Nipal1 (NIPA-like domain containing 1) - Rat Genome Database

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Gene: Nipal1 (NIPA-like domain containing 1) Mus musculus
Analyze
Symbol: Nipal1
Name: NIPA-like domain containing 1
RGD ID: 1320799
MGI Page MGI
Description: Predicted to enable magnesium ion transmembrane transporter activity. Involved in magnesium ion transport. Predicted to be integral component of membrane. Predicted to be active in membrane. Orthologous to human NIPAL1 (NIPA like domain containing 1); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3830408G10Rik; magnesium transporter NIPA3; N; NIPA-like protein 1; non-imprinted in Prader-Willi/Angelman syndrome region protein 3 homolog; Npal1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39572,805,139 - 72,828,421 (+)NCBIGRCm39mm39
GRCm39 Ensembl572,805,138 - 72,828,421 (+)Ensembl
GRCm38572,647,796 - 72,671,078 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl572,647,795 - 72,671,078 (+)EnsemblGRCm38mm10GRCm38
MGSCv37573,039,035 - 73,062,317 (+)NCBIGRCm37mm9NCBIm37
MGSCv36572,926,931 - 72,950,213 (+)NCBImm8
Celera569,896,584 - 69,919,867 (+)NCBICelera
Cytogenetic Map5C3.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:18667602   PMID:21267068   PMID:21873635   PMID:32439805  


Genomics

Comparative Map Data
Nipal1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39572,805,139 - 72,828,421 (+)NCBIGRCm39mm39
GRCm39 Ensembl572,805,138 - 72,828,421 (+)Ensembl
GRCm38572,647,796 - 72,671,078 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl572,647,795 - 72,671,078 (+)EnsemblGRCm38mm10GRCm38
MGSCv37573,039,035 - 73,062,317 (+)NCBIGRCm37mm9NCBIm37
MGSCv36572,926,931 - 72,950,213 (+)NCBImm8
Celera569,896,584 - 69,919,867 (+)NCBICelera
Cytogenetic Map5C3.2NCBI
NIPAL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl447,914,142 - 48,040,173 (+)EnsemblGRCh38hg38GRCh38
GRCh38448,016,772 - 48,040,173 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37448,018,789 - 48,042,190 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36447,713,548 - 47,733,841 (+)NCBINCBI36hg18NCBI36
Celera448,467,642 - 48,487,933 (+)NCBI
Cytogenetic Map4p12NCBI
HuRef447,339,019 - 47,359,298 (+)NCBIHuRef
CHM1_1448,017,882 - 48,038,161 (+)NCBICHM1_1
Nipal1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21435,537,641 - 35,561,651 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1435,540,324 - 35,561,659 (-)Ensembl
Rnor_6.01438,104,027 - 38,128,038 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1438,104,047 - 38,128,024 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01437,914,565 - 37,938,564 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41437,965,997 - 37,990,014 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11437,969,451 - 37,993,302 (-)NCBI
Celera1434,793,332 - 34,814,626 (-)NCBICelera
Cytogenetic Map14p11NCBI
Nipal1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955443584,451 - 609,324 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955443584,451 - 608,451 (-)NCBIChiLan1.0ChiLan1.0
NIPAL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1484,838,778 - 84,862,172 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl484,838,778 - 84,862,170 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0474,106,699 - 74,130,102 (-)NCBIMhudiblu_PPA_v0panPan3
NIPAL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11343,877,377 - 43,900,871 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1343,877,393 - 43,897,671 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1343,829,924 - 43,853,246 (+)NCBI
ROS_Cfam_1.01344,477,241 - 44,500,597 (+)NCBI
UMICH_Zoey_3.11344,154,655 - 44,177,990 (+)NCBI
UNSW_CanFamBas_1.01343,686,663 - 43,709,959 (+)NCBI
UU_Cfam_GSD_1.01344,569,803 - 44,593,134 (+)NCBI
Nipal1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528532,130,309 - 32,150,720 (-)NCBI
SpeTri2.0NW_00493648214,147,716 - 14,168,758 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NIPAL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl837,936,847 - 37,962,908 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1837,936,812 - 37,963,492 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NIPAL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1272,211,034 - 2,231,648 (-)NCBI
ChlSab1.1 Ensembl272,211,562 - 2,231,617 (-)Ensembl
Vero_WHO_p1.0NW_02366604748,224,804 - 48,246,768 (-)NCBI
Nipal1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476118,923,352 - 18,949,288 (-)NCBI

