Per2 (period circadian clock 2) - Rat Genome Database

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Gene: Per2 (period circadian clock 2) Mus musculus
Analyze
Symbol: Per2
Name: period circadian clock 2
RGD ID: 62238
MGI Page MGI
Description: Enables several functions, including enzyme binding activity; nucleic acid binding activity; and transcription corepressor binding activity. Involved in several processes, including gluconeogenesis; monocarboxylic acid metabolic process; and regulation of gene expression. Acts upstream of or within circadian rhythm and negative regulation of transcription by RNA polymerase II. Located in nucleus and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study advanced sleep phase syndrome 1. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome and advanced sleep phase syndrome 1. Orthologous to human PER2 (period circadian regulator 2).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: circadian clock protein PERIOD 2; mKIAA0347; mPe; mPer2; period 2; period circadian protein homolog 2; period homolog 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39191,343,699 - 91,387,072 (-)NCBIGRCm39mm39
GRCm39 Ensembl191,343,704 - 91,387,046 (-)Ensembl
GRCm38191,415,977 - 91,459,351 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl191,415,982 - 91,459,324 (-)EnsemblGRCm38mm10GRCm38
MGSCv37193,312,559 - 93,355,905 (-)NCBIGRCm37mm9NCBIm37
MGSCv36193,246,388 - 93,289,702 (-)NCBImm8
Celera194,353,350 - 94,396,834 (-)NCBICelera
Cytogenetic Map1DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-epicatechin-3-O-gallate  (ISO)
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(R)-noradrenaline  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
acamprosate  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
amphetamine  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (ISO)
butanal  (ISO)
C60 fullerene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP)
CGS-21680  (ISO)
chloroprene  (EXP,ISO)
choline  (EXP)
chrysene  (EXP)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cyanocob(III)alamin  (EXP)
cyclosporin A  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethyl maleate  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
Erionite  (EXP)
ethanol  (EXP,ISO)
ferric oxide  (EXP)
flavonoids  (ISO)
fluoranthene  (EXP)
fluoxetine  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
furan  (ISO)
gallic acid  (ISO)
gallocatechin  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gentamycin  (ISO)
glycine betaine  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
L-methionine  (EXP)
leflunomide  (ISO)
linsidomine  (EXP)
manganese(II) chloride  (ISO)
melatonin  (ISO)
menadione  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (ISO)
methotrexate  (EXP,ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
milrinone  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
morphine  (EXP,ISO)
N-nitrosodiethylamine  (ISO)
orphenadrine  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
phenol  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
plumbagin  (EXP)
potassium chromate  (ISO)
potassium dichromate  (EXP)
prednisolone  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (EXP,ISO)
propanal  (ISO)
quercetin  (ISO)
raloxifene  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
sevoflurane  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium dodecyl sulfate  (ISO)
Soman  (ISO)
styrene  (EXP)
sulforaphane  (EXP)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
tetraphene  (EXP)
thapsigargin  (ISO)
titanium dioxide  (EXP,ISO)
torcetrapib  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vorinostat  (EXP,ISO)
zalcitabine  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IDA)
cytosol  (ISO,TAS)
nucleoplasm  (ISO,TAS)
nucleus  (IBA,IDA,IPI,ISO)
perinuclear region of cytoplasm  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal basal metabolism  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal body weight  (IAGP)
abnormal bone marrow cell morphology/development  (IAGP)
abnormal bone mineralization  (IEA)
abnormal brain wave pattern  (IAGP)
abnormal circadian behavior  (IEA)
abnormal circadian behavior period  (IAGP)
abnormal circadian sleep/wake cycle  (IAGP)
abnormal circadian temperature homeostasis  (IAGP)
