Recql (RecQ like helicase) - Rat Genome Database

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Pathways
Gene: Recql (RecQ like helicase) Rattus norvegicus
Analyze
Symbol: Recql
Name: RecQ like helicase
RGD ID: 1311071
Description: Predicted to enable nucleic acid conformation isomerase activity. Predicted to be involved in double-strand break repair via homologous recombination and replication fork processing. Predicted to be located in nucleoplasm. Predicted to be active in chromosome and cytoplasm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and pancreatic cancer. Orthologous to human RECQL (RecQ like helicase); INTERACTS WITH 2,6-dinitrotoluene; acrylamide; allethrin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP-dependent DNA helicase Q1; DNA 3'-5' helicase Q1; DNA-dependent ATPase Q1; LOC312824; RecQ helicase-like; RecQ protein-like; RecQ protein-like (DNA helicase Q1-like); recQ protein-like 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84177,039,351 - 177,063,968 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4177,035,128 - 177,063,838 (-)EnsemblGRCr8
mRatBN7.24175,308,337 - 175,332,965 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4175,304,117 - 175,332,945 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4181,603,185 - 181,627,672 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04177,387,454 - 177,411,941 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04176,008,012 - 176,032,500 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04176,581,892 - 176,606,520 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4176,581,897 - 176,606,382 (-)Ensemblrn6Rnor6.0
Rnor_5.04240,795,675 - 240,820,290 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44179,927,255 - 179,951,742 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4163,841,046 - 163,865,533 (-)NCBICelera
RGSC_v3.14180,172,380 - 180,196,866 (-)NCBI
Cytogenetic Map4q44NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,6-dinitrotoluene  (EXP)
2-bromohexadecanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
allethrin  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
clofibric acid  (EXP)
cocaine  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (EXP)
cypermethrin  (EXP)
dibenz[a,h]anthracene  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
FR900359  (ISO)
glafenine  (EXP)
ivermectin  (ISO)
ketamine  (EXP)
kojic acid  (ISO)
levonorgestrel  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monosodium L-glutamate  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
paracetamol  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
piroxicam  (ISO)
propanal  (ISO)
pyrethrins  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
Testosterone propionate  (ISO)
testosterone undecanoate  (ISO)
thapsigargin  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromosome  (IBA)
cytoplasm  (IBA)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Single nucleotide polymorphism in RECQL and survival in resectable pancreatic adenocarcinoma. Cotton RT, etal., HPB (Oxford). 2009;11(5):435-44.
2. Anticancer activity of RecQL1 helicase siRNA in mouse xenograft models. Futami K, etal., Cancer Sci. 2008 Jun;99(6):1227-36. Epub 2008 Apr 14.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival. Li D, etal., Cancer Res. 2006 Mar 15;66(6):3323-30.