Position Markers
UniSTS:235196  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,670,699 - 72,670,898UniSTSGRCm38
MGSCv37573,061,938 - 73,062,137UniSTSGRCm37
Celera569,919,488 - 69,919,687UniSTS
Cytogenetic Map5C3.2UniSTS
D5Buc48  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,651,840 - 72,652,095UniSTSGRCm38
MGSCv37573,043,079 - 73,043,334UniSTSGRCm37
Celera569,900,628 - 69,900,883UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map5 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5884069387693978Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined31975890100630065Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined31975890100630065Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537424144112317856Mouse
1301698Pcfm4_mperiosteal circumference and femur length 4 (mouse)Not determined54442850078428622Mouse
13207584Mwmlpt4_mMorris water maze latency to platform, training, 4 (mouse)54616526380165263Mouse
13207588Mwmlpa4_mMorris water maze latency to platform, all, 4 (mouse)54616526380165263Mouse
14746981Manh57_mmandible shape 57 (mouse)54701239981012399Mouse
1300854Lmr3_mleishmaniasis resistance 3 (mouse)Not determined55253712081227149Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552537120107173175Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552537120107173175Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554342835126924008Mouse
1301243Bmd2_mbone mineral density 2 (mouse)Not determined555230992100307666Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55230992108614761Mouse
13464248Ahl13_mage related hearing loss, early onset 13 (mouse)55548853189488652Mouse
10043962Obq27_mobesity QTL 27 (mouse)Not determined55612831290128312Mouse
10044005Ahl7_mage related hearing loss 7 (mouse)Not determined55816984192169980Mouse
11040589Lmr3a_mleishmaniasis resistance 3a (mouse)55945495493455133Mouse
11040590Lmr3b_mleishmaniasis resistance 3b (mouse)55945495493455133Mouse
11040591Lmr3c_mleishmaniasis resistance 3c (mouse)55945495493455133Mouse
11040592Lmr3d_mleishmaniasis resistance 3d (mouse)55945495493455133Mouse
1301843Listr1_mlisteriosis resistance 1 (mouse)Not determined56009823494098356Mouse
13464247Ahl14_mage related hearing loss, early onset 14 (mouse)56025521594255313Mouse
4142428Modvl1_mmodifier of vacuolated lens 1 (mouse)Not determined6250272196502841Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56250272196502841Mouse
11252124Modvl6_mmodifier of vacuolated lens 6 (mouse)56250272196502841Mouse
13464250Ahl15_mage related hearing loss, early onset 15 (mouse)56250272196502841Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563548099104239199Mouse
11049560Lmr24d_mleishmaniasis resistance 24d (mouse)56422703098227149Mouse
12904739M2fscn2_mmodifier 2 of FSCN2 (mouse)566381814100381814Mouse
12904740M1fscn2_mmodifier 1 of Fscn2 (mouse)566381814100381814Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)569900000132500000Mouse
10043993Hbnr10_mHeligmosomoides bakeri nematode resistance 10 (mouse)Not determined572271017106271152Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1398
Count of miRNA genes:621
Interacting mature miRNAs:779
Transcripts:ENSMUST00000087212
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000087212   ⟹   ENSMUSP00000084462
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl572,805,138 - 72,828,421 (+)Ensembl
GRCm38.p6 Ensembl572,647,795 - 72,671,078 (+)Ensembl
RefSeq Acc Id: ENSMUST00000197772
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl572,805,185 - 72,816,478 (+)Ensembl
GRCm38.p6 Ensembl572,647,842 - 72,659,135 (+)Ensembl
RefSeq Acc Id: ENSMUST00000197837   ⟹   ENSMUSP00000143667
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl572,805,156 - 72,824,966 (+)Ensembl
GRCm38.p6 Ensembl572,647,813 - 72,667,623 (+)Ensembl
RefSeq Acc Id: NM_001081205   ⟹   NP_001074674
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39572,805,139 - 72,828,421 (+)NCBI
GRCm38572,647,796 - 72,671,078 (+)ENTREZGENE
MGSCv37573,039,035 - 73,062,317 (+)RGD
Celera569,896,584 - 69,919,867 (+)RGD
cM Map5 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001074674   ⟸   NM_001081205
- UniProtKB: Q8BMW7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000143667   ⟸   ENSMUST00000197837
RefSeq Acc Id: ENSMUSP00000084462   ⟸   ENSMUST00000087212

Promoters
RGD ID:6886858
Promoter ID:EPDNEW_M6880
Type:initiation region
Name:Nipal1_1
Description:Mus musculus NIPA-like domain containing 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38572,647,846 - 72,647,906EPDNEW
RGD ID:6837970
Promoter ID:MM_KWN:42527
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001081205,   UC008XRU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36573,038,801 - 73,039,301 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917951 AgrOrtholog
Ensembl Genes ENSMUSG00000067219 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000084462 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000143667 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000087212 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000197837 UniProtKB/TrEMBL
InterPro Mg_trans_NIPA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:70701 UniProtKB/Swiss-Prot
MGD MGI:1917951 ENTREZGENE
NCBI Gene 70701 ENTREZGENE
PANTHER PTHR12570 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Mg_trans_NIPA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nipal1 PhenoGen
UniProt A0A0G2JGR4_MOUSE UniProtKB/TrEMBL
  NIPA3_MOUSE UniProtKB/Swiss-Prot
  Q05A16_MOUSE UniProtKB/TrEMBL
  Q3TR69_MOUSE UniProtKB/TrEMBL
  Q8BMW7 ENTREZGENE