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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:corticosterone
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Accession:CHEBI:16827 term browser browse the term
Definition:A 21-hydroxy steroid that consists of pregn-4-ene substituted by hydroxy groups at positions 11 and 21 and oxo groups at positions 3 and 20. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
Synonyms:exact_synonym: 11beta,21-dihydroxypregn-4-ene-3,20-dione
 related_synonym: (11beta)-11,21-dihydroxypregn-4-ene-3,20-dione;   11beta,21-Dihydroxy-4-pregnene-3,20-dione;   11beta,21-dihydroxyprogesterone;   17-deoxycortisol;   Formula=C21H30O4;   InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1;   InChIKey=OMFXVFTZEKFJBZ-HJTSIMOOSA-N;   Kendall's compound B;   Reichstein's substance H;   SMILES=[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C)C(=O)CO
 alt_id: CHEBI:14022;   CHEBI:19131;   CHEBI:3891;   CHEBI:41361;   CHEBI:57911
 xref: Beilstein:2339601;   CAS:50-22-6;   HMDB:HMDB0001547;   KEGG:C02140;   LINCS:LSM-5814;   LIPID_MAPS_instance:LMST02030186
 xref_mesh: MESH:D003345
 xref: MetaCyc:CORTICOSTERONE;   PDBeChem:C0R;   PMID:10438974;   PMID:11448093;   PMID:16817814;   PMID:24446162;   Wikipedia:Corticosterone


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corticosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression EXP Corticosterone results in increased expression of A2M mRNA CTD PMID:15755911 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases activity ISO Corticosterone results in decreased activity of ABCG2 protein CTD PMID:15365089 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions EXP [Corticosterone co-treated with oleoyl-estrone] affects the expression of ACACA mRNA CTD PMID:19545626 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acan aggrecan decreases expression
multiple interactions		 EXP Corticosterone results in decreased expression of ACAN mRNA
Mifepristone inhibits the reaction [Corticosterone results in decreased expression of ACAN mRNA]		 CTD PMID:29660438 PMID:29966748 PMID:32663519 NCBI chr 1:132,981,034...133,044,416
Ensembl chr 1:132,981,582...133,043,627 		JBrowse link
G Ace angiotensin I converting enzyme increases expression
decreases methylation
multiple interactions		 EXP Corticosterone results in increased expression of ACE mRNA
Corticosterone results in decreased methylation of ACE promoter
Mifepristone inhibits the reaction [Corticosterone results in increased expression of ACE mRNA]		 CTD PMID:15755911 PMID:30423288 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ache acetylcholinesterase multiple interactions ISO [Corticosterone co-treated with Physostigmine] results in decreased activity of ACHE protein; ACHE protein inhibits the reaction [Paraoxon results in increased abundance of Corticosterone]; Corticosterone inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein]; Corticosterone inhibits the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased activity of ACHE protein] CTD PMID:17005312 PMID:28500787 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acly ATP citrate lyase multiple interactions EXP [Corticosterone co-treated with oleoyl-estrone] affects the expression of ACLY mRNA CTD PMID:19545626 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle increases expression EXP Corticosterone results in increased expression of ACTA1 mRNA CTD PMID:15755911 NCBI chr19:51,883,713...51,886,725
Ensembl chr19:51,883,715...51,886,742 		JBrowse link
G Actg2 actin gamma 2, smooth muscle increases expression EXP Corticosterone results in increased expression of ACTG2 mRNA CTD PMID:15755911 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression EXP Corticosterone results in increased expression of ADAMTS1 mRNA CTD PMID:15755911 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
increases expression		 ISO [Corticosterone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein
Corticosterone results in increased expression of ADIPOQ mRNA		 CTD PMID:29782964 PMID:34801515 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adm adrenomedullin increases expression EXP Corticosterone results in increased expression of ADM mRNA CTD PMID:15755911 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adora1 adenosine A1 receptor multiple interactions
decreases expression		 ISO Edaravone inhibits the reaction [Corticosterone results in decreased expression of ADORA1 mRNA] CTD PMID:31344373 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression EXP Corticosterone results in increased expression of ADRB2 mRNA CTD PMID:15755911 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Agt angiotensinogen increases secretion ISO AGT protein results in increased secretion of Corticosterone CTD PMID:28235592 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
decreases expression		 EXP Mifepristone inhibits the reaction [Corticosterone results in increased expression of AGTR1A mRNA]
Corticosterone results in decreased expression of AGTR1A mRNA		 CTD PMID:30423288 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions
decreases expression		 EXP Mifepristone inhibits the reaction [Corticosterone results in increased expression of AGTR2 mRNA]
Corticosterone results in decreased expression of AGTR2 mRNA		 CTD PMID:30423288 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 multiple interactions ISO [AKR1D1 protein co-treated with NADP] results in increased reduction of Corticosterone CTD PMID:25500266 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression EXP Corticosterone results in decreased expression of AKT1 mRNA CTD PMID:29966748 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 decreases expression EXP Corticosterone results in decreased expression of ALDH18A1 mRNA CTD PMID:15755911 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions
decreases expression		 EXP Enalapril inhibits the reaction [Corticosterone results in decreased expression of ALPL mRNA] CTD PMID:30423288 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression EXP Corticosterone results in decreased expression of ANGPTL2 mRNA CTD PMID:15755911 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178 		JBrowse link
G Aqp1 aquaporin 1 increases expression EXP Corticosterone results in increased expression of AQP1 mRNA CTD PMID:15755911 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Ar androgen receptor multiple interactions
affects binding
increases activity		 ISO
EXP		 [Testosterone co-treated with Estradiol co-treated with Corticosterone] promotes the reaction [AR protein binds to TRAF6 protein]; Corticosterone binds to and results in increased activity of AR protein mutant form; Corticosterone inhibits the reaction [Metribolone results in increased activity of AR protein]; Corticosterone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]
Corticosterone binds to AR protein
Corticosterone results in increased activity of AR protein		 CTD PMID:11956172 PMID:14565775 PMID:18324785 PMID:21543282 PMID:29162470 More... NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arrb1 arrestin, beta 1 decreases expression
multiple interactions		 ISO Corticosterone results in decreased expression of ARRB1 mRNA
Fluoxetine inhibits the reaction [Corticosterone results in decreased expression of ARRB1 mRNA]		 CTD PMID:19477151 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 decreases expression
multiple interactions		 ISO Corticosterone results in decreased expression of ARRB2 mRNA
Fluoxetine inhibits the reaction [Corticosterone results in decreased expression of ARRB2 mRNA]		 CTD PMID:19477151 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression EXP Corticosterone results in decreased expression of ASNS mRNA CTD PMID:15755911 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 decreases expression EXP Corticosterone results in decreased expression of ATP1A3 mRNA CTD PMID:15755911 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918 		JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 decreases expression EXP Corticosterone results in decreased expression of ATP6V1G1 mRNA CTD PMID:15755911 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463 		JBrowse link
G Aurkb aurora kinase B decreases expression EXP Corticosterone results in decreased expression of AURKB mRNA CTD PMID:15755911 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Avp arginine vasopressin decreases expression EXP Corticosterone results in decreased expression of AVP mRNA CTD PMID:32437893 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
affects expression		 EXP Corticosterone results in increased expression of BAX protein
Estradiol inhibits the reaction [Corticosterone results in increased expression of BAX protein]; Estradiol promotes the reaction [Testosterone inhibits the reaction [Corticosterone results in increased expression of BAX protein]]; so-ochim-tang-gamibang affects the reaction [Corticosterone affects the expression of BAX mRNA]; Testosterone inhibits the reaction [Corticosterone results in increased expression of BAX protein]; Testosterone promotes the reaction [Estradiol inhibits the reaction [Corticosterone results in increased expression of BAX protein]]		 CTD PMID:27988398 PMID:29625166 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
affects expression		 EXP Estradiol inhibits the reaction [Corticosterone results in decreased expression of BCL2 protein]; Estradiol promotes the reaction [Testosterone inhibits the reaction [Corticosterone results in decreased expression of BCL2 protein]]; so-ochim-tang-gamibang affects the reaction [Corticosterone affects the expression of BCL2 mRNA]; Testosterone inhibits the reaction [Corticosterone results in decreased expression of BCL2 protein]; Testosterone promotes the reaction [Estradiol inhibits the reaction [Corticosterone results in decreased expression of BCL2 protein]] CTD PMID:27988398 PMID:29625166 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression		 EXP [Corticosterone results in increased expression of BCL2L1 protein] which results in decreased susceptibility to Doxorubicin; BCL2L1 protein affects the reaction [Corticosterone results in decreased susceptibility to Doxorubicin]; JUN protein affects the reaction [Corticosterone results in increased expression of BCL2L1 mRNA]; Mifepristone inhibits the reaction [Corticosterone results in increased expression of BCL2L1 protein]
Corticosterone results in increased expression of BCL2L1 mRNA; Corticosterone results in increased expression of BCL2L1 protein		 CTD PMID:15755911 PMID:24480152 PMID:26915917 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
multiple interactions
affects expression		 ISO
EXP		 Corticosterone results in decreased expression of BDNF protein
2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in decreased expression of BDNF protein]; KT 5823 inhibits the reaction [2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in decreased expression of BDNF protein]]
Corticosterone results in decreased expression of BDNF mRNA
O-1602 compound affects the reaction [Corticosterone affects the expression of BDNF protein]; so-ochim-tang-gamibang inhibits the reaction [Corticosterone results in decreased expression of BDNF mRNA]		 CTD PMID:22244747 PMID:22850435 PMID:27988398 PMID:32733244 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bex1 brain expressed X-linked 1 decreases expression EXP Corticosterone results in decreased expression of BEX1 mRNA CTD PMID:15755911 NCBI chr  X:99,019,847...99,021,375
Ensembl chr  X:99,019,000...99,021,503 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression
multiple interactions		 EXP Corticosterone results in decreased expression of BGLAP mRNA
