amino-acid anion - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	amino-acid anion	go back to main search page
Accession:	CHEBI:37022	browse the term
Synonyms:	related_synonym:	amino-acid anions
	cyclic_relationship:	is_conjugate_base_of CHEBI:33709

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Rat (832) Mouse (866) Human (839) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (10) Green Monkey (0) Naked Mole-rat (0) All
Genes (832)

4-(trimethylammonio)butanoate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

gamma-butyrobetaine hydroxylase 1

multiple interactions

[BBOX1 protein co-treated with Ketoglutaric Acids] results in increased metabolism of gamma-butyrobetaine

NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458

G

isocitrate dehydrogenase (NADP(+)) 2

multiple interactions
increases abundance

Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of gamma-butyrobetaine]

NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025

6-aminohexanoate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

decreases expression

Aminocaproic Acid results in decreased expression of A2M protein

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

folate hydrolase 1

multiple interactions

[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [isospaglumic acid binds to FOLH1 protein]

NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379

G

gastrin releasing peptide receptor

multiple interactions

[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [bombesin, Tyr(4)- binds to GRPR protein]

NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442

G

mitogen activated protein kinase 1

multiple interactions

Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein]

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions

Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein]

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

plasminogen

multiple interactions

Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein]; Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein]

NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786

G

serpin family C member 1

increases expression

Aminocaproic Acid results in increased expression of SERPINC1 protein

NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293

diminazene diaceturate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensin converting enzyme 2

increases expression
multiple interactions
increases activity

diminazene aceturate results in increased expression of ACE2 mRNA; diminazene aceturate results in increased expression of ACE2 protein
PD 123319 inhibits the reaction [diminazene aceturate results in increased expression of ACE2 protein]
diminazene aceturate results in increased activity of ACE2 protein
[Lipopolysaccharides co-treated with diminazene aceturate] results in increased expression of ACE2 mRNA; [Lipopolysaccharides co-treated with diminazene aceturate] results in increased expression of ACE2 protein; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGTR1 mRNA]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; ACE2 protein affects the reaction [diminazene aceturate promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]]

PMID:25301841 PMID:26862037 PMID:27550926 PMID:28688122 PMID:31982938

NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977

G

actin alpha 2, smooth muscle

decreases expression

diminazene aceturate results in decreased expression of ACTA2 protein

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

angiotensinogen

increases expression
multiple interactions

diminazene aceturate results in increased expression of AGT protein modified form
7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]]; ACE2 protein affects the reaction [diminazene aceturate promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]; diminazene aceturate promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]
diminazene aceturate results in increased expression of AGT protein alternative form

PMID:25301841 PMID:26862037

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

G

angiotensin II receptor, type 1a

multiple interactions

ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGTR1 mRNA]]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGTR1 mRNA]

NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946

G

amyloid beta precursor protein

affects expression

diminazene aceturate affects the expression of APP protein alternative form

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

C-C motif chemokine ligand 2

decreases expression
multiple interactions

diminazene aceturate results in decreased expression of MCP1 protein
7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]]; 7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]

PMID:26862037 PMID:29977014

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

collagen type I alpha 1 chain

decreases expression

diminazene aceturate results in decreased expression of COL1A1 protein

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

cytochrome b-245 beta chain

decreases expression

diminazene aceturate results in decreased expression of CYBB protein

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

glutamate ionotropic receptor NMDA type subunit 2B

increases phosphorylation

diminazene aceturate results in increased phosphorylation of GRIN2B protein

NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279

G

interleukin 1 beta

decreases expression

diminazene aceturate results in decreased expression of IL1B mRNA
diminazene aceturate results in decreased expression of IL1B protein

PMID:25883526 PMID:31982938

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

decreases expression
multiple interactions

diminazene aceturate results in decreased expression of IL6 protein
7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; 7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]

PMID:25883526 PMID:26862037 PMID:29977014

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

mitogen activated protein kinase 1

increases phosphorylation
multiple interactions

diminazene aceturate results in increased phosphorylation of MAPK1 protein
7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]

PMID:26862037 PMID:31982938

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 14

decreases phosphorylation

diminazene aceturate results in decreased phosphorylation of MAPK14 protein

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

G

mitogen activated protein kinase 3

increases phosphorylation
multiple interactions

diminazene aceturate results in increased phosphorylation of MAPK3 protein
7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]

PMID:26862037 PMID:31982938

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

MAS1 proto-oncogene, G protein-coupled receptor

increases expression

diminazene aceturate results in increased expression of MAS1 protein

NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709

G

neutrophil cytosolic factor 1

decreases expression

diminazene aceturate results in decreased expression of NCF1 protein

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

G

neutrophil cytosolic factor 2

decreases transport

diminazene aceturate results in decreased transport of NCF2 protein

NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277

G

NFKB inhibitor alpha

multiple interactions

7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

nitric oxide synthase 1

decreases expression

diminazene aceturate results in decreased expression of NOS1 mRNA

NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945

G

NADPH oxidase 1

decreases expression

diminazene aceturate results in decreased expression of NOX1 protein

NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236

G

RELA proto-oncogene, NF-kB subunit

decreases activity
decreases expression

diminazene aceturate results in decreased activity of RELA protein
diminazene aceturate results in decreased expression of RELA mRNA; diminazene aceturate results in decreased expression of RELA protein

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

SMAD family member 2

decreases phosphorylation

diminazene aceturate results in decreased phosphorylation of SMAD2 protein

NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323

G

SMAD family member 3

decreases phosphorylation

diminazene aceturate results in decreased phosphorylation of SMAD3 protein

NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960

G

tumor necrosis factor

decreases expression
decreases secretion

diminazene aceturate results in decreased expression of TNF mRNA; diminazene aceturate results in decreased expression of TNF protein
diminazene aceturate results in decreased secretion of TNF protein

PMID:25883526 PMID:29977014

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

ketorolac tromethamine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aralkylamine N-acetyltransferase

multiple interactions

Ketorolac Tromethamine results in decreased localization of and results in decreased activity of AANAT protein

NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801

G

catalase

multiple interactions
increases activity

Melatonin inhibits the reaction [Ketorolac Tromethamine results in increased activity of CAT protein]

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

epiregulin

increases expression

Ketorolac Tromethamine results in increased expression of EREG mRNA

NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062

G

glutathione peroxidase 1

decreases activity

Ketorolac Tromethamine results in decreased activity of GPX1 protein

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione-disulfide reductase

increases activity

Ketorolac Tromethamine results in increased activity of GSR protein

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

interleukin 24

increases expression

Ketorolac Tromethamine results in increased expression of IL24 mRNA

NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487

G

monoamine oxidase A

multiple interactions
increases activity

Melatonin inhibits the reaction [Ketorolac Tromethamine results in increased activity of MAOA protein]

NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593

G

melatonin receptor 1A

increases localization

Ketorolac Tromethamine results in increased localization of MTNR1A protein

NCBI chr16:47,144,461...47,163,919
Ensembl chr16:47,144,461...47,163,919

G

prostaglandin-endoperoxide synthase 2

increases expression

Ketorolac Tromethamine results in increased expression of PTGS2 mRNA

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

secretory leukocyte peptidase inhibitor

increases expression

Ketorolac Tromethamine results in increased expression of SLPI mRNA

NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453

G

superoxide dismutase 1

decreases activity

Ketorolac Tromethamine results in decreased activity of SOD1 protein

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

decreases activity

Ketorolac Tromethamine results in decreased activity of SOD2 protein

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

monosodium L-glutamate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ABCA1 mRNA

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily B member 4

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ABCB4 mRNA

NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202

G

ATP binding cassette subfamily C member 2

multiple interactions

[Sodium Glutamate co-treated with Bezafibrate] results in increased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily D member 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ABCD1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of ABCD1 mRNA

NCBI chr X:151,428,334...151,450,115
Ensembl chr X:151,428,578...151,450,115

G

ATP binding cassette subfamily D member 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ABCD2 mRNA

NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642

G

acetyl-CoA acyltransferase 1A

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACAA1A mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of ACAA1A mRNA

NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624

G

acetyl-Coenzyme A acyltransferase 1B

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACAA1B mRNA

NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825

G

acetyl-CoA carboxylase alpha

decreases phosphorylation
increases expression
multiple interactions

Sodium Glutamate results in decreased phosphorylation of ACACA protein
Sodium Glutamate results in increased expression of ACACA mRNA; Sodium Glutamate results in increased expression of ACACA protein
3-(4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-ylcarbonyl)thiazolidine affects the reaction [[Dietary Fats co-treated with Sodium Glutamate] affects the expression of ACACA mRNA]; [Dietary Fats co-treated with Sodium Glutamate] affects the expression of ACACA mRNA; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of ACACA mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of ACACA protein]

PMID:19724016 PMID:22415589 PMID:26670228

NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457

G

acetyl-CoA carboxylase beta

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACACB mRNA

NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655

G

acyl-CoA dehydrogenase, long chain

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of ACADL mRNA

NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220

G

acyl-CoA dehydrogenase medium chain

increases expression
multiple interactions

Sodium Glutamate results in increased expression of ACADM mRNA
SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of ACADM mRNA]

NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147

G

acyl-CoA dehydrogenase short chain

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACADS mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of ACADS mRNA; [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of ACADS mRNA

PMID:19001666 PMID:23783067

NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898

G

acyl-CoA dehydrogenase, very long chain

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACADVL mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of ACADVL mRNA

NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075

G

acetylcholinesterase

multiple interactions
increases expression

Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of ACHE protein]
Sodium Glutamate results in increased expression of ACHE mRNA

PMID:20928830 PMID:26900785

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

ATP citrate lyase

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of ACLY mRNA

NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320

G

aconitase 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACO1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of ACO1 mRNA

NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391

G

acyl-CoA thioesterase 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACOT1 mRNA

NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163

G

acyl-CoA thioesterase 12

increases expression

Sodium Glutamate results in increased expression of ACOT12 mRNA

NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536

G

acyl-CoA thioesterase 2

increases expression
multiple interactions

Sodium Glutamate results in increased expression of ACOT2 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of ACOT2 mRNA

NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245

G

acyl-CoA thioesterase 4

increases expression
multiple interactions

Sodium Glutamate results in increased expression of ACOT4 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of ACOT4 mRNA

NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917

G

acyl-CoA oxidase 1

multiple interactions

[Taurine co-treated with Sodium Glutamate] results in increased expression of ACOX1 mRNA
[Sodium Glutamate co-treated with Bezafibrate] results in increased expression of ACOX1 mRNA

PMID:21549692 PMID:26092479

NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232

G

acrosin

increases expression

Sodium Glutamate results in increased expression of ACR mRNA

NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474

G

acyl-CoA synthetase bubblegum family member 1

increases expression

Sodium Glutamate results in increased expression of ACSBG1 mRNA

NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391

G

acyl-CoA synthetase family member 2

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of ACSF2 mRNA

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 3

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of ACSL3 mRNA

NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627

G

activin A receptor type 2B

increases expression

Sodium Glutamate results in increased expression of ACVR2B mRNA

NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458

G

ADAM metallopeptidase domain 5

increases expression

Sodium Glutamate results in increased expression of ADAM5 mRNA

NCBI chr16:67,223,095...67,298,733
Ensembl chr16:67,223,143...67,298,737

G

ADAM metallopeptidase with thrombospondin type 1 motif, 7

increases expression

Sodium Glutamate results in increased expression of ADAMTS7 mRNA

NCBI chr 8:90,704,727...90,744,333
Ensembl chr 8:90,704,727...90,744,328

G

ADAMTS-like 3

decreases expression

Sodium Glutamate results in decreased expression of ADAMTSL3 mRNA

NCBI chr 1:136,288,793...136,596,986
Ensembl chr 1:136,288,793...136,596,986

G

adenylate cyclase 5

increases expression

Sodium Glutamate results in increased expression of ADCY5 mRNA

NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974

G

adhesion G protein-coupled receptor E1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ADGRE1 mRNA

NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000

G

adiponectin, C1Q and collagen domain containing

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of ADIPOQ protein
[Sodium Glutamate co-treated with Pioglitazone] results in increased expression of ADIPOQ protein; [Sodium Glutamate co-treated with Plant Extracts] results in decreased expression of ADIPOQ mRNA; Bezafibrate inhibits the reaction [Sodium Glutamate results in decreased expression of ADIPOQ protein]; fructooligosaccharide inhibits the reaction [Sodium Glutamate results in decreased expression of ADIPOQ protein]

PMID:21549692 PMID:27918843 PMID:32103741

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

adenosine A1 receptor

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of ADORA1 mRNA

NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801

G

adrenoceptor alpha 1A

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of ADRA1A mRNA

NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500

G

adrenoceptor alpha 1D

decreases expression

Sodium Glutamate results in decreased expression of ADRA1D mRNA

NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354

G

agouti related neuropeptide

decreases expression

Sodium Glutamate results in decreased expression of AGRP mRNA

NCBI chr19:33,447,992...33,481,602
Ensembl chr19:33,447,992...33,449,584

G

aryl hydrocarbon receptor

increases expression

Sodium Glutamate results in increased expression of AHR mRNA

PMID:19001666 PMID:22078008

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

apoptosis inducing factor, mitochondria associated 3

increases expression

Sodium Glutamate results in increased expression of AIFM3 mRNA

NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248

G

aldo-keto reductase family 1 member A1

increases expression

Sodium Glutamate results in increased expression of AKR1A1 mRNA; Sodium Glutamate results in increased expression of AKR1A1 protein

NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674

G

aldo-keto reductase family 1, member C1

increases expression

Sodium Glutamate results in increased expression of AKR1C6 mRNA

NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326

G

AKT serine/threonine kinase 1

decreases phosphorylation
increases expression
multiple interactions

Sodium Glutamate results in decreased phosphorylation of AKT1 protein
Sodium Glutamate results in increased expression of AKT1 protein
Tea inhibits the reaction [Sodium Glutamate results in decreased phosphorylation of AKT1 protein]

PMID:29679905 PMID:36732937

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aldehyde dehydrogenase 1 family, member A1

increases expression
multiple interactions

Sodium Glutamate results in increased expression of ALDH1A1 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of ALDH1A1 mRNA

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member A3

increases expression

Sodium Glutamate results in increased expression of ALDH1A3 mRNA

NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436

G

aldehyde dehydrogenase 1 family, member L2

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of ALDH1L2 mRNA

NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776

G

aldehyde dehydrogenase 3 family, member A1

decreases expression

Sodium Glutamate results in decreased expression of ALDH3A1 mRNA

NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681

G

ALG6, alpha-1,3-glucosyltransferase

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of ALG6 mRNA

NCBI chr 5:114,404,972...114,454,440
Ensembl chr 5:114,405,010...114,454,439

G

arachidonate 15-lipoxygenase

multiple interactions
increases expression

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ALOX15 mRNA; [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of ALOX15 mRNA
Sodium Glutamate results in increased expression of ALOX15 mRNA

PMID:20111022 PMID:23783067

NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874

G

autophagy and beclin 1 regulator 1

increases expression

Sodium Glutamate results in increased expression of AMBRA1 mRNA

NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221

G

annexin A1

decreases expression

Sodium Glutamate results in decreased expression of ANXA1 mRNA

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

adaptor related protein complex 1 subunit mu 2

increases expression

Sodium Glutamate results in increased expression of AP1M2 mRNA

NCBI chr 8:19,838,579...19,856,560
Ensembl chr 8:19,838,580...19,856,482

G

amyloid beta precursor protein binding family B member 1

increases expression

Sodium Glutamate results in increased expression of APBB1 mRNA

NCBI chr 1:159,896,889...159,920,505
Ensembl chr 1:159,896,880...159,920,627

G

adipocyte plasma membrane associated protein

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of APMAP mRNA

NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341

G

apolipoprotein C2

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of APOC2 mRNA

NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476

G

apolipoprotein D

increases expression
multiple interactions

Sodium Glutamate results in increased expression of APOD mRNA
[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of APOD mRNA

PMID:19001666 PMID:20111022

NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305

G

apolipoprotein E

increases expression
multiple interactions

Sodium Glutamate results in increased expression of APOE mRNA; Sodium Glutamate results in increased expression of APOE protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Sodium Glutamate results in increased expression of APOE mRNA]

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

increases expression

Sodium Glutamate results in increased expression of ARAP3 mRNA

NCBI chr18:29,806,214...29,834,217
Ensembl chr18:29,807,536...29,833,555

G

activity-regulated cytoskeleton-associated protein

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of ARC mRNA

NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378

G

arginase 2

increases expression

Sodium Glutamate results in increased expression of ARG2 mRNA

NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378

G

Rho guanine nucleotide exchange factor 1

increases expression

Sodium Glutamate results in increased expression of ARHGEF1 mRNA

NCBI chr 1:80,499,026...80,520,954
Ensembl chr 1:80,499,131...80,520,953

G

arylsulfatase B

decreases expression

Sodium Glutamate results in decreased expression of ARSB mRNA

NCBI chr 2:25,002,210...25,162,675
Ensembl chr 2:25,002,346...25,162,671

G

ATPase Na+/K+ transporting subunit alpha 3

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of ATP1A3 mRNA

NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918

G

ATPase plasma membrane Ca2+ transporting 3

increases expression

Sodium Glutamate results in increased expression of ATP2B3 mRNA

NCBI chr X:151,216,483...151,289,069
Ensembl chr X:151,216,507...151,286,775

G

ATPase copper transporting beta

increases expression

Sodium Glutamate results in increased expression of ATP7B mRNA

NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636

G

axin 1

decreases expression

Sodium Glutamate results in decreased expression of AXIN1 mRNA

NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615

G

BMP and activin membrane-bound inhibitor

decreases expression

Sodium Glutamate results in decreased expression of BAMBI mRNA

NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of BAX mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of BAX mRNA
Sodium Glutamate results in increased expression of BAX mRNA
Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of BAX mRNA]

PMID:23783067 PMID:26900785

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BRCA2 and CDKN1A interacting protein

increases expression
multiple interactions

Sodium Glutamate results in increased expression of BCCIP mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of BCCIP mRNA

NCBI chr 1:188,512,544...188,524,957
Ensembl chr 1:188,512,367...188,524,958

G

butyrylcholinesterase

increases activity
multiple interactions

Sodium Glutamate results in increased activity of BCHE protein
Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of BCHE protein]

NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148

G

BCL2, apoptosis regulator

multiple interactions
increases expression
decreases expression

[Homocysteine co-treated with Sodium Glutamate] affects the expression of BCL2 mRNA; [Homocysteine co-treated with Sodium Glutamate] affects the expression of BCL2 protein; Folic Acid affects the reaction [[Homocysteine co-treated with Sodium Glutamate] affects the expression of BCL2 mRNA]; Folic Acid affects the reaction [[Homocysteine co-treated with Sodium Glutamate] affects the expression of BCL2 protein]; Lycopene inhibits the reaction [Sodium Glutamate results in decreased expression of BCL2 mRNA]
SB 203580 inhibits the reaction [Sodium Glutamate results in increased expression of BCL2 mRNA]

PMID:16782274 PMID:22169520 PMID:26900785

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 11

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of BCL2L11 mRNA
Sodium Glutamate results in increased expression of BCL2L11 mRNA

NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068

G

BEN domain containing 3

increases expression

Sodium Glutamate results in increased expression of BEND3 mRNA

NCBI chr20:46,980,246...47,017,059
Ensembl chr20:46,979,831...47,014,671

G

bridging integrator 3

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of BIN3 mRNA

NCBI chr15:45,173,725...45,212,607
Ensembl chr15:45,173,732...45,212,604

G

BMI1 proto-oncogene, polycomb ring finger

multiple interactions
increases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of BMI1 mRNA
Sodium Glutamate results in increased expression of BMI1 mRNA

NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690

G

BCL2 interacting protein 5

increases expression

Sodium Glutamate results in increased expression of BNIP5 mRNA

NCBI chr20:6,957,736...6,975,062
Ensembl chr20:6,956,201...6,975,091

G

BOP1 ribosomal biogenesis factor

increases expression

Sodium Glutamate results in increased expression of BOP1 mRNA

NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931

G

BR serine/threonine kinase 2

increases expression

Sodium Glutamate results in increased expression of BRSK2 mRNA

NCBI chr 1:197,035,505...197,088,624
Ensembl chr 1:197,035,633...197,088,092

G

basic leucine zipper and W2 domains 2

increases expression

Sodium Glutamate results in increased expression of BZW2 mRNA

NCBI chr 6:52,828,069...52,888,599
Ensembl chr 6:52,827,661...52,888,628

G

C1q and TNF related 1

decreases expression

Sodium Glutamate results in decreased expression of C1QTNF1 mRNA

NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660

G

calcium binding protein 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CABP2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CABP2 mRNA

NCBI chr 1:201,374,649...201,380,469
Ensembl chr 1:201,375,276...201,380,469

G

calcium voltage-gated channel subunit alpha1 A

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNA1A mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CACNA1A mRNA

NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225

G

calcium voltage-gated channel subunit alpha1 I

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNA1I mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CACNA1I mRNA

NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688

G

calcium voltage-gated channel auxiliary subunit alpha2delta 4

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNA2D4 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CACNA2D4 mRNA

NCBI chr 4:152,408,588...152,521,478
Ensembl chr 4:152,408,657...152,521,268

G

calcium voltage-gated channel auxiliary subunit beta 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNB2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CACNB2 mRNA

NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106

G

calcium voltage-gated channel auxiliary subunit gamma 4

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNG4 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CACNG4 mRNA

NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126

G

calcium voltage-gated channel auxiliary subunit gamma 8

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNG8 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CACNG8 mRNA

NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089

G

calcium homeostasis modulator family member 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CALHM2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CALHM2 mRNA

NCBI chr 1:246,022,324...246,028,050
Ensembl chr 1:246,022,324...246,028,218

G

calreticulin

decreases expression

Sodium Glutamate results in decreased expression of CALR mRNA

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

G

calreticulin 3

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CALR3 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CALR3 mRNA

NCBI chr16:17,396,064...17,423,166
Ensembl chr16:17,396,247...17,423,015

G

calcium/calmodulin-dependent protein kinase II alpha

increases expression

Sodium Glutamate results in increased expression of CAMK2A mRNA

NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994

G

calcium/calmodulin-dependent protein kinase II beta

increases expression

Sodium Glutamate results in increased expression of CAMK2B mRNA

NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994

G

calcium modulating ligand

decreases expression

Sodium Glutamate results in decreased expression of CAMLG mRNA

NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552

G

calcium activated nucleotidase 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CANT1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CANT1 mRNA

NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109

G

calcyphosine 2

increases expression

Sodium Glutamate results in increased expression of CAPS2 mRNA

NCBI chr 7:47,580,636...47,641,598
Ensembl chr 7:47,581,137...47,639,229

G

carbonic anhydrase 2

decreases expression

Sodium Glutamate results in decreased expression of CAR2 mRNA

NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818

G

carbonic anhydrase 5B

decreases expression

Sodium Glutamate results in decreased expression of CAR5B mRNA

NCBI chr X:30,474,697...30,534,797
Ensembl chr X:30,474,784...30,533,837

G

caspase 6

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of CASP6 mRNA

NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502

G

caspase 9

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CASP9 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CASP9 mRNA

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

decreases expression
increases expression
multiple interactions
increases activity
decreases activity

Sodium Glutamate results in decreased expression of CAT mRNA
Sodium Glutamate results in increased expression of CAT mRNA; Sodium Glutamate results in increased expression of CAT protein
[Plant Extracts co-treated with Sodium Glutamate] results in increased activity of CAT protein; Sodium Glutamate results in increased expression of and results in decreased activity of CAT protein; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of CAT mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of CAT protein]; Tea inhibits the reaction [Sodium Glutamate results in decreased activity of CAT protein]
Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of CAT mRNA]

PMID:19724016 PMID:25473020 PMID:26319613 PMID:26900785 PMID:29679905 More...

