Gene: Erlin1 (ER lipid raft associated 1) Rattus norvegicus
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Symbol: Erlin1
Name: ER lipid raft associated 1
Description: ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN negative regulation of cholesterol biosynthetic process (ortholog); negative regulation of fatty acid biosynthetic process (ortholog); SREBP signaling pathway (ortholog); ASSOCIATED WITH hereditary spastic paraplegia 62 (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; diuron
AGR Description: Predicted to have cholesterol binding activity; predicted to be involved in SREBP signaling pathway, negative regulation of biosynthetic process, and ubiquitin-dependent ERAD pathway; predicted to localize to the endoplasmic reticulum membrane and protein-containing complex; orthologous to human ERLIN1 (ER lipid raft associated 1).
Merged Description: Predicted to have cholesterol binding activity; predicted to be involved in SREBP signaling pathway, negative regulation of biosynthetic process, and ubiquitin-dependent ERAD pathway; predicted to localize to the endoplasmic reticulum membrane and protein-containing complex; orthologous to human ERLIN1 (ER lipid raft associated 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; diuron.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: erlin-1; LOC293939; RGD1307058; similar to band 7 protein (35.3 kD) (4N53); SPFH domain family, member 1; Spfh1
Orthologs:
Homo sapiens (human) : ERLIN1 (ER lipid raft associated 1)  HGNC  Alliance
Mus musculus (house mouse) : Erlin1 (ER lipid raft associated 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Erlin1 (ER lipid raft associated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ERLIN1 (ER lipid raft associated 1)
Canis lupus familiaris (dog) : ERLIN1 (ER lipid raft associated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Erlin1 (ER lipid raft associated 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01263,810,439 - 263,845,762 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01271,255,433 - 271,290,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41249,161,437 - 249,196,760 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11249,420,178 - 249,453,615 (+)NCBI
Celera1238,738,636 - 238,773,959 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Erlin1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307058
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.