HSD11B1 Human (+)-catechin multiple interactions EXP 6480464 Catechin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of HSD11B1 mRNA] CTD PMID:29935159 HSD11B1 Human (1->4)-beta-D-glucan multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of HSD11B1 mRNA CTD PMID:36331819 HSD11B1 Human (S)-nicotine increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Nicotine results in increased expression of HSD11B1 mRNA CTD PMID:22265867 and PMID:26803847 HSD11B1 Human (S)-nicotine affects expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Nicotine affects the expression of HSD11B1 mRNA CTD PMID:31972234 HSD11B1 Human (S)-nicotine multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 ursodoxicoltaurine inhibits the reaction [Nicotine results in increased expression of HSD11B1 mRNA] CTD PMID:26803847 HSD11B1 Human (S)-nicotine increases expression ISO Hsd11b1 (Mus musculus) 6480464 Nicotine results in increased expression of HSD11B1 mRNA CTD PMID:21955143 HSD11B1 Human 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases activity EXP 6480464 2 more ... CTD PMID:23333641 HSD11B1 Human 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:19414516 HSD11B1 Human 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases activity ISO Hsd11b1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:23333641 HSD11B1 Human 1,2-dimethylhydrazine multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HSD11B1 mRNA CTD PMID:22206623 HSD11B1 Human 11-dehydrocorticosterone multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [HSD11B1 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone more ... CTD PMID:23814014 and PMID:26859423 HSD11B1 Human 11-dehydrocorticosterone affects response to substance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene affects the susceptibility to 11-dehydrocorticosterone CTD PMID:16751407 HSD11B1 Human 11-dehydrocorticosterone affects abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form affects the abundance of 11-dehydrocorticosterone CTD PMID:25061560 HSD11B1 Human 11-dehydrocorticosterone increases metabolic processing ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 protein results in increased metabolism of 11-dehydrocorticosterone CTD PMID:16751407 HSD11B1 Human 11-dehydrocorticosterone increases reduction ISO Hsd11b1 (Rattus norvegicus) 6480464 HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone CTD PMID:26859423 HSD11B1 Human 11-dehydrocorticosterone increases metabolic processing ISO Hsd11b1 (Rattus norvegicus) 6480464 HSD11B1 protein results in increased metabolism of 11-dehydrocorticosterone CTD PMID:23814014 HSD11B1 Human 17alpha-ethynylestradiol multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSD11B1 mRNA CTD PMID:17942748 HSD11B1 Human 17alpha-ethynylestradiol multiple interactions EXP 6480464 Ethinyl Estradiol inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:28257955 HSD11B1 Human 17alpha-ethynylestradiol decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in decreased expression of HSD11B1 mRNA CTD PMID:29097150 HSD11B1 Human 17alpha-ethynylestradiol increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of HSD11B1 mRNA CTD PMID:12655037 more ... HSD11B1 Human 17beta-estradiol decreases activity ISO Hsd11b1 (Rattus norvegicus) 6480464 Estradiol results in decreased activity of HSD11B1 protein CTD PMID:23814014 HSD11B1 Human 17beta-estradiol increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Estradiol results in increased expression of HSD11B1 mRNA and Estradiol results in increased expression of HSD11B1 protein CTD PMID:32145629 HSD11B1 Human 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with NAD] binds to HSD11B1 protein and [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of HSD11B1 protein CTD PMID:23275455 and PMID:25526675 HSD11B1 Human 17beta-estradiol decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Estradiol results in decreased expression of HSD11B1 mRNA CTD PMID:19484750 HSD11B1 Human 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:32784060 HSD11B1 Human 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:33581290 HSD11B1 Human 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [2 more ... CTD PMID:33581290 HSD11B1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Hsd11b1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of HSD11B1 mRNA CTD PMID:17035482 HSD11B1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of HSD11B1 mRNA CTD PMID:32109520 HSD11B1 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of HSD11B1 mRNA CTD PMID:21998131 and PMID:23669205 HSD11B1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Hsd11b1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of HSD11B1 mRNA CTD PMID:21570461 HSD11B1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of HSD11B1 mRNA CTD PMID:22298810 HSD11B1 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of HSD11B1 mRNA CTD PMID:16960034 and PMID:21215274 HSD11B1 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17942748 more ... HSD11B1 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of HSD11B1 mRNA CTD PMID:16960034 HSD11B1 Human 2,3,7,8-Tetrachlorodibenzofuran increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:32109520 HSD11B1 Human 2,4,6-trinitrobenzenesulfonic acid increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of HSD11B1 mRNA CTD PMID:21513799 HSD11B1 Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Hsd11b1 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 HSD11B1 Human 2,6-dinitrotoluene affects expression ISO Hsd11b1 (Rattus norvegicus) 6480464 2 and 6-dinitrotoluene affects the expression of HSD11B1 mRNA CTD PMID:21346803 HSD11B1 Human 2-hydroxypropanoic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of HSD11B1 mRNA CTD PMID:30851411 HSD11B1 Human 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 3 more ... CTD PMID:23196670 HSD11B1 Human 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:35618242 HSD11B1 Human 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 3 more ... CTD PMID:19467301 HSD11B1 Human 3,3',5,5'-tetrabromobisphenol A decreases activity EXP 6480464 tetrabromobisphenol A results in decreased activity of HSD11B1 protein CTD PMID:38189224 HSD11B1 Human 3,3',5,5'-tetrabromobisphenol A decreases activity ISO Hsd11b1 (Rattus norvegicus) 6480464 tetrabromobisphenol A results in decreased activity of HSD11B1 protein CTD PMID:38189224 HSD11B1 Human 3,4-methylenedioxymethamphetamine increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of HSD11B1 mRNA CTD PMID:30071829 HSD11B1 Human 3,7-dihydropurine-6-thione increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Mercaptopurine results in increased expression of HSD11B1 mRNA CTD PMID:23358152 HSD11B1 Human 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of HSD11B1 mRNA more ... CTD PMID:19186324 and PMID:28628672 HSD11B1 Human 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanic acid increases abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form results in increased abundance of 7-ketodeoxycholic acid CTD PMID:25061560 