Nipal1 (NIPA-like domain containing 1)

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Gene: Nipal1 (NIPA-like domain containing 1) Rattus norvegicus

Analyze

Symbol:

Nipal1

Name:

NIPA-like domain containing 1

RGD ID:

1310092

Description:

Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in magnesium ion transport. Predicted to be located in Golgi apparatus. Predicted to be active in membrane. Orthologous to human NIPAL1 (NIPA like domain containing 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC289594; magnesium transporter NIPA3; Npal1; RGD1310092; similar to NIPA2

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NIPAL1 (NIPA like domain containing 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Nipal1 (NIPA-like domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nipal1 (NIPA like domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NIPAL1 (NIPA like domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NIPAL1 (NIPA like domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nipal1 (NIPA like domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NIPAL1 (NIPA like domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NIPAL1 (NIPA like domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nipal1 (NIPA like domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	HSD11B1 (hydroxysteroid 11-beta dehydrogenase 1)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Nipal1 (NIPA-like domain containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	NIPAL1 (NIPA like domain containing 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nipa-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	spict	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nipal1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	35,537,641 - 35,561,656 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	35,540,324 - 35,561,659 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	35,903,133 - 35,927,070 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	37,207,879 - 37,231,816 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	35,696,250 - 35,720,191 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	38,104,027 - 38,128,038 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	38,104,047 - 38,128,024 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	37,914,565 - 37,938,564 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	37,965,997 - 37,990,014 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	37,969,451 - 37,993,302 (-)	NCBI
Celera	14	34,793,332 - 34,814,626 (-)	NCBI		Celera
Cytogenetic Map	14	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

acetamide (EXP)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (ISO)

cisplatin (ISO)

cobalt atom (ISO)

dichloroacetic acid (ISO)

diclofenac (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

flutamide (EXP)

gentamycin (EXP)

inulin (ISO)

iron dichloride (ISO)

methamphetamine (ISO)

monosodium L-glutamate (ISO)

N-nitrosodiethylamine (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

parathion (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

rac-lactic acid (ISO)

SB 431542 (ISO)

tetrachloroethene (ISO)

tetrachloromethane (ISO)

thapsigargin (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

Triptolide (ISO)

tunicamycin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

magnesium ion transmembrane transport (IEA)

magnesium ion transport (IBA,ISO)

Cellular Component

Golgi apparatus (ISO)

membrane (IBA)

Molecular Function

magnesium ion transmembrane transporter activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:18667602

Genomics

Comparative Map Data

Nipal1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	35,537,641 - 35,561,656 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	35,540,324 - 35,561,659 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	35,903,133 - 35,927,070 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	37,207,879 - 37,231,816 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	35,696,250 - 35,720,191 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	38,104,027 - 38,128,038 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	38,104,047 - 38,128,024 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	37,914,565 - 37,938,564 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	37,965,997 - 37,990,014 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	37,969,451 - 37,993,302 (-)	NCBI
Celera	14	34,793,332 - 34,814,626 (-)	NCBI		Celera
Cytogenetic Map	14	p11	NCBI

NIPAL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	48,016,772 - 48,040,173 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	47,914,142 - 48,040,173 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	48,018,789 - 48,042,190 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	47,713,548 - 47,733,841 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	4	48,467,642 - 48,487,933 (+)	NCBI		Celera
Cytogenetic Map	4	p12	NCBI
HuRef	4	47,339,019 - 47,359,298 (+)	NCBI		HuRef
CHM1_1	4	48,017,882 - 48,038,161 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	47,983,845 - 48,007,239 (+)	NCBI		T2T-CHM13v2.0

Nipal1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	72,805,139 - 72,828,421 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	72,805,138 - 72,828,421 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	72,647,796 - 72,671,078 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	72,647,795 - 72,671,078 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	73,039,035 - 73,062,317 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	72,926,931 - 72,950,213 (+)	NCBI		MGSCv36	mm8
Celera	5	69,896,584 - 69,919,867 (+)	NCBI		Celera
Cytogenetic Map	5	C3.2	NCBI
cM Map	5	38.44	NCBI

Nipal1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955443	584,451 - 609,324 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955443	584,451 - 608,451 (-)	NCBI	ChiLan1.0	ChiLan1.0

NIPAL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	4	80,077,796 - 80,103,368 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	74,106,699 - 74,130,102 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	84,838,778 - 84,862,172 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	84,838,778 - 84,862,170 (-)	Ensembl	panpan1.1		panPan2

NIPAL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	43,877,377 - 43,900,871 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	43,877,393 - 43,897,671 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	43,829,924 - 43,853,246 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	44,477,241 - 44,500,597 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	44,477,205 - 44,499,733 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	44,154,655 - 44,177,990 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	43,686,663 - 43,709,959 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	44,569,803 - 44,593,134 (+)	NCBI		UU_Cfam_GSD_1.0

Nipal1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	32,130,309 - 32,150,720 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936482	14,147,667 - 14,169,074 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936482	14,147,716 - 14,168,758 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NIPAL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	37,936,847 - 37,962,908 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	37,936,812 - 37,963,492 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