abnormal coat/hair pigmentation  (IEA)
abnormal eye physiology  (IAGP)
abnormal fibroblast physiology  (IAGP)
abnormal food intake  (IAGP)
abnormal food preference  (IAGP)
abnormal hematopoietic stem cell physiology  (IAGP)
abnormal hypothalamus physiology  (IAGP)
abnormal liver physiology  (IAGP)
abnormal locomotor circadian rhythm  (IAGP)
abnormal male preputial gland morphology  (IAGP)
abnormal maternal behavior  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal pregnancy  (IAGP)
abnormal retina morphology  (IAGP)
abnormal retinal vasculature morphology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal sleep pattern  (IAGP)
abnormal urine catecholamine level  (IAGP)
absent estrous cycle  (IAGP)
arrhythmic circadian behavior persistence  (IAGP)
decreased bone ossification  (IAGP)
decreased cellular sensitivity to gamma-irradiation  (IAGP)
decreased hematopoietic stem cell proliferation  (IAGP)
decreased litter size  (IAGP)
decreased osteoblast cell number  (IAGP)
delayed circadian behavior phase  (IEA)
early reproductive senescence  (IAGP)
enhanced behavioral response to cocaine  (IAGP)
enhanced conditioned place preference behavior  (IAGP)
impaired wound healing  (IAGP)
improved glucose tolerance  (IAGP)
increased body weight  (IAGP)
increased bone mass  (IAGP)
increased bone ossification  (IAGP)
increased bone volume  (IAGP)
increased circulating alkaline phosphatase level  (IEA)
increased circulating leptin level  (IAGP)
increased hematopoietic stem cell number  (IAGP)
increased incidence of tumors by ionizing radiation induction  (IAGP)
increased lymphoma incidence  (IAGP)
increased mortality induced by gamma-irradiation  (IAGP)
increased osteoblast cell number  (IAGP)
increased osteoblast proliferation  (IAGP)
increased salivary gland tumor incidence  (IAGP)
no abnormal phenotype detected  (IAGP)
premature death  (IAGP)
prolonged circadian behavior period  (IAGP)
prolonged estrous cycle  (IAGP)
pup cannibalization  (IAGP)
reduced female fertility  (IAGP)
salivary gland epithelial hyperplasia  (IAGP)
shortened circadian behavior period  (IAGP)
References

Additional References at PubMed
PMID:9427249   PMID:9428527   PMID:9582067   PMID:9619629   PMID:9856465   PMID:9856466   PMID:9920673   PMID:9988221   PMID:9989497   PMID:10077321   PMID:10208599   PMID:10349636  
PMID:10408444   PMID:10428031   PMID:10487202   PMID:10508692   PMID:10617474   PMID:10807566   PMID:10837028   PMID:10848614   PMID:10891604   PMID:10899319   PMID:11042159   PMID:11042357  
PMID:11076861   PMID:11207804   PMID:11217851   PMID:11389837   PMID:11395012   PMID:11591712   PMID:11865049   PMID:11889036   PMID:11959112   PMID:12024206   PMID:12032351   PMID:12054191  
PMID:12084940   PMID:12150932   PMID:12372028   PMID:12372299   PMID:12374857   PMID:12381662   PMID:12383239   PMID:12466851   PMID:12477932   PMID:12531511   PMID:12622829   PMID:12693553  
PMID:12693867   PMID:12738229   PMID:12775559   PMID:12824769   PMID:12843397   PMID:12897057   PMID:12916720   PMID:14522008   PMID:14645221   PMID:14657179   PMID:14681479   PMID:14701732  
PMID:14963227   PMID:15009158   PMID:15031135   PMID:15269772   PMID:15369776   PMID:15608650   PMID:15618518   PMID:15620658   PMID:15689618   PMID:15699353   PMID:15713645   PMID:15741322  
PMID:15767683   PMID:15800623   PMID:15817328   PMID:15860628   PMID:15959842   PMID:15985538   PMID:16097765   PMID:16141072   PMID:16141073   PMID:16143109   PMID:16280364   PMID:16421573  
PMID:16474407   PMID:16478995   PMID:16595674   PMID:16602821   PMID:16717091   PMID:16777965   PMID:16813562   PMID:16827798   PMID:16845385   PMID:16861663   PMID:16890544   PMID:16978068  
PMID:17055980   PMID:17138670   PMID:17182630   PMID:17202855   PMID:17218255   PMID:17274955   PMID:17298173   PMID:17310242   PMID:17368741   PMID:17404161   PMID:17417633   PMID:17462724  
PMID:17463252   PMID:17482552   PMID:17525164   PMID:17637349   PMID:17715397   PMID:17901046   PMID:17945005   PMID:17986006   PMID:17996461   PMID:18057941   PMID:18256599   PMID:18258755  
PMID:18287559   PMID:18346860   PMID:18367514   PMID:18419744   PMID:18430226   PMID:18439826   PMID:18446212   PMID:18448638   PMID:18479150   PMID:18487196   PMID:18616823   PMID:18651214  
