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Gene: Erlin1 (ER lipid raft associated 1) Mus musculus
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Symbol: Erlin1
Name: ER lipid raft associated 1
Description: Predicted to have cholesterol binding activity. Predicted to be involved in SREBP signaling pathway; negative regulation of lipid biosynthetic process; and ubiquitin-dependent ERAD pathway. Predicted to localize to the endoplasmic reticulum; endoplasmic reticulum membrane; and protein-containing complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 62. Orthologous to human ERLIN1 (ER lipid raft associated 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810439N09Rik; C80197; endoplasmic reticulum lipid raft-associated protein 1; erlin-1; Keo4; protein KE04 homolog; SPFH domain family, member 1; SPFH domain-containing protein 1; Spfh1; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
Orthologs:
Homo sapiens (human) : ERLIN1 (ER lipid raft associated 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Erlin1 (ER lipid raft associated 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Erlin1 (ER lipid raft associated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ERLIN1 (ER lipid raft associated 1)
Canis lupus familiaris (dog) : ERLIN1 (ER lipid raft associated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Erlin1 (ER lipid raft associated 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1944,034,944 - 44,069,785 (-)Ensembl
GRCm381944,034,943 - 44,070,164 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371944,109,433 - 44,144,275 (-)NCBIGRCm37mm9NCBIm37
MGSCv361944,088,258 - 44,122,836 (-)NCBImm8
Celera1944,820,444 - 44,855,267 (-)NCBICelera
Cytogenetic Map19 C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Erlin1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551377
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.