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

cation channel, sperm associated 1

increases expression

Sodium Glutamate results in increased expression of CATSPER1 mRNA

NCBI chr 1:202,643,009...202,652,059
Ensembl chr 1:202,643,038...202,651,824

G

cation channel, sperm associated 2

increases expression

Sodium Glutamate results in increased expression of CATSPER2 mRNA

NCBI chr 3:108,368,654...108,389,380
Ensembl chr 3:108,368,668...108,388,050

G

carbonyl reductase 1

increases activity

Sodium Glutamate results in increased activity of CBR1 protein

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

coiled-coil domain containing 138

increases expression

Sodium Glutamate results in increased expression of CCDC138 mRNA

NCBI chr20:26,493,624...26,572,367
Ensembl chr20:26,495,235...26,572,376

G

coiled-coil domain containing 30

increases expression

Sodium Glutamate results in increased expression of CCDC30 mRNA

NCBI chr 5:132,926,767...133,019,635
Ensembl chr 5:132,926,615...133,019,659

G

coiled-coil domain 39 molecular ruler complex subunit

increases expression

Sodium Glutamate results in increased expression of CCDC39 mRNA

NCBI chr 2:116,665,651...116,703,354
Ensembl chr 2:116,665,261...116,703,350

G

coiled-coil domain containing 60

increases expression

Sodium Glutamate results in increased expression of CCDC60 mRNA

NCBI chr12:40,314,687...40,480,338
Ensembl chr12:40,314,713...40,480,225

G

C-C motif chemokine ligand 2

multiple interactions
decreases expression
increases expression

[Fats, Unsaturated co-treated with Sodium Glutamate] results in increased expression of CCL2 protein; [Sodium Glutamate co-treated with Aspartame] inhibits the reaction [Fats, Unsaturated results in increased expression of CCL2 protein]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of CCL2 mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of CCL2 protein]
Sodium Glutamate results in decreased expression of CCL2 mRNA
Sodium Glutamate results in increased expression of CCL2 mRNA; Sodium Glutamate results in increased expression of CCL2 protein

PMID:19724016 PMID:20111022 PMID:23783067

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 21

multiple interactions
increases expression

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of CCL21A mRNA
Sodium Glutamate results in increased expression of CCL21A mRNA

NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686

G

cyclin D2

affects expression
multiple interactions

Sodium Glutamate affects the expression of CCND2 mRNA
[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CCND2 mRNA

PMID:19001666 PMID:28954212

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

cyclin D3

decreases expression
increases expression
multiple interactions

Sodium Glutamate results in decreased expression of CCND3 mRNA
Sodium Glutamate results in increased expression of CCND3 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of CCND3 mRNA

PMID:20111022 PMID:22078008

NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371

G

cyclin G1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CCNG1 mRNA

NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641

G

Cd80 molecule

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of CD80 mRNA

NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030

G

Cd81 molecule

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of CD81 mRNA

NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660

G

CD86 molecule

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of CD86 mRNA

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

G

CUB domain containing protein 2

increases expression

Sodium Glutamate results in increased expression of CDCP2 mRNA

NCBI chr 5:121,877,581...121,894,203
Ensembl chr 5:121,877,581...121,894,203

G

cadherin 1

increases expression

Sodium Glutamate results in increased expression of CDH1 mRNA

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cyclin-dependent kinase 5

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CDK5 mRNA

NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112

G

cyclin-dependent kinase inhibitor 1A

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] affects the expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CDKN1B mRNA

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

cyclin-dependent kinase inhibitor 1C

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of CDKN1C mRNA

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 2A

decreases expression
increases expression

Sodium Glutamate results in decreased expression of CDKN2A mRNA; Sodium Glutamate results in decreased expression of CDKN2A protein
Sodium Glutamate results in increased expression of CDKN2A mRNA

PMID:22078008 PMID:28954212

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

cyclin-dependent kinase inhibitor 2B

increases expression
multiple interactions

Sodium Glutamate results in increased expression of CDKN2B mRNA
[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CDKN2B mRNA

PMID:19001666 PMID:28954212

NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050

G

cyclin dependent kinase inhibitor 2D

decreases expression

Sodium Glutamate results in decreased expression of CDKN2D mRNA

NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674

G

CDP-diacylglycerol synthase 1

increases expression

Sodium Glutamate results in increased expression of CDS1 mRNA

NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681

G

centrosomal protein 76

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of CEP76 mRNA

NCBI chr18:61,174,514...61,208,512
Ensembl chr18:61,178,310...61,208,504

G

complement factor D

multiple interactions
decreases activity
decreases expression

[Caffeine co-treated with Ephedrine] affects the reaction [Sodium Glutamate results in decreased expression of CFD mRNA]; [Caffeine co-treated with Ephedrine] affects the reaction [Sodium Glutamate results in decreased expression of CFD protein]; [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CFD mRNA
Sodium Glutamate results in decreased activity of CFD protein
Sodium Glutamate results in decreased expression of CFD mRNA; Sodium Glutamate results in decreased expression of CFD protein

PMID:2307116 PMID:2734615 PMID:2798420 PMID:3299706 PMID:7961801 More...

NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053

G

glycoprotein hormones, alpha polypeptide

multiple interactions

Sodium Glutamate inhibits the reaction [CGA protein results in increased secretion of 7-hydroxyprogesterone]; Sodium Glutamate inhibits the reaction [CGA protein results in increased secretion of Androstenedione]

NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191

G

calcium homeostasis endoplasmic reticulum protein

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CHERP mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CHERP mRNA

NCBI chr16:17,367,455...17,380,507
Ensembl chr16:17,367,455...17,380,507

G

charged multivesicular body protein 5

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of CHMP5 mRNA

NCBI chr 5:56,081,385...56,098,529
Ensembl chr 5:56,081,343...56,098,529

G

cholinergic receptor nicotinic beta 3 subunit

increases expression

Sodium Glutamate results in increased expression of CHRNB3 mRNA

NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360

G

carbohydrate sulfotransferase 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CHST1 mRNA

NCBI chr 3:78,552,059...78,574,740
Ensembl chr 3:78,548,525...78,574,883

G

component of inhibitor of nuclear factor kappa B kinase complex

decreases expression
increases phosphorylation
multiple interactions

Sodium Glutamate results in decreased expression of CHUK mRNA
Sodium Glutamate results in increased phosphorylation of CHUK protein
Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of CHUK protein]

PMID:19800637 PMID:28954212

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

G

cytosolic iron-sulfur assembly component 2A

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of CIAO2A mRNA

NCBI chr 8:66,670,533...66,682,455
Ensembl chr 8:66,670,483...66,682,455

G

circadian associated repressor of transcription

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CIART mRNA

NCBI chr 2:183,419,819...183,424,845
Ensembl chr 2:183,419,819...183,423,313

G

cell death-inducing DFFA-like effector a

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CIDEA mRNA

NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481

G

cell death-inducing DFFA-like effector c

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CIDEC mRNA
Sodium Glutamate results in increased expression of CIDEC mRNA

NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173

G

creatine kinase B

increases activity
multiple interactions

Sodium Glutamate results in increased activity of CKB protein
Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CKB protein]

NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315

G

claspin

increases expression

Sodium Glutamate results in increased expression of CLSPN mRNA

NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034

G

calsyntenin 3

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CLSTN3 mRNA

NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769

G

C-x(9)-C motif containing 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CMC1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CMC1 mRNA

NCBI chr 8:117,798,036...117,900,458
Ensembl chr 8:117,798,945...117,900,462

G

chemerin chemokine-like receptor 1

decreases expression

Sodium Glutamate results in decreased expression of CMKLR1 mRNA

NCBI chr12:42,974,462...43,027,321
Ensembl chr12:42,974,410...43,028,129

G

cornichon family member 4

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of CNIH4 mRNA

NCBI chr13:92,910,315...92,926,428
Ensembl chr13:92,910,315...92,927,853

G

cyclin and CBS domain divalent metal cation transport mediator 3

decreases expression

Sodium Glutamate results in decreased expression of CNNM3 mRNA

NCBI chr 9:38,755,374...38,770,740
Ensembl chr 9:38,755,390...38,770,740

G

cytochrome c oxidase assembly factor 7

increases expression

Sodium Glutamate results in increased expression of COA7 mRNA

NCBI chr 5:123,069,356...123,080,942
Ensembl chr 5:123,069,371...123,080,199

G

collagen type I alpha 1 chain

decreases expression

Sodium Glutamate results in decreased expression of COL1A1 mRNA

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type III alpha 1 chain

decreases expression

Sodium Glutamate results in decreased expression of COL3A1 mRNA

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

cartilage oligomeric matrix protein

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of COMP mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of COMP mRNA

NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845

G

catechol-O-methyltransferase

increases expression

Sodium Glutamate results in increased expression of COMT mRNA

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

COP9 signalosome subunit 3

multiple interactions
increases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of COPS3 mRNA
Sodium Glutamate results in increased expression of COPS3 mRNA

NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597

G

coenzyme Q10B

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of COQ10B mRNA

NCBI chr 9:56,553,751...56,573,671
Ensembl chr 9:56,553,758...56,573,663

G

coactosin-like F-actin binding protein 1

decreases expression

Sodium Glutamate results in decreased expression of COTL1 mRNA

NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689

G

cytochrome c oxidase copper chaperone COX11

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of COX11 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of COX11 mRNA

NCBI chr10:75,458,735...75,465,322
Ensembl chr10:75,458,749...75,465,322

G

cytochrome c oxidase subunit 4i2

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of COX4I2 mRNA

NCBI chr 3:141,228,443...141,239,337
Ensembl chr 3:141,228,443...141,239,331

G

cytochrome c oxidase subunit 7A1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of COX7A1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of COX7A1 mRNA

NCBI chr 1:85,422,162...85,447,530
Ensembl chr 1:85,441,871...85,445,151

G

cytochrome c oxidase subunit 7A2 like

increases expression

Sodium Glutamate results in increased expression of COX7A2L mRNA

NCBI chr 6:11,184,064...11,198,287
Ensembl chr 6:11,184,285...11,198,273

G

copine 2

increases expression

Sodium Glutamate results in increased expression of CPNE2 mRNA

NCBI chr19:10,434,277...10,472,146
Ensembl chr19:10,434,277...10,471,820

G

carnitine palmitoyltransferase 1A

multiple interactions
decreases expression

Taurine inhibits the reaction [Sodium Glutamate results in decreased expression of CPT1A mRNA]
[Sodium Glutamate co-treated with Bezafibrate] results in increased expression of CPT1A mRNA

PMID:21549692 PMID:26092479

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 1B

multiple interactions
increases expression

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CPT1B mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of CPT1B mRNA; [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CPT1B mRNA; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of CPT1B mRNA]

PMID:19001666 PMID:19724016 PMID:23783067

NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404

G

carnitine palmitoyltransferase 1c

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CPT1C mRNA

NCBI chr 1:95,442,814...95,457,347
Ensembl chr 1:95,442,817...95,457,342

G

carnitine palmitoyltransferase 2

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CPT2 mRNA

NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095

G

carboxypeptidase Z

increases expression

Sodium Glutamate results in increased expression of CPZ mRNA

NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945

G

carnitine O-acetyltransferase

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CRAT mRNA

NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255

G

cAMP responsive element binding protein 1

affects expression
increases expression
multiple interactions
decreases phosphorylation

Sodium Glutamate affects the expression of CREB1 mRNA
Sodium Glutamate results in increased expression of CREB1 mRNA
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Sodium Glutamate results in increased expression of CREB1 mRNA]; Dizocilpine Maleate inhibits the reaction [Sodium Glutamate results in increased expression of CREB1 mRNA]
[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CREB1 mRNA
Sodium Glutamate results in decreased phosphorylation of CREB1 protein

PMID:23783067 PMID:28954212 PMID:31981724

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

CREB binding protein

decreases expression

Sodium Glutamate results in decreased expression of CREBBP mRNA

NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888

G

cysteine-rich with EGF-like domains 2

multiple interactions
decreases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of CRELD2 mRNA
Sodium Glutamate results in decreased expression of CRELD2 mRNA

NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543

G

corticotropin releasing hormone

decreases expression

Sodium Glutamate results in decreased expression of CRH mRNA

NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919

G

cytotoxic and regulatory T cell molecule

increases expression

Sodium Glutamate results in increased expression of CRTAM mRNA

NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343

G

cartilage associated protein

decreases expression

Sodium Glutamate results in decreased expression of CRTAP mRNA

NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631

G

cryptochrome circadian regulator 1

decreases expression

Sodium Glutamate results in decreased expression of CRY1 mRNA

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

crystallin beta-gamma domain containing 1

increases expression

Sodium Glutamate results in increased expression of CRYBG1 mRNA

NCBI chr20:47,425,030...47,496,918
Ensembl chr20:47,426,183...47,621,392

G

colony stimulating factor 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CSF1 mRNA

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

colony stimulating factor 2 receptor subunit beta

multiple interactions

[EPO protein co-treated with Sodium Glutamate] affects the expression of CSF2RB mRNA

NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157

G

chymotrypsin-like

increases expression

Sodium Glutamate results in increased expression of CTRB1 mRNA

NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626

G

C-X3-C motif chemokine receptor 1

increases expression

Sodium Glutamate results in increased expression of CX3CR1 mRNA

NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014

G

C-X-C motif chemokine ligand 9

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CXCL9 mRNA

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

G

cytochrome b5 type B

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CYB5B mRNA

NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions

[Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP1A2 mRNA; [Sodium Glutamate co-treated with Tea] affects the expression of CYP1A2 mRNA

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 20, subfamily a, polypeptide 1

increases expression

Sodium Glutamate results in increased expression of CYP20A1 mRNA

NCBI chr 9:61,755,804...61,805,123
Ensembl chr 9:61,755,790...61,805,123

G

cytochrome P450, family 2, subfamily a, polypeptide 1

multiple interactions

Sodium Glutamate results in increased expression of and results in increased activity of CYP2A1 protein

NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887

G

cytochrome P450, family 2, subfamily a, polypeptide 2

multiple interactions

Sodium Glutamate results in decreased expression of and results in decreased activity of CYP2A2 protein

NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions
increases expression

[Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP2B10 mRNA; [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of CYP2B10 mRNA; [Sodium Glutamate co-treated with Tea] affects the expression of CYP2B10 mRNA; [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of CYP2B10 mRNA
Sodium Glutamate results in increased expression of CYP2B10 mRNA

PMID:19001666 PMID:20111022 PMID:25663641

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, subfamily 2, polypeptide 11

multiple interactions
decreases expression
decreases activity
increases expression

[Sodium Glutamate co-treated with GH1 protein] results in decreased splicing of CYP2C11 mRNA; [Sodium Glutamate co-treated with GH1 protein] results in increased splicing of CYP2C11 mRNA; [Sodium Glutamate co-treated with GH1 protein] results in increased ubiquitination of CYP2C11 protein; GH1 protein affects the reaction [Sodium Glutamate results in decreased activity of CYP2C11 protein]; GH1 protein affects the reaction [Sodium Glutamate results in decreased expression of CYP2C11 mRNA]; GH1 protein inhibits the reaction [Sodium Glutamate results in decreased activity of CYP2C11 protein]; Sodium Glutamate inhibits the reaction [GH1 protein results in increased expression of CYP2C11 protein]; Sodium Glutamate results in increased expression of and affects the splicing of CYP2C11 mRNA alternative form; Sodium Glutamate results in increased expression of and results in decreased splicing of CYP2C11 mRNA; Sodium Glutamate results in increased expression of and results in increased activity of CYP2C11 protein
Sodium Glutamate results in increased expression of CYP2C11 mRNA; Sodium Glutamate results in increased expression of CYP2C11 mRNA alternative form; Sodium Glutamate results in increased expression of CYP2C11 protein

PMID:7476908 PMID:7965769 PMID:8496838 PMID:11089541 PMID:25697375

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 2, subfamily c, polypeptide 12

increases expression

Sodium Glutamate results in increased expression of CYP2C12 mRNA; Sodium Glutamate results in increased expression of CYP2C12 protein

NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019

G

cytochrome P450, family 2, subfamily c, polypeptide 24

multiple interactions
increases expression

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of CYP2C55 mRNA
Sodium Glutamate results in increased expression of CYP2C55 mRNA

PMID:19001666 PMID:20111022

NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238

G

cytochrome P450, family 2, subfamily C, polypeptide 6

multiple interactions
increases expression

[Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP2C29 mRNA
Sodium Glutamate results in increased expression of CYP2C29 mRNA

PMID:20111022 PMID:25663641

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily c, polypeptide 66

multiple interactions
increases expression

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of CYP2C66 mRNA
Sodium Glutamate results in increased expression of CYP2C66 mRNA

NCBI chr 1:237,078,517...237,169,841
Ensembl chr 1:237,078,517...237,169,650

G

cytochrome P450, family 2, subfamily d, polypeptide 4

multiple interactions

[Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP2D22 mRNA; [Sodium Glutamate co-treated with Tea] affects the expression of CYP2D22 mRNA

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

[Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP2E1 mRNA; [Sodium Glutamate co-treated with Tea] affects the expression of CYP2E1 mRNA

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions

GH1 protein inhibits the reaction [Sodium Glutamate results in decreased expression of and results in decreased activity of CYP3A2 protein]; Sodium Glutamate results in decreased expression of and results in decreased activity of CYP3A2 protein

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 9

multiple interactions
decreases expression

[Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP3A13 mRNA; [Sodium Glutamate co-treated with Tea] affects the expression of CYP3A13 mRNA
Sodium Glutamate results in decreased expression of CYP3A9 mRNA

PMID:20928830 PMID:25663641

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450, family 46, subfamily a, polypeptide 1

multiple interactions
increases expression

6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Sodium Glutamate results in increased expression of CYP46A1 mRNA]; Dizocilpine Maleate inhibits the reaction [Sodium Glutamate results in increased expression of CYP46A1 mRNA]; Dizocilpine Maleate inhibits the reaction [Sodium Glutamate results in increased expression of CYP46A1 protein]
Sodium Glutamate results in increased expression of CYP46A1 mRNA; Sodium Glutamate results in increased expression of CYP46A1 protein

NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760

G

cytochrome P450 family 7 subfamily A member 1

multiple interactions
increases expression

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of CYP7A1 mRNA
Sodium Glutamate results in increased expression of CYP7A1 mRNA