PMID:18662546   PMID:18728223   PMID:18768762   PMID:18779586   PMID:18782782   PMID:18786554   PMID:18945877   PMID:18959477   PMID:18981300   PMID:18999929   PMID:19010825   PMID:19010962  
PMID:19020302   PMID:19032592   PMID:19037239   PMID:19038280   PMID:19056852   PMID:19078963   PMID:19106159   PMID:19168071   PMID:19179447   PMID:19204282   PMID:19217292   PMID:19222558  
PMID:19299560   PMID:19327139   PMID:19402751   PMID:19414365   PMID:19414593   PMID:19477955   PMID:19523042   PMID:19587447   PMID:19605937   PMID:19698763   PMID:19718444   PMID:19738906  
PMID:19740747   PMID:19741146   PMID:19786732   PMID:19805059   PMID:19805326   PMID:19829696   PMID:19840112   PMID:19917250   PMID:19926610   PMID:19926612   PMID:19926812   PMID:19948962  
PMID:20030538   PMID:20043880   PMID:20053965   PMID:20059953   PMID:20061537   PMID:20072700   PMID:20075296   PMID:20159955   PMID:20180860   PMID:20211142   PMID:20236181   PMID:20300063  
PMID:20352049   PMID:20370466   PMID:20404168   PMID:20421981   PMID:20434889   PMID:20450826   PMID:20539819   PMID:20543573   PMID:20560710   PMID:20562852   PMID:20634945   PMID:20668203  
PMID:20696890   PMID:20826680   PMID:20829506   PMID:20832105   PMID:20840750   PMID:20887817   PMID:20932939   PMID:20944004   PMID:20947768   PMID:20967239   PMID:21035761   PMID:21113167  
PMID:21151601   PMID:21156215   PMID:21179498   PMID:21186050   PMID:21267068   PMID:21285316   PMID:21324900   PMID:21366728   PMID:21382453   PMID:21392557   PMID:21458659   PMID:21488990  
PMID:21549097   PMID:21559484   PMID:21613214   PMID:21624349   PMID:21628550   PMID:21655193   PMID:21680841   PMID:21703244   PMID:21768648   PMID:21773940   PMID:21793695   PMID:21818120  
PMID:21873635   PMID:21901130   PMID:21915348   PMID:21929298   PMID:21969583   PMID:22039518   PMID:22043319   PMID:22069332   PMID:22080784   PMID:22140039   PMID:22154820   PMID:22158133  
PMID:22159024   PMID:22170608   PMID:22184247   PMID:22208286   PMID:22210883   PMID:22236088   PMID:22238756   PMID:22261359   PMID:22274616   PMID:22331899   PMID:22341446   PMID:22342842  
PMID:22362755   PMID:22405069   PMID:22460952   PMID:22504074   PMID:22504483   PMID:22558277   PMID:22723262   PMID:22734566   PMID:22764243   PMID:22767893   PMID:22823489   PMID:22833565  
PMID:22891330   PMID:22905719   PMID:22934083   PMID:22936566   PMID:22966205   PMID:22988135   PMID:22988430   PMID:23024437   PMID:23039899   PMID:23079727   PMID:23110090   PMID:23193187  
PMID:23213472   PMID:23223373   PMID:23267082   PMID:23273571   PMID:23285241   PMID:23333842   PMID:23351077   PMID:23372705   PMID:23418588   PMID:23434278   PMID:23434933   PMID:23439698  
PMID:23450268   PMID:23452855   PMID:23452856   PMID:23503662   PMID:23505514   PMID:23516567   PMID:23555304   PMID:23580255   PMID:23608482   PMID:23616524   PMID:23690597   PMID:23690615  
PMID:23735497   PMID:23736292   PMID:23771689   PMID:23785138   PMID:23869717   PMID:23951220   PMID:23977055   PMID:24049733   PMID:24049741   PMID:24051492   PMID:24062487   PMID:24091726  
PMID:24094851   PMID:24099911   PMID:24167276   PMID:24268780   PMID:24336415   PMID:24374345   PMID:24385426   PMID:24413057   PMID:24477539   PMID:24498074   PMID:24498336   PMID:24506873  
PMID:24527953   PMID:24582500   PMID:24583017   PMID:24603368   PMID:24621388   PMID:24656826   PMID:24682205   PMID:24736997   PMID:24737000   PMID:24760863   PMID:24767996   PMID:24770415  
PMID:24797626   PMID:24829500   PMID:24842115   PMID:24843129   PMID:24845399   PMID:24855952   PMID:24897937   PMID:24933288   PMID:24952961   PMID:24997189   PMID:25063847   PMID:25127877  
PMID:25145629   PMID:25190567   PMID:25217379   PMID:25228643   PMID:25268972   PMID:25288642   PMID:25417104   PMID:25431853   PMID:25485682   PMID:25514904   PMID:25525750   PMID:25573753  
PMID:25581923   PMID:25660546   PMID:25689298   PMID:25741729   PMID:25741730   PMID:25756610   PMID:25779967   PMID:25821984   PMID:25846207   PMID:25888034   PMID:25993523   PMID:26026603  
PMID:26073568   PMID:26161796   PMID:26166747   PMID:26188089   PMID:26207312   PMID:26232227   PMID:26323038   PMID:26332085   PMID:26392540   PMID:26431025   PMID:26456331   PMID:26456390  
PMID:26464996   PMID:26489367   PMID:26542580   PMID:26542738   PMID:26580614   PMID:26588574   PMID:26617050   PMID:26652002   PMID:26657859   PMID:26776516   PMID:26781276   PMID:26838474  