HSD11B1 Human 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of HSD11B1 mRNA and bisphenol S results in increased expression of HSD11B1 protein CTD PMID:27685785 and PMID:34186270 HSD11B1 Human 4,4'-sulfonyldiphenol decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 bisphenol S results in decreased expression of HSD11B1 mRNA CTD PMID:37357847 HSD11B1 Human 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of HSD11B1 mRNA CTD PMID:28628672 HSD11B1 Human 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases reduction EXP 6480464 HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:28257955 HSD11B1 Human 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions EXP 6480464 drospirenone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] more ... CTD PMID:28257955 HSD11B1 Human 4-hydroxyphenyl retinamide decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Fenretinide results in decreased expression of HSD11B1 mRNA CTD PMID:28973697 HSD11B1 Human 4-nonylphenol decreases activity EXP 6480464 4-nonylphenol results in decreased activity of HSD11B1 protein CTD PMID:16184081 HSD11B1 Human 4-tert-Octylphenol decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 4-tert-octylphenol results in decreased expression of HSD11B1 mRNA CTD PMID:17011747 HSD11B1 Human 4-tert-Octylphenol increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 4-tert-octylphenol results in increased expression of HSD11B1 mRNA CTD PMID:17011747 HSD11B1 Human 6-propyl-2-thiouracil decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of HSD11B1 mRNA CTD PMID:24780913 HSD11B1 Human 6-propyl-2-thiouracil multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of HSD11B1 mRNA CTD PMID:36706583 HSD11B1 Human 6alpha-methylprednisolone decreases expression EXP 6480464 Methylprednisolone results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 HSD11B1 Human 7-oxolithocholic acid multiple interactions EXP 6480464 [HSD11B1 protein results in increased reduction of 7-ketolithocholic acid] which results in increased chemical synthesis of Chenodeoxycholic Acid and [HSD11B1 protein results in increased reduction of 7-ketolithocholic acid] which results in increased chemical synthesis of Ursodeoxycholic Acid CTD PMID:21453287 HSD11B1 Human 7-oxolithocholic acid increases reduction EXP 6480464 HSD11B1 protein results in increased reduction of 7-ketolithocholic acid CTD PMID:21453287 HSD11B1 Human 8-Br-cAMP multiple interactions EXP 6480464 4'-cyanobiphenyl-4-sulfonic acid (6-aminopyridin-2-yl)amide inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA] more ... CTD PMID:23275455 HSD11B1 Human 9-cis-retinoic acid decreases expression EXP 6480464 Alitretinoin results in decreased expression of HSD11B1 mRNA CTD PMID:15982314 HSD11B1 Human acetamide decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 acetamide results in decreased expression of HSD11B1 mRNA CTD PMID:31881176 HSD11B1 Human aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of HSD11B1 protein CTD PMID:20106945 HSD11B1 Human aflatoxin B1 increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of HSD11B1 mRNA CTD PMID:33354967 HSD11B1 Human aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of HSD11B1 mRNA CTD PMID:22100608 and PMID:27153756 HSD11B1 Human ammonium chloride affects expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of HSD11B1 mRNA CTD PMID:16483693 HSD11B1 Human androstane-3,17-diol affects binding EXP 6480464 Androstane-3 and 17-diol binds to HSD11B1 protein CTD PMID:25526675 HSD11B1 Human androstane-3,17-diol multiple interactions EXP 6480464 [Androstane-3 and 17-diol co-treated with NAD] binds to HSD11B1 protein CTD PMID:25526675 HSD11B1 Human arsenic acid affects methylation ISO Hsd11b1 (Mus musculus) 6480464 arsenic acid affects the methylation of HSD11B1 gene CTD PMID:26855884 HSD11B1 Human atrazine decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Atrazine results in decreased expression of HSD11B1 mRNA CTD PMID:36841081 HSD11B1 Human azathioprine decreases expression EXP 6480464 Azathioprine results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 HSD11B1 Human benzamide decreases activity EXP 6480464 benzamide analog results in decreased activity of HSD11B1 protein CTD PMID:18553955 more ... HSD11B1 Human benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of HSD11B1 mRNA CTD PMID:20106945 and PMID:32234424 HSD11B1 Human benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of HSD11B1 5' UTR and Benzo(a)pyrene results in increased methylation of HSD11B1 promoter CTD PMID:27901495 HSD11B1 Human benzo[a]pyrene decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of HSD11B1 mRNA CTD PMID:23735875 HSD11B1 Human benzo[a]pyrene multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:18711122 HSD11B1 Human benzo[a]pyrene affects expression ISO Hsd11b1 (Mus musculus) 6480464 Benzo(a)pyrene affects the expression of HSD11B1 mRNA CTD PMID:22342234 HSD11B1 Human benzo[a]pyrene increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Benzo(a)pyrene results in increased expression of HSD11B1 mRNA CTD PMID:21839799 HSD11B1 Human benzo[a]pyrene diol epoxide I affects expression EXP 6480464 7 more ... CTD PMID:20382639 HSD11B1 Human benzo[b]fluoranthene multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of HSD11B1 mRNA CTD PMID:18711122 HSD11B1 Human bezafibrate decreases activity ISO Hsd11b1 (Mus musculus) 6480464 Bezafibrate results in decreased activity of HSD11B1 protein CTD PMID:17190905 HSD11B1 Human bezafibrate decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Bezafibrate results in decreased expression of HSD11B1 mRNA CTD PMID:17190905 HSD11B1 Human bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of HSD11B1 mRNA CTD PMID:25102026 HSD11B1 Human bis(2-ethylhexyl) adipate decreases activity EXP 6480464 dioctyl adipate results in decreased activity of HSD11B1 protein CTD PMID:16184081 HSD11B1 Human bis(2-ethylhexyl) phthalate decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of HSD11B1 mRNA CTD PMID:19245819 HSD11B1 Human bis(2-ethylhexyl) phthalate multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:32784060 HSD11B1 Human bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of HSD11B1 gene CTD PMID:22576693 HSD11B1 Human bisphenol A multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:32784060 HSD11B1 Human bisphenol A affects binding EXP 6480464 bisphenol A binds to HSD11B1 protein CTD PMID:34706627 HSD11B1 Human bisphenol A increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of HSD11B1 mRNA and bisphenol A results in increased expression of HSD11B1 protein CTD PMID:29524480 and PMID:32145629 HSD11B1 Human bisphenol A decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 bisphenol A analog results in decreased expression of HSD11B1 mRNA more ... CTD PMID:30816183 and PMID:35427877 HSD11B1 Human bisphenol A increases methylation ISO Hsd11b1 (Mus musculus) 6480464 bisphenol A results in increased methylation of HSD11B1 promoter CTD PMID:27312807 HSD11B1 Human bisphenol A increases methylation ISO Hsd11b1 