PMID:19001666 PMID:20111022

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

G

dysbindin domain containing 1

increases expression

Sodium Glutamate results in increased expression of DBNDD1 mRNA

NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444

G

dynactin subunit 1

increases expression

Sodium Glutamate results in increased expression of DCTN1 mRNA

NCBI chr 4:115,671,024...115,703,824
Ensembl chr 4:115,661,638...115,703,815

G

dicarbonyl and L-xylulose reductase

increases expression

Sodium Glutamate results in increased expression of DCXR mRNA

NCBI chr10:106,006,404...106,008,293

G

DEAD-box helicase 19B

increases expression

Sodium Glutamate results in increased expression of DDX19B mRNA

NCBI chr19:38,968,215...38,998,907
Ensembl chr19:38,968,215...38,997,259

G

defensin beta 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of DEFB1 mRNA

NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604

G

DEP domain containing 1B

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of DEPDC1B mRNA

NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779

G

D-glutamate cyclase

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of DGLUCY mRNA

NCBI chr 6:120,055,480...120,130,910
Ensembl chr 6:120,055,460...120,130,910

G

diablo, IAP-binding mitochondrial protein

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of DIABLO mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of DIABLO mRNA

NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387

G

delta like non-canonical Notch ligand 1

decreases expression

Sodium Glutamate results in decreased expression of DLK1 mRNA

NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522

G

distal-less homeobox 5

increases expression

Sodium Glutamate results in increased expression of DLX5 mRNA

NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407

G

DnaJ heat shock protein family (Hsp40) member A1

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of DNAJA1 mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of DNAJA1 mRNA

NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967

G

DnaJ heat shock protein family (Hsp40) member C27

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of DNAJC27 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of DNAJC27 mRNA

NCBI chr 6:27,068,713...27,098,449
Ensembl chr 6:27,068,686...27,098,449

G

dynein, axonemal, light chain 1

increases expression

Sodium Glutamate results in increased expression of DNAL1 mRNA

NCBI chr 6:103,747,801...103,779,015
Ensembl chr 6:103,747,753...103,778,878

G

dolichyldiphosphatase 1

decreases expression

Sodium Glutamate results in decreased expression of DOLPP1 mRNA

NCBI chr 3:13,666,000...13,674,312
Ensembl chr 3:13,665,823...13,674,311

G

dihydropyrimidinase

increases expression

Sodium Glutamate results in increased expression of DPYS mRNA

NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231

G

desmoplakin

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of DSP mRNA
Sodium Glutamate results in increased expression of DSP mRNA

NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800

G

dual oxidase 2

increases expression

Sodium Glutamate results in increased expression of DUOX2 mRNA

NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902

G

dynein light chain Tctex-type 3

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of DYNLT3 mRNA

NCBI chr X:13,327,933...13,337,139
Ensembl chr X:13,327,892...13,337,139

G

DAZ interacting zinc finger protein 1

increases expression

Sodium Glutamate results in increased expression of DZIP1 mRNA

NCBI chr15:95,956,329...96,009,994
Ensembl chr15:95,956,398...96,010,066

G

E2F transcription factor 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of E2F1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of E2F1 mRNA

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

E2F transcription factor 3

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of E2F3 mRNA

NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253

G

endothelin converting enzyme-like 1

increases expression

Sodium Glutamate results in increased expression of ECEL1 mRNA

NCBI chr 9:87,819,516...87,829,154
Ensembl chr 9:87,816,718...87,826,675

G

enoyl-CoA hydratase 1

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of ECH1 mRNA

NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795

G

ephrin A1

increases expression

Sodium Glutamate results in increased expression of EFNA1 mRNA

NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866

G

epidermal growth factor receptor

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of EGFR mRNA
[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of EGFR mRNA

PMID:19001666 PMID:28954212

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of EHHADH mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of EHHADH mRNA; [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of EHHADH mRNA

PMID:19001666 PMID:23783067

NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188

G

eukaryotic translation initiation factor 2 alpha kinase 4

multiple interactions
increases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of EIF2AK4 mRNA
Sodium Glutamate results in increased expression of EIF2AK4 mRNA

NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630

G

eukaryotic translation initiation factor 4E binding protein 2

decreases expression

Sodium Glutamate results in decreased expression of EIF4EBP2 mRNA

NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,382,668...29,399,946

G

elastase, neutrophil expressed

increases expression

Sodium Glutamate results in increased expression of ELANE mRNA

NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100

G

engulfment and cell motility 3

increases expression

Sodium Glutamate results in increased expression of ELMO3 mRNA

NCBI chr19:33,181,952...33,186,399
Ensembl chr19:33,182,036...33,186,410

G

ELOVL fatty acid elongase 6

multiple interactions

3-(4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-ylcarbonyl)thiazolidine affects the reaction [[Dietary Fats co-treated with Sodium Glutamate] affects the expression of ELOVL6 mRNA]; [Dietary Fats co-treated with Sodium Glutamate] affects the expression of ELOVL6 mRNA

NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186

G

elastin microfibril interfacer 1

increases expression

Sodium Glutamate results in increased expression of EMILIN1 mRNA

NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698

G

epithelial membrane protein 1

multiple interactions
decreases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of EMP1 mRNA
Sodium Glutamate results in decreased expression of EMP1 mRNA

NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904

G

epoxide hydrolase 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of EPHX2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of EPHX2 mRNA

NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615

G

erythropoietin

increases expression
multiple interactions
affects expression

Sodium Glutamate results in increased expression of EPO mRNA
[EPO protein co-treated with Sodium Glutamate] affects the expression of CSF2RB mRNA; [EPO protein co-treated with Sodium Glutamate] results in increased expression of EPO protein; [EPO protein co-treated with Sodium Glutamate] results in increased expression of EPOR mRNA; [EPO protein co-treated with Sodium Glutamate] results in increased expression of EPOR protein; EPO protein inhibits the reaction [Sodium Glutamate results in increased expression of EPO mRNA]
Sodium Glutamate affects the expression of EPO protein

NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946

G

erythropoietin receptor

multiple interactions
increases expression

[EPO protein co-treated with Sodium Glutamate] results in increased expression of EPOR mRNA; [EPO protein co-treated with Sodium Glutamate] results in increased expression of EPOR protein
Sodium Glutamate results in increased expression of EPOR protein

NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257

G

erb-b2 receptor tyrosine kinase 3

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of ERBB3 mRNA
Sodium Glutamate results in increased expression of ERBB3 mRNA

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

G

ER lipid raft associated 1

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of ERLIN1 mRNA

NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394

G

estrogen-related receptor beta

increases expression

Sodium Glutamate results in increased expression of ESRRB mRNA

NCBI chr 6:106,007,701...106,163,136
Ensembl chr 6:106,008,095...106,160,791

G

exosome component 8

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of EXOSC8 mRNA

NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928

G

enhancer of zeste 1 polycomb repressive complex 2 subunit

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in decreased expression of EZH1 mRNA

NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921

G

FA core complex associated protein 24

decreases expression

Sodium Glutamate results in decreased expression of FAAP24 mRNA

NCBI chr 1:88,051,523...88,057,997
Ensembl chr 1:88,051,911...88,057,989

G

fatty acid binding protein 5

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of FABP5 mRNA

NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773

G

fatty acid desaturase 1

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of FADS1 mRNA
Sodium Glutamate results in increased expression of FADS1 mRNA

NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734

G

fatty acid desaturase 2

increases expression

Sodium Glutamate results in increased expression of FADS2 mRNA

NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789

G

Fas apoptotic inhibitory molecule

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of FAIM mRNA

NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562

G

Fas apoptotic inhibitory molecule 2

increases expression

Sodium Glutamate results in increased expression of FAIM2 mRNA

NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168

G

family with sequence similarity 78, member B

decreases expression

Sodium Glutamate results in decreased expression of FAM78B mRNA

NCBI chr13:79,162,393...79,250,958
Ensembl chr13:79,162,228...79,250,500

G

FANCD2 and FANCI associated nuclease 1

affects methylation

Sodium Glutamate affects the methylation of FAN1 gene

NCBI chr 1:117,915,323...117,945,044
Ensembl chr 1:117,917,099...117,944,977

G

Fas ligand

increases expression
multiple interactions

Sodium Glutamate results in increased expression of FASL mRNA
SB 203580 inhibits the reaction [Sodium Glutamate results in increased expression of FASL mRNA]

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

fatty acid synthase

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of FASN mRNA; fructooligosaccharide inhibits the reaction [Sodium Glutamate results in increased expression of FASN mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of FASN mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of FASN protein]
Sodium Glutamate results in increased expression of FASN mRNA; Sodium Glutamate results in increased expression of FASN protein

PMID:19001666 PMID:19724016 PMID:26092479 PMID:32103741

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

FAT atypical cadherin 3

decreases expression

Sodium Glutamate results in decreased expression of FAT3 mRNA

NCBI chr 8:12,691,470...13,274,336
Ensembl chr 8:12,694,019...13,273,135

G

fibulin 1

decreases expression

Sodium Glutamate results in decreased expression of FBLN1 mRNA

NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075

G

fibrillin 2

increases expression

Sodium Glutamate results in increased expression of FBN2 mRNA

NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976

G

F-box protein 15

affects methylation

Sodium Glutamate affects the methylation of FBXO15 gene

NCBI chr18:78,319,577...78,634,695
Ensembl chr18:78,319,534...78,390,765

G

F-box protein 41

increases expression

Sodium Glutamate results in increased expression of FBXO41 mRNA

NCBI chr 4:118,007,517...118,039,547
Ensembl chr 4:118,010,978...118,039,406

G

farnesyl diphosphate synthase

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of FDPS mRNA

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

fibroblast growth factor 2

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of FGF2 mRNA

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

fibroblast growth factor 21

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of FGF21 mRNA

NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454

G

fibroblast growth factor 8

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of FGF8 mRNA

NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359

G

fibroblast growth factor receptor 2

increases expression

Sodium Glutamate results in increased expression of FGFR2 mRNA

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

G

Fms related receptor tyrosine kinase 1

decreases expression

Sodium Glutamate results in decreased expression of FLT1 protein

NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626

G

flavin containing dimethylaniline monoxygenase 2

increases expression
multiple interactions

Sodium Glutamate results in increased expression of FMO2 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of FMO2 mRNA; [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of FMO2 mRNA

PMID:19001666 PMID:20111022

NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308

G

fibromodulin

increases expression

Sodium Glutamate results in increased expression of FMOD mRNA

NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133

G

folate receptor beta

decreases expression

Sodium Glutamate results in decreased expression of FOLR2 mRNA

NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724

G

Fos proto-oncogene, AP-1 transcription factor subunit

decreases expression

Sodium Glutamate results in decreased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box B2

increases expression

Sodium Glutamate results in increased expression of FOXB2 mRNA

NCBI chr 1:214,232,731...214,234,226
Ensembl chr 1:214,232,731...214,234,226

G

forkhead box O3

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of FOXO3 mRNA

NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561

G

forkhead box P4

decreases expression

Sodium Glutamate results in decreased expression of FOXP4 mRNA

NCBI chr 9:13,058,506...13,115,406
Ensembl chr 9:13,058,476...13,114,879

G

follicle stimulating hormone subunit beta

decreases secretion

Sodium Glutamate results in decreased secretion of FSHB protein

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

formimidoyltransferase cyclodeaminase

increases expression

Sodium Glutamate results in increased expression of FTCD mRNA

NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735

G

FXYD domain-containing ion transport regulator 6

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of FXYD6 mRNA

NCBI chr 8:45,679,054...45,705,958
Ensembl chr 8:45,678,885...45,705,958

G

G0/G1switch 2

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

glucose-6-phosphate dehydrogenase

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of G6PDX mRNA

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

glutamate decarboxylase 1

increases expression
decreases expression

Sodium Glutamate results in increased expression of GAD1 protein
Sodium Glutamate results in decreased expression of GAD1 mRNA

NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333

G

glutamate decarboxylase 2

affects expression
increases expression
decreases expression

Sodium Glutamate affects the expression of GAD2 protein
Sodium Glutamate results in increased expression of GAD2 mRNA
Sodium Glutamate results in decreased expression of GAD2 protein

NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155

G

growth arrest and DNA-damage-inducible, beta

multiple interactions
increases expression

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of GADD45B mRNA; [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of GADD45B mRNA
Sodium Glutamate results in increased expression of GADD45B mRNA

PMID:19001666 PMID:20111022 PMID:23783067

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

G

UDP-galactose-4-epimerase

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of GALE mRNA

NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388

G

galactokinase 1

multiple interactions
increases expression

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of GALK1 mRNA; [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of GALK1 mRNA
Sodium Glutamate results in increased expression of GALK1 mRNA

PMID:19001666 PMID:20111022

NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337

G

polypeptide N-acetylgalactosaminyltransferase 10

decreases expression

Sodium Glutamate results in decreased expression of GALNT10 mRNA

NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013

G

galanin-like peptide

increases expression

Sodium Glutamate results in increased expression of GALP mRNA

NCBI chr 1:67,684,023...67,703,121
Ensembl chr 1:67,684,025...67,702,269

G

growth arrest-specific 2 like 1

decreases expression

Sodium Glutamate results in decreased expression of GAS2L1 mRNA

NCBI chr14:79,955,350...79,961,830
Ensembl chr14:79,950,555...79,961,438

G

1,4-alpha-glucan branching enzyme 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of GBE1 mRNA

NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210

G

glycerophosphodiester phosphodiesterase domain containing 5

decreases expression

Sodium Glutamate results in decreased expression of GDPD5 mRNA

NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446

G

glial fibrillary acidic protein

increases expression

Sodium Glutamate results in increased expression of GFAP mRNA

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

GTP dependent ribosome recycling factor mitochondrial 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of GFM2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of GFM2 mRNA

NCBI chr 2:28,449,452...28,488,200
Ensembl chr 2:28,449,517...28,488,197

G

Gfo/Idh/MocA-like oxidoreductase domain containing 2

increases expression

Sodium Glutamate results in increased expression of GFOD2 mRNA

NCBI chr19:33,599,689...33,647,060
Ensembl chr19:33,604,187...33,647,004

G

growth hormone 1

affects expression
decreases expression
decreases secretion
multiple interactions

Sodium Glutamate affects the expression of GH1 protein
Sodium Glutamate results in decreased expression of GH1 mRNA; Sodium Glutamate results in decreased expression of GH1 protein
Sodium Glutamate results in decreased secretion of GH1 protein
[Octreotide co-treated with Sodium Glutamate] results in decreased expression of and results in decreased secretion of GH1 protein; [Sodium Glutamate co-treated with GH1 protein] results in decreased splicing of CYP2C11 mRNA; [Sodium Glutamate co-treated with GH1 protein] results in increased splicing of CYP2C11 mRNA; [Sodium Glutamate co-treated with GH1 protein] results in increased ubiquitination of CYP2C11 protein; GH1 protein affects the reaction [Sodium Glutamate results in decreased activity of CYP2C11 protein]; GH1 protein affects the reaction [Sodium Glutamate results in decreased expression of CYP2C11 mRNA]; GH1 protein inhibits the reaction [Sodium Glutamate results in decreased activity of CYP2C11 protein]; GH1 protein inhibits the reaction [Sodium Glutamate results in decreased expression of and results in decreased activity of CYP3A2 protein]; GH1 protein inhibits the reaction [Sodium Glutamate results in decreased expression of IGF1 mRNA]; GH1 protein inhibits the reaction [Sodium Glutamate results in increased expression of IGF1R mRNA]; GHRH protein affects the reaction [Sodium Glutamate results in decreased expression of GH1 mRNA]; JI-38 inhibits the reaction [Sodium Glutamate results in decreased secretion of GH1 protein]; Sodium Glutamate inhibits the reaction [GH1 protein results in decreased expression of SOCS2 mRNA]; Sodium Glutamate inhibits the reaction [GH1 protein results in increased expression of CYP2C11 protein]; Sodium Glutamate inhibits the reaction [GH1 protein results in increased expression of GHR mRNA]; Sodium Glutamate inhibits the reaction [GH1 protein results in increased expression of GHR protein]; Sodium Glutamate inhibits the reaction [GH1 protein results in increased expression of SOCS2 mRNA]; Sodium Glutamate inhibits the reaction [GH1 protein results in increased expression of SOCS2 protein]; Sodium Glutamate inhibits the reaction [GHRL protein results in increased secretion of GH1 protein]; Sodium Glutamate results in decreased expression of and results in decreased secretion of GH1 protein

PMID:7476908 PMID:7711889 PMID:8368293 PMID:8496838 PMID:9053782 More...

NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078

G

GH3 domain containing

decreases expression

Sodium Glutamate results in decreased expression of GHDC mRNA

NCBI chr10:85,693,612...85,697,833
Ensembl chr10:85,693,616...85,697,865

G

growth hormone receptor

increases expression
multiple interactions

Sodium Glutamate results in increased expression of GHR mRNA; Sodium Glutamate results in increased expression of GHR protein
Sodium Glutamate inhibits the reaction [GH1 protein results in increased expression of GHR mRNA]; Sodium Glutamate inhibits the reaction [GH1 protein results in increased expression of GHR protein]

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

growth hormone releasing hormone

multiple interactions
decreases expression

[Sodium Glutamate co-treated with Octreotide] results in decreased expression of GHRH mRNA; GHRH protein affects the reaction [Sodium Glutamate results in decreased expression of GH1 mRNA]
Sodium Glutamate results in decreased expression of GHRH mRNA

PMID:2004597 PMID:8368293 PMID:9053782

NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889

G

growth hormone releasing hormone receptor

increases expression

Sodium Glutamate results in increased expression of GHRHR mRNA

NCBI chr 4:84,498,159...84,532,851
Ensembl chr 4:84,500,212...84,532,776

G

ghrelin and obestatin prepropeptide

multiple interactions

Sodium Glutamate inhibits the reaction [GHRL protein results in increased secretion of GH1 protein]

NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621

G

growth hormone secretagogue receptor

increases expression

Sodium Glutamate results in increased expression of GHSR mRNA

NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865

G

GRB10 interacting GYF protein 1

multiple interactions
increases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of GIGYF1 mRNA
Sodium Glutamate results in increased expression of GIGYF1 mRNA

NCBI chr12:19,166,070...19,181,570
Ensembl chr12:19,166,088...19,175,023

G

gastric inhibitory polypeptide

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate] results in increased expression of GIP protein; Sodium Glutamate inhibits the reaction [Aspartame promotes the reaction [Fats, Unsaturated results in increased expression of GIP protein]]

NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503

G

glycerol kinase

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of GK mRNA
Sodium Glutamate results in increased expression of GK mRNA

NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631

G

glutaredoxin

decreases expression
multiple interactions
increases expression

Sodium Glutamate results in decreased expression of GLRX mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of GLRX mRNA
Sodium Glutamate results in increased expression of GLRX mRNA

PMID:20111022 PMID:22078008

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glutamate dehydrogenase 1

multiple interactions

Sodium Glutamate results in decreased expression of and results in decreased activity of GLUD1 protein

NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957

G

glucocorticoid modulatory element binding protein 2

increases expression

Sodium Glutamate results in increased expression of GMEB2 mRNA

NCBI chr 3:168,362,650...168,400,788
Ensembl chr 3:168,362,650...168,400,788

G

glia maturation factor, beta

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of GMFB mRNA

NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331

G

glyceronephosphate O-acyltransferase

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of GNPAT mRNA

NCBI chr19:52,822,326...52,848,872
Ensembl chr19:52,822,319...52,852,361

G

glutamic-oxaloacetic transaminase 1

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of GOT1 mRNA

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glycerol-3-phosphate acyltransferase 3

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of GPAT3 mRNA

NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490

G

glypican 2

increases expression

Sodium Glutamate results in increased expression of GPC2 mRNA

NCBI chr12:17,277,875...17,284,297
Ensembl chr12:17,277,875...17,284,208

G

G protein-coupled receptor 85

increases expression

Sodium Glutamate results in increased expression of GPR85 mRNA

NCBI chr 4:42,100,138...42,109,584
Ensembl chr 4:42,102,941...42,109,566

G

G protein-coupled receptor, class C, group 5, member C

increases expression

Sodium Glutamate results in increased expression of GPRC5C mRNA

NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926

G

glutamic--pyruvic transaminase

increases expression
decreases expression
increases activity
multiple interactions

Sodium Glutamate results in increased expression of GPT protein
Sodium Glutamate results in decreased expression of GPT protein
Sodium Glutamate results in increased activity of GPT protein
2-ethoxy-3-(4-(2-(4-trifluoromethanesulfonyloxyphenyl)ethoxy)phenyl)propionic acid promotes the reaction [Sodium Glutamate results in increased activity of GPT protein]; 3-(4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-ylcarbonyl)thiazolidine affects the reaction [[Dietary Fats co-treated with Sodium Glutamate] affects the expression of GPT protein]; [Dietary Fats co-treated with Sodium Glutamate] affects the expression of GPT protein; Bezafibrate promotes the reaction [Sodium Glutamate results in increased expression of GPT protein]; fructooligosaccharide inhibits the reaction [Sodium Glutamate results in increased expression of GPT protein]; Rosiglitazone promotes the reaction [Sodium Glutamate results in increased activity of GPT protein]

PMID:18048028 PMID:19724016 PMID:21205225 PMID:21549692 PMID:26670228 More...

