ERLIN1 (ER lipid raft associated 1) - Rat Genome Database

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Gene: ERLIN1 (ER lipid raft associated 1) Chlorocebus sabaeus
Analyze
Symbol: ERLIN1
Name: ER lipid raft associated 1
RGD ID: 18456339
Description: ENCODES a protein that exhibits cholesterol binding (inferred); lipid binding (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN cholesterol metabolic process (inferred); ERAD pathway (inferred); negative regulation of cholesterol biosynthetic process (inferred); ASSOCIATED WITH COVID-19 (ortholog); hereditary spastic paraplegia (ortholog); hereditary spastic paraplegia 62 (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: erlin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1993,181,320 - 93,217,967 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl993,181,319 - 93,217,034 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604854,182,581 - 54,218,350 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ERLIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1993,181,320 - 93,217,967 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl993,181,319 - 93,217,034 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604854,182,581 - 54,218,350 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ERLIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810100,150,094 - 100,186,029 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10100,150,094 - 100,186,033 (-)EnsemblGRCh38hg38GRCh38
GRCh3710101,909,851 - 101,945,786 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610101,899,837 - 101,935,804 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410101,899,841 - 101,935,393NCBI
Celera1095,647,790 - 95,683,757 (-)NCBICelera
Cytogenetic Map10q24.31NCBI
HuRef1095,538,784 - 95,574,746 (-)NCBIHuRef
CHM1_110102,194,537 - 102,230,501 (-)NCBICHM1_1
T2T-CHM13v2.010101,034,336 - 101,070,271 (-)NCBIT2T-CHM13v2.0
Erlin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391944,023,382 - 44,058,580 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1944,023,383 - 44,058,224 (-)EnsemblGRCm39 Ensembl
GRCm381944,034,943 - 44,070,164 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1944,034,944 - 44,069,785 (-)EnsemblGRCm38mm10GRCm38
MGSCv371944,109,433 - 44,144,275 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361944,088,258 - 44,122,836 (-)NCBIMGSCv36mm8
Celera1944,820,444 - 44,855,267 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1936.7NCBI
Erlin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81252,870,356 - 252,905,681 (-)NCBIGRCr8
mRatBN7.21242,921,147 - 242,956,472 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,921,152 - 242,956,394 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1251,071,489 - 251,106,785 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01257,768,244 - 257,803,553 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01250,421,641 - 250,456,935 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01263,810,439 - 263,845,762 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1263,810,439 - 263,845,762 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01271,255,433 - 271,290,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41249,161,437 - 249,196,760 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11249,420,178 - 249,453,615 (+)NCBI
Celera1238,738,636 - 238,773,959 (-)NCBICelera
Cytogenetic Map1q54NCBI
Erlin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555076,028,324 - 6,063,689 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555076,029,247 - 6,062,946 (-)NCBIChiLan1.0ChiLan1.0
ERLIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28112,039,719 - 112,075,365 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110112,045,038 - 112,080,263 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01096,756,261 - 96,791,925 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110100,238,320 - 100,273,971 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10100,238,320 - 100,273,942 (-)Ensemblpanpan1.1panPan2
ERLIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12812,924,942 - 12,962,016 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2812,927,018 - 12,961,983 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2813,108,086 - 13,145,157 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02813,393,298 - 13,430,578 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2813,393,304 - 13,430,564 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12812,940,139 - 12,977,413 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02812,978,226 - 13,015,269 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02813,112,507 - 13,149,560 (-)NCBIUU_Cfam_GSD_1.0
Erlin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721334,041,433 - 34,076,926 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493663680,564 - 116,694 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493663680,583 - 116,027 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
Erlin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473711,977,397 - 12,018,438 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473711,977,397 - 12,018,437 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000003700   ⟹   ENSCSAP00000001977
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl993,181,319 - 93,217,034 (-)Ensembl
RefSeq Acc Id: XM_007963827   ⟹   XP_007962018
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1993,181,320 - 93,217,962 (-)NCBI
Vero_WHO_p1.0NW_02366604854,182,581 - 54,218,350 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007963829   ⟹   XP_007962020
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1993,181,320 - 93,216,955 (-)NCBI
Vero_WHO_p1.0NW_02366604854,182,581 - 54,218,288 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038009437   ⟹   XP_037865365
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604854,182,581 - 54,218,293 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007962018 (Get FASTA)   NCBI Sequence Viewer  
  XP_007962020 (Get FASTA)   NCBI Sequence Viewer  
  XP_037865365 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001977
  ENSCSAP00000001977.1
RefSeq Acc Id: XP_007962018   ⟸   XM_007963827
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R038 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007962020   ⟸   XM_007963829
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R038 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000001977   ⟸   ENSCSAT00000003700
RefSeq Acc Id: XP_037865365   ⟸   XM_038009437
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005667 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003700.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.479.30 UniProtKB/TrEMBL
InterPro Band_7 UniProtKB/TrEMBL
  Band_7/SPFH_dom_sf UniProtKB/TrEMBL
  Erlin1/2 UniProtKB/TrEMBL
NCBI Gene ERLIN1 ENTREZGENE
PANTHER ERLIN-1 UniProtKB/TrEMBL
  PTHR15351 UniProtKB/TrEMBL
Pfam Band_7 UniProtKB/TrEMBL
SMART PHB UniProtKB/TrEMBL
Superfamily-SCOP SSF117892 UniProtKB/TrEMBL
UniProt A0A0D9R038 ENTREZGENE, UniProtKB/TrEMBL