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of HSD11B1 gene CTD PMID:28505145 HSD11B1 Human bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of HSD11B1 mRNA CTD PMID:23090578 and PMID:27685785 HSD11B1 Human bisphenol A affects expression ISO Hsd11b1 (Rattus norvegicus) 6480464 bisphenol A affects the expression of HSD11B1 mRNA CTD PMID:25181051 and PMID:30903817 HSD11B1 Human bisphenol A increases expression ISO Hsd11b1 (Mus musculus) 6480464 bisphenol A results in increased expression of HSD11B1 mRNA CTD PMID:26063408 more ... HSD11B1 Human bisphenol A decreases activity ISO Hsd11b1 (Rattus norvegicus) 6480464 bisphenol A results in decreased activity of HSD11B1 protein CTD PMID:23069880 HSD11B1 Human bisphenol A decreases activity EXP 6480464 bisphenol A results in decreased activity of HSD11B1 protein CTD PMID:23069880 HSD11B1 Human bisphenol A increases activity EXP 6480464 bisphenol A results in increased activity of HSD11B1 protein CTD PMID:23090578 HSD11B1 Human bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of HSD11B1 mRNA and bisphenol A results in decreased expression of HSD11B1 protein CTD PMID:22576693 and PMID:34186270 HSD11B1 Human bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of HSD11B1 gene and Mifepristone inhibits the reaction [bisphenol A results in increased expression of HSD11B1 mRNA] CTD PMID:23090578 and PMID:31601247 HSD11B1 Human Bisphenol B increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 bisphenol B results in increased expression of HSD11B1 protein CTD PMID:33940105 HSD11B1 Human Bisphenol B increases expression EXP 6480464 bisphenol B results in increased expression of HSD11B1 protein CTD PMID:34186270 HSD11B1 Human Butylbenzyl phthalate increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 butylbenzyl phthalate results in increased expression of HSD11B1 protein CTD PMID:31319113 HSD11B1 Human cadmium dichloride increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of HSD11B1 mRNA CTD PMID:33453195 HSD11B1 Human cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of HSD11B1 mRNA CTD PMID:38568856 HSD11B1 Human caffeine increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Caffeine results in increased expression of HSD11B1 mRNA CTD PMID:22583948 more ... HSD11B1 Human calcitriol multiple interactions EXP 6480464 [Calcitriol co-treated with Cortisone] results in increased expression of HSD11B1 mRNA CTD PMID:19918113 HSD11B1 Human calcitriol affects expression EXP 6480464 Calcitriol affects the expression of HSD11B1 protein CTD PMID:19918113 HSD11B1 Human CARBENOXOLONE multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 Carbenoxolone inhibits the reaction [Lipopolysaccharides results in increased expression of HSD11B1 mRNA] CTD PMID:27523796 HSD11B1 Human CARBENOXOLONE decreases activity ISO Hsd11b1 (Rattus norvegicus) 6480464 Carbenoxolone results in decreased activity of HSD11B1 protein CTD PMID:23814014 HSD11B1 Human CARBENOXOLONE decreases activity ISO Hsd11b1 (Mus musculus) 6480464 Carbenoxolone results in decreased activity of HSD11B1 protein CTD PMID:24135201 HSD11B1 Human CARBENOXOLONE decreases activity EXP 6480464 Carbenoxolone results in decreased activity of HSD11B1 protein CTD PMID:24135201 HSD11B1 Human carbon nanotube increases expression EXP 6480464 Nanotubes and Carbon results in increased expression of HSD11B1 mRNA CTD PMID:29348435 HSD11B1 Human chenodeoxycholic acid decreases activity EXP 6480464 Chenodeoxycholic Acid results in decreased activity of HSD11B1 protein CTD PMID:10664531 HSD11B1 Human chenodeoxycholic acid increases abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form results in increased abundance of Chenodeoxycholic Acid CTD PMID:25061560 HSD11B1 Human chenodeoxycholic acid multiple interactions EXP 6480464 [HSD11B1 protein results in increased reduction of 7-ketolithocholic acid] which results in increased chemical synthesis of Chenodeoxycholic Acid CTD PMID:21453287 HSD11B1 Human cholic acid increases abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form results in increased abundance of Cholic Acid CTD PMID:25061560 HSD11B1 Human chromium atom increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Chromium deficiency results in increased expression of HSD11B1 mRNA CTD PMID:19846803 HSD11B1 Human cisplatin increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Cisplatin results in increased expression of HSD11B1 protein CTD PMID:22023808 HSD11B1 Human clofibrate decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Clofibrate results in decreased expression of HSD11B1 mRNA CTD PMID:17585979 HSD11B1 Human clofibrate decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Clofibrate results in decreased expression of HSD11B1 mRNA CTD PMID:12851107 HSD11B1 Human clofibrate multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of HSD11B1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HSD11B1 mRNA] CTD PMID:17585979 HSD11B1 Human clofibric acid decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Clofibric Acid results in decreased expression of HSD11B1 mRNA CTD PMID:15833021 HSD11B1 Human clofibric acid multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [Clofibric Acid co-treated with Diethylnitrosamine] results in decreased expression of HSD11B1 mRNA CTD PMID:15833021 HSD11B1 Human copper(II) chloride increases expression EXP 6480464 cupric chloride results in increased expression of HSD11B1 mRNA CTD PMID:38568856 HSD11B1 Human cordycepin decreases expression ISO Hsd11b1 (Mus musculus) 6480464 cordycepin results in decreased expression of HSD11B1 mRNA CTD PMID:20107539 HSD11B1 Human corticosterone increases chemical synthesis ISO Hsd11b1 (Rattus norvegicus) 6480464 HSD11B1 protein results in increased chemical synthesis of Corticosterone CTD PMID:23814014 HSD11B1 Human corticosterone multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [[trimethyltin chloride results in increased abundance of trimethyltin] which co-treated with Corticosterone] results in increased expression of HSD11B1 mRNA more ... CTD PMID:30993381 HSD11B1 Human corticosterone increases oxidation ISO Hsd11b1 (Rattus norvegicus) 6480464 HSD11B1 protein results in increased oxidation of Corticosterone CTD PMID:26859423 HSD11B1 Human corticosterone decreases abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form results in decreased abundance of Corticosterone CTD PMID:25061560 HSD11B1 Human corticosterone increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Corticosterone results in increased expression of HSD11B1 mRNA CTD PMID:15755911 HSD11B1 Human corticosterone increases chemical synthesis ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 protein results in increased chemical synthesis of Corticosterone CTD PMID:16751407 HSD11B1 Human corticosterone multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [HSD11B1 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone more ... CTD PMID:23814014 and PMID:26859423 HSD11B1 Human cortisol multiple interactions EXP 6480464 [HSD11B1 protein results in increased