarsine oxide  (ISO)
triptonide  (EXP)
trovafloxacin  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Segregation of a PRKCG mutation in two RP11 families. Al-Maghtheh M, etal., Am J Hum Genet 1998 May;62(5):1248-52.
2. Transient translocation of protein kinase Cgamma in hippocampal long-term potentiation depends on activation of metabotropic glutamate receptors. Angenstein F, etal., Neuroscience. 1999;93(4):1289-95. doi: 10.1016/s0306-4522(99)00315-2.
3. Missense mutations in the regulatory domain of PKC gamma: a new mechanism for dominant nonepisodic cerebellar ataxia. Chen DH, etal., Am J Hum Genet 2003 Apr;72(4):839-49. Epub 2003 Mar 17.
4. Protein kinase C-gamma and calcium/calmodulin-dependent protein kinase II-alpha are persistently translocated to cell membranes of the rat brain during and after middle cerebral artery occlusion. Matsumoto S, etal., J Cereb Blood Flow Metab 2004 Jan;24(1):54-61.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Protein kinase C: poised to signal. Newton AC Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E395-402. Epub 2009 Nov 24.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. D-2-amino-5-phosphonopentanoic acid inhibits intrathecal pertussis toxin-induced thermal hyperalgesia and protein kinase Cgamma up-regulation. Wen ZH, etal., Brain Res. 2003 Feb 14;963(1-2):1-7. doi: 10.1016/s0006-8993(02)03751-4.
15. Regulation of insulin receptor function. Youngren JF Cell Mol Life Sci. 2007 Apr;64(7-8):873-91.
Additional References at PubMed
PMID:1460423   PMID:1628813   PMID:1638085   PMID:1923524   PMID:1970795   PMID:1981054   PMID:2307474   PMID:2471069   PMID:2590242   PMID:2842249   PMID:7513693   PMID:7606770  
PMID:7628620   PMID:7670497   PMID:7731960   PMID:7760054   PMID:7985811   PMID:8069308   PMID:8269509   PMID:8269510   PMID:8288260   PMID:8428669   PMID:8548808   PMID:8548809  
PMID:8663257   PMID:8666393   PMID:8812459   PMID:8812484   PMID:8825654   PMID:8833158   PMID:8889548   PMID:8922669   PMID:8946062   PMID:8948582   PMID:9136988   PMID:9143514  
PMID:9149948   PMID:9323205   PMID:9854032   PMID:9857183   PMID:9878254   PMID:9890937   PMID:10195808   PMID:10349636   PMID:10391924   PMID:10767319   PMID:10802123   PMID:10862698  
PMID:10879655   PMID:10882525   PMID:10891582   PMID:10979601   PMID:11003710   PMID:11042159   PMID:11076861   PMID:11170751   PMID:11217851   PMID:11246146   PMID:11278552   PMID:11438608  
PMID:11493566   PMID:11498051   PMID:11549583   PMID:11606660   PMID:11698038   PMID:11731061   PMID:11934475   PMID:12123716   PMID:12359310   PMID:12466851   PMID:12477932   PMID:12649378  
PMID:12699785   PMID:12761849   PMID:12832475   PMID:12859346   PMID:14610273   PMID:14613966   PMID:14667440   PMID:14680764   PMID:14690876   PMID:14985469   PMID:15006698   PMID:15051735  
PMID:15229137   PMID:15322115   PMID:15364414   PMID:15367584   PMID:15491280   PMID:15557194   PMID:15590069   PMID:15647493   PMID:15695617   PMID:16106361   PMID:16141072   PMID:16141073  
PMID:16183862   PMID:16271712   PMID:16446141   PMID:16516881   PMID:16537572   PMID:16602821   PMID:16767509   PMID:17050852   PMID:17114649   PMID:17145500   PMID:17199045   PMID:17522312  
PMID:17661397   PMID:17904530   PMID:18086710   PMID:18155191   PMID:18242849   PMID:18430798   PMID:18473171   PMID:18603407   PMID:18641643   PMID:18652891   PMID:18685019   PMID:18774262  
PMID:18957218   PMID:19041943   PMID:19060919   PMID:19088125   PMID:19365031   PMID:19466636   PMID:19531484   PMID:19556521   PMID:19616129   PMID:19706528   PMID:20110327   PMID:20346763  
PMID:20359526   PMID:20362561   PMID:20392936   PMID:20705605   PMID:20938103   PMID:21056652   PMID:21111029   PMID:21267068   PMID:21273552   PMID:21303853   PMID:21319224   PMID:21335048  
PMID:21536681   PMID:21685893   PMID:21710437   PMID:21873635   PMID:21976518   PMID:22171059   PMID:22284184   PMID:22305526   PMID:22678282   PMID:22794259   PMID:22797923   PMID:22819675  