Enalapril inhibits the reaction [Corticosterone results in decreased expression of BGLAP mRNA]		 CTD PMID:30423288 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression EXP Corticosterone results in increased expression of BMP2 mRNA CTD PMID:15755911 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression EXP Corticosterone results in increased expression of BMP6 mRNA CTD PMID:15755911 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP Corticosterone results in increased expression of BTG2 mRNA CTD PMID:15755911 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G C3 complement C3 affects expression EXP Corticosterone affects the expression of C3 mRNA CTD PMID:18363858 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Calca calcitonin-related polypeptide alpha increases abundance
multiple interactions
increases expression		 EXP CALCA protein results in increased abundance of Corticosterone
O-1602 compound inhibits the reaction [Corticosterone results in increased expression of CALCA protein]		 CTD PMID:12639925 PMID:32733244 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Capn6 calpain 6 decreases expression EXP Corticosterone results in decreased expression of CAPN6 mRNA CTD PMID:15755911 NCBI chr  X:107,380,774...107,405,489
Ensembl chr  X:107,380,774...107,405,489 		JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 decreases expression EXP Corticosterone results in decreased expression of CARS mRNA CTD PMID:15755911 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941 		JBrowse link
G Cartpt CART prepropeptide increases abundance
multiple interactions		 EXP CARTPT protein results in increased abundance of Corticosterone
astressin B inhibits the reaction [CARTPT protein results in increased abundance of Corticosterone]		 CTD PMID:15271883 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Casp12 caspase 12 decreases expression EXP Corticosterone results in decreased expression of CASP12 mRNA CTD PMID:15755911 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases expression		 EXP Corticosterone inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein]; Corticosterone inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Corticosterone inhibits the reaction [Palmitates results in increased activity of CASP3 protein]; Estradiol inhibits the reaction [Corticosterone results in increased cleavage of CASP3 protein]; Estradiol promotes the reaction [Testosterone inhibits the reaction [Corticosterone results in increased cleavage of CASP3 protein]]; Mifepristone inhibits the reaction [Corticosterone inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]]; so-ochim-tang-gamibang inhibits the reaction [Corticosterone results in increased expression of CASP3 mRNA]; Testosterone inhibits the reaction [Corticosterone results in increased cleavage of CASP3 protein]; Testosterone promotes the reaction [Estradiol inhibits the reaction [Corticosterone results in increased cleavage of CASP3 protein]] CTD PMID:15755911 PMID:26915917 PMID:27988398 PMID:29625166 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 decreases expression EXP Corticosterone results in decreased expression of CASP4 mRNA CTD PMID:15755911 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage		 EXP Estradiol inhibits the reaction [Corticosterone results in increased cleavage of CASP8 protein]; Estradiol promotes the reaction [Testosterone inhibits the reaction [Corticosterone results in increased cleavage of CASP8 protein]]; Testosterone inhibits the reaction [Corticosterone results in increased cleavage of CASP8 protein]; Testosterone promotes the reaction [Estradiol inhibits the reaction [Corticosterone results in increased cleavage of CASP8 protein]] CTD PMID:29625166 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cat catalase increases activity
multiple interactions		 ISO Corticosterone results in increased activity of CAT protein
Clozapine inhibits the reaction [Corticosterone results in increased activity of CAT protein]; Clozapine inhibits the reaction [Lipopolysaccharides inhibits the reaction [Corticosterone results in increased activity of CAT protein]]; Lipopolysaccharides inhibits the reaction [Corticosterone results in increased activity of CAT protein]; Sulpiride promotes the reaction [Lipopolysaccharides inhibits the reaction [Corticosterone results in increased activity of CAT protein]]		 CTD PMID:14730115 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions		 EXP
ISO		 Corticosterone results in decreased expression of CCL2 mRNA
Corticosterone promotes the reaction [Isoflurophate results in increased expression of CCL2 mRNA]
[Corticosterone co-treated with Isoflurophate] results in increased expression of CCL2 mRNA; [Corticosterone co-treated with O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate] results in increased expression of CCL2 mRNA; [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CCL2 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CCL2 mRNA]; Corticosterone promotes the reaction [Isoflurophate results in increased expression of CCL2 mRNA]; Corticosterone promotes the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in increased expression of CCL2 mRNA]; Physostigmine inhibits the reaction [Corticosterone results in decreased expression of CCL2 mRNA]		 CTD PMID:15755911 PMID:28500787 PMID:28782715 PMID:29751049 PMID:29846716 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccn3 cellular communication network factor 3 increases expression EXP Corticosterone results in increased expression of CCN3 mRNA CTD PMID:15755911 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Ccnb1 cyclin B1 decreases expression EXP Corticosterone results in decreased expression of CCNB1 mRNA; Corticosterone results in decreased expression of CCNB1 protein CTD PMID:15755911 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Corticosterone results in decreased expression of CCND1 protein CTD PMID:12807724 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 decreases expression EXP Corticosterone results in decreased expression of CCND2 mRNA; Corticosterone results in decreased expression of CCND2 protein CTD PMID:15755911 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccne1 cyclin E1 decreases expression EXP Corticosterone results in decreased expression of CCNE1 protein CTD PMID:12807724 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Cd200 Cd200 molecule decreases expression EXP Corticosterone results in decreased expression of CD200 mRNA CTD PMID:15755911 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648 		JBrowse link