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

decreases expression
increases expression
multiple interactions

Sodium Glutamate results in decreased expression of GPX1 mRNA
Sodium Glutamate results in increased expression of GPX1 mRNA; Sodium Glutamate results in increased expression of GPX1 protein
SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of GPX1 mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of GPX1 protein]

PMID:19724016 PMID:30733785

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

decreases expression
affects expression

Sodium Glutamate results in decreased expression of GPX2 protein
Sodium Glutamate affects the expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutamate ionotropic receptor AMPA type subunit 2

affects expression
multiple interactions

Sodium Glutamate affects the expression of GRIA2 protein
SB 203580 affects the reaction [Sodium Glutamate affects the expression of GRIA2]

PMID:15139026 PMID:16782274

NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510

G

galectin-related inter-fiber protein

increases expression

Sodium Glutamate results in increased expression of GRIFIN mRNA

NCBI chr12:14,080,170...14,082,892
Ensembl chr12:14,080,910...14,082,877

G

glutamate ionotropic receptor kainate type subunit 3

increases expression

Sodium Glutamate results in increased expression of GRIK3 mRNA

NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307

G

glutamate ionotropic receptor kainate type subunit 5

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of GRIK5 mRNA

NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125

G

glutamate ionotropic receptor NMDA type subunit 1

increases expression

Sodium Glutamate results in increased expression of GRIN1

NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603

G

glutamate ionotropic receptor NMDA type subunit 2C

increases expression

Sodium Glutamate results in increased expression of GRIN2C mRNA

NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427

G

glutamate ionotropic receptor NMDA type subunit 2D

decreases expression
increases expression

Sodium Glutamate results in decreased expression of GRIN2D mRNA
Sodium Glutamate results in increased expression of GRIN2D mRNA

PMID:11872244 PMID:20928830

NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793

G

glutathione-disulfide reductase

decreases activity
multiple interactions

Sodium Glutamate results in decreased activity of GSR protein
Sodium Glutamate results in increased expression of and results in decreased activity of GSR protein; Tea inhibits the reaction [Sodium Glutamate results in decreased activity of GSR protein]

PMID:25473020 PMID:29679905 PMID:30733785

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase mu 2

increases expression

Sodium Glutamate results in increased expression of GSTM2 mRNA

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase mu 4

multiple interactions
increases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of GSTM4 mRNA
Sodium Glutamate results in increased expression of GSTM4 mRNA

NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323

G

glutathione S-transferase, mu 5

increases expression

Sodium Glutamate results in increased expression of GSTM3 mRNA

PMID:19001666 PMID:25473020

NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553

G

glutathione S-transferase pi 1

decreases expression

Sodium Glutamate results in decreased expression of GSTP1 protein

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

general transcription factor IIB

multiple interactions
increases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of GTF2B mRNA
Sodium Glutamate results in increased expression of GTF2B mRNA

NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651

G

guanylate cyclase activator 1A

decreases expression

Sodium Glutamate results in decreased expression of GUCA1A mRNA

NCBI chr 9:13,588,988...13,598,566
Ensembl chr 9:13,588,525...13,598,565

G

H1.4 linker histone, cluster member

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of H1F4 mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in decreased expression of H1F4 mRNA

NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403

G

3-hydroxyacyl-CoA dehydratase 2

decreases expression

Sodium Glutamate results in decreased expression of HACD2 mRNA

NCBI chr11:65,667,671...65,762,903
Ensembl chr11:65,670,281...65,762,889

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HADHA mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of HADHA mRNA

NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HADHB mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of HADHB mRNA

NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869

G

hydroxyacid oxidase 2

decreases expression

Sodium Glutamate results in decreased expression of HAO2 mRNA

NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425

G

hyperpolarization-activated cyclic nucleotide-gated potassium channel 1

multiple interactions
decreases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of HCN1 mRNA
Sodium Glutamate results in decreased expression of HCN1 mRNA

NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774

G

histone deacetylase 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HDAC1 mRNA

NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111

G

histone deacetylase 5

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HDAC5 mRNA

NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235

G

HD domain containing 2

decreases expression

Sodium Glutamate results in decreased expression of HDDC2 mRNA

NCBI chr 1:26,294,030...26,313,914
Ensembl chr 1:26,294,030...26,313,935

G

HEAT repeat containing 6

decreases expression

Sodium Glutamate results in decreased expression of HEATR6 mRNA

NCBI chr10:68,635,048...68,665,445
Ensembl chr10:68,635,065...68,664,105

G

HEAT repeat containing 9

increases expression

Sodium Glutamate results in increased expression of HEATR9 mRNA

NCBI chr10:68,309,128...68,320,650
Ensembl chr10:68,308,579...68,319,376

G

heme binding protein 1

increases expression

Sodium Glutamate results in increased expression of HEBP1 mRNA

NCBI chr 4:167,974,316...168,003,854
Ensembl chr 4:167,974,319...168,003,854

G

hes family bHLH transcription factor 2

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of HES2 mRNA

NCBI chr 5:162,667,190...162,668,235
Ensembl chr 5:162,667,190...162,668,235

G

hes-related family bHLH transcription factor with YRPW motif-like

decreases expression

Sodium Glutamate results in decreased expression of HEYL mRNA

NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152

G

hepatocyte growth factor

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HGF mRNA

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

heme oxygenase 1

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of HMOX1 mRNA; Sodium Glutamate results in decreased expression of HMOX1 protein
Tea inhibits the reaction [Sodium Glutamate results in decreased expression of HMOX1 mRNA]; Tea inhibits the reaction [Sodium Glutamate results in decreased expression of HMOX1 protein]

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

homeo box C10

increases expression

Sodium Glutamate results in increased expression of HOXC10 mRNA

NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:134,103,643...134,108,966

G

HRas proto-oncogene, GTPase

decreases expression

Sodium Glutamate results in decreased expression of HRAS mRNA

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

hydroxysteroid 11-beta dehydrogenase 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of HSD11B1 mRNA

NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of HSD3B2 mRNA

NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

decreases expression

Sodium Glutamate results in decreased expression of HSD3B7 mRNA

NCBI chr 1:182,412,216...182,415,447
Ensembl chr 1:182,412,151...182,415,442

G

heat shock transcription factor 4

decreases expression

Sodium Glutamate results in decreased expression of HSF4 mRNA

NCBI chr19:33,147,755...33,153,479
Ensembl chr19:33,147,755...33,153,479

G

heat shock protein family A (Hsp70) member 5

increases expression

Sodium Glutamate results in increased expression of HSPA5 mRNA

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family B (small) member 1

decreases expression

Sodium Glutamate results in decreased expression of HSPB1 mRNA

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

G

heparan sulfate proteoglycan 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HSPG2 mRNA

NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594

G

5-hydroxytryptamine receptor 6

increases expression

Sodium Glutamate results in increased expression of HTR6 mRNA

NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912

G

isocitrate dehydrogenase (NADP(+)) 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of IDH2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of IDH2 mRNA; [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of IDH2 mRNA

PMID:20111022 PMID:23783067

NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025

G

isopentenyl-diphosphate delta isomerase 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of IDI1 mRNA

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

intermediate filament family orphan 2

increases expression

Sodium Glutamate results in increased expression of IFFO2 mRNA

NCBI chr 5:151,830,900...151,876,948
Ensembl chr 5:151,830,701...151,925,345

G

interferon gamma

multiple interactions
decreases expression

Plant Extracts inhibits the reaction [Sodium Glutamate results in decreased expression of IFNG protein]

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

insulin-like growth factor 1

multiple interactions
decreases secretion
decreases expression

[Sodium Glutamate co-treated with Azoxymethane] affects the expression of IGF1 mRNA
GH1 protein inhibits the reaction [Sodium Glutamate results in decreased expression of IGF1 mRNA]; JI-38 inhibits the reaction [Sodium Glutamate results in decreased secretion of IGF1 protein]
Sodium Glutamate results in decreased expression of IGF1 mRNA; Sodium Glutamate results in decreased expression of IGF1 protein

PMID:7533119 PMID:7711889 PMID:8368293 PMID:10718930 PMID:22223845

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 1 receptor

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of IGF1R mRNA; Sodium Glutamate affects the reaction [Azoxymethane affects the expression of IGF1R mRNA]
GH1 protein inhibits the reaction [Sodium Glutamate results in increased expression of IGF1R mRNA]

PMID:7711889 PMID:19001666 PMID:22223845

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor 2

multiple interactions

[Sodium Glutamate co-treated with Azoxymethane] affects the expression of IGF2 mRNA

NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018

G

insulin-like growth factor binding protein 3

decreases expression

Sodium Glutamate results in decreased expression of IGFBP3 mRNA

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

inhibitor of nuclear factor kappa B kinase subunit beta

increases phosphorylation
multiple interactions

Sodium Glutamate results in increased phosphorylation of IKBKB protein
Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of IKBKB protein]

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

G

interleukin 10

increases expression

Sodium Glutamate results in increased expression of IL10 protein

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 18 receptor accessory protein

increases expression

Sodium Glutamate results in increased expression of IL18RAP mRNA

NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959

G

interleukin 1 beta

increases response to substance

Sodium Glutamate results in increased susceptibility to IL1B protein

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor-like 2

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of IL1RL2 mRNA

NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667

G

interleukin 2

increases expression

Sodium Glutamate results in increased expression of IL2 mRNA

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 21

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of IL21 mRNA

NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996

G

interleukin 6

increases expression
affects expression
multiple interactions

Sodium Glutamate results in increased expression of IL6 mRNA; Sodium Glutamate results in increased expression of IL6 protein
Sodium Glutamate affects the expression of IL6 mRNA; Sodium Glutamate affects the expression of IL6 protein
[Sodium Glutamate co-treated with Pioglitazone] results in decreased expression of IL6 protein; [Sodium Glutamate co-treated with Plant Extracts] results in decreased expression of IL6 protein; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of IL6 mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of IL6 protein]; Glycine affects the reaction [Sodium Glutamate affects the expression of IL6 mRNA]; Glycine affects the reaction [Sodium Glutamate affects the expression of IL6 protein]; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased expression of IL6 mRNA]; Plant Extracts inhibits the reaction [Sodium Glutamate results in increased expression of IL6 mRNA]

PMID:18930730 PMID:19800637 PMID:21205225 PMID:25834641 PMID:27918843 More...

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

inner membrane mitochondrial protein

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of IMMT mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of IMMT mRNA

NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109

G

inhibitor of growth family, member 4

increases expression
multiple interactions

Sodium Glutamate results in increased expression of ING4 mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of ING4 mRNA

NCBI chr 4:157,841,882...157,850,519
Ensembl chr 4:157,841,951...157,850,265

G

INO80 complex subunit E

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of INO80E mRNA

NCBI chr 1:181,461,406...181,472,059
Ensembl chr 1:181,461,408...181,472,469

G

inositol polyphosphate-5-phosphatase J

decreases expression

Sodium Glutamate results in decreased expression of INPP5J mRNA

NCBI chr14:78,374,161...78,385,305
Ensembl chr14:78,374,161...78,385,326

G

insulin 1

multiple interactions
increases expression
increases secretion
decreases expression

3,3',4',5,7-pentamethylquercetin inhibits the reaction [Sodium Glutamate results in increased expression of INS1 protein]; [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of INS1 protein; [Sodium Glutamate co-treated with Tea] affects the expression of INS1 protein; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of INS1 protein]; Azoxymethane inhibits the reaction [Sodium Glutamate results in increased expression of INS1 protein]; fructooligosaccharide inhibits the reaction [Sodium Glutamate results in increased expression of INS1 protein]; Rosiglitazone inhibits the reaction [Sodium Glutamate results in increased expression of INS1 protein]
Sodium Glutamate results in increased secretion of INS1 protein
Sodium Glutamate results in decreased expression of INS1 protein
Carbenoxolone inhibits the reaction [Sodium Glutamate results in increased secretion of INS1 protein]

PMID:11319642 PMID:18930730 PMID:19001666 PMID:19800637 PMID:20111022 More...

NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536

G

insulin 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] results in increased expression of INS2 protein; [Fats, Unsaturated co-treated with Sodium Glutamate] results in increased expression of INS2 protein

NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775

G

IQ motif containing H

decreases expression

Sodium Glutamate results in decreased expression of IQCH mRNA

NCBI chr 8:63,889,816...64,083,248
Ensembl chr 8:63,892,370...64,083,223

G

iron responsive element binding protein 2

decreases expression

Sodium Glutamate results in decreased expression of IREB2 mRNA

NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611

G

interferon regulatory factor 2 binding protein 2

decreases expression

Sodium Glutamate results in decreased expression of IRF2BP2 mRNA

NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642

G

insulin receptor substrate 2

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of IRS2 mRNA
2-ethoxy-3-(4-(2-(4-trifluoromethanesulfonyloxyphenyl)ethoxy)phenyl)propionic acid inhibits the reaction [Sodium Glutamate results in decreased expression of IRS2 mRNA]

NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482

G

integrin alpha FG-GAP repeat containing 2

decreases expression

Sodium Glutamate results in decreased expression of ITFG2 mRNA

NCBI chr 4:161,684,249...161,698,315
Ensembl chr 4:161,684,249...161,698,422

G

integrin subunit alpha 2b

increases expression
multiple interactions

Sodium Glutamate results in increased expression of ITGA2B mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in decreased expression of ITGA2B mRNA

NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168

G

integrin subunit alpha 7

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of ITGA7 mRNA

NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450

G

integrin subunit alpha V

decreases expression

Sodium Glutamate results in decreased expression of ITGAV mRNA

NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639

G

integrin subunit beta 3

increases expression

Sodium Glutamate results in increased expression of ITGB3 mRNA

NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679

G

integral membrane protein 2A

multiple interactions
decreases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of ITM2A mRNA
Sodium Glutamate results in decreased expression of ITM2A mRNA

NCBI chr X:72,486,383...72,492,344
Ensembl chr X:72,486,381...72,492,363

G

inositol 1,4,5-trisphosphate receptor, type 3

increases expression
multiple interactions

Sodium Glutamate results in increased expression of ITPR3 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of ITPR3 mRNA

PMID:19001666 PMID:20111022

NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337

G

potassium voltage-gated channel subfamily H member 1

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of KCNH1 mRNA

NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740

G

potassium inwardly-rectifying channel, subfamily J, member 12

decreases expression

Sodium Glutamate results in decreased expression of KCNJ12 mRNA

NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492

G

potassium inwardly-rectifying channel, subfamily J, member 16

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of KCNJ16 mRNA
Sodium Glutamate results in increased expression of KCNJ16 mRNA

NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702

G

potassium two pore domain channel subfamily K member 1

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of KCNK1 mRNA
Sodium Glutamate results in increased expression of KCNK1 mRNA

NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724

G

potassium calcium-activated channel subfamily N member 2

decreases expression

Sodium Glutamate results in decreased expression of KCNN2 mRNA

NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347

G

KDEL endoplasmic reticulum protein retention receptor 3

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of KDELR3 mRNA

NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600

G

kinase insert domain receptor

increases expression
multiple interactions

Sodium Glutamate results in increased expression of KDR protein
[Semaxinib co-treated with Sodium Glutamate] results in increased expression of KDR protein

PMID:28755050 PMID:36732937

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

G

kirre like nephrin family adhesion molecule 3

increases expression

Sodium Glutamate results in increased expression of KIRREL3 mRNA

NCBI chr 8:32,865,779...33,407,555
Ensembl chr 8:32,862,776...33,405,676

G

kelch-like family member 3

decreases expression

Sodium Glutamate results in decreased expression of KLHL3 mRNA

NCBI chr17:6,523,089...6,645,971
Ensembl chr17:6,521,912...6,642,154

G

KRAS proto-oncogene, GTPase

decreases expression

Sodium Glutamate results in decreased expression of KRAS mRNA

NCBI chr 4:178,185,418...178,218,484

G

keratin 19

increases expression

Sodium Glutamate results in increased expression of KRT19 mRNA

NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799

G

lactate dehydrogenase D

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of LDHD mRNA
Sodium Glutamate results in increased expression of LDHD mRNA

NCBI chr19:39,583,529...39,588,397
Ensembl chr19:39,573,621...39,595,575

G

low density lipoprotein receptor

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of LDLR mRNA

NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580

G

leptin

multiple interactions
affects expression
increases expression

[Sodium Glutamate co-treated with Aspartame] promotes the reaction [Fats, Unsaturated results in increased expression of LEP protein]; [Sodium Glutamate co-treated with Aurothioglucose] results in increased expression of LEP mRNA; [Sodium Glutamate co-treated with Aurothioglucose] results in increased expression of LEP protein; [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of LEP protein; [Sodium Glutamate co-treated with Tea] affects the expression of LEP protein; [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of LEP mRNA; [Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of LEP protein; Bezafibrate inhibits the reaction [Sodium Glutamate results in increased expression of LEP protein]; Glycine affects the reaction [Sodium Glutamate affects the expression of LEP protein]; Sodium Glutamate promotes the reaction [Fats, Unsaturated results in increased expression of LEP protein]
Sodium Glutamate results in increased expression of LEP mRNA; Sodium Glutamate results in increased expression of LEP protein

PMID:7489415 PMID:7657836 PMID:9794456 PMID:14657608 PMID:15809509 More...

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

G

galectin 4

increases expression

Sodium Glutamate results in increased expression of LGALS4 mRNA

NCBI chr 1:84,124,766...84,132,481
Ensembl chr 1:84,124,764...84,132,481

G

luteinizing hormone subunit beta

decreases secretion

Sodium Glutamate results in decreased secretion of LHB protein

NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

LIM domain kinase 1

decreases expression

Sodium Glutamate results in decreased expression of LIMK1 mRNA

NCBI chr12:22,026,697...22,060,605
Ensembl chr12:22,026,672...22,060,606

G

lin-54 DREAM MuvB core complex component

decreases expression

Sodium Glutamate results in decreased expression of LIN54 mRNA

NCBI chr14:9,129,775...9,188,244
Ensembl chr14:9,130,336...9,187,790

G

lipase E, hormone sensitive type

decreases activity
decreases expression

Sodium Glutamate results in decreased activity of LIPE protein
Sodium Glutamate results in decreased expression of LIPE mRNA

NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310

G

lipase G, endothelial type

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of LIPG mRNA

NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260

G

lysyl oxidase-like 1

decreases expression

Sodium Glutamate results in decreased expression of LOXL1 mRNA

NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356

G

lipin 1

decreases expression

Sodium Glutamate results in decreased expression of LPIN1 mRNA

NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097

G

LDL receptor related protein 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of LRP1 mRNA

NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910

G

LDL receptor related protein 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of LRP2 mRNA

NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708

G

LDL receptor related protein 4

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of LRP4 mRNA

NCBI chr 3:77,429,600...77,483,593
Ensembl chr 3:77,429,798...77,483,593

G

LDL receptor related protein associated protein 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of LRPAP1 mRNA

NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414

G

leucine rich repeat containing 26

increases expression

Sodium Glutamate results in increased expression of LRRC26 mRNA

NCBI chr 3:8,102,361...8,103,687
Ensembl chr 3:8,102,361...8,103,687

G

leucine rich repeat containing 46

increases expression

Sodium Glutamate results in increased expression of LRRC46 mRNA

NCBI chr10:82,021,314...82,033,575
Ensembl chr10:82,021,330...82,033,724

G

leucine rich repeat containing 73

decreases expression

Sodium Glutamate results in decreased expression of LRRC73 mRNA

NCBI chr 9:14,726,157...14,730,144
Ensembl chr 9:14,726,158...14,729,158

G

LUC7-like

increases expression

Sodium Glutamate results in increased expression of LUC7L mRNA

NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112

G

lymphocyte antigen 6 family member M

increases expression

Sodium Glutamate results in increased expression of LY6M mRNA

NCBI chr 7:106,863,167...106,867,047
Ensembl chr 7:106,865,291...106,867,047

G

magnesium transporter 1

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of MAGT1 mRNA

NCBI chr X:71,038,489...71,079,704
Ensembl chr X:71,038,489...71,079,699

G

monoamine oxidase A

multiple interactions
increases expression

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of MAOA mRNA
Sodium Glutamate results in increased expression of MAOA mRNA

NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593

G

mitogen activated protein kinase kinase 1

decreases expression

Sodium Glutamate results in decreased expression of MAP2K1 mRNA

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase kinase 2

decreases expression

Sodium Glutamate results in decreased expression of MAP2K2 mRNA

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

G

mitogen activated protein kinase kinase 3

decreases expression

Sodium Glutamate results in decreased expression of MAP2K3 mRNA

NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492

G

mitogen activated protein kinase kinase 4

decreases expression

Sodium Glutamate results in decreased expression of MAP2K4 mRNA

NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993

G

mitogen-activated protein kinase kinase kinase 1

decreases expression

Sodium Glutamate results in decreased expression of MAP3K1 mRNA

NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463

G

mitogen-activated protein kinase kinase kinase 15

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in decreased expression of MAP3K15 mRNA