PMID:23115168   PMID:23175820   PMID:23185022   PMID:23525041   PMID:23564155   PMID:23587021   PMID:23793062   PMID:23824069   PMID:23960082   PMID:24027274   PMID:24125957   PMID:24478091  
PMID:24700503   PMID:24794094   PMID:24835466   PMID:24863469   PMID:24930700   PMID:25002511   PMID:25009260   PMID:25037921   PMID:25217572   PMID:25592416   PMID:25834049   PMID:26025364  
PMID:26399641   PMID:26514267   PMID:26830346   PMID:26848828   PMID:26858447   PMID:26965927   PMID:27063791   PMID:27160897   PMID:27307229   PMID:27507650   PMID:27510769   PMID:27531930  
PMID:27889896   PMID:28041852   PMID:28228266   PMID:28671696   PMID:28706196   PMID:28726275   PMID:28760865   PMID:29049849   PMID:29167402   PMID:29213092   PMID:29432535   PMID:29550816  
PMID:29734780   PMID:29744369   PMID:29874580   PMID:30013171   PMID:30016727   PMID:30068389   PMID:30485813   PMID:30562941   PMID:30734936   PMID:31003036   PMID:31152445   PMID:31242289  
PMID:32051001   PMID:32325033   PMID:32343785   PMID:32707082   PMID:32860158   PMID:32996086   PMID:33100228   PMID:33114041   PMID:33181066   PMID:33472083   PMID:33478986   PMID:33553137  
PMID:34290081   PMID:34321999   PMID:34815492   PMID:35145028   PMID:36152136   PMID:36334588   PMID:36417873   PMID:37108107  


Genomics

Comparative Map Data
Prkcg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3973,352,038 - 3,379,615 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl73,337,704 - 3,379,615 (+)EnsemblGRCm39 Ensembl
GRCm3873,303,532 - 3,331,099 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl73,289,179 - 3,331,099 (+)EnsemblGRCm38mm10GRCm38
MGSCv3773,303,658 - 3,331,005 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3673,303,658 - 3,331,005 (+)NCBIMGSCv36mm8
Celera73,254,377 - 3,281,532 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map71.93NCBI
PRKCG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381953,881,094 - 53,907,652 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1953,879,190 - 53,907,652 (+)EnsemblGRCh38hg38GRCh38
GRCh371954,385,451 - 54,410,906 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361959,077,279 - 59,102,713 (+)NCBINCBI36Build 36hg18NCBI36
Build 341959,077,278 - 59,102,713NCBI
Celera1951,426,508 - 51,451,938 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1950,704,660 - 50,730,288 (+)NCBIHuRef
CHM1_11954,386,673 - 54,412,682 (+)NCBICHM1_1
T2T-CHM13v2.01956,960,799 - 56,987,358 (+)NCBIT2T-CHM13v2.0
Prkcg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8174,748,272 - 74,777,611 (-)NCBIGRCr8
mRatBN7.2165,832,851 - 65,860,676 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,832,855 - 65,859,384 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx171,281,002 - 71,307,568 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0179,703,990 - 79,730,541 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0173,037,259 - 73,063,810 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0164,407,098 - 64,433,698 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl164,407,114 - 64,433,636 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0163,399,153 - 63,425,645 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4164,145,749 - 64,172,712 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1164,223,859 - 64,250,823 (-)NCBI
Celera163,557,681 - 63,584,062 (-)NCBICelera
Cytogenetic Map1q12NCBI
Prkcg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955604262,071 - 279,259 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955604262,182 - 279,259 (-)NCBIChiLan1.0ChiLan1.0
PRKCG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22059,894,490 - 59,920,148 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11961,816,427 - 61,842,055 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01950,823,372 - 50,849,003 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11959,671,762 - 59,696,728 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1959,672,097 - 59,695,977 (+)Ensemblpanpan1.1panPan2