metabolism of Ketosteroids] which results in increased chemical synthesis of Hydrocortisone more ... CTD PMID:17761898 more ... HSD11B1 Human cortisol affects expression EXP 6480464 Hydrocortisone affects the expression of HSD11B1 mRNA CTD PMID:30528684 HSD11B1 Human cortisol increases oxidation EXP 6480464 HSD11B1 protein results in increased oxidation of Hydrocortisone CTD PMID:26859423 HSD11B1 Human cortisol multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [HSD11B1 protein affects the susceptibility to Hydrocortisone] which results in decreased activity of NFE2L2 protein CTD PMID:22606287 HSD11B1 Human cortisol affects response to substance ISO Hsd11b1 (Rattus norvegicus) 6480464 HSD11B1 protein affects the susceptibility to Hydrocortisone CTD PMID:22606287 HSD11B1 Human cortisol increases chemical synthesis EXP 6480464 HSD11B1 protein results in increased chemical synthesis of Hydrocortisone CTD PMID:16054388 more ... HSD11B1 Human cortisol increases expression EXP 6480464 Hydrocortisone results in increased expression of HSD11B1 more ... CTD PMID:16054388 more ... HSD11B1 Human cortisol increases activity EXP 6480464 Hydrocortisone results in increased activity of HSD11B1 protein CTD PMID:20410225 HSD11B1 Human cortisol affects oxidation EXP 6480464 HSD11B1 protein affects the oxidation of Hydrocortisone CTD PMID:17761898 HSD11B1 Human cortisone multiple interactions EXP 6480464 [Calcitriol co-treated with Cortisone] results in increased expression of HSD11B1 mRNA more ... CTD PMID:19918113 more ... HSD11B1 Human cortisone increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Cortisone results in increased expression of HSD11B1 mRNA CTD PMID:30993381 HSD11B1 Human cortisone increases reduction EXP 6480464 HSD11B1 protein results in increased reduction of Cortisone CTD PMID:26859423 HSD11B1 Human cortisone affects response to substance ISO Hsd11b1 (Rattus norvegicus) 6480464 HSD11B1 protein affects the susceptibility to Cortisone CTD PMID:22606287 HSD11B1 Human cortisone increases expression ISO Hsd11b1 (Mus musculus) 6480464 Cortisone results in increased expression of HSD11B1 mRNA CTD PMID:24135201 HSD11B1 Human cortisone multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [HSD11B1 protein affects the susceptibility to Cortisone] which results in decreased activity of NFE2L2 protein more ... CTD PMID:22606287 and PMID:30993381 HSD11B1 Human cortisone multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 2-(3-benzoyl)-4-hydroxy-1 more ... CTD PMID:21315688 HSD11B1 Human cortisone increases metabolic processing EXP 6480464 HSD11B1 protein results in increased metabolism of Cortisone CTD PMID:16751407 HSD11B1 Human cortisone affects metabolic processing EXP 6480464 HSD11B1 protein affects the metabolism of Cortisone CTD PMID:16054388 HSD11B1 Human crocidolite asbestos increases expression EXP 6480464 Asbestos and Crocidolite results in increased expression of HSD11B1 mRNA CTD PMID:25351596 HSD11B1 Human crocidolite asbestos decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Asbestos and Crocidolite results in decreased expression of HSD11B1 mRNA CTD PMID:29279043 HSD11B1 Human Cuprizon decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Cuprizone results in decreased expression of HSD11B1 mRNA CTD PMID:26577399 HSD11B1 Human cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of HSD11B1 mRNA CTD PMID:20106945 HSD11B1 Human cyhalothrin decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 cyhalothrin results in decreased expression of HSD11B1 mRNA and cyhalothrin results in decreased expression of HSD11B1 protein CTD PMID:30029170 HSD11B1 Human deoxycholic acid increases abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form results in increased abundance of Deoxycholic Acid CTD PMID:25061560 HSD11B1 Human dexamethasone multiple interactions EXP 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of HSD11B1 mRNA more ... CTD PMID:19186324 more ... HSD11B1 Human dexamethasone increases expression ISO Hsd11b1 (Mus musculus) 6480464 Dexamethasone results in increased expression of HSD11B1 mRNA CTD PMID:19344079 and PMID:22733784 HSD11B1 Human dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of HSD11B1 mRNA CTD PMID:19853017 HSD11B1 Human dexamethasone affects expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Dexamethasone affects the expression of HSD11B1 mRNA CTD PMID:15102944 HSD11B1 Human dextran sulfate multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HSD11B1 mRNA CTD PMID:29950665 HSD11B1 Human dextran sulfate increases expression ISO Hsd11b1 (Mus musculus) 6480464 Dextran Sulfate results in increased expression of HSD11B1 mRNA CTD PMID:35093514 HSD11B1 Human Di-n-hexyl phthalate decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 di-n-hexyl phthalate results in decreased expression of HSD11B1 protein CTD PMID:32693021 HSD11B1 Human dibenz[a,h]anthracene multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [1 more ... CTD PMID:18711122 HSD11B1 Human dibenzo[a,l]pyrene multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [1 more ... CTD PMID:18711122 HSD11B1 Human dibutyl phthalate increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in increased expression of HSD11B1 protein CTD PMID:19815848 HSD11B1 Human dibutyl phthalate decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in decreased expression of HSD11B1 mRNA CTD PMID:28528174 HSD11B1 Human dichloroacetic acid decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Dichloroacetic Acid results in decreased expression of HSD11B1 mRNA CTD PMID:28962523 HSD11B1 Human Dicyclohexyl phthalate decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 dicyclohexyl phthalate results in decreased expression of HSD11B1 mRNA and dicyclohexyl phthalate results in decreased expression of HSD11B1 protein CTD PMID:30391266 HSD11B1 Human diethyl hydrogen phosphate decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 diethyl phosphate results in decreased expression of HSD11B1 mRNA CTD PMID:35777568 HSD11B1 Human diethylstilbestrol increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Diethylstilbestrol results in increased expression of HSD11B1 mRNA CTD PMID:17011747 HSD11B1 Human diiodine multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of HSD11B1 mRNA CTD PMID:36706583 HSD11B1 Human disulfiram multiple interactions EXP 6480464 [Disulfiram co-treated with NAD] binds to HSD11B1 protein CTD PMID:25526675 HSD11B1 Human diuron increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Diuron results in increased expression of HSD11B1 mRNA CTD PMID:21551480 HSD11B1 Human doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of HSD11B1 mRNA CTD PMID:29803840 HSD11B1 Human drospirenone multiple interactions EXP 6480464 drospirenone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:28257955 HSD11B1 Human ethanol decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Ethanol results in decreased expression of HSD11B1 mRNA CTD PMID:21955143 HSD11B1 Human ethanol increases expression ISO Hsd11b1 (Mus musculus) 6480464 Ethanol