PMID:26862173   PMID:26895328   PMID:26903623   PMID:26926165   PMID:26930624   PMID:26966234   PMID:27021954   PMID:27054331   PMID:27058663   PMID:27088856   PMID:27113500   PMID:27168152  
PMID:27271267   PMID:27346580   PMID:27374340   PMID:27383066   PMID:27459195   PMID:27476975   PMID:27494874   PMID:27529127   PMID:27609640   PMID:27657167   PMID:27662578   PMID:27690690  
PMID:27773697   PMID:27791392   PMID:27796320   PMID:27875243   PMID:27879317   PMID:27889186   PMID:27893733   PMID:27912059   PMID:27923220   PMID:28017605   PMID:28065650   PMID:28112045  
PMID:28134247   PMID:28213822   PMID:28232786   PMID:28285822   PMID:28286126   PMID:28326909   PMID:28401936   PMID:28402850   PMID:28423315   PMID:28448534   PMID:28486525   PMID:28499924  
PMID:28556462   PMID:28560311   PMID:28576728   PMID:28607147   PMID:28634329   PMID:28683290   PMID:28687372   PMID:28698388   PMID:28710114   PMID:28821839   PMID:28827343   PMID:28828400  
PMID:28883509   PMID:28886335   PMID:28973913   PMID:29054877   PMID:29138421   PMID:29186676   PMID:29199069   PMID:29227248   PMID:29269828   PMID:29293562   PMID:29302035   PMID:29339832  
PMID:29362450   PMID:29386573   PMID:29447160   PMID:29463694   PMID:29463714   PMID:29478834   PMID:29490985   PMID:29491349   PMID:29518531   PMID:29533925   PMID:29540683   PMID:29555746  
PMID:29561690   PMID:29610316   PMID:29626648   PMID:29688375   PMID:29750810   PMID:29760192   PMID:29784789   PMID:29899468   PMID:29931690   PMID:29937374   PMID:29965797   PMID:29982483  
PMID:30017392   PMID:30031683   PMID:30242505   PMID:30283092   PMID:30287844   PMID:30321360   PMID:30321586   PMID:30429219   PMID:30452546   PMID:30487216   PMID:30527742   PMID:30612576  
PMID:30630934   PMID:30710088   PMID:30744968   PMID:30773466   PMID:30782483   PMID:30794439   PMID:30822304   PMID:30884411   PMID:31006590   PMID:31136603   PMID:31138685   PMID:31189119  
PMID:31189882   PMID:31211910   PMID:31260634   PMID:31263776   PMID:31296902   PMID:31308426   PMID:31358797   PMID:31390562   PMID:31420455   PMID:31428688   PMID:31522764   PMID:31687929  
PMID:31746738   PMID:31797953   PMID:31822134   PMID:31847374   PMID:31848250   PMID:31875550   PMID:31879343   PMID:31907414   PMID:31914667   PMID:31919902   PMID:31930968   PMID:32325033  
PMID:32354999   PMID:32385329   PMID:32433970   PMID:32555162   PMID:32555251   PMID:32615095   PMID:32644041   PMID:32681096   PMID:32768389   PMID:32796949   PMID:33053337   PMID:33202247  
PMID:33207207   PMID:33234609   PMID:33382840   PMID:33443219   PMID:33526663   PMID:33621249   PMID:33913482   PMID:34011974   PMID:34160105  


Genomics

Comparative Map Data
Per2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39191,343,699 - 91,387,072 (-)NCBIGRCm39mm39
GRCm39 Ensembl191,343,704 - 91,387,046 (-)Ensembl
GRCm38191,415,977 - 91,459,351 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl191,415,982 - 91,459,324 (-)EnsemblGRCm38mm10GRCm38
MGSCv37193,312,559 - 93,355,905 (-)NCBIGRCm37mm9NCBIm37
MGSCv36193,246,388 - 93,289,702 (-)NCBImm8
Celera194,353,350 - 94,396,834 (-)NCBICelera
Cytogenetic Map1DNCBI
PER2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2238,244,044 - 238,290,102 (-)EnsemblGRCh38hg38GRCh38
GRCh382238,244,038 - 238,290,102 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372239,152,685 - 239,197,251 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,817,418 - 238,861,946 (-)NCBINCBI36hg18NCBI36
Build 342238,934,685 - 238,979,092NCBI
Celera2232,865,233 - 232,909,762 (-)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2230,943,837 - 230,988,232 (-)NCBIHuRef
CHM1_12239,158,528 - 239,203,056 (-)NCBICHM1_1
Per2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2992,007,289 - 92,049,551 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl992,007,296 - 92,049,459 (-)Ensembl
Rnor_6.0998,555,154 - 98,597,362 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl998,555,169 - 98,597,359 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0998,231,202 - 98,273,371 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4990,645,342 - 90,687,509 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1990,850,110 - 90,892,278 (-)NCBI
Celera989,548,336 - 89,590,505 (-)NCBICelera
Cytogenetic Map9q36NCBI