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11562355   PMID:12477932   PMID:15489334   PMID:19177149   PMID:19946888  


Genomics

Comparative Map Data
Recql
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84177,039,351 - 177,063,968 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4177,035,128 - 177,063,838 (-)EnsemblGRCr8
mRatBN7.24175,308,337 - 175,332,965 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4175,304,117 - 175,332,945 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4181,603,185 - 181,627,672 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04177,387,454 - 177,411,941 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04176,008,012 - 176,032,500 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04176,581,892 - 176,606,520 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4176,581,897 - 176,606,382 (-)Ensemblrn6Rnor6.0
Rnor_5.04240,795,675 - 240,820,290 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44179,927,255 - 179,951,742 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4163,841,046 - 163,865,533 (-)NCBICelera
RGSC_v3.14180,172,380 - 180,196,866 (-)NCBI
Cytogenetic Map4q44NCBI
RECQL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381221,468,910 - 21,501,635 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1221,468,910 - 21,501,669 (-)Ensemblhg38GRCh38
GRCh371221,621,844 - 21,654,569 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361221,513,965 - 21,545,796 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341221,514,353 - 21,545,796NCBI
Celera1226,777,229 - 26,809,985 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1221,395,874 - 21,428,641 (-)NCBIHuRef
CHM1_11221,587,472 - 21,620,203 (-)NCBICHM1_1
T2T-CHM13v2.01221,347,594 - 21,380,648 (-)NCBIT2T-CHM13v2.0
Recql
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396142,296,068 - 142,332,802 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6142,296,068 - 142,332,813 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386142,350,342 - 142,387,100 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6142,350,342 - 142,387,087 (-)Ensemblmm10GRCm38
MGSCv376142,310,420 - 142,335,607 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366142,319,368 - 142,344,253 (-)NCBIMGSCv36mm8
Celera6145,421,861 - 145,447,035 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map673.91NCBI
Recql
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541317,113,408 - 17,148,708 (-)Ensembl
ChiLan1.0NW_00495541317,115,443 - 17,148,708 (-)NCBIChiLan1.0ChiLan1.0
RECQL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21075,300,616 - 75,333,274 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11275,297,014 - 75,329,247 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01264,796,383 - 64,829,165 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11267,400,315 - 67,432,724 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1267,400,315 - 67,432,724 (+)EnsemblpanPan2panpan1.1
RECQL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12725,590,326 - 25,636,304 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2725,590,831 - 25,636,685 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2720,715,583 - 20,761,524 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02725,818,962 - 25,865,150 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2725,819,030 - 25,865,148 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12725,611,850 - 25,658,034 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02725,634,863 - 25,681,036 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02720,891,461 - 20,937,671 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Recql
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494587,426,992 - 87,463,355 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365485,362,517 - 5,384,338 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365485,349,878 - 5,384,603 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RECQL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl551,953,451 - 52,003,740 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1551,953,460 - 51,995,619 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2555,229,615 - 55,272,155 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RECQL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11121,334,601 - 21,366,943 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1121,331,584 - 21,366,979 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606913,777,790 - 13,810,627 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Recql
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475217,185,129 - 17,220,707 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475217,183,624 - 17,220,954 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Recql
150 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:71
Interacting mature miRNAs:77