results in increased expression of HSD11B1 mRNA CTD PMID:30319688 HSD11B1 Human ethanol multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 Ethanol affects the reaction [Dietary Fats affects the expression of HSD11B1 mRNA] CTD PMID:31811911 HSD11B1 Human ethanol affects expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Ethanol affects the expression of HSD11B1 mRNA CTD PMID:31039417 HSD11B1 Human ethanol increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Ethanol results in increased expression of HSD11B1 mRNA CTD PMID:26188107 and PMID:32535229 HSD11B1 Human fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of HSD11B1 mRNA CTD PMID:25572481 HSD11B1 Human fenthion increases expression ISO Hsd11b1 (Mus musculus) 6480464 Fenthion results in increased expression of HSD11B1 mRNA CTD PMID:34813904 HSD11B1 Human ferric oxide increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 ferric oxide analog results in increased expression of HSD11B1 mRNA CTD PMID:38615722 HSD11B1 Human fipronil multiple interactions EXP 6480464 [fipronil co-treated with DEET] results in decreased expression of HSD11B1 mRNA CTD PMID:27091632 HSD11B1 Human fluoranthene multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [1 more ... CTD PMID:18711122 HSD11B1 Human folic acid multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HSD11B1 mRNA CTD PMID:22206623 HSD11B1 Human fulvestrant multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of HSD11B1 gene CTD PMID:31601247 HSD11B1 Human fumonisin B1 decreases expression ISO Hsd11b1 (Mus musculus) 6480464 fumonisin B1 results in decreased expression of HSD11B1 mRNA CTD PMID:16221962 HSD11B1 Human furan increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 furan results in increased expression of HSD11B1 mRNA CTD PMID:26194646 HSD11B1 Human furosemide decreases activity ISO Hsd11b1 (Rattus norvegicus) 6480464 Furosemide results in decreased activity of HSD11B1 protein CTD PMID:11749789 HSD11B1 Human genistein decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Genistein results in decreased expression of HSD11B1 mRNA CTD PMID:21782745 HSD11B1 Human genistein decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Genistein results in decreased expression of HSD11B1 mRNA CTD PMID:32186404 HSD11B1 Human glycochenodeoxycholic acid decreases abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form results in decreased abundance of Glycochenodeoxycholic Acid CTD PMID:25061560 HSD11B1 Human glycolithocholic acid decreases abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form results in decreased abundance of glycolithocholic acid CTD PMID:25061560 HSD11B1 Human glycyrrhetinate decreases activity EXP 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B1 protein CTD PMID:24135201 HSD11B1 Human glycyrrhetinate decreases activity ISO Hsd11b1 (Mus musculus) 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B1 protein CTD PMID:24135201 HSD11B1 Human glycyrrhetinic acid decreases activity ISO Hsd11b1 (Mus musculus) 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B1 protein CTD PMID:24135201 HSD11B1 Human glycyrrhetinic acid decreases activity EXP 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B1 protein CTD PMID:24135201 HSD11B1 Human herbicide multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides and Industrial co-treated with Herbicides]] results in decreased expression of HSD11B1 mRNA CTD PMID:25588985 HSD11B1 Human hyodeoxycholic acid increases abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form results in increased abundance of hyodeoxycholic acid CTD PMID:25061560 HSD11B1 Human indometacin multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of HSD11B1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of HSD11B1 mRNA CTD PMID:28628672 HSD11B1 Human inulin multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of HSD11B1 mRNA CTD PMID:36331819 HSD11B1 Human isotretinoin decreases expression EXP 6480464 Isotretinoin results in decreased expression of HSD11B1 mRNA CTD PMID:15982314 and PMID:20436886 HSD11B1 Human kainic acid decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Kainic Acid results in decreased expression of HSD11B1 mRNA CTD PMID:17997037 HSD11B1 Human ketamine increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Ketamine results in increased expression of HSD11B1 mRNA CTD PMID:20080153 HSD11B1 Human lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of HSD11B1 mRNA CTD PMID:38568856 HSD11B1 Human lipopolysaccharide multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 2-(3-benzoyl)-4-hydroxy-1 more ... CTD PMID:27523796 HSD11B1 Human lipopolysaccharide increases expression ISO Hsd11b1 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of HSD11B1 mRNA CTD PMID:16847310 and PMID:27523796 HSD11B1 Human manganese(II) chloride increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 manganese chloride results in increased expression of HSD11B1 mRNA CTD PMID:28801915 HSD11B1 Human medroxyprogesterone acetate multiple interactions EXP 6480464 [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of and results in increased activity of HSD11B1 protein and [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA CTD PMID:23275455 HSD11B1 Human mercaptopurine increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Mercaptopurine results in increased expression of HSD11B1 mRNA CTD PMID:23358152 HSD11B1 Human methidathion increases expression ISO Hsd11b1 (Mus musculus) 6480464 methidathion results in increased expression of HSD11B1 mRNA CTD PMID:34813904 HSD11B1 Human methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of HSD11B1 mRNA CTD PMID:17400583 HSD11B1 Human methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 HSD11B1 Human methoxychlor decreases activity EXP 6480464 Methoxychlor results in decreased activity of HSD11B1 protein CTD PMID:23333641 HSD11B1 Human metyrapone decreases activity EXP 6480464 Metyrapone results in decreased activity of HSD11B1 protein CTD PMID:10664531 HSD11B1 Human mifepristone multiple interactions EXP 6480464 [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]] more ... CTD PMID:22606287 more ... HSD11B1 Human mifepristone multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 Mifepristone inhibits the reaction [Corticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA]] CTD PMID:30993381 HSD11B1 Human mifepristone multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [HSD11B1 protein results in decreased activity of NFE2L2 protein] CTD PMID:22606287 HSD11B1 Human mono(2-ethylhexyl) phthalate decreases expression ISO Hsd11b1 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of HSD11B1 mRNA CTD PMID:37886449 HSD11B1 Human monosodium L-glutamate multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of HSD11B1 mRNA CTD PMID:19001666 HSD11B1 Human morphine decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Morphine results in decreased expression of HSD11B1 mRNA CTD PMID:21955143 HSD11B1 Human N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [fipronil co-treated