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Gene: Rtn4 (reticulon 4) Mus musculus
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Symbol: Rtn4
Name: reticulon 4
Description: Predicted to have cadherin binding activity; protein homodimerization activity; and ubiquitin protein ligase binding activity. Involved in several processes, including blood vessel morphogenesis; neurogenesis; and regulation of vasculature development. Localizes to several cellular components, including dendritic growth cone; neuronal cell body; and postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; limb mesenchyme; peripheral nervous system ganglion; and sensory organ. Orthologous to human RTN4 (reticulon 4); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110020G17Rik; AA407876; AA409940; AA960376; ASY; C130026I10Rik; KIAA4153; mKIAA0886; mKIAA4153; neurite outgrowth inhibitor; NgA; NOGO; Nogo-A; Nogo-B; Nogo-C; NSP-CL; reticulon-4
Orthologs:
Homo sapiens (human) : RTN4 (reticulon 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rtn4 (reticulon 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rtn4 (reticulon 4)
Pan paniscus (bonobo/pygmy chimpanzee) : RTN4 (reticulon 4)
Canis lupus familiaris (dog) : RTN4 (reticulon 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rtn4 (reticulon 4)
Sus scrofa (pig) : RTN4 (reticulon 4)
Chlorocebus sabaeus (African green monkey) : RTN4 (reticulon 4)
Heterocephalus glaber (naked mole-rat) : Rtn4 (reticulon 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1129,692,947 - 29,744,331 (+)EnsemblGRCm38mm10GRCm38
GRCm381129,692,898 - 29,744,414 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371129,592,898 - 29,644,414 (+)NCBIGRCm37mm9NCBIm37
MGSCv361129,592,947 - 29,642,916 (+)NCBImm8
Celera1132,055,366 - 32,110,540 (+)NCBICelera
Cytogenetic Map11A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rtn4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730920
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.