Transcripts:ENSRNOT00000065576
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4176806581181925369Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4160623982184426481Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat

Markers in Region
RH130945  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24175,308,472 - 175,308,664 (+)MAPPERmRatBN7.2
Rnor_6.04176,582,028 - 176,582,219NCBIRnor6.0
Rnor_5.04240,795,811 - 240,796,002UniSTSRnor5.0
RGSC_v3.44179,927,388 - 179,927,579UniSTSRGSC3.4
Celera4163,841,179 - 163,841,370UniSTS
RH 3.4 Map41031.2UniSTS
Cytogenetic Map4q44UniSTS
BI295118  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24175,317,447 - 175,317,546 (+)MAPPERmRatBN7.2
Rnor_6.04176,591,002 - 176,591,100NCBIRnor6.0
Rnor_5.04240,804,785 - 240,804,883UniSTSRnor5.0
RGSC_v3.44179,936,362 - 179,936,460UniSTSRGSC3.4
Celera4163,850,153 - 163,850,251UniSTS
RH 3.4 Map41044.7UniSTS
Cytogenetic Map4q44UniSTS
RH141072  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr84177,041,792 - 177,041,982 (+)Marker Load Pipeline
mRatBN7.24175,310,780 - 175,310,971 (+)MAPPERmRatBN7.2
Rnor_6.04176,584,336 - 176,584,526NCBIRnor6.0
Rnor_5.04240,798,119 - 240,798,309UniSTSRnor5.0
RGSC_v3.44179,929,696 - 179,929,886UniSTSRGSC3.4
Celera4163,843,487 - 163,843,677UniSTS
RH 3.4 Map41032.2UniSTS
Cytogenetic Map4q44UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC134270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC079026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000065576   ⟹   ENSRNOP00000060671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4177,038,503 - 177,063,838 (-)Ensembl
mRatBN7.2 Ensembl4175,308,342 - 175,332,828 (-)Ensembl
Rnor_6.0 Ensembl4176,581,897 - 176,606,382 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086365   ⟹   ENSRNOP00000073537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4175,309,759 - 175,322,961 (-)Ensembl
Rnor_6.0 Ensembl4176,582,006 - 176,596,591 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110058   ⟹   ENSRNOP00000077921
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4177,038,942 - 177,063,838 (-)Ensembl
mRatBN7.2 Ensembl4175,308,344 - 175,332,945 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114762   ⟹   ENSRNOP00000085782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4177,035,128 - 177,063,838 (-)Ensembl
mRatBN7.2 Ensembl4175,304,117 - 175,332,917 (-)Ensembl
RefSeq Acc Id: NM_001012098   ⟹   NP_001012098
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,838 (-)NCBI
mRatBN7.24175,308,340 - 175,332,828 (-)NCBI
Rnor_6.04176,581,895 - 176,606,382 (-)NCBI
Rnor_5.04240,795,675 - 240,820,290 (-)NCBI
RGSC_v3.44179,927,255 - 179,951,742 (-)RGD
Celera4163,841,046 - 163,865,533 (-)RGD
Sequence:
RefSeq Acc Id: XM_006237617   ⟹   XP_006237679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
mRatBN7.24175,308,337 - 175,332,965 (-)NCBI
Rnor_6.04176,581,892 - 176,606,515 (-)NCBI
Rnor_5.04240,795,675 - 240,820,290 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237618   ⟹   XP_006237680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,891 (-)NCBI
mRatBN7.24175,308,337 - 175,332,867 (-)NCBI
Rnor_6.04176,581,892 - 176,606,421 (-)NCBI
Rnor_5.04240,795,675 - 240,820,290 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237619   ⟹   XP_006237681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
mRatBN7.24175,308,337 - 175,332,960 (-)NCBI
Rnor_6.04176,581,892 - 176,606,520 (-)NCBI
Rnor_5.04240,795,675 - 240,820,290 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237620   ⟹   XP_006237682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,883 (-)NCBI
mRatBN7.24175,308,337 - 175,332,858 (-)NCBI
Rnor_6.04176,581,892 - 176,606,420 (-)NCBI
Rnor_5.04240,795,675 - 240,820,290 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039107700   ⟹   XP_038963628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,877 (-)NCBI
mRatBN7.24175,308,337 - 175,332,867 (-)NCBI
RefSeq Acc Id: XM_039107701   ⟹   XP_038963629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,891 (-)NCBI
mRatBN7.24175,308,337 - 175,332,867 (-)NCBI
RefSeq Acc Id: XM_039107702   ⟹   XP_038963630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
mRatBN7.24175,308,639 - 175,332,960 (-)NCBI
RefSeq Acc Id: XM_039107703   ⟹   XP_038963631
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,891 (-)NCBI
mRatBN7.24175,308,337 - 175,332,867 (-)NCBI
RefSeq Acc Id: XM_063286165   ⟹   XP_063142235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,958 (-)NCBI
RefSeq Acc Id: XM_063286166   ⟹   XP_063142236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
RefSeq Acc Id: XM_063286167   ⟹   XP_063142237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
RefSeq Acc Id: XM_063286169   ⟹   XP_063142239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,875 (-)NCBI