with DEET] results in decreased expression of HSD11B1 mRNA CTD PMID:27091632 HSD11B1 Human N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [2 more ... CTD PMID:33581290 HSD11B1 Human N-nitrosodiethylamine multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [Clofibric Acid co-treated with Diethylnitrosamine] results in decreased expression of HSD11B1 mRNA CTD PMID:15833021 HSD11B1 Human N-Nitrosopyrrolidine increases expression EXP 6480464 N-Nitrosopyrrolidine results in increased expression of HSD11B1 mRNA CTD PMID:32234424 HSD11B1 Human NAD zwitterion multiple interactions EXP 6480464 [Androstane-3 more ... CTD PMID:25526675 HSD11B1 Human NAD(+) multiple interactions EXP 6480464 [Androstane-3 more ... CTD PMID:25526675 HSD11B1 Human NADP zwitterion increases oxidation EXP 6480464 HSD11B1 protein results in increased oxidation of NADP CTD PMID:26859423 HSD11B1 Human NADP zwitterion multiple interactions EXP 6480464 NADP binds to and results in increased activity of HSD11B1 protein CTD PMID:25526675 HSD11B1 Human NADP zwitterion increases reduction EXP 6480464 HSD11B1 protein results in increased reduction of NADP CTD PMID:26859423 HSD11B1 Human NADP zwitterion increases reduction ISO Hsd11b1 (Rattus norvegicus) 6480464 HSD11B1 protein results in increased reduction of NADP CTD PMID:26859423 HSD11B1 Human NADP zwitterion increases oxidation ISO Hsd11b1 (Rattus norvegicus) 6480464 HSD11B1 protein results in increased oxidation of NADP CTD PMID:26859423 HSD11B1 Human NADP zwitterion multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 Ziram inhibits the reaction [HSD11B1 protein results in increased oxidation of NADP] CTD PMID:26859423 HSD11B1 Human NADP(+) increases oxidation ISO Hsd11b1 (Rattus norvegicus) 6480464 HSD11B1 protein results in increased oxidation of NADP CTD PMID:26859423 HSD11B1 Human NADP(+) multiple interactions EXP 6480464 NADP binds to and results in increased activity of HSD11B1 protein CTD PMID:25526675 HSD11B1 Human NADP(+) increases reduction EXP 6480464 HSD11B1 protein results in increased reduction of NADP CTD PMID:26859423 HSD11B1 Human NADP(+) increases oxidation EXP 6480464 HSD11B1 protein results in increased oxidation of NADP CTD PMID:26859423 HSD11B1 Human NADP(+) multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 Ziram inhibits the reaction [HSD11B1 protein results in increased oxidation of NADP] CTD PMID:26859423 HSD11B1 Human NADP(+) increases reduction ISO Hsd11b1 (Rattus norvegicus) 6480464 HSD11B1 protein results in increased reduction of NADP CTD PMID:26859423 HSD11B1 Human nickel atom decreases expression EXP 6480464 Nickel results in decreased expression of HSD11B1 mRNA CTD PMID:24768652 HSD11B1 Human nicotine increases expression ISO Hsd11b1 (Mus musculus) 6480464 Nicotine results in increased expression of HSD11B1 mRNA CTD PMID:21955143 HSD11B1 Human nicotine affects expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Nicotine affects the expression of HSD11B1 mRNA CTD PMID:31972234 HSD11B1 Human nicotine multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 ursodoxicoltaurine inhibits the reaction [Nicotine results in increased expression of HSD11B1 mRNA] CTD PMID:26803847 HSD11B1 Human nicotine increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Nicotine results in increased expression of HSD11B1 mRNA CTD PMID:22265867 and PMID:26803847 HSD11B1 Human nitrofen increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 nitrofen results in increased expression of HSD11B1 mRNA CTD PMID:33484710 HSD11B1 Human Nonylphenol multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 nonylphenol results in increased expression of and results in increased activity of HSD11B1 protein CTD PMID:22765982 HSD11B1 Human oxaliplatin multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of HSD11B1 mRNA CTD PMID:25729387 HSD11B1 Human oxaliplatin increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 oxaliplatin results in increased expression of HSD11B1 mRNA CTD PMID:25729387 HSD11B1 Human oxycodone decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Oxycodone results in decreased expression of HSD11B1 mRNA CTD PMID:23439660 HSD11B1 Human ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of HSD11B1 mRNA CTD PMID:26035830 HSD11B1 Human ozone multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of HSD11B1 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of HSD11B1 mRNA CTD PMID:34911549 HSD11B1 Human p-tert-Amylphenol decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 4-tert-octylphenol results in decreased expression of HSD11B1 mRNA CTD PMID:17011747 HSD11B1 Human p-tert-Amylphenol increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 4-tert-octylphenol results in increased expression of HSD11B1 mRNA CTD PMID:17011747 HSD11B1 Human p-toluidine increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 4-toluidine results in increased expression of HSD11B1 mRNA CTD PMID:27638505 HSD11B1 Human paracetamol multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of HSD11B1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HSD11B1 mRNA] CTD PMID:17585979 HSD11B1 Human paracetamol decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of HSD11B1 mRNA CTD PMID:33387578 HSD11B1 Human paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of HSD11B1 mRNA CTD PMID:29067470 HSD11B1 Human paracetamol affects expression ISO Hsd11b1 (Mus musculus) 6480464 Acetaminophen affects the expression of HSD11B1 mRNA CTD PMID:17562736 HSD11B1 Human paraquat increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Paraquat results in increased expression of HSD11B1 mRNA CTD PMID:18198484 HSD11B1 Human paraquat decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Paraquat results in decreased expression of HSD11B1 mRNA and Paraquat results in decreased expression of HSD11B1 protein CTD PMID:31128353 HSD11B1 Human parathion increases expression ISO Hsd11b1 (Mus musculus) 6480464 Parathion results in increased expression of HSD11B1 mRNA CTD PMID:34813904 HSD11B1 Human perfluorododecanoic acid decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 perfluorododecanoic acid results in decreased expression of HSD11B1 mRNA and perfluorododecanoic acid results in decreased expression of HSD11B1 protein CTD PMID:30489073 and PMID:33774092 HSD11B1 Human perfluorononanoic acid multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides and Industrial co-treated with Herbicides]] results in decreased expression of HSD11B1 mRNA CTD PMID:25588985 HSD11B1 Human perfluorooctane-1-sulfonic acid decreases activity EXP 6480464 perfluorooctane sulfonic acid results in decreased activity of HSD11B1 protein CTD PMID:22178014 HSD11B1 Human perfluorooctane-1-sulfonic acid multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of HSD11B1 mRNA more ... CTD PMID:36331819 HSD11B1 Human perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 perfluorooctane sulfonic acid inhibits the reaction [Hydrocortisone results in increased expression of HSD11B1] CTD PMID:27288094 HSD11B1 Human perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of HSD11B1 CTD PMID:27288094 HSD11B1 Human perfluorooctane-1-sulfonic acid decreases activity ISO Hsd11b1 (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in decreased activity of HSD11B1 protein CTD PMID:22178014 HSD11B1 Human perfluorooctanoic acid decreases expression ISO Hsd11b1 (Mus musculus) 6480464 perfluorooctanoic acid results in decreased expression of HSD11B1 mRNA CTD PMID:17681415 and PMID:30711707 HSD11B1 Human perfluorooctanoic acid decreases activity ISO Hsd11b1 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in decreased activity of HSD11B1 protein CTD PMID:22178014 HSD11B1 Human perfluorooctanoic acid decreases activity EXP 6480464 perfluorooctanoic acid results in decreased activity of HSD11B1 protein CTD PMID:22178014 HSD11B1 Human perfluorooctanoic acid decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in decreased expression of HSD11B1 mRNA and perfluorooctanoic acid results in decreased expression of HSD11B1 protein CTD PMID:16221955 more ... HSD11B1 Human perfluoroundecanoic acid decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 perfluoroundecanoic acid results in decreased expression of HSD11B1 mRNA and perfluoroundecanoic acid results in decreased expression of HSD11B1 protein CTD PMID:33549592 and PMID:35143807 HSD11B1 Human phenobarbital increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Phenobarbital results in increased expression of HSD11B1 mRNA CTD PMID:19162173 HSD11B1 Human phorbol 13-acetate 12-myristate increases activity ISO Hsd11b1 (Rattus norvegicus) 6480464 Tetradecanoylphorbol Acetate results in increased activity of HSD11B1 protein CTD PMID:16533503 HSD11B1 Human phorbol 13-acetate 12-myristate increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Tetradecanoylphorbol Acetate results in increased expression of HSD11B1 mRNA CTD PMID:16533503 HSD11B1 Human piperonyl butoxide decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Piperonyl Butoxide results in decreased expression of HSD11B1 mRNA CTD PMID:22484513 HSD11B1 Human pirinixic acid multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [pirinixic acid co-treated with PPARA] results in decreased expression of HSD11B1 mRNA and PPARA protein promotes the reaction [pirinixic acid results in decreased expression of HSD11B1 mRNA] CTD PMID:20059764 and PMID:20813756 HSD11B1 Human pirinixic acid decreases expression ISO Hsd11b1 (Mus musculus) 6480464 pirinixic acid results in decreased expression of HSD11B1 mRNA CTD PMID:11798191 more ... HSD11B1 Human pirinixic acid decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 pirinixic acid results in decreased expression of HSD11B1 mRNA CTD PMID:19162173 and PMID:22484513 HSD11B1 Human piroxicam decreases expression EXP 6480464 Piroxicam results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 HSD11B1 Human prednisolone decreases expression EXP 6480464 Prednisolone results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 HSD11B1 Human pregnenolone 16alpha-carbonitrile increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Pregnenolone Carbonitrile results in increased expression of HSD11B1 mRNA CTD PMID:19162173 HSD11B1 Human progesterone affects expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Progesterone affects the expression of HSD11B1 mRNA and Progesterone affects the expression of HSD11B1 protein CTD PMID:19208548 HSD11B1 Human progesterone multiple interactions EXP 6480464 4'-cyanobiphenyl-4-sulfonic acid (6-aminopyridin-2-yl)amide inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA] more ... CTD PMID:23275455 and PMID:28257955 HSD11B1 Human progesterone increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Progesterone results in increased expression of HSD11B1 mRNA CTD PMID:20726854 HSD11B1 Human progesterone increases expression EXP 6480464 Progesterone results in increased expression of HSD11B1 mRNA CTD PMID:21795739 HSD11B1 Human Propiverine affects binding ISO Hsd11b1 (Rattus norvegicus) 6480464 propiverine binds to HSD11B1 protein CTD PMID:29273565 HSD11B1 Human prostaglandin E2 multiple interactions EXP 6480464 6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [Dinoprostone results in increased activity of HSD11B1 protein] more ... CTD PMID:17761898 HSD11B1 Human prostaglandin E2 increases activity EXP 6480464 Dinoprostone results in increased activity of HSD11B1 protein CTD PMID:17761898 HSD11B1 Human purine-6-thiol increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Mercaptopurine results in increased expression of HSD11B1 mRNA CTD PMID:23358152 HSD11B1 Human pyrazinecarboxamide increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Pyrazinamide results in increased expression of HSD11B1 mRNA CTD PMID:22431067 HSD11B1 Human quercetin multiple interactions EXP 6480464 [Quercetin co-treated with NAD] binds to HSD11B1 protein CTD PMID:25526675 HSD11B1 Human rac-lactic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of HSD11B1 mRNA CTD PMID:30851411 HSD11B1 Human resveratrol decreases activity ISO Hsd11b1 (Mus musculus) 6480464 resveratrol results in decreased activity of HSD11B1 protein CTD PMID:23814014 HSD11B1 Human resveratrol decreases activity ISO Hsd11b1 (Rattus norvegicus) 6480464 resveratrol results in decreased activity of HSD11B1 protein CTD PMID:23814014 HSD11B1 Human resveratrol multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 resveratrol inhibits the reaction [HSD11B1 protein results in increased chemical synthesis of Corticosterone] and resveratrol inhibits the reaction [HSD11B1 protein results in increased metabolism of 11-dehydrocorticosterone] CTD PMID:23814014 HSD11B1 Human SB 203580 multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 SB 203580 inhibits the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA] CTD PMID:30993381 HSD11B1 Human serpentine asbestos increases expression EXP 6480464 Asbestos and Serpentine results in increased expression of HSD11B1 mRNA CTD PMID:24160326 HSD11B1 Human serpentine asbestos decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Asbestos and Serpentine results in decreased expression of HSD11B1 mRNA CTD PMID:16251409 HSD11B1 Human silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of HSD11B1 mRNA CTD PMID:25351596 HSD11B1 Human sodium arsenate decreases glycosylation ISO Hsd11b1 (Mus musculus) 6480464 sodium arsenate results in decreased glycosylation of HSD11B1 protein CTD PMID:22960421 HSD11B1 Human sodium arsenite decreases expression ISO Hsd11b1 (Mus musculus) 6480464 sodium arsenite results in decreased expression of HSD11B1 mRNA CTD PMID:17350061 and PMID:37682722 HSD11B1 Human sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of HSD11B1 mRNA CTD PMID:38568856 HSD11B1 Human sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of HSD11B1 mRNA CTD PMID:29301061 HSD11B1 Human sodium aurothiomalate decreases expression EXP 6480464 Gold Sodium Thiomalate results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 HSD11B1 Human spironolactone multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 