NCBI chr X:34,713,150...34,859,054
Ensembl chr X:34,713,175...34,858,807

G

mitogen activated protein kinase kinase kinase 3

decreases expression

Sodium Glutamate results in decreased expression of MAP3K3 mRNA

NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848

G

mitogen activated protein kinase kinase kinase kinase 1

decreases expression

Sodium Glutamate results in decreased expression of MAP4K1 mRNA

NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493

G

mitogen-activated protein kinase 12

decreases expression

Sodium Glutamate results in decreased expression of MAPK12 mRNA

NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664

G

mitogen activated protein kinase 13

affects expression

Sodium Glutamate affects the expression of MAPK13 mRNA

NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222

G

mitogen-activated protein kinase 8

decreases expression

Sodium Glutamate results in decreased expression of MAPK8 mRNA

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

mitogen-activated protein kinase 8 interacting protein 1

decreases expression

Sodium Glutamate results in decreased expression of MAPK8IP1 mRNA

NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884

G

methyl-CpG binding domain 4 DNA glycosylase

increases expression

Sodium Glutamate results in increased expression of MBD4 mRNA

NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982

G

melanocortin 4 receptor

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of MC4R mRNA

NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719

G

multiple coagulation factor deficiency 2, ER cargo receptor complex subunit

decreases expression

Sodium Glutamate results in decreased expression of MCFD2 mRNA

NCBI chr 6:7,274,469...7,285,841
Ensembl chr 6:7,274,469...7,285,841

G

mitochondrial calcium uniporter

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MCU mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of MCU mRNA

NCBI chr20:27,417,529...27,580,110
Ensembl chr20:27,417,526...27,580,110

G

malate dehydrogenase 1

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of MDH1 mRNA

NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925

G

midkine

decreases expression

Sodium Glutamate results in decreased expression of MDK mRNA

NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130

G

MDM2 proto-oncogene

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MDM2 mRNA

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

mediator complex subunit 12L

decreases expression

Sodium Glutamate results in decreased expression of MED12L mRNA

NCBI chr 2:143,253,048...143,576,507
Ensembl chr 2:143,252,139...143,573,741

G

mediator complex subunit 23

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MED23 mRNA

NCBI chr 1:20,490,315...20,558,461
Ensembl chr 1:20,490,315...20,537,463

G

mediator complex subunit 31

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of MED31 mRNA

NCBI chr10:56,836,944...56,840,326
Ensembl chr10:56,836,944...56,840,326

G

myocyte enhancer factor 2D

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MEF2D mRNA

NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457

G

multiple EGF-like domains 10

increases expression

Sodium Glutamate results in increased expression of MEGF10 mRNA

NCBI chr18:50,605,231...50,755,441
Ensembl chr18:50,605,656...50,754,456

G

monoglyceride lipase

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of MGLL mRNA

NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179

G

microtubule associated monooxygenase, calponin and LIM domain containing 3

increases expression

Sodium Glutamate results in increased expression of MICAL3 mRNA

NCBI chr 4:154,152,776...154,353,274
Ensembl chr 4:154,153,834...154,302,590

G

mitochondrial contact site and cristae organizing system subunit 10

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MINOS1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of MINOS1 mRNA

NCBI chr 5:151,341,124...151,367,403
Ensembl chr 5:151,339,176...151,367,485

G

mitochondrial contact site and cristae organizing system subunit 13

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of MICOS13 mRNA

NCBI chr 9:1,439,841...1,441,782
Ensembl chr 9:1,439,058...1,442,076

G

mitochondrial calcium uptake 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MICU1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of MICU1 mRNA

NCBI chr20:27,668,681...27,816,322
Ensembl chr20:27,668,747...27,814,964

G

microRNA 142

decreases expression

Sodium Glutamate results in decreased expression of MIR142 mRNA

NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967

G

microRNA 223

decreases expression

Sodium Glutamate results in decreased expression of MIR223 mRNA

NCBI chr X:61,141,887...61,141,996
Ensembl chr X:61,141,887...61,141,996

G

MLX interacting protein-like

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of MLXIPL mRNA
Taurine inhibits the reaction [Sodium Glutamate results in decreased expression of MLXIPL mRNA]

NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112

G

monocyte to macrophage differentiation-associated

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of MMD mRNA

NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528

G

matrix metallopeptidase 28

increases expression

Sodium Glutamate results in increased expression of MMP28 mRNA

NCBI chr10:68,241,138...68,264,866
Ensembl chr10:68,241,138...68,264,866

G

M-phase specific PLK1 interacting protein

increases expression

Sodium Glutamate results in increased expression of MPLKIP mRNA

NCBI chr17:47,373,624...47,376,199
Ensembl chr17:47,373,845...47,376,204

G

mitochondrial ribosomal protein L20

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPL20 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of MRPL20 mRNA

NCBI chr 5:166,408,962...166,413,492
Ensembl chr 5:166,408,962...166,413,492

G

mitochondrial ribosomal protein L3

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPL3 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of MRPL3 mRNA

NCBI chr 8:105,670,184...105,693,544
Ensembl chr 8:105,670,184...105,693,544

G

mitochondrial ribosomal protein L35

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of MRPL35 mRNA

NCBI chr 4:103,865,812...103,876,687
Ensembl chr 4:103,865,812...103,880,887

G

mitochondrial ribosomal protein S12

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPS12 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of MRPS12 mRNA

NCBI chr 1:84,025,896...84,028,896
Ensembl chr 1:84,025,899...84,028,780

G

mitochondrial ribosomal protein S14

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of MRPS14 mRNA

NCBI chr13:72,429,168...72,434,915
Ensembl chr13:72,408,558...72,434,915

G

mitochondrial ribosomal protein S24

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPS24 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of MRPS24 mRNA

NCBI chr14:80,584,671...80,588,801
Ensembl chr14:80,584,673...80,588,871

G

mitochondrial ribosomal protein S27

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPS27 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of MRPS27 mRNA

NCBI chr 2:30,740,007...30,808,577
Ensembl chr 2:30,740,033...30,808,577

G

mitochondrial ribosomal protein S7

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPS7 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of MRPS7 mRNA

NCBI chr10:100,843,691...100,846,838
Ensembl chr10:100,843,356...100,847,129

G

membrane spanning 4-domains A2

increases expression

Sodium Glutamate results in increased expression of MS4A2 mRNA

NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6

decreases expression

Sodium Glutamate results in decreased expression of ND6 mRNA

NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061

G

mitochondrial fission process 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MTFP1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of MTFP1 mRNA

NCBI chr14:78,968,434...78,972,274
Ensembl chr14:78,968,442...78,972,274

G

myotubularin related protein 12

decreases expression

Sodium Glutamate results in decreased expression of MTMR12 mRNA

NCBI chr 2:61,223,714...61,293,270
Ensembl chr 2:61,223,851...61,293,197

G

microsomal triglyceride transfer protein

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of MTTP mRNA
Taurine inhibits the reaction [Sodium Glutamate results in decreased expression of MTTP mRNA]

NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239

G

mevalonate kinase

increases expression

Sodium Glutamate results in increased expression of MVK mRNA

NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882

G

Mycbp associated protein

increases expression

Sodium Glutamate results in increased expression of MYCBPAP mRNA

NCBI chr10:79,450,319...79,470,977
Ensembl chr10:79,450,324...79,470,828

G

myosin VIIA

multiple interactions
increases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of MYO7A mRNA
Sodium Glutamate results in increased expression of MYO7A mRNA

NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157

G

non-SMC condensin I complex, subunit H

increases expression

Sodium Glutamate results in increased expression of NCAPH mRNA

NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180

G

nuclear receptor co-repressor 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NCOR1 mRNA

NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032

G

NADH:ubiquinone oxidoreductase subunit A10

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of NDUFA10 mRNA

NCBI chr 9:93,007,034...93,041,825
Ensembl chr 9:93,007,042...93,042,560

G

NADH:ubiquinone oxidoreductase subunit A12

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFA12 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of NDUFA12 mRNA

NCBI chr 7:28,771,330...28,798,316
Ensembl chr 7:28,771,330...28,798,315

G

NADH:ubiquinone oxidoreductase subunit A13

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of NDUFA13 mRNA

NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726

G

NADH:ubiquinone oxidoreductase subunit A5

multiple interactions
decreases expression

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFA5 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of NDUFA5 mRNA; [Sodium Glutamate co-treated with High Fructose Corn Syrup] affects the expression of NDUFA5 mRNA
Sodium Glutamate results in decreased expression of NDUFA5 mRNA

PMID:20111022 PMID:23783067

NCBI chr 4:52,997,327...53,005,685
Ensembl chr 4:52,995,546...53,005,598

G

NADH:ubiquinone oxidoreductase subunit B10

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFB10 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of NDUFB10 mRNA

NCBI chr10:13,749,273...13,751,434
Ensembl chr10:13,749,275...13,751,442

G

NADH:ubiquinone oxidoreductase subunit B2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFB2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of NDUFB2 mRNA

NCBI chr 4:68,367,526...68,374,609
Ensembl chr15:46,536,062...46,536,851
Ensembl chr 4:46,536,062...46,536,851

G

NADH:ubiquinone oxidoreductase subunit B4

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of NDUFB4 mRNA

NCBI chr11:63,063,723...63,070,426
Ensembl chr11:63,063,795...63,070,425

G

NADH:ubiquinone oxidoreductase subunit B6

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFB6 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of NDUFB6 mRNA

NCBI chr 5:55,400,543...55,410,110
Ensembl chr 5:55,400,543...55,410,181

G

NADH:ubiquinone oxidoreductase subunit B8

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of NDUFB8 mRNA

NCBI chr 1:243,408,656...243,413,715
Ensembl chr 1:243,408,619...243,413,817

G

NADH:ubiquinone oxidoreductase subunit C1

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of NDUFC1 mRNA

NCBI chr 2:135,447,067...135,450,950
Ensembl chr 2:135,447,119...135,450,874

G

NADH:ubiquinone oxidoreductase core subunit S1

multiple interactions
decreases expression

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFS1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of NDUFS1 mRNA
Sodium Glutamate results in decreased expression of NDUFS1 mRNA

PMID:20111022 PMID:23783067

NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893

G

NADH:ubiquinone oxidoreductase subunit S4

multiple interactions
increases expression
decreases expression

[Sodium Glutamate co-treated with High Fructose Corn Syrup] affects the expression of NDUFS4 mRNA
Sodium Glutamate results in increased expression of NDUFS4 mRNA
Sodium Glutamate results in decreased expression of NDUFS4 mRNA

NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846

G

NADH:ubiquinone oxidoreductase subunit S6

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFS6 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of NDUFS6 mRNA

NCBI chr 1:29,968,833...29,977,423
Ensembl chr 1:29,968,842...29,977,467

G

NADH:ubiquinone oxidoreductase core subunit S7

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of NDUFS7 mRNA

NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195

G

NADH:ubiquinone oxidoreductase core subunit V1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFV1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of NDUFV1 mRNA

NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466

G

nebulin

increases expression

Sodium Glutamate results in increased expression of NEB mRNA

NCBI chr 3:36,613,677...36,811,618
Ensembl chr 3:36,613,716...36,811,574

G

NIMA-related kinase 11

increases expression

Sodium Glutamate results in increased expression of NEK11 mRNA

NCBI chr 8:105,767,230...106,026,676
Ensembl chr 8:105,770,548...106,026,676

G

neuraminidase 3

increases expression

Sodium Glutamate results in increased expression of NEU3 mRNA

NCBI chr 1:154,137,732...154,148,879
Ensembl chr 1:154,050,855...154,148,813

G

neurofibromin 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NF1 mRNA

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

G

NFE2 like bZIP transcription factor 2

decreases expression
multiple interactions
increases expression

Sodium Glutamate results in decreased expression of NFE2L2 mRNA; Sodium Glutamate results in decreased expression of NFE2L2 protein
Tea inhibits the reaction [Sodium Glutamate results in decreased expression of NFE2L2 mRNA]; Tea inhibits the reaction [Sodium Glutamate results in decreased expression of NFE2L2 protein]
Sodium Glutamate results in increased expression of NFE2L2 mRNA

PMID:25473020 PMID:29679905

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor, interleukin 3 regulated

increases expression

Sodium Glutamate results in increased expression of NFIL3 mRNA

NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858

G

nuclear factor kappa B subunit 1

multiple interactions
increases expression

Resveratrol inhibits the reaction [Sodium Glutamate results in increased expression of NFKB1 mRNA]

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

NFKB inhibitor beta

multiple interactions

[Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NFKBIB mRNA

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

G

nuclear transcription factor Y subunit alpha

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of NFYA mRNA

NCBI chr 9:12,587,437...12,613,911
Ensembl chr 9:12,586,259...12,613,898

G

nerve growth factor receptor

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of TNFRSF10B mRNA

NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518

G

NHERF family PDZ scaffold protein 4

decreases expression

Sodium Glutamate results in decreased expression of NHERF4 mRNA

NCBI chr 8:44,584,390...44,588,838
Ensembl chr 8:44,584,390...44,588,860

G

NIPA-like domain containing 1

increases expression

Sodium Glutamate results in increased expression of NIPAL1 mRNA

NCBI chr14:35,537,641...35,561,656
Ensembl chr14:35,540,324...35,561,659

G

nucleolar protein 3

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of NOL3 mRNA

NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250

G

nitric oxide synthase 2

multiple interactions
increases expression

[Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 protein
Sodium Glutamate results in increased expression of NOS2 protein

PMID:21999347 PMID:36732937

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

notch receptor 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NOTCH1 mRNA

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

G

NADPH oxidase 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NOX1 mRNA

NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236

G

neuronal pentraxin 1

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of NPTX1 mRNA

NCBI chr10:104,811,107...104,820,358
Ensembl chr10:104,811,403...104,820,367

G

neuropeptide Y

decreases expression

Sodium Glutamate results in decreased expression of NPY mRNA

PMID:9794456 PMID:19151514

NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495

G

NAD(P)H quinone dehydrogenase 1

multiple interactions
decreases expression
increases expression

[Plant Extracts co-treated with Sodium Glutamate] results in increased activity of NQO1 protein; Sodium Glutamate results in increased expression of and results in increased activity of NQO1 protein; Tea inhibits the reaction [Sodium Glutamate results in decreased expression of NQO1 mRNA]
Sodium Glutamate results in increased expression of NQO1 mRNA

PMID:25473020 PMID:26319613 PMID:29679905

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 0, group B, member 2

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of NR0B2 mRNA
[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of NR0B2 mRNA

NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609

G

nuclear receptor subfamily 1, group H, member 3

increases expression
multiple interactions

Sodium Glutamate results in increased expression of NR1H3 mRNA
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Sodium Glutamate results in increased expression of NR1H3 mRNA]

NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722

G

nuclear receptor subfamily 1, group I, member 3

multiple interactions
increases expression

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NR1I3 mRNA; [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of NR1I3 mRNA
Sodium Glutamate results in increased expression of NR1I3 mRNA

PMID:20111022 PMID:23783067

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

nuclear receptor subfamily 4, group A, member 2

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of NR4A2 mRNA

NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877

G

NSE1 homolog, SMC5-SMC6 complex component

multiple interactions
increases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of NSMCE1 mRNA
Sodium Glutamate results in increased expression of NSMCE1 mRNA

NCBI chr 1:180,030,355...180,058,541
Ensembl chr 1:180,030,160...180,058,417

G

nudix hydrolase 17

increases expression

Sodium Glutamate results in increased expression of NUDT17 mRNA

NCBI chr 2:184,241,468...184,243,960
Ensembl chr 2:184,241,468...184,243,960

G

nudix hydrolase 2

increases expression

Sodium Glutamate results in increased expression of NUDT2 mRNA

NCBI chr 5:56,628,265...56,643,104
Ensembl chr 5:56,628,265...56,643,104

G

nudix hydrolase 7

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of NUDT7 mRNA

NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081

G

one cut homeobox 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ONECUT1 mRNA

NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277

G

opsin 1, medium wave sensitive

increases expression

Sodium Glutamate results in increased expression of OPN1MW mRNA

NCBI chr X:151,905,056...151,925,419
Ensembl chr X:151,905,096...151,925,388

G

olfactory receptor family 4 subfamily C member 11

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of OR4C11 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of OR4C11 mRNA

NCBI chr 3:74,598,809...74,599,732
Ensembl chr 3:74,579,912...74,603,428

G

oxysterol binding protein-like 6

decreases expression

Sodium Glutamate results in decreased expression of OSBPL6 mRNA

NCBI chr 3:61,343,776...61,541,170
Ensembl chr 3:61,343,809...61,537,102

G

p21 (RAC1) activated kinase 1

decreases expression

Sodium Glutamate results in decreased expression of PAK1 mRNA

NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383

G

progestin and adipoQ receptor family member 4

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PAQR4 mRNA

NCBI chr10:12,758,970...12,762,649
Ensembl chr10:12,758,972...12,762,584

G

progestin and adipoQ receptor family member 5

increases expression

Sodium Glutamate results in increased expression of PAQR5 mRNA

NCBI chr 8:62,431,867...62,513,688
Ensembl chr 8:62,431,867...62,513,688

G

progestin and adipoQ receptor family member 7

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PAQR7 mRNA

NCBI chr 5:146,709,159...146,720,577
Ensembl chr 5:146,708,900...146,720,673

G

progestin and adipoQ receptor family member 9

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PAQR9 mRNA

NCBI chr 8:96,114,249...96,116,546

G

photoreceptor cilium actin regulator

increases expression

Sodium Glutamate results in increased expression of PCARE mRNA

NCBI chr 6:23,749,700...23,758,424
Ensembl chr 6:23,749,757...23,758,169

G

protocadherin 8

increases expression

Sodium Glutamate results in increased expression of PCDH8 mRNA

NCBI chr15:55,198,470...55,203,039
Ensembl chr15:55,198,459...55,205,872

G

phosphoenolpyruvate carboxykinase 1

multiple interactions
increases expression

[Sodium Glutamate co-treated with Bezafibrate] results in decreased expression of PCK1 mRNA; Resveratrol inhibits the reaction [Sodium Glutamate results in increased expression of PCK1 mRNA]

PMID:21549692 PMID:28708105

NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191

G

procollagen C-endopeptidase enhancer

decreases expression

Sodium Glutamate results in decreased expression of PCOLCE mRNA

NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508

G

phosphodiesterase 3B

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of PDE3B mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PDE3B mRNA

NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334

G

phosphodiesterase 6A

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of PDE6A mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in decreased expression of PDE6A mRNA

NCBI chr18:54,676,863...54,748,640
Ensembl chr18:54,676,863...54,748,816

G

phosphodiesterase 6C

increases expression

Sodium Glutamate results in increased expression of PDE6C mRNA

NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315

G

platelet derived growth factor receptor alpha

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of PDGFRA mRNA

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

G

platelet-derived growth factor receptor-like

affects expression

Sodium Glutamate affects the expression of PDGFRL mRNA

NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850

G

pyruvate dehydrogenase E1 subunit alpha 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PDHA2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PDHA2 mRNA

NCBI chr 2:229,872,300...229,873,848

G

pyruvate dehydrogenase E1 subunit beta

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PDHB mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PDHB mRNA

NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500

G

pyruvate dehydrogenase complex, component X

multiple interactions
increases expression

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of PDHX mRNA
Sodium Glutamate results in increased expression of PDHX mRNA

NCBI chr 3:89,372,248...89,431,779
Ensembl chr 3:89,371,497...89,431,773

G

protein disulfide isomerase family A, member 4

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of PDIA4 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of PDIA4 mRNA; [Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PDIA4 mRNA

PMID:20111022 PMID:22078008

NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107

G

pyruvate dehydrogenase kinase 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PDK1 mRNA

NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038

G

pyruvate dehydrogenase kinase 4

increases expression
multiple interactions

Sodium Glutamate results in increased expression of PDK4 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of PDK4 mRNA

NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850

G

peroxisomal trans-2-enoyl-CoA reductase

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PECR mRNA

NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511

G

pellino E3 ubiquitin protein ligase 1

decreases expression

Sodium Glutamate results in decreased expression of PELI1 mRNA

NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285

G

phosphatidylethanolamine N-methyltransferase

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PEMT mRNA

NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013

G

peptidase D

decreases expression

Sodium Glutamate results in decreased expression of PEPD mRNA

NCBI chr 1:87,536,650...87,681,233
Ensembl chr 1:87,536,609...87,681,231

G

peroxisomal biogenesis factor 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PEX1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PEX1 mRNA

NCBI chr 4:30,519,950...30,558,953
Ensembl chr 4:30,519,955...30,558,921

G

peroxisomal biogenesis factor 11 alpha

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PEX11A mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PEX11A mRNA

NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172

G

peroxisomal biogenesis factor 13

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PEX13 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PEX13 mRNA

NCBI chr14:97,602,829...97,621,233
Ensembl chr14:97,603,539...97,621,262

G

peroxisomal biogenesis factor 5

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PEX5 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PEX5 mRNA

NCBI chr 4:157,270,671...157,296,432
Ensembl chr 4:157,270,672...157,296,431

G

peroxisomal biogenesis factor 7

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PEX7 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PEX7 mRNA

NCBI chr 1:14,582,698...14,646,686
Ensembl chr 1:14,582,699...14,646,748

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PFKFB2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PFKFB2 mRNA

NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PFKFB4 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PFKFB4 mRNA

NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634

G

phosphoglycerate mutase 1

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PGAM1 mRNA

NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452

G

phosphorylase kinase regulatory subunit beta

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PHKB mRNA

NCBI chr19:21,013,719...21,210,671
Ensembl chr19:21,025,733...21,210,633

G

PH domain and leucine rich repeat protein phosphatase 2

multiple interactions
decreases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PHLPP2 mRNA
Sodium Glutamate results in decreased expression of PHLPP2 mRNA

NCBI chr19:37,835,125...37,901,804
Ensembl chr19:37,835,125...37,905,513

G

peptidase inhibitor 16

decreases expression

Sodium Glutamate results in decreased expression of PI16 mRNA

NCBI chr20:7,376,073...7,385,386
Ensembl chr20:7,376,126...7,385,383

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

multiple interactions
increases expression

Semaxinib inhibits the reaction [Sodium Glutamate results in increased expression of PIK3CA protein]

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

G

protein kinase domain containing, cytoplasmic

decreases expression

Sodium Glutamate results in decreased expression of PKDCC mRNA

NCBI chr 6:11,455,686...11,465,002
Ensembl chr 6:11,455,686...11,465,556

G

pyruvate kinase L/R

increases expression

Sodium Glutamate results in increased expression of PKLR mRNA

NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870

G

phospholipase A2, group XIIB

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of PLA2G12B mRNA

NCBI chr20:27,369,196...27,389,517
Ensembl chr20:27,370,266...27,388,743

G

phospholipase A2, group XV

increases expression

Sodium Glutamate results in increased expression of PLA2G15 mRNA

NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063

G

phospholipase A2, group IIE

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PLA2G2E mRNA

NCBI chr 5:151,121,363...151,127,147
Ensembl chr 5:151,121,439...151,126,821

G

PLAG1 like zinc finger 1

decreases expression

Sodium Glutamate results in decreased expression of PLAGL1 mRNA

NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228

G

plasminogen activator, urokinase receptor

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of PLAUR mRNA

NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595

G

phospholipase B domain containing 1

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PLBD1 mRNA

NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277

G

phospholipase C, gamma 1

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of PLCG1 mRNA

NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330

G

phospholipase D2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PLD2 mRNA

NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808

G

pleckstrin homology, MyTH4 and FERM domain containing H1

increases expression

Sodium Glutamate results in increased expression of PLEKHH1 mRNA

NCBI chr 6:97,839,288...97,888,712
Ensembl chr 6:97,839,288...97,888,709

G

phospholipid phosphatase related 1

increases expression

Sodium Glutamate results in increased expression of PLPPR1 mRNA

NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835

G

plexin D1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PLXND1 mRNA

NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244

G

polyamine-modulated factor 1

increases expression
multiple interactions

Sodium Glutamate results in increased expression of PMF1 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of PMF1 mRNA

NCBI chr 2:173,848,074...173,868,272
Ensembl chr 2:173,848,074...173,868,270

G

phosphomevalonate kinase

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PMVK mRNA

NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364

G

pancreatic lipase

increases expression

Sodium Glutamate results in increased expression of PNLIP mRNA

NCBI chr 1:257,774,012...257,811,656
Ensembl chr 1:257,798,581...257,811,654

G

patatin-like phospholipase domain containing 3

increases expression

Sodium Glutamate results in increased expression of PNPLA3 mRNA

NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077

G

DNA polymerase gamma, catalytic subunit

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of POLG mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of POLG mRNA

NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567

G

DNA polymerase iota

increases expression

Sodium Glutamate results in increased expression of POLI mRNA

NCBI chr18:64,116,774...64,134,373
Ensembl chr18:64,116,774...64,163,418

G

proopiomelanocortin

decreases secretion
increases expression
decreases expression

Sodium Glutamate results in decreased secretion of POMC protein
Sodium Glutamate results in increased expression of POMC mRNA; Sodium Glutamate results in increased expression of POMC protein
Sodium Glutamate results in decreased expression of POMC mRNA

PMID:8071649 PMID:9662721 PMID:9794456

NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664

G

peroxisome proliferator activated receptor alpha

decreases expression
increases expression
multiple interactions

Sodium Glutamate results in decreased expression of PPARA mRNA
Sodium Glutamate results in increased expression of PPARA mRNA
[Bezafibrate co-treated with Sodium Glutamate] results in increased expression of PPARA mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PPARA mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PPARA mRNA

PMID:21205225 PMID:21549692 PMID:21999347 PMID:23783067

NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor delta

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PPARD mRNA

NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968

G

peroxisome proliferator-activated receptor gamma

multiple interactions
affects response to substance
increases expression

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PPARG mRNA
PPARG protein affects the susceptibility to Sodium Glutamate
Sodium Glutamate results in increased expression of PPARG mRNA

PMID:15231871 PMID:21205225 PMID:23783067

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

PPARG coactivator 1 alpha

multiple interactions
decreases expression
increases expression

[Taurine co-treated with Sodium Glutamate] results in increased expression of PPARGC1A mRNA; [Taurine co-treated with Sodium Glutamate] results in increased expression of PPARGC1A protein; Taurine promotes the reaction [Sodium Glutamate results in increased expression of PPARGC1A protein]
Sodium Glutamate results in decreased expression of PPARGC1A mRNA
[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PPARGC1A mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PPARGC1A mRNA; [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of PPARGC1A mRNA; [Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of PPARGC1A mRNA; Sodium Glutamate results in increased expression of and results in increased acetylation of PPARGC1A protein; SRT1720 inhibits the reaction [Sodium Glutamate results in increased acetylation of PPARGC1A protein]; SRT1720 promotes the reaction [Sodium Glutamate results in increased expression of PPARGC1A protein]

PMID:19001666 PMID:19724016 PMID:20111022 PMID:23783067 PMID:25211138

NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656

G

protein phosphatase 3, regulatory subunit B, alpha

increases expression
multiple interactions

Sodium Glutamate results in increased expression of PPP3R1 mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PPP3R1 mRNA

NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907

G

PPARG related coactivator 1

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of PPRC1 mRNA

NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587

G

peroxiredoxin 2

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of PRDX2 mRNA

NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194

G

peroxiredoxin 5

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PRDX5 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of PRDX5 mRNA

NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268

G

proteoglycan 4

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of PRG4 mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PRG4 mRNA

NCBI chr13:62,487,257...62,504,657
Ensembl chr13:62,487,257...62,504,119

G

serine protease 23

decreases expression

Sodium Glutamate results in decreased expression of PRSS23 mRNA

NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091

G

phosphoserine aminotransferase 1

increases expression

Sodium Glutamate results in increased expression of PSAT1 mRNA

NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682

G

proteasome 26S subunit, ATPase 2

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PSMC2 mRNA

NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185

G

proteasome 26S subunit, non-ATPase 14

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PSMD14 mRNA

NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076

G

proteasome 26S subunit, non-ATPase 9

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PSMD9 mRNA

NCBI chr12:33,337,182...33,357,468

G

platelet-activating factor receptor

decreases expression

Sodium Glutamate results in decreased expression of PTAFR mRNA

NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251

G

prostaglandin E receptor 3

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PTGER3 mRNA

NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434

G

parathymosin

increases expression

Sodium Glutamate results in increased expression of PTMS mRNA

NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009

G

Pvt1 oncogene

increases expression

Sodium Glutamate results in increased expression of PVT1 mRNA

NCBI chr 7:93,656,528...93,879,938

G

PWWP domain containing 3B

increases expression

Sodium Glutamate results in increased expression of PWWP3B mRNA

NCBI chr X:102,804,416...102,838,580
Ensembl chr X:102,804,520...102,838,574

G

peroxisomal membrane protein 2

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of PXMP2 mRNA

NCBI chr12:46,394,051...46,404,561
Ensembl chr12:46,394,193...46,404,557

G

peroxisomal membrane protein 4

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PXMP4 mRNA

NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651

G

retinoic acid induced 14

decreases expression

Sodium Glutamate results in decreased expression of RAI14 mRNA

NCBI chr 2:59,546,284...59,682,687
Ensembl chr 2:59,546,284...59,681,971

G

RAN, member RAS oncogene family

increases expression
multiple interactions

Sodium Glutamate results in increased expression of RAN mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of RAN mRNA

NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276

G

Rap guanine nucleotide exchange factor 6

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of RAPGEF6 mRNA

NCBI chr10:38,655,854...38,824,227
Ensembl chr10:38,655,867...38,823,211

G

retinoic acid receptor, beta

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of RARB mRNA

NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288

G

RAS guanyl releasing protein 2

increases expression

Sodium Glutamate results in increased expression of RASGRP2 mRNA

NCBI chr 1:203,705,777...203,722,993
Ensembl chr 1:203,707,481...203,722,993

G

Ras association domain family member 7

affects expression

Sodium Glutamate affects the expression of RASSF7 mRNA

NCBI chr 1:196,319,600...196,323,787
Ensembl chr 1:196,320,902...196,323,770

G

RB transcriptional corepressor 1

increases expression
increases phosphorylation

Sodium Glutamate results in increased expression of RB1 mRNA
Sodium Glutamate results in increased phosphorylation of RB1 protein

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RNA binding motif protein 4

increases expression

Sodium Glutamate results in increased expression of RBM4 mRNA

NCBI chr 1:202,078,442...202,087,506
Ensembl chr 1:202,085,279...202,105,380

G

retinol binding protein 4

increases expression
multiple interactions

Sodium Glutamate results in increased expression of RBP4 protein
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of RBP4 protein

NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399

G

recombination signal binding protein for immunoglobulin kappa J region-like

increases expression

Sodium Glutamate results in increased expression of RBPJL mRNA

NCBI chr 3:153,134,044...153,147,421
Ensembl chr 3:153,134,140...153,146,513

G

reticulocalbin 1

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of RCN1 mRNA

NCBI chr 3:91,841,052...91,855,295
Ensembl chr 3:91,841,052...91,855,295

G

reticulocalbin 3

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of RCN3 mRNA

NCBI chr 1:95,564,503...95,573,762
Ensembl chr 1:95,564,380...95,573,725

G

retinol dehydrogenase 9

increases expression

Sodium Glutamate results in increased expression of RDH9 mRNA

NCBI chr 7:63,642,305...63,645,149

G

RecQ like helicase

increases expression

Sodium Glutamate results in increased expression of RECQL mRNA

NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945

G

RELA proto-oncogene, NF-kB subunit

multiple interactions
increases expression

[Fenofibrate co-treated with Sodium Glutamate] results in increased expression of RELA protein
Resveratrol inhibits the reaction [Sodium Glutamate results in increased expression of RELA mRNA]

PMID:21999347 PMID:28708105

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RE1-silencing transcription factor

increases expression
multiple interactions

Sodium Glutamate results in increased expression of REST mRNA
SB 203580 inhibits the reaction [Sodium Glutamate results in increased expression of REST mRNA]

NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354

G

resistin

increases expression
decreases expression
affects expression
increases secretion
multiple interactions

Sodium Glutamate results in increased expression of RETN mRNA; Sodium Glutamate results in increased expression of RETN protein
Sodium Glutamate results in decreased expression of RETN; Sodium Glutamate results in decreased expression of RETN mRNA
Sodium Glutamate affects the expression of RETN protein
Sodium Glutamate results in increased secretion of RETN protein
Glycine affects the reaction [Sodium Glutamate affects the expression of RETN protein]; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased expression of RETN mRNA]; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased secretion of RETN protein]; Plant Extracts inhibits the reaction [Sodium Glutamate results in increased expression of RETN mRNA]

PMID:12208498 PMID:15809509 PMID:18930730 PMID:21205225 PMID:27918843

NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620

G

RNA exonuclease 1 homolog

decreases expression

Sodium Glutamate results in decreased expression of REXO1 mRNA

NCBI chr 7:9,154,050...9,174,035
Ensembl chr 7:9,154,061...9,173,454

G

regulator of G-protein signaling 3

increases expression

Sodium Glutamate results in increased expression of RGS3 mRNA

NCBI chr 5:76,022,038...76,161,895
Ensembl chr 5:76,022,001...76,161,894

G

reactive intermediate imine deaminase A homolog

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of RIDA mRNA

NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716

G

ribosomal oxygenase 2

decreases expression

Sodium Glutamate results in decreased expression of RIOX2 mRNA

NCBI chr11:40,861,365...40,884,782
Ensembl chr11:40,860,774...40,884,574

G

Rho-associated coiled-coil containing protein kinase 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ROCK1 mRNA

NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571

G

reactive oxygen species modulator 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of ROMO1 mRNA

NCBI chr 3:144,659,709...144,661,310
Ensembl chr 3:144,659,826...144,661,310

G

ribosomal protein S27-like

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of RPS27L mRNA

NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418

G

ribosomal protein S29

increases expression

Sodium Glutamate results in increased expression of RPS29 mRNA

NCBI chr 6:87,635,229...87,636,627
Ensembl chr 6:87,635,230...87,636,636

G

RAS related 2

multiple interactions
increases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of RRAS2 mRNA
Sodium Glutamate results in increased expression of RRAS2 mRNA

NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111

G

ribosomal RNA processing 9, U3 small nucleolar RNA binding protein

increases expression

Sodium Glutamate results in increased expression of RRP9 mRNA

NCBI chr 8:107,116,411...107,126,123
Ensembl chr 8:107,117,471...107,126,123

G

RT1 class II, locus Db1

decreases expression

Sodium Glutamate results in decreased expression of RT1-DB1 mRNA

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

G

S100 calcium binding protein A13

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of S100A13 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of S100A13 mRNA

NCBI chr 2:175,999,439...176,005,933

G

S100 calcium binding protein A8

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of S100A8 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of S100A8 mRNA

NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643

G

sterile alpha motif domain containing 4B

decreases expression

Sodium Glutamate results in decreased expression of SAMD4B mRNA

NCBI chr 1:83,689,413...83,728,652
Ensembl chr 1:83,689,413...83,713,853

G

scavenger receptor class B, member 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SCARB1 mRNA

NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647

G

small Cajal body-specific RNA 17

increases expression

Sodium Glutamate results in increased expression of SCARNA17 mRNA

NCBI chr18:68,344,475...68,344,553
Ensembl chr18:68,344,475...68,344,553

G

stearoyl-Coenzyme A desaturase 2

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] affects the expression of SCD2 mRNA
Sodium Glutamate results in increased expression of SCD2 mRNA

NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232

G

stearoyl-coenzyme A desaturase 4

increases expression
decreases expression
multiple interactions

Sodium Glutamate results in increased expression of SCD4 mRNA
Sodium Glutamate results in decreased expression of SCD4 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of SCD4 mRNA; [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SCD4 mRNA; [Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of SCD4 mRNA

PMID:19001666 PMID:20111022 PMID:22078008

NCBI chr 1:243,203,433...243,216,007
Ensembl chr 1:243,203,881...243,215,148

G

secretogranin V

increases expression

Sodium Glutamate results in increased expression of SCG5 mRNA

NCBI chr 3:100,544,101...100,588,558
Ensembl chr 3:100,544,099...100,588,463

G

sodium voltage-gated channel alpha subunit 9

decreases expression

Sodium Glutamate results in decreased expression of SCN9A mRNA

NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516

G

succinate dehydrogenase complex iron sulfur subunit B

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SDHB mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of SDHB mRNA

NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293

G

serine dehydratase

increases expression

Sodium Glutamate results in increased expression of SDS mRNA

NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203

G

serpin family B member 5

increases expression

Sodium Glutamate results in increased expression of SERPINB5 mRNA

NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756

G

stratifin

decreases expression

Sodium Glutamate results in decreased expression of SFN mRNA

NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314

G

sphingosine-1-phosphate phosphatase 1

increases expression

Sodium Glutamate results in increased expression of SGPP1 mRNA

NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534

G

salt-inducible kinase 1

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of SIK1 mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of SIK1 mRNA

NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991

G

sirtuin 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SIRT1 mRNA; [Resveratrol co-treated with Sodium Glutamate] results in increased expression of SIRT1 protein

PMID:23783067 PMID:28708105

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

G

sirtuin 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SIRT2 mRNA

NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975

G

Ski proto-oncogene

decreases expression

Sodium Glutamate results in decreased expression of SKI mRNA

NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733

G

solute carrier family 13 member 2

increases expression

Sodium Glutamate results in increased expression of SLC13A2 mRNA

NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127

G

solute carrier family 22 member 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SLC22A1 mRNA

NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678

G

solute carrier family 22, member 18

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SLC22A18 mRNA

NCBI chr 1:198,670,626...198,694,977
Ensembl chr 1:198,671,731...198,694,975

G

solute carrier family 25 member 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SLC25A1 mRNA

NCBI chr11:83,055,764...83,058,781
Ensembl chr11:83,055,748...83,058,781

G

solute carrier family 25 member 10

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SLC25A10 mRNA

NCBI chr10:105,765,598...105,775,159
Ensembl chr10:105,765,372...105,773,556

G

solute carrier family 25 member 12

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of SLC25A12 mRNA

NCBI chr 3:56,097,166...56,191,841
Ensembl chr 3:56,097,269...56,192,100

G

solute carrier family 25 member 25

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of SLC25A25 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of SLC25A25 mRNA

NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216

G

solute carrier family 25 member 33

multiple interactions
decreases expression

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of SLC25A33 mRNA
Sodium Glutamate results in decreased expression of SLC25A33 mRNA

NCBI chr 5:160,195,040...160,219,961
Ensembl chr 5:160,195,042...160,219,961

G

solute carrier family 26 member 4

increases expression

Sodium Glutamate results in increased expression of SLC26A4 mRNA

NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703

G

solute carrier family 27 member 1

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SLC27A1 mRNA

NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063

G

solute carrier family 28 member 1

multiple interactions
decreases expression

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in decreased expression of SLC28A1 mRNA
Sodium Glutamate results in decreased expression of SLC28A1 mRNA

NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464

G

solute carrier family 2 member 1

multiple interactions

[Rosiglitazone co-treated with Sodium Glutamate] results in decreased expression of SLC2A1 mRNA; [Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of SLC2A1 mRNA

PMID:18048028 PMID:19001666

NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 2 member 12

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SLC2A12 mRNA

NCBI chr 1:22,803,068...22,862,204
Ensembl chr 1:22,804,418...22,860,971

G

solute carrier family 2 member 2

multiple interactions
increases expression

Resveratrol inhibits the reaction [Sodium Glutamate results in increased expression of SLC2A2 mRNA]; Resveratrol inhibits the reaction [Sodium Glutamate results in increased expression of SLC2A2 protein]
Sodium Glutamate results in increased expression of SLC2A2 mRNA; Sodium Glutamate results in increased expression of SLC2A2 protein

NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933

G

solute carrier family 2 member 4

affects expression
decreases expression
multiple interactions
increases expression

Sodium Glutamate affects the expression of SLC2A4 mRNA; Sodium Glutamate affects the expression of SLC2A4 protein
Sodium Glutamate results in decreased expression of SLC2A4 protein
Atorvastatin inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 protein]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of SLC2A4 mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of SLC2A4 protein]; Resveratrol inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 mRNA]; Resveratrol inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 protein]; Tea inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 protein]
Carbenoxolone affects the reaction [Sodium Glutamate affects the expression of SLC2A4 mRNA]; Carbenoxolone affects the reaction [Sodium Glutamate affects the expression of SLC2A4 protein]
Sodium Glutamate results in decreased expression of SLC2A4 mRNA; Sodium Glutamate results in decreased expression of SLC2A4 protein

PMID:11319642 PMID:19800637 PMID:22415589 PMID:25834641 PMID:28708105 More...

NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565

G

solute carrier family 2 member 8

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SLC2A8 mRNA

NCBI chr 3:16,274,918...16,284,536
Ensembl chr 3:16,274,925...16,284,464

G

solute carrier family 35, member B1

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of SLC35B1 mRNA

NCBI chr10:80,327,921...80,335,279
Ensembl chr10:80,327,945...80,335,274

G

solute carrier family 36 member 2

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SLC36A2 mRNA

NCBI chr10:39,278,002...39,306,082
Ensembl chr10:39,278,046...39,306,082

G

solute carrier family 38, member 4

increases expression
multiple interactions

Sodium Glutamate results in increased expression of SLC38A4 mRNA
[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of SLC38A4 mRNA

NCBI chr 7:128,142,866...128,203,000
Ensembl chr 7:128,144,807...128,202,995

G

solute carrier family 45, member 2

increases expression

Sodium Glutamate results in increased expression of SLC45A2 mRNA

NCBI chr 2:59,963,599...59,996,408
Ensembl chr 2:59,963,706...59,996,317

G

solute carrier family 4 member 1 (Diego blood group)

decreases expression

Sodium Glutamate results in decreased expression of SLC4A1 mRNA

NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117

G

solute carrier family 4 member 2

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SLC4A2 mRNA

NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965

G

solute carrier family 4 member 4

decreases expression

Sodium Glutamate results in decreased expression of SLC4A4 mRNA

NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883

G

solute carrier family 6 member 1

decreases expression

Sodium Glutamate results in decreased expression of SLC6A1 mRNA

NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293

G

solute carrier family 6 member 2

increases expression

Sodium Glutamate results in increased expression of SLC6A2 mRNA

NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357

G

solute carrier family 8 member A1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SLC8A1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of SLC8A1 mRNA

NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628

G

solute carrier family 8 member A3

increases expression

Sodium Glutamate results in increased expression of SLC8A3 mRNA; Sodium Glutamate results in increased expression of SLC8A3 protein

NCBI chr 6:100,874,359...101,007,989
Ensembl chr 6:100,874,369...101,007,508

G

secretory leukocyte peptidase inhibitor

increases expression

Sodium Glutamate results in increased expression of SLPI mRNA

NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453

G

SMAD family member 4

decreases expression

Sodium Glutamate results in decreased expression of SMAD4 mRNA

NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438

G

small integral membrane protein 3

increases expression

Sodium Glutamate results in increased expression of SMIM3 mRNA

NCBI chr18:53,930,019...53,982,339
Ensembl chr18:53,930,020...53,957,416

G

small nuclear ribonucleoprotein U11/U12 subunit 35

increases expression

Sodium Glutamate results in increased expression of SNRNP35 mRNA

NCBI chr12:32,112,032...32,119,829
Ensembl chr12:32,110,993...32,122,660

G

suppressor of cytokine signaling 2

multiple interactions
decreases expression

Sodium Glutamate inhibits the reaction [GH1 protein results in decreased expression of SOCS2 mRNA]; Sodium Glutamate inhibits the reaction [GH1 protein results in increased expression of SOCS2 mRNA]; Sodium Glutamate inhibits the reaction [GH1 protein results in increased expression of SOCS2 protein]
Sodium Glutamate results in decreased expression of SOCS2 mRNA; Sodium Glutamate results in decreased expression of SOCS2 protein

NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548

G

suppressor of cytokine signaling 3

increases expression

Sodium Glutamate results in increased expression of SOCS3 protein

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

G

superoxide dismutase 1

decreases expression
multiple interactions
increases expression

Sodium Glutamate results in decreased expression of SOD1 mRNA
SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of SOD1 mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of SOD1 protein]
Sodium Glutamate results in increased expression of SOD1 mRNA; Sodium Glutamate results in increased expression of SOD1 protein

PMID:19724016 PMID:30733785

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

sortilin related receptor 1

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SORL1 mRNA
Sodium Glutamate results in increased expression of SORL1 mRNA

NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513

G

Sp1 transcription factor

increases expression

Sodium Glutamate results in increased expression of SP1 mRNA

NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961

G

small regulatory polypeptide of amino acid response

increases expression

Sodium Glutamate results in increased expression of SPAAR mRNA

NCBI chr 5:57,985,423...57,987,482

G

spondin 2

decreases expression

Sodium Glutamate results in decreased expression of SPON2 mRNA

NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996

G

S1 RNA binding domain 1

increases expression

Sodium Glutamate results in increased expression of SRBD1 mRNA

NCBI chr 6:8,473,591...8,664,544
Ensembl chr 6:8,475,542...8,664,544

G

sterol regulatory element binding transcription factor 1

multiple interactions
increases expression
affects expression
decreases expression

Carbenoxolone affects the reaction [Sodium Glutamate affects the expression of SREBF1 mRNA]
Sodium Glutamate results in increased expression of SREBF1 mRNA; Sodium Glutamate results in increased expression of SREBF1 protein
Sodium Glutamate results in decreased expression of SREBF1 mRNA
3-(4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-ylcarbonyl)thiazolidine affects the reaction [[Dietary Fats co-treated with Sodium Glutamate] affects the expression of SREBF1 mRNA]; [Dietary Fats co-treated with Sodium Glutamate] affects the expression of SREBF1 mRNA; [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SREBF1 mRNA; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of SREBF1 mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of SREBF1 protein]

PMID:19001666 PMID:19724016 PMID:26092479 PMID:26670228 PMID:31077719

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

G

sterol regulatory element binding transcription factor 2

multiple interactions
increases expression
decreases expression

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SREBF2 mRNA; [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of SREBF2 mRNA
Sodium Glutamate results in increased expression of SREBF2 mRNA
Sodium Glutamate results in decreased expression of SREBF2 mRNA

PMID:20111022 PMID:22078008 PMID:23783067

NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848

G

serine/arginine repetitive matrix 3

increases expression

Sodium Glutamate results in increased expression of SRRM3 mRNA

NCBI chr12:20,808,878...20,878,557
Ensembl chr12:20,809,089...20,878,505

G

SCO-spondin

increases expression

Sodium Glutamate results in increased expression of SSPO mRNA

NCBI chr 4:77,394,915...77,450,526
Ensembl chr 4:77,397,059...77,450,412

G

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

multiple interactions

[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of ST6GALNAC4 mRNA

NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243

G

signal transducer and activator of transcription 2

increases expression

Sodium Glutamate results in increased expression of STAT2 mRNA

NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967

G

signal transducer and activator of transcription 3

multiple interactions
decreases phosphorylation

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of STAT3 mRNA
Sodium Glutamate results in decreased phosphorylation of STAT3 protein

PMID:23783067 PMID:24502529

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

serine/threonine kinase 26

multiple interactions
increases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in decreased expression of STK26 mRNA
Sodium Glutamate results in increased expression of STK26 mRNA

NCBI chr X:130,325,064...130,375,674
Ensembl chr X:130,310,885...130,374,291

G

serine/threonine kinase 35

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of STK35 mRNA

NCBI chr 3:117,016,819...117,049,131
Ensembl chr 3:117,016,950...117,048,066

G

serine/threonine kinase 36

increases expression

Sodium Glutamate results in increased expression of STK36 mRNA

NCBI chr 9:76,176,922...76,204,423
Ensembl chr 9:76,176,920...76,204,422

G

syntaxin 2

increases expression

Sodium Glutamate results in increased expression of STX2 mRNA

NCBI chr12:27,678,744...27,714,751
Ensembl chr12:27,689,819...27,714,751

G

SURF1, cytochrome c oxidase assembly factor

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SURF1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of SURF1 mRNA

NCBI chr 3:10,241,793...10,244,686
Ensembl chr 3:10,241,837...10,263,315

G

synaptic Ras GTPase activating protein 1

decreases expression

Sodium Glutamate results in decreased expression of SYNGAP1 mRNA

NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672

G

tachykinin, precursor 1

decreases expression

Sodium Glutamate results in decreased expression of TAC1 mRNA

NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178

G

TATA-box binding protein associated factor, RNA polymerase I subunit A

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of TAF1A mRNA

NCBI chr13:95,012,160...95,048,131
Ensembl chr13:95,029,225...95,048,087

G

TAL bHLH transcription factor 2

multiple interactions
decreases expression

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of TAL2 mRNA
Sodium Glutamate results in decreased expression of TAL2 mRNA

NCBI chr 5:68,411,012...68,417,569
Ensembl chr 5:68,411,012...68,417,569

G

taste 1 receptor member 1

increases expression

Sodium Glutamate results in increased expression of TAS1R1 mRNA

NCBI chr 5:162,533,838...162,546,408
Ensembl chr 5:162,533,841...162,545,562

G

taste 1 receptor member 3

increases expression

Sodium Glutamate results in increased expression of TAS1R3 mRNA

NCBI chr 5:166,468,703...166,472,759
Ensembl chr 5:166,469,589...166,472,742

G

tyrosine aminotransferase

increases expression

Sodium Glutamate results in increased expression of TAT mRNA

NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031

G

transcription factor A, mitochondrial

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of TFAM mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of TFAM mRNA

NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292

G

transferrin receptor 2

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of TFR2 mRNA

NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591

G

transferrin receptor

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of TFRC mRNA

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

tyrosine hydroxylase

decreases activity
decreases expression

Sodium Glutamate results in decreased activity of TH protein
Sodium Glutamate results in decreased expression of TH mRNA

NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767

G

THAP domain containing 2

decreases expression

Sodium Glutamate results in decreased expression of THAP2 mRNA

NCBI chr 7:50,992,912...51,007,582
Ensembl chr 7:50,995,793...51,008,061

G

thrombospondin 1

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of THBS1 mRNA

NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440

G

TOR signaling pathway regulator

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of TIPRL mRNA

NCBI chr13:77,527,176...77,552,026
Ensembl chr13:77,527,176...77,552,074

G

transmembrane channel like 6

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of TMC6 mRNA

NCBI chr10:102,982,059...102,999,509
Ensembl chr10:102,971,229...102,998,960

G

transmembrane protein 106A

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of TMEM106A mRNA

NCBI chr10:86,506,908...86,515,915
Ensembl chr10:86,506,936...86,515,892

G

transmembrane protein 190

increases expression

Sodium Glutamate results in increased expression of TMEM190 mRNA

NCBI chr 1:69,062,709...69,064,938
Ensembl chr 1:69,062,366...69,065,238

G

transmembrane protein 260

increases expression

Sodium Glutamate results in increased expression of TMEM260 mRNA

NCBI chr15:21,734,119...21,804,049
Ensembl chr15:21,734,151...21,806,801

G

transmembrane protein 69

increases expression
multiple interactions

Sodium Glutamate results in increased expression of TMEM69 mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of TMEM69 mRNA

NCBI chr 5:130,004,888...130,008,466
Ensembl chr 5:130,004,901...130,010,655

G

transmembrane serine protease 11F

affects expression

Sodium Glutamate affects the expression of TMPRSS11F mRNA

NCBI chr14:21,492,896...21,534,792
Ensembl chr14:21,429,418...21,534,809

G

transmembrane serine protease 2

multiple interactions
increases expression

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of TMPRSS2 mRNA
Sodium Glutamate results in increased expression of TMPRSS2 mRNA

NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715

G

tumor necrosis factor

increases expression
affects expression
multiple interactions

Sodium Glutamate results in increased expression of TNF mRNA; Sodium Glutamate results in increased expression of TNF protein
Sodium Glutamate affects the expression of TNF mRNA
[Fats, Unsaturated co-treated with Sodium Glutamate] results in increased expression of TNF protein; [Sodium Glutamate co-treated with Aspartame] promotes the reaction [Fats, Unsaturated results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of TNF mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of TNF protein]; Glycine affects the reaction [Sodium Glutamate affects the expression of TNF mRNA]; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased expression of TNF mRNA]; Plant Extracts inhibits the reaction [Sodium Glutamate results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [Sodium Glutamate results in increased expression of TNF mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of TNF mRNA]; SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of TNF protein]
[Fenofibrate co-treated with Sodium Glutamate] results in increased expression of TNF protein

PMID:18930730 PMID:19724016 PMID:19800637 PMID:21205225 PMID:21999347 More...

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 1B

increases secretion
multiple interactions

Sodium Glutamate results in increased secretion of TNFRSF1B protein
Plant Extracts inhibits the reaction [Sodium Glutamate results in increased secretion of TNFRSF1B protein]

NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206

G

TNF receptor superfamily member 4

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of TNFRSF4 mRNA
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of TNFRSF4 mRNA

NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599

G

TNF superfamily member 14

increases expression

Sodium Glutamate results in increased expression of TNFSF14 mRNA

NCBI chr 9:2,068,295...2,073,128
Ensembl chr 9:2,069,104...2,073,216

G

target of myb1 membrane trafficking protein

increases expression

Sodium Glutamate results in increased expression of TOM1 mRNA

NCBI chr19:13,405,482...13,440,384
Ensembl chr19:13,405,501...13,440,384

G

torsin family 3, member A

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of TOR3A mRNA

NCBI chr13:68,769,893...68,798,738
Ensembl chr13:68,769,605...68,798,475

G

tumor protein p53

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of TRP53 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of TRP53 mRNA

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tryptophan hydroxylase 1

increases expression

Sodium Glutamate results in increased expression of TPH1 mRNA

NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344

G

tropomyosin 4

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of TPM4 mRNA

NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984

G

tubulin polymerization-promoting protein family member 3

decreases expression

Sodium Glutamate results in decreased expression of TPPP3 mRNA

NCBI chr19:33,345,897...33,349,610
Ensembl chr19:33,345,898...33,349,577

G

Traf3 interacting protein 2

decreases expression

Sodium Glutamate results in decreased expression of TRAF3IP2 mRNA

NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667

G

tribbles pseudokinase 1

decreases expression

Sodium Glutamate results in decreased expression of TRIB1 mRNA

NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731

G

tripartite motif-containing 25

increases expression

Sodium Glutamate results in increased expression of TRIM25 mRNA

NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257

G

transient receptor potential cation channel, subfamily V, member 5

increases expression

Sodium Glutamate results in increased expression of TRPV5 mRNA

NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745

G

tetraspanin 1

increases expression

Sodium Glutamate results in increased expression of TSPAN1 mRNA

NCBI chr 5:129,646,139...129,659,383
Ensembl chr 5:129,646,993...129,652,017

G

tetraspanin 6

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of TSPAN6 mRNA

NCBI chr X:97,092,394...97,099,659
Ensembl chr X:97,092,388...97,099,309

G

TELO2 interacting protein 2

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of TTI2 mRNA

NCBI chr16:60,980,665...60,988,587
Ensembl chr16:60,979,039...60,988,569

G

Tu translation elongation factor, mitochondrial

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of TUFM mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of TUFM mRNA

NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395

G

thioredoxin 1

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of TXN1 mRNA

NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629

G

thioredoxin reductase 1

decreases expression

Sodium Glutamate results in decreased expression of TXNRD1 mRNA

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

ubiquitin-conjugating enzyme E2I

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of UBE2I protein
Carbenoxolone inhibits the reaction [Sodium Glutamate results in decreased expression of UBE2I protein]

NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443

G

uridine-cytidine kinase 2

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of UCK2 mRNA

NCBI chr13:79,380,807...79,438,121
Ensembl chr13:79,383,846...79,438,352

G

uncoupling protein 2

multiple interactions

[Fenofibrate co-treated with Sodium Glutamate] results in increased expression of UCP2 mRNA
[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of UCP2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of UCP2 mRNA

PMID:21999347 PMID:23783067

NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611

G

unc-5 family C-terminal like

decreases expression

Sodium Glutamate results in decreased expression of UNC5CL mRNA

NCBI chr 9:12,528,109...12,543,382
Ensembl chr 9:12,528,246...12,542,233

G

unc-93 homolog A

increases expression

Sodium Glutamate results in increased expression of UNC93A mRNA

NCBI chr 1:52,973,143...53,029,578
Ensembl chr 1:52,980,724...53,029,663

G

ubiquinol-cytochrome c reductase, complex III subunit XI

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of UQCR11 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate] affects the expression of UQCR11 mRNA

NCBI chr 7:9,305,042...9,309,753
Ensembl chr 7:9,305,058...9,309,750

G

uroporphyrinogen decarboxylase

increases expression
multiple interactions

Sodium Glutamate results in increased expression of UROD mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of UROD mRNA

NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808

G

ubiquitin specific peptidase 54

multiple interactions

[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of USP54 mRNA

NCBI chr15:3,659,345...3,757,703
Ensembl chr15:3,659,240...3,757,711

G

versican

decreases expression
multiple interactions

Sodium Glutamate results in decreased expression of VCAN mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of VCAN mRNA

NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637

G

vascular endothelial growth factor A

increases expression
multiple interactions

Sodium Glutamate results in increased expression of VEGFA mRNA; Sodium Glutamate results in increased expression of VEGFA protein
[Semaxinib co-treated with Sodium Glutamate] results in increased expression of VEGFA protein

PMID:28755050 PMID:36732937

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

vascular endothelial growth factor B

decreases expression

Sodium Glutamate results in decreased expression of VEGFB protein

NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944

G

WD repeat and FYVE domain containing 2

increases expression

Sodium Glutamate results in increased expression of WDFY2 mRNA

NCBI chr15:37,083,842...37,209,559
Ensembl chr15:37,042,987...37,209,304

G

WAP four-disulfide core domain 5

increases expression

Sodium Glutamate results in increased expression of WFDC5 mRNA

NCBI chr 3:152,849,025...152,854,868
Ensembl chr 3:152,849,025...152,854,904

G

WNK lysine deficient protein kinase 3

increases expression
multiple interactions

Sodium Glutamate results in increased expression of WNK3 mRNA
[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of WNK3 mRNA

NCBI chr X:20,156,260...20,299,252
Ensembl chr X:20,157,041...20,296,821

G

xanthine dehydrogenase

multiple interactions

[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of XDH mRNA

NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268

G

YY1 associated factor 2

multiple interactions

[Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of YAF2 mRNA

NCBI chr 7:124,444,152...124,499,688
Ensembl chr 7:124,444,152...124,499,928

G

YY2 transcription factor

increases expression

Sodium Glutamate results in increased expression of YY2 mRNA

NCBI chr X:37,438,425...37,442,047
Ensembl chr X:37,410,811...37,464,430

G

zinc finger protein 13

increases expression

Sodium Glutamate results in increased expression of ZFP13 mRNA

NCBI chr10:12,615,455...12,623,615
Ensembl chr10:12,615,190...12,623,615

G

zinc finger protein 239

increases expression

Sodium Glutamate results in increased expression of ZFP239 mRNA

NCBI chr 4:151,029,431...151,039,283
Ensembl chr 4:151,029,405...151,039,529

G

zinc finger protein 362

decreases expression

Sodium Glutamate results in decreased expression of ZFP362 mRNA

NCBI chr 5:141,119,073...141,153,304
Ensembl chr 5:141,119,898...141,156,716

G

zinc finger protein 42

increases expression

Sodium Glutamate results in increased expression of ZFP42 mRNA

NCBI chr16:48,836,463...48,845,443
Ensembl chr16:48,836,648...48,845,401

G

zinc finger protein 423

decreases expression

Sodium Glutamate results in decreased expression of ZFP423 mRNA

NCBI chr19:19,111,213...19,407,373
Ensembl chr19:19,110,238...19,407,373

S-adenosyl-L-methioninate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adhesion G protein-coupled receptor E4

decreases expression

S-Adenosylmethionine results in decreased expression of ADGRE4 mRNA

NCBI chr 9:9,758,106...9,901,908
Ensembl chr 9:9,760,355...9,900,760

G

adhesion G protein-coupled receptor E5

decreases expression

S-Adenosylmethionine results in decreased expression of ADGRE5 mRNA

NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638

G

alpha-fetoprotein

multiple interactions
decreases expression

S-Adenosylmethionine inhibits the reaction [Dicarbethoxydihydrocollidine results in increased expression of AFP mRNA]
S-Adenosylmethionine results in decreased expression of AFP mRNA

NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480

G

aryl hydrocarbon receptor

decreases abundance
multiple interactions

AHR protein results in decreased abundance of S-Adenosylmethionine
PEMT protein promotes the reaction [AHR protein results in decreased abundance of S-Adenosylmethionine]

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

aminolevulinate dehydratase

increases activity

S-Adenosylmethionine results in increased activity of ALAD protein

NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474

G

5'-aminolevulinate synthase 2

multiple interactions

[S-Adenosylmethionine co-treated with Hemin] results in increased expression of ALAS2 mRNA; catechol inhibits the reaction [[S-Adenosylmethionine co-treated with Hemin] results in increased expression of ALAS2 mRNA]

NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519

G

amyloid beta precursor protein

increases secretion

S-Adenosylmethionine results in increased secretion of APP protein modified form

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

arsenite methyltransferase

multiple interactions
affects binding

Cysteine promotes the reaction [AS3MT protein binds to S-Adenosylmethionine]; Glutathione promotes the reaction [AS3MT protein binds to S-Adenosylmethionine]; S-Adenosylmethionine promotes the reaction [AS3MT protein binds to and results in increased methylation of arsenite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein binds to S-Adenosylmethionine]

PMID:22955273 PMID:24124590 PMID:25349987

NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872

G

activating transcription factor 3

increases expression

S-Adenosylmethionine results in increased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

ATPase copper transporting beta

multiple interactions

ATP7B protein mutant form promotes the reaction [Betaine results in increased abundance of S-Adenosylmethionine]

NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636

G

betaine-homocysteine S-methyltransferase 2

multiple interactions

S-Adenosylmethionine inhibits the reaction [BHMT2 protein results in increased metabolism of Vitamin U]

NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475

G

caspase 12

decreases expression

S-Adenosylmethionine results in decreased expression of CASP12 mRNA

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

G

caspase 3

multiple interactions
decreases activity

S-Adenosylmethionine inhibits the reaction [Ethanol results in increased activity of CASP3 protein]
S-Adenosylmethionine results in decreased activity of CASP3 protein

PMID:17869084 PMID:18571630

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

catalase

multiple interactions

S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased activity of CAT protein]

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

cellular communication network factor 1

multiple interactions

S-Adenosylmethionine inhibits the reaction [sodium arsenite results in decreased expression of CCN1 protein]; S-Adenosylmethionine inhibits the reaction [sodium arsenite results in decreased stability of CCN1 mRNA]

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cadherin 2

multiple interactions

S-Adenosylmethionine inhibits the reaction [sodium arsenite results in decreased expression of CDH2 protein]

NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167

G

collagen type I alpha 1 chain

decreases expression
multiple interactions

S-Adenosylmethionine results in decreased expression of COL1A1 mRNA
S-Adenosylmethionine inhibits the reaction [LEP protein results in increased expression of COL1A1 mRNA]