Per2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555422,338,099 - 2,371,274 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555422,331,547 - 2,369,011 (+)NCBIChiLan1.0ChiLan1.0
PER2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B244,328,122 - 244,371,040 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B244,328,122 - 244,371,040 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B125,477,021 - 125,521,577 (-)NCBIMhudiblu_PPA_v0panPan3
PER2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12548,716,499 - 48,761,617 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2548,717,173 - 48,758,755 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2549,211,912 - 49,257,033 (-)NCBI
ROS_Cfam_1.02549,102,140 - 49,147,315 (-)NCBI
UMICH_Zoey_3.12548,977,242 - 49,022,398 (-)NCBI
UNSW_CanFamBas_1.02548,765,877 - 48,806,293 (-)NCBI
UU_Cfam_GSD_1.02548,998,242 - 49,043,270 (-)NCBI
Per2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303190,676,406 - 190,718,243 (-)NCBI
SpeTri2.0NW_004936525221,601 - 263,284 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PER2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15137,793,419 - 137,837,236 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115137,793,419 - 137,837,854 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215152,264,819 - 152,284,153 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PER2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110124,270,917 - 124,316,031 (-)NCBI
ChlSab1.1 Ensembl10124,269,543 - 124,315,904 (-)Ensembl
Vero_WHO_p1.0NW_02366604075,104,175 - 75,149,164 (+)NCBI
Per2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248473,359,174 - 3,399,584 (-)NCBI

Position Markers
PMC124275P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38191,417,344 - 91,417,845UniSTSGRCm38
MGSCv37193,313,921 - 93,314,422UniSTSGRCm37
Celera194,354,712 - 94,355,213UniSTS
Cytogenetic Map1C5UniSTS
Per2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1C5UniSTS
cM Map146.13UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134721057150318120Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134721057150318120Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134721057150318120Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139093727126517573Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
14746998Mancz1_mmandible centroid size 1 (mouse)15790219291902192Mouse
14747009Manh49_mmandible shape 49 (mouse)15790219291902192Mouse
1300746Skl1_mskeletal size (tail length) 1 (mouse)Not determined15795281891952921Mouse
1357679Egrm1_mearly growth rate, maternal effect 1 (mouse)Not determined15795281891952921Mouse
1301162Skull1_mskull morphology 1 (mouse)Not determined15795281891952921Mouse
1301444Alcw5_malcohol withdrawal 5 (mouse)Not determined15857254792572799Mouse
1301667Lxw5_mlupus BXSB x NZW 5 (mouse)Not determined15857254792572799Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162907596120601949Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163880843153681816Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167300000129800000Mouse
1302146Cocrb1_mcocaine related behavior 1 (mouse)Not determined170205811104211835Mouse
1300976Bmd19_mbone mineral density 19 (mouse)Not determined173227055108910684Mouse
4142394Mssq1_mmandible size and shape QTL 1 (mouse)Not determined73687970107688108Mouse
1301304Hrq3_mheart rate quantitative locus 3 (mouse)Not determined173687970107688108Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173716016147249632Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74477076148839837Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174952818133363199Mouse
1300821Lore1_mloss of righting induced by ethanol 1 (mouse)Not determined17557254793013355Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)176000000128600000Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)176000000148900000Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
1558928Mord2_mmodifier of retinal degeneration 2 (mouse)Not determined177146478110608345Mouse
14697706Stsl3a_mSalmonella typhimurium susceptibility locus 3a (mouse)17750000095900000Mouse
4141725Wbcq4_mwhite blood cell quantitative locus 4 (mouse)Not determined179930958113931066Mouse
12050069Nabq1_mnasal bone morphology QTL 1 (mouse)179930958113931066Mouse
