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Gene: Gabrb3 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 3) Mus musculus
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Symbol: Gabrb3
Name: gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
RGD ID: 10614
Description: Exhibits GABA-A receptor activity and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Contributes to GABA-gated chloride ion channel activity. Involved in several processes, including inhibitory postsynaptic potential; inner ear development; and nervous system development. Localizes to GABA-A receptor complex; GABA-ergic synapse; and plasma membrane. Is expressed in several structures, including central nervous system; eye; jaw; and olfactory epithelium. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in childhood absence epilepsy and early infantile epileptic encephalopathy 43. Orthologous to human GABRB3 (gamma-aminobutyric acid type A receptor subunit beta3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-fluorouracil; acetic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A230092K12Rik; AW049585; beta3; cleft palate 1; Cp1; GABA(A) receptor subunit beta-3; Gabrb; Gabrb-3; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 3; gamma-aminobutyric acid receptor subunit beta-3
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl757,419,692 - 57,828,802 (+)EnsemblGRCm38mm10GRCm38
GRCm38757,590,518 - 57,828,802 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37764,845,904 - 65,084,172 (+)NCBIGRCm37mm9NCBIm37
MGSCv36757,458,398 - 57,696,666 (+)NCBImm8
Celera754,911,328 - 55,150,383 (+)NCBICelera
Cytogenetic Map7B5NCBI
cM Map733.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Gabrb3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10614
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.