PMID:15983038 PMID:16996477

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type I alpha 2 chain

multiple interactions
decreases expression

S-Adenosylmethionine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]; S-Adenosylmethionine inhibits the reaction [SP1 protein binds to COL1A2 promoter]; S-Adenosylmethionine inhibits the reaction [TGFB1 protein binds to COL1A2 promoter]
S-Adenosylmethionine results in decreased expression of COL1A2 mRNA

PMID:8878782 PMID:15983038

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

catechol-O-methyltransferase

multiple interactions

[tolcapone results in decreased activity of COMT protein] inhibits the reaction [Levodopa results in increased abundance of S-Adenosylmethionine]

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

cytochrome c, somatic

multiple interactions

S-Adenosylmethionine inhibits the reaction [Acetaminophen affects the localization of CYCS protein]

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases activity
multiple interactions

S-Adenosylmethionine results in decreased activity of CYP2E1 protein
S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]; S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine]; S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Ethanol]
S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased expression of CYP2E1 protein]; S-Adenosylmethionine promotes the reaction [Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein]

PMID:15763544 PMID:15983038 PMID:22683606

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

dopa decarboxylase

multiple interactions

[Levodopa co-treated with DDC] results in increased abundance of S-Adenosylmethionine

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

discs large MAGUK scaffold protein 4

multiple interactions

S-Adenosylmethionine inhibits the reaction [Particulate Matter results in decreased expression of DLG4 protein]

NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153

G

DNA methyltransferase 1

multiple interactions

S-Adenosylmethionine inhibits the reaction [arsenic trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter]]; S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in decreased expression of DNMT1 protein]

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 alpha

multiple interactions

S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in decreased expression of DNMT3A protein]
S-Adenosylmethionine inhibits the reaction [Dicarbethoxydihydrocollidine results in increased expression of DNMT3A mRNA]

PMID:18098314 PMID:22558281

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

early growth response 1

multiple interactions

[S-Adenosylmethionine co-treated with Arsenic] affects the expression of EGR1 mRNA; [S-Adenosylmethionine inhibits the reaction [Arsenic results in decreased methylation of EGR1 promoter]] which results in decreased expression of EGR1 mRNA; S-Adenosylmethionine inhibits the reaction [Arsenic results in decreased methylation of EGR1 promoter]

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

estrogen receptor 1

multiple interactions

S-Adenosylmethionine inhibits the reaction [[arsenic trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA]; S-Adenosylmethionine inhibits the reaction [[arsenic trioxide results in increased expression of ESR1 protein] which results in increased expression of TFF1 mRNA]; S-Adenosylmethionine inhibits the reaction [arsenic trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter]]; S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in decreased methylation of ESR1 promoter]; S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in increased expression of ESR1 mRNA]; S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in increased expression of ESR1 protein]

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

Fc gamma receptor 1A

decreases expression

S-Adenosylmethionine results in decreased expression of FCGR1 mRNA

NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994

G

fibroblast growth factor 19

increases abundance

FGF19 protein results in increased abundance of S-Adenosylmethionine

NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287

G

fibrinogen-like 2

decreases expression

S-Adenosylmethionine results in decreased expression of FGL2 mRNA

NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207

G

guanylate binding protein 2

decreases expression

S-Adenosylmethionine results in decreased expression of GBP2 mRNA

NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions

S-Adenosylmethionine inhibits the reaction [Lithocholic Acid affects the expression of GCLC mRNA]; S-Adenosylmethionine promotes the reaction [Ursodeoxycholic Acid inhibits the reaction [Lithocholic Acid affects the expression of GCLC mRNA]]

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

growth regulating estrogen receptor binding 1

multiple interactions

S-Adenosylmethionine inhibits the reaction [[arsenic trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA]; S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in increased expression of GREB1 mRNA]

NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633

G

glutathione-disulfide reductase

multiple interactions

S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased activity of GSR protein]

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione synthetase

multiple interactions

S-Adenosylmethionine inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA]; S-Adenosylmethionine promotes the reaction [Ursodeoxycholic Acid inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA]]

NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198

G

glutathione S-transferase mu 2

multiple interactions

S-Adenosylmethionine inhibits the reaction [Dicarbethoxydihydrocollidine results in increased expression of GSTM2 mRNA]

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

heart and neural crest derivatives expressed 2

multiple interactions

[Progesterone co-treated with S-Adenosylmethionine] results in increased methylation of HAND2 promoter; S-Adenosylmethionine inhibits the reaction [Progesterone results in increased expression of HAND2 mRNA]

NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891

G

hemoglobin subunit beta

multiple interactions

[S-Adenosylmethionine co-treated with Hemin] results in increased expression of HBB mRNA; catechol inhibits the reaction [[S-Adenosylmethionine co-treated with Hemin] results in increased expression of HBB mRNA]

NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012

G

histone deacetylase 9

multiple interactions

S-Adenosylmethionine inhibits the reaction [Dicarbethoxydihydrocollidine results in increased expression of HDAC9 mRNA]

NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333

G

hydroxymethylbilane synthase

multiple interactions

[S-Adenosylmethionine co-treated with Hemin] results in increased expression of HMBS mRNA; catechol inhibits the reaction [[S-Adenosylmethionine co-treated with Hemin] results in increased expression of HMBS mRNA]

NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957

G

interferon-induced protein 44-like

decreases expression

S-Adenosylmethionine results in decreased expression of IFI44L mRNA

NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359

G

interferon gamma

multiple interactions

S-Adenosylmethionine inhibits the reaction [fumonisin B1 results in increased expression of IFNG mRNA]

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 1 beta

multiple interactions

S-Adenosylmethionine inhibits the reaction [Thioacetamide results in increased expression of IL1B protein]
S-Adenosylmethionine inhibits the reaction [fumonisin B1 results in increased expression of IL1B mRNA]

PMID:17080400 PMID:19822164

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

multiple interactions

S-Adenosylmethionine inhibits the reaction [fumonisin B1 results in increased expression of IL2 mRNA]

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 2 receptor subunit gamma

decreases expression

S-Adenosylmethionine results in decreased expression of IL2RG mRNA

NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823

G

interleukin 36, gamma

decreases expression

S-Adenosylmethionine results in decreased expression of IL36G mRNA

NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480

G

interleukin 6

multiple interactions

S-Adenosylmethionine inhibits the reaction [Thioacetamide results in increased expression of IL6 protein]
S-Adenosylmethionine inhibits the reaction [fumonisin B1 results in increased expression of IL6 mRNA]

PMID:17080400 PMID:19822164

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

KLF transcription factor 6

decreases expression
multiple interactions

S-Adenosylmethionine results in decreased expression of KLF6 mRNA
S-Adenosylmethionine inhibits the reaction [Dicarbethoxydihydrocollidine results in increased expression of KLF6 mRNA]

NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570

G

leptin

multiple interactions

S-Adenosylmethionine inhibits the reaction [LEP protein results in increased expression of COL1A1 mRNA]; S-Adenosylmethionine inhibits the reaction [Vitamin K 3 results in increased expression of LEP mRNA]

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

G

lymphotoxin beta

multiple interactions

S-Adenosylmethionine inhibits the reaction [fumonisin B1 results in increased expression of LTB mRNA]

NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381

G

MAF bZIP transcription factor

multiple interactions

S-Adenosylmethionine inhibits the reaction [Lithocholic Acid results in increased expression of MAF protein]; S-Adenosylmethionine promotes the reaction [Ursodeoxycholic Acid inhibits the reaction [Lithocholic Acid results in increased expression of MAF protein]]

NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365

G

MAF bZIP transcription factor G

multiple interactions

S-Adenosylmethionine inhibits the reaction [Lithocholic Acid results in increased expression of MAFG protein]; S-Adenosylmethionine promotes the reaction [Ursodeoxycholic Acid inhibits the reaction [Lithocholic Acid results in increased expression of MAFG protein]]

NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026

G

mitogen activated protein kinase 1

multiple interactions

S-Adenosylmethionine inhibits the reaction [TGFB1 protein results in increased phosphorylation of MAPK1 protein]
[1,2-linoleoylphosphatidylcholine co-treated with S-Adenosylmethionine] inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK1 protein]; S-Adenosylmethionine inhibits the reaction [TGFB1 protein promotes the reaction [SP1 protein binds to MAPK1 protein modified form]]

PMID:15983038 PMID:16996477

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions

S-Adenosylmethionine inhibits the reaction [TGFB1 protein results in increased phosphorylation of MAPK3 protein]
[1,2-linoleoylphosphatidylcholine co-treated with S-Adenosylmethionine] inhibits the reaction [Vitamin K 3 results in increased phosphorylation of MAPK3 protein]; S-Adenosylmethionine inhibits the reaction [TGFB1 protein promotes the reaction [SP1 protein binds to MAPK3 protein modified form]]

PMID:15983038 PMID:16996477

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

methionine adenosyltransferase 1A

affects abundance
increases chemical synthesis

MAT1A affects the abundance of S-Adenosylmethionine
MAT1A protein results in increased chemical synthesis of S-Adenosylmethionine

PMID:8373829 PMID:12060674

NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274

G

methionine adenosyltransferase 2A

increases chemical synthesis

MAT2A protein results in increased chemical synthesis of S-Adenosylmethionine

NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493

G

methyl-CpG binding domain protein 2

multiple interactions

S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in increased expression of MBD2 protein]

NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794

G

maternally expressed 3

multiple interactions

S-Adenosylmethionine inhibits the reaction [Arsenicals results in increased expression of MEG3 mRNA]

NCBI chr 6:128,491,808...128,524,010

G

matrix metallopeptidase 2

multiple interactions

S-Adenosylmethionine inhibits the reaction [sodium arsenite results in decreased expression of MMP2 protein]

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

increases abundance

MTHFD1 protein results in increased abundance of S-Adenosylmethionine

NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372

G

5-methyltetrahydrofolate-homocysteine methyltransferase

affects binding
multiple interactions

S-Adenosylmethionine binds to MTR protein
[glutathionylcobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form; [Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form; Aluminum inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]; Arsenic inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]; Buthionine Sulfoximine inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]; Glutathione inhibits the reaction [Buthionine Sulfoximine inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]]; Glutathione inhibits the reaction [Thimerosal inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]]; Glutathione promotes the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]; Lead inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]; mecobalamin inhibits the reaction [Buthionine Sulfoximine inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]]; Mercury inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]; Thimerosal inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]

PMID:17477549 PMID:26989453

NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822

G

N-myc downstream regulated 1

decreases expression

S-Adenosylmethionine results in decreased expression of NDRG1 mRNA

NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880

G

NFE2 like bZIP transcription factor 2

multiple interactions

[S-Adenosylmethionine co-treated with Arsenic] results in increased expression of NFE2L2 mRNA; S-Adenosylmethionine inhibits the reaction [Lithocholic Acid results in decreased expression of NFE2L2 protein]; S-Adenosylmethionine promotes the reaction [Ursodeoxycholic Acid inhibits the reaction [Lithocholic Acid results in decreased expression of NFE2L2 protein]]

PMID:20146260 PMID:35490796

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NFKB inhibitor alpha

multiple interactions

S-Adenosylmethionine inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein]

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

neuroligin 3

multiple interactions

S-Adenosylmethionine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NLGN3 mRNA]; S-Adenosylmethionine inhibits the reaction [Hydrogen Peroxide results in increased methylation of NLGN3 promoter]; S-Adenosylmethionine inhibits the reaction [Particulate Matter results in decreased expression of NLGN3 mRNA]; S-Adenosylmethionine inhibits the reaction [Particulate Matter results in decreased expression of NLGN3 protein]; S-Adenosylmethionine inhibits the reaction [Particulate Matter results in increased methylation of NLGN3 promoter]

NCBI chr X:66,427,926...66,457,378
Ensembl chr X:66,429,458...66,451,876

G

nuclear receptor subfamily 0, group B, member 2

increases abundance

NR0B2 protein results in increased abundance of S-Adenosylmethionine

NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609

G

neurexin 1

multiple interactions

S-Adenosylmethionine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NRXN1 mRNA]; S-Adenosylmethionine inhibits the reaction [Hydrogen Peroxide results in increased methylation of NRXN1 promoter]; S-Adenosylmethionine inhibits the reaction [Particulate Matter results in decreased expression of NRXN1 mRNA]; S-Adenosylmethionine inhibits the reaction [Particulate Matter results in decreased expression of NRXN1 protein]; S-Adenosylmethionine inhibits the reaction [Particulate Matter results in increased methylation of NRXN1 promoter]

NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710

G

poly (ADP-ribose) polymerase 1

multiple interactions

S-Adenosylmethionine inhibits the reaction [Arsenic results in decreased expression of PARP1 mRNA]

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

phosphodiesterase 4B

multiple interactions

[[S-Adenosylmethionine inhibits the reaction [Lipopolysaccharides results in increased expression of PDE4B mRNA]] which results in increased abundance of Cyclic AMP] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; [S-Adenosylmethionine inhibits the reaction [Lipopolysaccharides results in increased expression of PDE4B mRNA]] which results in increased abundance of Cyclic AMP; S-Adenosylmethionine inhibits the reaction [Lipopolysaccharides results in increased expression of PDE4B mRNA]

NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696

G

phosphatidylethanolamine N-methyltransferase

multiple interactions

PEMT protein promotes the reaction [AHR protein results in decreased abundance of S-Adenosylmethionine]

NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013

G

profilin 2

decreases expression

S-Adenosylmethionine results in decreased expression of PFN2 mRNA

NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938

G

proteasome 20S subunit beta 8

increases expression

S-Adenosylmethionine results in increased expression of PSMB8 mRNA

NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283

G

prostaglandin-endoperoxide synthase 1

decreases expression

S-Adenosylmethionine results in decreased expression of PTGS1 mRNA

NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586

G

prostaglandin-endoperoxide synthase 2

multiple interactions

[S-Adenosylmethionine co-treated with Arsenic] affects the expression of PTGS2 mRNA; [S-Adenosylmethionine inhibits the reaction [Arsenic results in decreased methylation of PTGS2 promoter]] which results in decreased expression of PTGS2 mRNA; S-Adenosylmethionine inhibits the reaction [Arsenic results in decreased methylation of PTGS2 promoter]

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

S-Adenosylmethionine inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

ribonuclease L

decreases expression

S-Adenosylmethionine results in decreased expression of RNASEL mRNA

NCBI chr13:65,894,990...65,910,354
Ensembl chr13:65,901,459...65,908,704

G

RT1 class II, locus Db1

decreases expression

S-Adenosylmethionine results in decreased expression of H2-EB1 mRNA

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

G

solute carrier family 19 member 1

affects abundance

SLC19A1 protein affects the abundance of S-Adenosylmethionine

NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972

G

SET and MYND domain containing 2

affects binding

S-Adenosylmethionine binds to SMYD2 protein

NCBI chr13:101,425,270...101,466,576
Ensembl chr13:101,425,273...101,466,576

G

suppressor of cytokine signaling 3

multiple interactions

[S-Adenosylmethionine co-treated with Arsenic] affects the expression of SOCS3 mRNA; [S-Adenosylmethionine inhibits the reaction [Arsenic results in decreased methylation of SOCS3 promoter]] which results in decreased expression of SOCS3 mRNA; S-Adenosylmethionine inhibits the reaction [Arsenic results in decreased methylation of SOCS3 promoter]

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

G

superoxide dismutase 1

multiple interactions

S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased activity of SOD1 protein]

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

multiple interactions

S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased activity of SOD2 protein]

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

Sp1 transcription factor

multiple interactions

S-Adenosylmethionine inhibits the reaction [TGFB1 protein promotes the reaction [SP1 protein binds to MAPK1 protein modified form]]; S-Adenosylmethionine inhibits the reaction [TGFB1 protein promotes the reaction [SP1 protein binds to MAPK3 protein modified form]]
S-Adenosylmethionine inhibits the reaction [SP1 protein binds to COL1A2 promoter]

NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961

G

synapsin I

multiple interactions

S-Adenosylmethionine inhibits the reaction [Particulate Matter results in decreased expression of SYN1 protein]

NCBI chr X:1,172,208...1,227,400
Ensembl chr X:1,172,208...1,227,396

G

transferrin

multiple interactions
increases expression

[S-Adenosylmethionine results in increased expression of TF protein] which affects the abundance of Iron

NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511

G

trefoil factor 1

multiple interactions

S-Adenosylmethionine inhibits the reaction [[arsenic trioxide results in increased expression of ESR1 protein] which results in increased expression of TFF1 mRNA]; S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in increased expression of TFF1 mRNA]

NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597

G

transferrin receptor

decreases expression

S-Adenosylmethionine results in decreased expression of TFRC mRNA

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

transforming growth factor, beta 1

multiple interactions

S-Adenosylmethionine inhibits the reaction [TGFB1 protein promotes the reaction [SP1 protein binds to MAPK1 protein modified form]]; S-Adenosylmethionine inhibits the reaction [TGFB1 protein promotes the reaction [SP1 protein binds to MAPK3 protein modified form]]
S-Adenosylmethionine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]; S-Adenosylmethionine inhibits the reaction [TGFB1 protein binds to COL1A2 promoter]; S-Adenosylmethionine inhibits the reaction [TGFB1 protein results in increased phosphorylation of MAPK1 protein]; S-Adenosylmethionine inhibits the reaction [TGFB1 protein results in increased phosphorylation of MAPK3 protein]

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

tumor necrosis factor

multiple interactions

[[S-Adenosylmethionine inhibits the reaction [Lipopolysaccharides results in increased expression of PDE4B mRNA]] which results in increased abundance of Cyclic AMP] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
S-Adenosylmethionine inhibits the reaction [Thioacetamide results in increased expression of TNF protein]

PMID:19822164 PMID:21266552

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

thiopurine S-methyltransferase

multiple interactions

[S-Adenosylmethionine analog co-treated with TPMT protein] results in increased methylation of 4-methylbenzenethiol; [S-Adenosylmethionine analog co-treated with TPMT protein] results in increased methylation of 4-nitrobenzenthiol; [S-Adenosylmethionine co-treated with TPMT protein] results in increased methylation of 4-methylbenzenethiol; [S-Adenosylmethionine co-treated with TPMT protein] results in increased methylation of 4-nitrobenzenthiol; S-Adenosylmethionine analog inhibits the reaction [[S-Adenosylmethionine co-treated with TPMT protein] results in increased methylation of 4-nitrobenzenthiol]; S-Adenosylmethionine inhibits the reaction [[S-Adenosylmethionine analog co-treated with TPMT protein] results in increased methylation of 4-nitrobenzenthiol]

NCBI chr17:17,644,088...17,662,709
Ensembl chr17:17,644,173...17,662,709

G

ubiquitin D

multiple interactions

S-Adenosylmethionine inhibits the reaction [Dicarbethoxydihydrocollidine results in increased expression of UBD mRNA]

NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639

G

vimentin

multiple interactions

S-Adenosylmethionine inhibits the reaction [monobutyl phthalate results in increased expression of VIM mRNA]; S-Adenosylmethionine inhibits the reaction [monobutyl phthalate results in increased expression of VIM protein]
S-Adenosylmethionine inhibits the reaction [sodium arsenite results in decreased expression of VIM protein]

PMID:26745512 PMID:37682722

NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187

G

X-ray repair cross complementing 1

multiple interactions

S-Adenosylmethionine inhibits the reaction [Arsenic results in decreased expression of XRCC1 mRNA]

NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19808
chemical entity	19806
molecular entity	19806
ion	16690
anion	16074
organic anion	3610
carboxylic acid anion	2475
amino-acid anion	832
6-aminohexanoate	7
7,8-diaminononanoate	0
N-(carboxylatoaminomethyl)urea	0
alpha-amino-acid anion +	822
amino fatty acid anion +	0
aromatic amino-acid anion +	0
beta-amino-acid anion +	0
branched-chain amino-acid anion +	0
carbamate +	0
cyanoamino acid anion +	0
gamma-amino acid anion +	2
glyco-amino-acid anion +	0
ketorolac(1-) +	12
methylcarbamate	0
sulfur-containing amino-acid anion +	93
xanthommatin(1-)	0
Path 2
Term	Annotations
CHEBI ontology	19808
subatomic particle	19806
composite particle	19806
hadron	19806
baryon	19806
nucleon	19806
atomic nucleus	19806
atom	19806
main group element atom	19756
p-block element atom	19756
carbon group element atom	19705
carbon atom	19702
organic molecular entity	19702
organic ion	9858
organic anion	3610
carboxylic acid anion	2475
amino-acid anion	832
6-aminohexanoate	7
7,8-diaminononanoate	0
N-(carboxylatoaminomethyl)urea	0
alpha-amino-acid anion +	822
amino fatty acid anion +	0
aromatic amino-acid anion +	0
beta-amino-acid anion +	0
branched-chain amino-acid anion +	0
carbamate +	0
cyanoamino acid anion +	0
gamma-amino acid anion +	2
glyco-amino-acid anion +	0
ketorolac(1-) +	12
methylcarbamate	0
sulfur-containing amino-acid anion +	93
xanthommatin(1-)	0

paths to the root