PRKCG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11103,295,110 - 103,312,562 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1103,361,568 - 103,378,698 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01103,950,090 - 103,967,279 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1103,950,021 - 103,967,324 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11103,582,545 - 103,599,712 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01103,344,283 - 103,361,444 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01104,063,257 - 104,080,431 (-)NCBIUU_Cfam_GSD_1.0
Prkcg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093492,832,669 - 2,850,276 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493699487,519 - 105,134 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493699487,525 - 105,125 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKCG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl656,213,480 - 56,234,210 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1656,213,479 - 56,235,683 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2652,981,725 - 53,001,720 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRKCG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1646,574,560 - 46,600,329 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl646,575,439 - 46,600,364 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607326,653,473 - 26,678,402 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prkcg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248322,547,535 - 2,566,402 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248322,548,286 - 2,566,365 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:532
Count of miRNA genes:335
Interacting mature miRNAs:361
Transcripts:ENSMUST00000100301, ENSMUST00000172109
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301177Vent3_mventricular size 3 (mouse)Not determined7120511925Mouse
10054067Sle20_msystematic lupus erythematosus susceptibility 20 (mouse)Not determined7120511925Mouse
1302188Lxw6_mlupus BXSB x NZW 6 (mouse)Not determined7121698146Mouse
12904941Edlmmq6_mextensor digitorum longus muscle mass QTL 6 (mouse)7121821047Mouse
12904948Tammq5_mtibialis anterior muscle mass QTL 5 (mouse)7121821047Mouse
12904953Gmmq5_mgastrocnemius muscle mass QTL 5 (mouse)7121821047Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1302115Abhr3_mallergen-induced bronchial hyperresponsiveness 3 (mouse)Not determined7331599616637423Mouse
1301115Lrdm1_mlymphoproliferation (Fas) renal disease modifier 1 (mouse)Not determined7335204824879418Mouse

Markers in Region
Prkcc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv3773,330,143 - 3,330,544UniSTSGRCm37
Celera73,280,669 - 3,281,070UniSTS
Cytogenetic Map7A1UniSTS
cM Map72.0UniSTS
cM Map71.93UniSTS
cM Map72.0UniSTS
Pkcc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3873,330,237 - 3,330,340UniSTSGRCm38
MGSCv3773,330,546 - 3,330,649UniSTSGRCm37
Celera73,281,072 - 3,281,175UniSTS
Cytogenetic Map7A1UniSTS
cM Map72.0UniSTS
Prkcc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3873,329,834 - 3,330,235UniSTSGRCm38
MGSCv3773,330,143 - 3,330,544UniSTSGRCm37
Celera73,280,669 - 3,281,070UniSTS
Cytogenetic Map7A1UniSTS
cM Map71.93UniSTS
cM Map72.0UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000100301   ⟹   ENSMUSP00000097874
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl73,352,038 - 3,379,615 (+)Ensembl
GRCm38.p6 Ensembl73,303,522 - 3,331,099 (+)Ensembl
RefSeq Acc Id: ENSMUST00000172109   ⟹   ENSMUSP00000131351
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl73,352,161 - 3,378,883 (+)Ensembl
GRCm38.p6 Ensembl73,303,645 - 3,330,367 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203081   ⟹   ENSMUSP00000145498
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl73,353,860 - 3,367,528 (+)Ensembl