13452395Leusq2_mleucocytosis susceptibility QTL 2 (mouse)180267876126458780Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782314261147249632Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182665468135687641Mouse
10412238Alpq5_malcohol preference QTL 5 (mouse)Not determined182904910116904910Mouse
12791004Aath7_maortic arch atherosclerosis 7 (mouse)182904910116904910Mouse
11667074Led2_mlate embryonic death 2 (mouse)185768306117267351Mouse
12790991Aath1_maortic arch atherosclerosis 1 (mouse)186556204120556204Mouse
4141329Mleu1_mmyeloid leukemia survival 1 (mouse)Not determined89858782123858782Mouse
15039333Nmrs1_mNAFLD-associated magnetic resonance shift 1 (mouse)189858782123858782Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:775
Count of miRNA genes:470
Interacting mature miRNAs:559
Transcripts:ENSMUST00000069620
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000069620   ⟹   ENSMUSP00000066620
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl191,343,704 - 91,387,046 (-)Ensembl
GRCm38.p6 Ensembl191,415,982 - 91,459,324 (-)Ensembl
RefSeq Acc Id: ENSMUST00000185298
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl191,375,444 - 91,377,587 (-)Ensembl
GRCm38.p6 Ensembl191,447,722 - 91,449,865 (-)Ensembl
RefSeq Acc Id: NM_011066   ⟹   NP_035196
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39191,343,704 - 91,387,050 (-)NCBI
GRCm38191,415,982 - 91,459,328 (-)NCBI
MGSCv37193,312,559 - 93,355,905 (-)RGD
Celera194,353,350 - 94,396,834 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006529249   ⟹   XP_006529312
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39191,343,699 - 91,387,072 (-)NCBI
GRCm38191,415,977 - 91,459,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006529250   ⟹   XP_006529313
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39191,343,699 - 91,373,833 (-)NCBI
GRCm38191,415,977 - 91,446,017 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004940947
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39191,343,699 - 91,387,072 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_035196   ⟸   NM_011066
- UniProtKB: O54943 (UniProtKB/Swiss-Prot),   A0A0R4J0U3 (UniProtKB/TrEMBL),   Q3TW41 (UniProtKB/TrEMBL),   Q8C8R0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006529312   ⟸   XM_006529249
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006529313   ⟸   XM_006529250
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000066620   ⟸   ENSMUST00000069620
Protein Domains
PAC   PAS   Period_C

Promoters
RGD ID:6874488
Promoter ID:EPDNEW_M695
Type:initiation region
Name:Per2_1
Description:Mus musculus period circadian clock 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38191,459,306 - 91,459,366EPDNEW
RGD ID:6846632
Promoter ID:MM_ACW:1727
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:PER2.FSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36193,320,491 - 93,320,991 (-)MPROMDB
RGD ID:6818226
Promoter ID:MM_KWN:1632
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   Spleen
Transcripts:ENSMUST00000069620,   UC007CAW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36193,355,631 - 93,356,131 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1195265 AgrOrtholog
Ensembl Genes ENSMUSG00000055866 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000066620 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000069620 ENTREZGENE, UniProtKB/TrEMBL
InterPro PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS_fold_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Period_circadian-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18627 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1195265 ENTREZGENE
NCBI Gene 18627 ENTREZGENE
Pfam PAS_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Period_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Per2 PhenoGen
PROSITE PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J0U3 ENTREZGENE, UniProtKB/TrEMBL
  O54943 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3TW41 ENTREZGENE, UniProtKB/TrEMBL
  Q7TMG5_MOUSE UniProtKB/TrEMBL
  Q8C8R0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary O54954 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-08 Per2  period circadian clock 2    period homolog 2 (Drosophila)  Symbol and/or name change 5135510 APPROVED