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Gene: Rtn4 (reticulon 4) Mus musculus
Symbol: Rtn4
Name: reticulon 4
Description: Predicted to have cadherin binding activity; protein homodimerization activity; and ubiquitin protein ligase binding activity. Involved in several processes, including blood vessel morphogenesis; neurogenesis; and regulation of vasculature development. Localizes to several cellular components, including dendritic growth cone; neuronal cell body; and postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; limb mesenchyme; peripheral nervous system ganglion; and sensory organ. Orthologous to human RTN4 (reticulon 4); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110020G17Rik; AA407876; AA409940; AA960376; ASY; C130026I10Rik; KIAA4153; mKIAA0886; mKIAA4153; neurite outgrowth inhibitor; NgA; NOGO; Nogo-A; Nogo-B; Nogo-C; NSP-CL; reticulon-4
Homo sapiens (human) : RTN4 (reticulon 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rtn4 (reticulon 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rtn4 (reticulon 4)
Pan paniscus (bonobo/pygmy chimpanzee) : RTN4 (reticulon 4)
Canis lupus familiaris (dog) : RTN4 (reticulon 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rtn4 (reticulon 4)
Sus scrofa (pig) : RTN4 (reticulon 4)
Chlorocebus sabaeus (African green monkey) : RTN4 (reticulon 4)
Heterocephalus glaber (naked mole-rat) : Rtn4 (reticulon 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1129,692,947 - 29,744,331 (+)EnsemblGRCm38mm10GRCm38
GRCm381129,692,898 - 29,744,414 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371129,592,898 - 29,644,414 (+)NCBIGRCm37mm9NCBIm37
MGSCv361129,592,947 - 29,642,916 (+)NCBImm8
Celera1132,055,366 - 32,110,540 (+)NCBICelera
Cytogenetic Map11A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rtn4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730920
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.