G Cd36 CD36 molecule increases expression EXP Corticosterone results in increased expression of CD36 mRNA CTD PMID:15755911 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd59b CD59b molecule increases expression EXP Corticosterone results in increased expression of CD59 mRNA CTD PMID:15755911 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CD68 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CD68 mRNA] CTD PMID:29751049 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP Corticosterone results in decreased expression of CDC20 mRNA CTD PMID:15755911 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO [Corticosterone results in increased phosphorylation of NDRG1 protein] which results in increased expression of and results in increased localization of CDH2 protein CTD PMID:21655274 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP Corticosterone results in decreased expression of CDK1 mRNA CTD PMID:15755911 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases activity
decreases expression		 EXP Corticosterone promotes the reaction [CDKN1A protein binds to CDK2 protein]
Corticosterone results in decreased activity of CDK2 protein
Corticosterone results in decreased expression of CDK2 protein		 CTD PMID:12807724 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions
decreases expression
decreases activity		 EXP Corticosterone inhibits the reaction [CDKN1A protein binds to CDK4 protein]; Corticosterone promotes the reaction [CDKN1B protein binds to CDK4 protein]
Corticosterone results in decreased expression of CDK4 protein
Corticosterone results in decreased activity of CDK4 protein		 CTD PMID:12807724 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A affects expression
multiple interactions		 EXP Corticosterone affects the expression of CDKN1A protein
Corticosterone inhibits the reaction [CDKN1A protein binds to CDK4 protein]; Corticosterone promotes the reaction [CDKN1A protein binds to CDK2 protein]		 CTD PMID:12807724 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression		 EXP Corticosterone promotes the reaction [CDKN1B protein binds to CDK4 protein]
Corticosterone results in increased expression of CDKN1B protein		 CTD PMID:12807724 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression EXP Corticosterone results in decreased expression of CDKN2A mRNA CTD PMID:15755911 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 increases expression EXP Corticosterone results in increased expression of CDO1 mRNA CTD PMID:15755911 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296 		JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 increases expression EXP Corticosterone results in increased expression of CEACAM10 mRNA CTD PMID:15755911 NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression EXP Corticosterone results in increased expression of CEBPA mRNA CTD PMID:30423288 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
multiple interactions		 EXP Corticosterone results in increased expression of CEBPB mRNA
CEBPB protein affects the reaction [Corticosterone results in increased expression of PTGS2 mRNA]; CEBPB protein affects the reaction [Corticosterone results in increased expression of PTGS2 protein]; Corticosterone promotes the reaction [CEBPB protein binds to PTGS2 promoter]		 CTD PMID:15755911 PMID:18650268 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression EXP
ISO		 Corticosterone results in increased expression of CEBPD mRNA CTD PMID:15755911 PMID:34801515 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Cfd complement factor D decreases expression ISO Corticosterone results in decreased expression of CFD mRNA; Corticosterone results in decreased expression of CFD protein CTD PMID:2912985 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP Corticosterone results in decreased expression of CKS2 mRNA CTD PMID:15755911 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn2 claudin 2 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CLDN2 protein CTD PMID:29751049 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Cnr1 cannabinoid receptor 1 increases abundance ISO CNR1 gene mutant form results in increased abundance of Corticosterone CTD PMID:15081793 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression
multiple interactions		 EXP Corticosterone results in decreased expression of COL2A1 mRNA; Corticosterone results in decreased expression of COL2A1 protein
Mifepristone inhibits the reaction [Corticosterone results in decreased expression of COL2A1 mRNA]		 CTD PMID:29660438 PMID:29966748 PMID:32663519 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions
decreases expression		 ISO Edaravone inhibits the reaction [Corticosterone results in decreased expression of COMT mRNA] CTD PMID:31344373 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cp ceruloplasmin increases expression EXP Corticosterone results in increased expression of CP mRNA CTD PMID:15755911 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Corticosterone results in increased expression of CPT1A mRNA CTD PMID:15755911 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases phosphorylation ISO Corticosterone results in decreased phosphorylation of CREB1 protein CTD PMID:22850435 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crebbp CREB binding protein multiple interactions