RefSeq Acc Id: XM_063286170   ⟹   XP_063142240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,957 (-)NCBI
RefSeq Acc Id: XM_063286171   ⟹   XP_063142241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
RefSeq Acc Id: XM_063286172   ⟹   XP_063142242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,873 (-)NCBI
RefSeq Acc Id: NP_001012098   ⟸   NM_001012098
- UniProtKB: Q6AYJ1 (UniProtKB/Swiss-Prot),   A6IMT6 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237681   ⟸   XM_006237619
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y8C0 (UniProtKB/TrEMBL),   A6IMT7 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237679   ⟸   XM_006237617
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y8C0 (UniProtKB/TrEMBL),   A6IMT7 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237680   ⟸   XM_006237618
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y8C0 (UniProtKB/TrEMBL),   A6IMT7 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237682   ⟸   XM_006237620
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y8C0 (UniProtKB/TrEMBL),   A6IMT7 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000060671   ⟸   ENSRNOT00000065576
Ensembl Acc Id: ENSRNOP00000073537   ⟸   ENSRNOT00000086365
RefSeq Acc Id: XP_038963628   ⟸   XM_039107700
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963631   ⟸   XM_039107703
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963629   ⟸   XM_039107701
- Peptide Label: isoform X3
- UniProtKB: Q6AYJ1 (UniProtKB/Swiss-Prot),   A6IMT6 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963630   ⟸   XM_039107702
- Peptide Label: isoform X3
- UniProtKB: Q6AYJ1 (UniProtKB/Swiss-Prot),   A6IMT6 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085782   ⟸   ENSRNOT00000114762
Ensembl Acc Id: ENSRNOP00000077921   ⟸   ENSRNOT00000110058
RefSeq Acc Id: XP_063142236   ⟸   XM_063286166
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142241   ⟸   XM_063286171
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142237   ⟸   XM_063286167
- Peptide Label: isoform X3
- UniProtKB: Q6AYJ1 (UniProtKB/Swiss-Prot),   A6IMT6 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142235   ⟸   XM_063286165
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142240   ⟸   XM_063286170
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142239   ⟸   XM_063286169
- Peptide Label: isoform X3
- UniProtKB: Q6AYJ1 (UniProtKB/Swiss-Prot),   A6IMT6 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142242   ⟸   XM_063286172
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A2E6 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYJ1-F1-model_v2 AlphaFold Q6AYJ1 1-621 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693486
Promoter ID:EPDNEW_R4010
Type:initiation region
Name:Recql_1
Description:RecQ like helicase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04176,606,447 - 176,606,507EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311071 AgrOrtholog
BioCyc Gene G2FUF-42495 BioCyc
Ensembl Genes ENSRNOG00000012602 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000065576 ENTREZGENE
  ENSRNOT00000065576.3 UniProtKB/Swiss-Prot
  ENSRNOT00000110058 ENTREZGENE
  ENSRNOT00000114762 ENTREZGENE
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7114009 IMAGE-MGC_LOAD
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/Swiss-Prot
  DNA_helicase_ATP-dep_RecQ UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  RecQ_Zn-bd UniProtKB/Swiss-Prot
  RQC_domain UniProtKB/Swiss-Prot
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot
KEGG Report rno:312824 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93953 IMAGE-MGC_LOAD
NCBI Gene 312824 ENTREZGENE
PANTHER ATP-DEPENDENT DNA HELICASE Q1 UniProtKB/Swiss-Prot
  DNA HELICASE RECQ FAMILY MEMBER UniProtKB/Swiss-Prot
Pfam DEAD UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  RecQ_Zn_bind UniProtKB/Swiss-Prot
  RQC UniProtKB/Swiss-Prot
PhenoGen Recql PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012602 RatGTEx
SMART DEXDc UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A0G2K5S2_RAT UniProtKB/TrEMBL
  A0A8I5Y8C0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2E6 ENTREZGENE, UniProtKB/TrEMBL
  A6IMT6 ENTREZGENE, UniProtKB/TrEMBL
  A6IMT7 ENTREZGENE, UniProtKB/TrEMBL
  Q6AYJ1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Recql  RecQ like helicase  Recql  RecQ helicase-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-03-13 Recql  RecQ helicase-like  Recql  RecQ protein-like (DNA helicase Q1-like)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-24 Recql  RecQ protein-like (DNA helicase Q1-like)  Recql  RecQ protein-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Recql  RecQ protein-like  Recql_predicted  RecQ protein-like (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Recql_predicted  RecQ protein-like (predicted)      Symbol and Name status set to approved 70820 APPROVED