NIPAL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	27	2,211,034 - 2,231,648 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	27	2,211,562 - 2,231,617 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	48,224,804 - 48,246,768 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nipal1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624761	18,923,369 - 18,949,324 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624761	18,923,352 - 18,949,288 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Nipal1
147 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	38
Count of miRNA genes:	35
Interacting mature miRNAs:	38
Transcripts:	ENSRNOT00000034642
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41131407	Rat
1581500	Renag1	Renal agenesis QTL 1			kidney development trait (VT:0000527)	percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)	14	8170668	68298175	Rat
1358296	Ael3	Aortic elastin QTL 3	3.7	0.00051	aorta elastin amount (VT:0003905)	aortic elastin	14	8267090	53267090	Rat
2302045	Pia39	Pristane induced arthritis QTL 39	4.9	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G2a level (CMO:0002116)	14	8267090	53267090	Rat
731183	Pia20	Pristane induced arthritis QTL 20	3.55		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	9088978	39057237	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11030622	95876975	Rat
71117	Niddm17	Non-insulin dependent diabetes mellitus QTL 17	2.35		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	17593761	42336881	Rat
631262	Tcas4	Tongue tumor susceptibility QTL 4	7.29		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	14	17622561	42337007	Rat
2313397	Coatc1	Coat color QTL1			coat/hair pigmentation trait (VT:0010463)	coat/hair color measurement (CMO:0001808)	14	18541332	63541332	Rat
61420	Pia6	Pristane induced arthritis QTL 6	4.9		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	14	18631345	42337007	Rat
10755459	Coatc15	Coat color QTL 15		0.01681	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	14	19836944	64836944	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30320092	80829842	Rat
2324617	Coatc2	Coat color QTL 2		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	14	30767025	39153750	Rat
1300154	Bp189	Blood pressure QTL 189	3.04		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	14	30883777	68757901	Rat

Markers in Region

RH142374

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	35,516,296 - 35,516,460 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	38,082,671 - 38,082,834	NCBI	Rnor6.0
Rnor_5.0	14	37,892,966 - 37,893,129	UniSTS	Rnor5.0
RGSC_v3.4	14	37,919,924 - 37,920,087	UniSTS	RGSC3.4
RGSC_v3.4	14	37,972,923 - 37,973,086	UniSTS	RGSC3.4
Celera	14	34,770,158 - 34,770,321	UniSTS
Cytogenetic Map	14	p11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2		32	32	6	32				17	1	1
Low	1		25	9	13	9	2	2		18	28	10	2
Below cutoff		41					6	8	61		12		6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001401452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC111383	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ235134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000034642 ⟹ ENSRNOP00000031068

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	35,540,324 - 35,561,640 (-)	Ensembl
Rnor_6.0 Ensembl	14	38,106,712 - 38,128,024 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000090303 ⟹ ENSRNOP00000073165

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	14	38,104,047 - 38,128,015 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000103689 ⟹ ENSRNOP00000081827

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	35,540,324 - 35,561,659 (-)	Ensembl

RefSeq Acc Id:

NM_001401452 ⟹ NP_001388381

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	35,537,641 - 35,561,656 (-)	NCBI

RefSeq Acc Id:

XM_039091702 ⟹ XP_038947630

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	35,537,641 - 35,543,288 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001388381	(Get FASTA)	NCBI Sequence Viewer
	XP_038947630	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL89988	(Get FASTA)	NCBI Sequence Viewer
	EDL89989	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000031068.4
	ENSRNOP00000081827
	ENSRNOP00000081827.1

RefSeq Acc Id:

ENSRNOP00000073165 ⟸ ENSRNOT00000090303

RefSeq Acc Id:

ENSRNOP00000031068 ⟸ ENSRNOT00000034642

RefSeq Acc Id:	XP_038947630 ⟸ XM_039091702
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSRNOP00000081827 ⟸ ENSRNOT00000103689

RefSeq Acc Id:	NP_001388381 ⟸ NM_001401452
- UniProtKB:	A0A0G2K4T6 (UniProtKB/TrEMBL), A6JD67 (UniProtKB/TrEMBL), A6JD66 (UniProtKB/TrEMBL), D3Z8L4 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K4T6-F1-model_v2	AlphaFold	A0A0G2K4T6	1-416	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699301

Promoter ID:

EPDNEW_R9824

Type:

initiation region

Name:

Nipal1_1

Description:

NIPA-like domain containing 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	38,128,000 - 38,128,060	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310092	AgrOrtholog
BioCyc Gene	G2FUF-15852	BioCyc
Ensembl Genes	ENSRNOG00000025882	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000034642.5	UniProtKB/TrEMBL
	ENSRNOT00000103689	ENTREZGENE
	ENSRNOT00000103689.1	UniProtKB/TrEMBL
InterPro	DUF803	UniProtKB/TrEMBL
KEGG Report	rno:289594	UniProtKB/TrEMBL
NCBI Gene	289594	ENTREZGENE
PANTHER	DUF803	UniProtKB/TrEMBL
	MAGNESIUM TRANSPORTER NIPA3	UniProtKB/TrEMBL
Pfam	DUF803	UniProtKB/TrEMBL
PhenoGen	Nipal1	PhenoGen
RatGTEx	ENSRNOG00000025882	RatGTEx
Superfamily-SCOP	Multidrug resistance efflux transporter EmrE	UniProtKB/TrEMBL
UniProt	A0A0G2K4T6	ENTREZGENE, UniProtKB/TrEMBL
	A6JD66	ENTREZGENE, UniProtKB/TrEMBL
	A6JD67	ENTREZGENE, UniProtKB/TrEMBL
	D3Z8L4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-04-23	Nipal1	NIPA-like domain containing 1	Npal1	NIPA-like domain containing 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Npal1	NIPA-like domain containing 1	Npal1_predicted	NIPA-like domain containing 1 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Npal1_predicted	NIPA-like domain containing 1 (predicted)	RGD1310092_predicted	similar to NIPA2 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1310092_predicted	similar to NIPA2 (predicted)	LOC289594_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC289594_predicted	similar to NIPA2 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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