decreases expression		 ISO 2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in decreased expression of CREBBP protein]; KT 5823 inhibits the reaction [2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in decreased expression of CREBBP protein]] CTD PMID:22850435 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions
decreases expression
increases expression
affects expression
increases abundance		 EXP
ISO		 Astemizole inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]]; Corticosterone affects the reaction [Nitroprusside results in increased secretion of CRH protein]; Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]; E 4031 inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]]; O-1602 compound inhibits the reaction [Corticosterone results in increased expression of CRH protein]
CRH protein affects the reaction [[DUSP8 protein affects the susceptibility to Dietary Fats] which affects the abundance of Corticosterone]
Corticosterone results in decreased expression of CRH mRNA
Corticosterone results in increased expression of CRH mRNA; Corticosterone results in increased expression of CRH protein
Corticosterone affects the expression of CRH mRNA
CRH protein results in increased abundance of Corticosterone		 CTD PMID:3015567 PMID:7816204 PMID:18835572 PMID:21359208 PMID:26821211 More... NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 decreases expression EXP Corticosterone results in decreased expression of CRHR1 mRNA CTD PMID:18363858 NCBI chr10:89,040,203...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 increases expression EXP Corticosterone results in increased expression of CRISPLD2 mRNA CTD PMID:15755911 NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465 		JBrowse link
G Cs citrate synthase decreases activity EXP Corticosterone results in decreased activity of CS protein CTD PMID:22244747 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421 		JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 increases expression EXP Corticosterone results in increased expression of CSRP2 mRNA CTD PMID:15755911 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression EXP Corticosterone results in increased expression of CSRP3 mRNA CTD PMID:15755911 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Ctnna1 catenin alpha 1 multiple interactions ISO [Corticosterone results in increased phosphorylation of NDRG1 protein] which results in increased expression of and results in increased localization of CTNNA1 protein CTD PMID:21655274 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [Corticosterone results in increased phosphorylation of NDRG1 protein] promotes the reaction [NDRG1 protein binds to CTNNB1 protein]; [Corticosterone results in increased phosphorylation of NDRG1 protein] which results in increased expression of and results in increased localization of CTNNB1 protein CTD PMID:21655274 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctss cathepsin S increases expression EXP Corticosterone results in increased expression of CTSS mRNA CTD PMID:15755911 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 increases chemical synthesis ISO CYP11B1 protein results in increased chemical synthesis of Corticosterone CTD PMID:16054388 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 affects metabolic processing
multiple interactions
increases hydroxylation
increases chemical synthesis		 ISO CYP11B2 protein affects the metabolism of Corticosterone
[CYP11B2 protein results in increased hydroxylation of Corticosterone] which results in increased chemical synthesis of Aldosterone; [CYP11B2 protein results in increased hydroxylation of Desoxycorticosterone] which results in increased chemical synthesis of Corticosterone
CYP11B2 protein results in increased chemical synthesis of Corticosterone		 CTD PMID:16054388 PMID:21384875 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression		 EXP
ISO		 Corticosterone promotes the reaction [Ethanol results in increased expression of CYP1A2 mRNA]
Corticosterone results in increased expression of CYP1A2 mRNA		 CTD PMID:35301062 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 increases expression EXP Corticosterone results in increased expression of CYP2A2 mRNA CTD PMID:35301062 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression
multiple interactions		 EXP Corticosterone results in increased expression of CYP2B1 mRNA; Corticosterone results in increased expression of CYP2B1 protein
Corticosterone promotes the reaction [Ethanol results in increased expression of CYP2B1 protein]		 CTD PMID:35301062 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression		 ISO Corticosterone promotes the reaction [Ethanol results in increased expression of CYP2B6 mRNA]
Corticosterone results in increased expression of CYP2B6 mRNA; Corticosterone results in increased expression of CYP2B6 protein		 CTD PMID:35301062 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression EXP Corticosterone results in increased expression of CYP2C11 mRNA CTD PMID:35301062 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 increases expression EXP Corticosterone results in increased expression of CYP2D2 mRNA CTD PMID:35301062 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases expression
multiple interactions		 EXP
ISO		 Corticosterone results in increased expression of CYP2D4 mRNA
Corticosterone promotes the reaction [Ethanol results in increased expression of CYP2D6 mRNA]
Corticosterone results in increased expression of CYP2D6 mRNA		 CTD PMID:15755911 PMID:35301062 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression
multiple interactions		 ISO
EXP		 Corticosterone results in increased expression of CYP2E1 mRNA; Corticosterone results in increased expression of CYP2E1 protein