Spironolactone inhibits the reaction [Corticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA]] CTD PMID:30993381 HSD11B1 Human sulforaphane multiple interactions EXP 6480464 [HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein] and [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]] CTD PMID:22606287 HSD11B1 Human taurolithocholic acid increases abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form results in increased abundance of Taurolithocholic Acid CTD PMID:25061560 HSD11B1 Human tauroursodeoxycholic acid decreases abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form results in decreased abundance of ursodoxicoltaurine CTD PMID:25061560 HSD11B1 Human tauroursodeoxycholic acid decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 ursodoxicoltaurine results in decreased expression of HSD11B1 mRNA CTD PMID:15885361 HSD11B1 Human tauroursodeoxycholic acid multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 ursodoxicoltaurine inhibits the reaction [Nicotine results in increased expression of HSD11B1 mRNA] CTD PMID:26803847 HSD11B1 Human tenofovir disoproxil fumarate affects expression EXP 6480464 Tenofovir affects the expression of HSD11B1 mRNA CTD PMID:20032539 HSD11B1 Human tert-butyl hydroperoxide decreases expression EXP 6480464 tert-Butylhydroperoxide results in decreased expression of HSD11B1 mRNA CTD PMID:29935159 HSD11B1 Human tert-butyl hydroperoxide multiple interactions EXP 6480464 Catechin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of HSD11B1 mRNA] and Grape Seed Extract inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of HSD11B1 mRNA] CTD PMID:29935159 HSD11B1 Human testosterone increases activity EXP 6480464 Testosterone results in increased activity of HSD11B1 protein CTD PMID:20410225 HSD11B1 Human testosterone multiple interactions EXP 6480464 [Testosterone co-treated with NAD] binds to HSD11B1 protein and Testosterone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:25526675 and PMID:28257955 HSD11B1 Human testosterone increases expression ISO Hsd11b1 (Mus musculus) 6480464 Testosterone results in increased expression of HSD11B1 mRNA CTD PMID:19693291 HSD11B1 Human testosterone increases expression EXP 6480464 Testosterone results in increased expression of HSD11B1 mRNA CTD PMID:20410225 HSD11B1 Human Tetrachlorobisphenol A decreases activity EXP 6480464 tetrachlorodian results in decreased activity of HSD11B1 protein CTD PMID:38189224 HSD11B1 Human tetrachloromethane affects expression ISO Hsd11b1 (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of HSD11B1 mRNA CTD PMID:17484886 HSD11B1 Human tetrachloromethane increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of HSD11B1 mRNA CTD PMID:31150632 HSD11B1 Human tetrachloromethane decreases expression ISO Hsd11b1 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of HSD11B1 mRNA CTD PMID:27339419 and PMID:31919559 HSD11B1 Human thioacetamide decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of HSD11B1 mRNA CTD PMID:34492290 HSD11B1 Human titanium dioxide decreases expression ISO Hsd11b1 (Mus musculus) 6480464 titanium dioxide results in decreased expression of HSD11B1 mRNA CTD PMID:23557971 HSD11B1 Human titanium dioxide multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HSD11B1 mRNA CTD PMID:29950665 HSD11B1 Human topotecan multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of HSD11B1 mRNA CTD PMID:25729387 HSD11B1 Human topotecan increases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Topotecan results in increased expression of HSD11B1 mRNA CTD PMID:25729387 HSD11B1 Human triadimefon increases reduction ISO Hsd11b1 (Rattus norvegicus) 6480464 HSD11B1 protein results in increased reduction of triadimefon CTD PMID:18763812 HSD11B1 Human trimethyltin multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 1 more ... CTD PMID:30993381 HSD11B1 Human trimethyltin multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA more ... CTD PMID:30993381 HSD11B1 Human triphenylstannane multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 [triphenyltin co-treated with ethylene dimethanesulfonate] affects the expression of HSD11B1 mRNA and [triphenyltin co-treated with ethylene dimethanesulfonate] affects the expression of HSD11B1 protein CTD PMID:30772500 HSD11B1 Human triphenylstannane decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 triphenyltin results in decreased expression of HSD11B1 mRNA and triphenyltin results in decreased expression of HSD11B1 protein CTD PMID:31765896 HSD11B1 Human troglitazone decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 troglitazone results in decreased expression of HSD11B1 mRNA CTD PMID:14697232 HSD11B1 Human troglitazone increases expression EXP 6480464 troglitazone results in increased expression of HSD11B1 mRNA CTD PMID:25572481 HSD11B1 Human ursodeoxycholic acid multiple interactions EXP 6480464 [HSD11B1 protein results in increased reduction of 7-ketolithocholic acid] which results in increased chemical synthesis of Ursodeoxycholic Acid CTD PMID:21453287 HSD11B1 Human ursodeoxycholic acid increases abundance ISO Hsd11b1 (Mus musculus) 6480464 HSD11B1 gene mutant form results in increased abundance of Ursodeoxycholic Acid CTD PMID:25061560 HSD11B1 Human valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of HSD11B1 mRNA CTD PMID:28001369 HSD11B1 Human vinclozolin affects expression ISO Hsd11b1 (Rattus norvegicus) 6480464 vinclozolin affects the expression of HSD11B1 mRNA CTD PMID:19015723 HSD11B1 Human vitamin E increases expression EXP 6480464 Vitamin E results in increased expression of HSD11B1 mRNA CTD PMID:19244175 HSD11B1 Human zearalenone decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Zearalenone results in decreased expression of HSD11B1 mRNA and Zearalenone results in decreased expression of HSD11B1 protein CTD PMID:29669061 HSD11B1 Human zidovudine affects expression EXP 6480464 Zidovudine affects the expression of HSD11B1 mRNA CTD PMID:20032539 HSD11B1 Human zinc protoporphyrin multiple interactions ISO Hsd11b1 (Mus musculus) 6480464 zinc protoporphyrin inhibits the reaction [2-(3-benzoyl)-4-hydroxy-1 more ... CTD PMID:27523796 HSD11B1 Human zinc sulfate decreases expression EXP 6480464 Zinc Sulfate results in decreased expression of HSD11B1 mRNA CTD PMID:12756304 HSD11B1 Human ziram multiple interactions ISO Hsd11b1 (Rattus norvegicus) 6480464 Ziram inhibits the reaction [[HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] which results in increased chemical synthesis of Corticosterone] more ... CTD PMID:26859423 HSD11B1 Human ziram decreases activity ISO Hsd11b1 (Rattus norvegicus) 6480464 Ziram results in decreased activity of HSD11B1 protein CTD PMID:26859423 HSD11B1 Human ziram decreases expression ISO Hsd11b1 (Rattus norvegicus) 6480464 Ziram results in decreased expression of HSD11B1 mRNA and Ziram results in decreased expression of HSD11B1 protein CTD PMID:28973382 HSD11B1 Human zoledronic acid increases expression EXP 6480464 zoledronic acid results in increased expression of HSD11B1 mRNA CTD PMID:24714768