GRCm38.p6 Ensembl73,305,344 - 3,319,012 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203454
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl73,377,354 - 3,378,536 (+)Ensembl
GRCm38.p6 Ensembl73,328,838 - 3,330,020 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203600
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl73,337,704 - 3,352,827 (+)Ensembl
GRCm38.p6 Ensembl73,289,179 - 3,304,311 (+)Ensembl
RefSeq Acc Id: NM_001291434   ⟹   NP_001278363
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3973,352,038 - 3,379,615 (+)NCBI
GRCm3873,303,532 - 3,331,099 (+)NCBI
Celera73,254,377 - 3,281,927 (+)NCBI
Sequence:
RefSeq Acc Id: NM_011102   ⟹   NP_035232
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3973,352,038 - 3,379,615 (+)NCBI
GRCm3873,303,532 - 3,331,099 (+)NCBI
MGSCv3773,303,658 - 3,331,005 (+)RGD
Celera73,254,377 - 3,281,927 (+)NCBI
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_184420
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3973,352,038 - 3,379,615 (+)NCBI
RefSeq Acc Id: NR_184421
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3973,352,038 - 3,379,615 (+)NCBI
RefSeq Acc Id: XM_036152788   ⟹   XP_036008681
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3973,361,213 - 3,379,615 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_035232   ⟸   NM_011102
- Peptide Label: isoform 1
- UniProtKB: P05697 (UniProtKB/Swiss-Prot),   P63318 (UniProtKB/Swiss-Prot),   Q3UN66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278363   ⟸   NM_001291434
- Peptide Label: isoform 2
- UniProtKB: Q2NKI4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000145498   ⟸   ENSMUST00000203081
RefSeq Acc Id: ENSMUSP00000131351   ⟸   ENSMUST00000172109
RefSeq Acc Id: ENSMUSP00000097874   ⟸   ENSMUST00000100301
RefSeq Acc Id: XP_036008681   ⟸   XM_036152788
- Peptide Label: isoform X1
Protein Domains
AGC-kinase C-terminal   C2   Phorbol-ester/DAG-type   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63318-F1-model_v2 AlphaFold P63318 1-697 view protein structure

Promoters
RGD ID:6841843
Promoter ID:MM_KWN:48370
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000100301,   NM_011102,   UC009EUT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3673,302,821 - 3,304,082 (+)MPROMDB
RGD ID:6891602
Promoter ID:EPDNEW_M9252
Type:initiation region
Name:Prkcg_1
Description:Mus musculus protein kinase C, gamma , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3873,303,522 - 3,303,582EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97597 AgrOrtholog
Ensembl Genes ENSMUSG00000078816 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000100301 ENTREZGENE
  ENSMUST00000100301.11 UniProtKB/Swiss-Prot
  ENSMUST00000172109 ENTREZGENE
  ENSMUST00000172109.4 UniProtKB/TrEMBL
  ENSMUST00000203081.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C1-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAG/PE-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_C_a/b/g UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18752 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97597 ENTREZGENE
NCBI Gene 18752 ENTREZGENE
PANTHER PROTEIN KINASE C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN KINASE C, MU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prkcg PhenoGen
PIRSF PKC_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAGPEDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TK_X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57889 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SWF4_MOUSE UniProtKB/TrEMBL
  KPCG_MOUSE UniProtKB/Swiss-Prot
  P05697 ENTREZGENE
  P63318 ENTREZGENE
  Q2NKI4 ENTREZGENE, UniProtKB/TrEMBL
  Q3UN66 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary P05697 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-06-12 Prkcg  protein kinase C, gamma  Prkcc  protein kinase C, gamma  Symbol and/or name change 5135510 APPROVED