Corticosterone promotes the reaction [Ethanol results in increased expression of CYP2E1 mRNA]		 CTD PMID:35301062 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression		 ISO [Corticosterone binds to CYP3A4 promoter] which results in increased expression of CYP3A4 mRNA; Corticosterone promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Corticosterone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [Corticosterone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [Corticosterone results in increased expression of CYP3A4 mRNA]
Corticosterone results in increased expression of CYP3A4 mRNA; Corticosterone results in increased expression of CYP3A4 protein		 CTD PMID:11581012 PMID:12072427 PMID:12851153 PMID:35301062 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions
increases expression		 EXP Corticosterone promotes the reaction [Ethanol results in increased expression of CYP3A23-3A1 mRNA]
Corticosterone results in increased expression of CYP3A23-3A1 mRNA; Corticosterone results in increased expression of CYP3A23-3A1 protein		 CTD PMID:35301062 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Dbi diazepam binding inhibitor increases expression ISO Corticosterone results in increased expression of DBI mRNA CTD PMID:16963002 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase increases expression EXP Corticosterone results in increased expression of DCXR mRNA CTD PMID:15755911 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression EXP Corticosterone results in decreased expression of DDIT3 mRNA CTD PMID:15755911 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddt D-dopachrome tautomerase increases expression EXP Corticosterone results in increased expression of DDT mRNA CTD PMID:15755911 NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression
multiple interactions		 ISO Corticosterone results in increased expression of DKK1 protein
Mifepristone inhibits the reaction [Corticosterone results in increased expression of DKK1 protein]; NR3C1 protein promotes the reaction [Corticosterone results in increased expression of DKK1 protein]		 CTD PMID:21304589 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 decreases expression
multiple interactions		 ISO Corticosterone results in decreased expression of DLG4 protein
Ascorbic Acid inhibits the reaction [Corticosterone results in decreased expression of DLG4 protein]; Ketamine inhibits the reaction [Corticosterone results in decreased expression of DLG4 protein]		 CTD PMID:33872575 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression EXP Corticosterone results in decreased expression of DNMT3A mRNA CTD PMID:30423288 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dpep1 dipeptidase 1 increases expression EXP Corticosterone results in increased expression of DPEP1 mRNA CTD PMID:15755911 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257 		JBrowse link
G Dpt dermatopontin decreases expression EXP Corticosterone results in decreased expression of DPT mRNA CTD PMID:15755911 NCBI chr13:77,122,926...77,151,646
Ensembl chr13:77,123,115...77,151,639 		JBrowse link
G Dusp8 dual specificity phosphatase 8 multiple interactions ISO [DUSP8 protein affects the susceptibility to Dietary Fats] which affects the abundance of Corticosterone; CRH protein affects the reaction [[DUSP8 protein affects the susceptibility to Dietary Fats] which affects the abundance of Corticosterone]; Dexamethasone affects the reaction [[DUSP8 protein affects the susceptibility to Dietary Fats] which affects the abundance of Corticosterone] CTD PMID:32780722 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921 		JBrowse link
G Ecrg4 ECRG4 augurin precursor decreases expression EXP Corticosterone results in decreased expression of ECRG4 mRNA CTD PMID:15755911 NCBI chr 9:45,992,954...46,012,605
Ensembl chr 9:45,992,954...46,012,595 		JBrowse link
G Edn1 endothelin 1 increases secretion EXP EDN1 results in increased secretion of Corticosterone CTD PMID:1659878 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn2 endothelin 2 increases secretion EXP EDN2 results in increased secretion of Corticosterone CTD PMID:1659878 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G Edn3 endothelin 3 increases secretion EXP EDN3 results in increased secretion of Corticosterone CTD PMID:1659878 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093 		JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase increases expression EXP Corticosterone results in increased expression of EEF2K mRNA CTD PMID:15755911 NCBI chr 1:175,393,119...175,454,452
Ensembl chr 1:175,393,154...175,455,164 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 increases expression EXP Corticosterone results in increased expression of EFEMP1 mRNA CTD PMID:15755911 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression EXP Corticosterone results in increased expression of EGLN3 mRNA CTD PMID:15755911 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [Testosterone co-treated with Estradiol co-treated with Corticosterone] promotes the reaction [ESR1 protein binds to TRAF6 protein] CTD PMID:29625166 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression EXP Corticosterone results in decreased expression of EZH2 mRNA CTD PMID:15755911 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Faah fatty acid amide hydrolase increases activity
multiple interactions		 EXP Corticosterone results in increased activity of FAAH protein
antalarmin inhibits the reaction [Corticosterone results in increased activity of FAAH protein]		 CTD PMID:26821211 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677 		JBrowse link
G Fabp3 fatty acid binding protein 3 decreases expression EXP Corticosterone results in decreased expression of FABP3 mRNA CTD PMID:15755911 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [Corticosterone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein; Corticosterone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein] CTD PMID:29782964 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fabp7 fatty acid binding protein 7 affects expression EXP Corticosterone affects the expression of FABP7 mRNA CTD PMID:18363858 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880 		JBrowse link
G Fasn fatty acid synthase multiple interactions EXP [Corticosterone co-treated with oleoyl-estrone] affects the expression of FASN mRNA CTD PMID:19545626 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fbln2 fibulin 2 decreases expression EXP Corticosterone results in decreased expression of FBLN2 mRNA CTD PMID:15755911 NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948 		JBrowse link
G Fbn2 fibrillin 2 increases expression EXP Corticosterone results in increased expression of FBN2 mRNA CTD PMID:15755911 NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression
multiple interactions		 ISO Corticosterone results in decreased expression of FKBP5 mRNA
Edaravone inhibits the reaction [Corticosterone results in decreased expression of FKBP5 mRNA]		 CTD PMID:31344373 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression EXP Corticosterone results in increased expression of FLT1 mRNA CTD PMID:15755911 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 increases expression EXP Corticosterone results in increased expression of FMO1 mRNA CTD PMID:15755911 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Corticosterone results in increased expression of FOS protein CTD PMID:28186389 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxs1 forkhead box S1 decreases expression EXP Corticosterone results in decreased expression of FOXS1 mRNA CTD PMID:15755911 NCBI chr 3:141,397,012...141,398,281
Ensembl chr 3:141,397,016...141,398,281 		JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression ISO Corticosterone results in increased expression of FSHB mRNA CTD PMID:16675544 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Fstl3 follistatin like 3 increases expression EXP Corticosterone results in increased expression of FSTL3 mRNA CTD PMID:15755911 NCBI chr 7:9,924,670...9,929,195
Ensembl chr 7:9,923,576...9,939,639 		JBrowse link
G Fxyd6 FXYD domain-containing ion transport regulator 6 decreases expression EXP Corticosterone results in decreased expression of FXYD6 mRNA CTD PMID:15755911 NCBI chr 8:45,679,054...45,705,958
Ensembl chr 8:45,678,885...45,705,958 		JBrowse link
G G6pc2 glucose-6-phosphatase catalytic subunit 2 increases expression ISO Corticosterone results in increased expression of G6PC2 mRNA CTD PMID:27300767 NCBI chr 3:53,999,821...54,005,539 JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
increases expression		 ISO
EXP		 GAD1 affects the reaction [2,5-dihydro-2,4,5-trimethylthiazoline results in increased secretion of Corticosterone]
Corticosterone results in increased expression of GAD1 mRNA		 CTD PMID:21219938 PMID:32437893 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gal galanin and GMAP prepropeptide increases expression EXP Corticosterone results in increased expression of GAL mRNA CTD PMID:15755911 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Gas6 growth arrest specific 6 increases expression EXP Corticosterone results in increased expression of GAS6 mRNA CTD PMID:15755911 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gatm glycine amidinotransferase decreases expression EXP Corticosterone results in decreased expression of GATM mRNA CTD PMID:15755911 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129 		JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 increases expression EXP Corticosterone results in increased expression of GCNT1 mRNA CTD PMID:15755911 NCBI chr 1:214,718,344...214,755,735
Ensembl chr 1:214,718,293...214,758,776 		JBrowse link
G Gja5 gap junction protein, alpha 5 increases expression EXP Corticosterone results in increased expression of GJA5 mRNA CTD PMID:15755911 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Glt8d1 glycosyltransferase 8 domain containing 1 decreases expression EXP Corticosterone results in decreased expression of GLT8D1 mRNA CTD PMID:15755911 NCBI chr16:6,192,269...6,207,227
Ensembl chr16:6,192,300...6,207,229 		JBrowse link
G Glul glutamate-ammonia ligase increases expression EXP Corticosterone results in increased expression of GLUL mRNA CTD PMID:15755911 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression
multiple interactions		 ISO Corticosterone results in decreased expression of GNAI2 mRNA
Fluoxetine inhibits the reaction [Corticosterone results in decreased expression of GNAI2 mRNA]		 CTD PMID:19477151 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression EXP Corticosterone results in increased expression of GPX3 mRNA CTD PMID:15755911 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression ISO Corticosterone results in increased expression of GREB1 mRNA CTD PMID:35307500 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist decreases expression EXP Corticosterone results in decreased expression of GREM1 mRNA CTD PMID:15755911 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression
multiple interactions		 ISO Corticosterone results in decreased expression of GRIA1 protein
Ketamine inhibits the reaction [Corticosterone results in decreased expression of GRIA1 protein]		 CTD PMID:33872575 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 increases expression EXP Corticosterone results in increased expression of GRK5 mRNA CTD PMID:15755911 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP Corticosterone results in increased expression of GSTA3 mRNA; Corticosterone results in increased expression of GSTA3 protein CTD PMID:15755911 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression EXP Corticosterone results in increased expression of GSTM2 mRNA; Corticosterone results in increased expression of GSTM2 protein CTD PMID:15755911 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Hdac7 histone deacetylase 7 multiple interactions
increases expression		 EXP HDAC7 protein affects the reaction [Corticosterone results in decreased expression of KLF4 mRNA]; HDAC7 protein affects the reaction [Corticosterone results in decreased expression of KLF4 protein]; HDAC7 protein affects the reaction [Corticosterone results in decreased expression of NPHS1 mRNA]; HDAC7 protein affects the reaction [Corticosterone results in decreased expression of NPHS1 protein]; Mifepristone inhibits the reaction [Corticosterone results in increased expression of HDAC7 mRNA]; Mifepristone inhibits the reaction [Corticosterone results in increased expression of HDAC7 protein]
Corticosterone results in increased expression of HDAC7 mRNA; Corticosterone results in increased expression of HDAC7 protein		 CTD PMID:31306741 NCBI chr 7:128,923,918...128,962,025
Ensembl chr 7:128,923,920...128,962,072 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of HMGB1 protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of HMGB1 protein] CTD PMID:29751049 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565 		JBrowse link
G Hmgb2 high mobility group box 2 decreases expression EXP Corticosterone results in decreased expression of HMGB2 mRNA CTD PMID:15755911 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression EXP Corticosterone results in increased expression of HMGCS2 mRNA CTD PMID:15755911 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hmgn2 high mobility group nucleosomal binding domain 2 decreases expression EXP Corticosterone results in decreased expression of HMGN2 mRNA CTD PMID:15755911 NCBI chr 5:146,192,126...146,195,580
Ensembl chr 5:146,192,126...146,195,521 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 decreases expression EXP Corticosterone results in decreased expression of HNRNPA1 mRNA CTD PMID:15755911 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 increases expression EXP Corticosterone results in increased expression of HS3ST1 mRNA CTD PMID:15755911 NCBI chr14:71,185,826...71,223,263
Ensembl chr14:71,185,682...71,223,248 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases chemical synthesis
multiple interactions
increases oxidation
decreases abundance
increases expression		 ISO
EXP		 HSD11B1 protein results in increased chemical synthesis of Corticosterone
[[trimethyltin chloride results in increased abundance of trimethyltin] which co-treated with Corticosterone] results in increased expression of HSD11B1 mRNA; Corticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA]; Mifepristone inhibits the reaction [Corticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA]]; Spironolactone inhibits the reaction [Corticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA]]
HSD11B1 protein results in increased oxidation of Corticosterone
HSD11B1 gene mutant form results in decreased abundance of Corticosterone
[HSD11B1 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone; [HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] which results in increased chemical synthesis of Corticosterone; resveratrol inhibits the reaction [HSD11B1 protein results in increased chemical synthesis of Corticosterone]; Ziram inhibits the reaction [[HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] which results in increased chemical synthesis of Corticosterone]
Corticosterone results in increased expression of HSD11B1 mRNA		 CTD PMID:15755911 PMID:16751407 PMID:23814014 PMID:25061560 PMID:26859423 More... NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
increases oxidation
increases metabolic processing
affects metabolic processing		 EXP
ISO		 [HSD11B2 protein results in increased metabolism of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone; [HSD11B2 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone; Betamethasone inhibits the reaction [HSD11B2 protein affects the metabolism of Corticosterone]; Dexamethasone inhibits the reaction [HSD11B2 protein affects the metabolism of Corticosterone]; Ziram inhibits the reaction [[HSD11B2 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone]; Ziram inhibits the reaction [HSD11B2 protein results in increased oxidation of Corticosterone] CTD PMID:19490994 PMID:22796344 PMID:26859423 PMID:32243540 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP Corticosterone results in increased expression of HSPB1 mRNA; Corticosterone results in increased expression of HSPB1 protein CTD PMID:15755911 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspb6 heat shock protein family B (small) member 6 increases expression EXP Corticosterone results in increased expression of HSPB6 mRNA CTD PMID:15755911 NCBI chr 1:85,806,898...85,809,072
Ensembl chr 1:85,806,146...85,809,071 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
increases secretion
increases expression		 EXP [alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of JAK2 protein] inhibits the reaction [HTR2A protein results in increased secretion of Corticosterone]; [Ketanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [Methamphetamine results in increased secretion of Corticosterone]
Corticosterone results in increased expression of HTR2A mRNA		 CTD PMID:15755911 PMID:18363858 PMID:19304867 PMID:19879056 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Ier3 immediate early response 3 decreases expression EXP Corticosterone results in decreased expression of IER3 mRNA CTD PMID:15755911 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression
multiple interactions
increases expression		 EXP Corticosterone results in decreased expression of IGF1 mRNA; Corticosterone results in decreased expression of IGF1 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide inhibits the reaction [IGF1 protein inhibits the reaction [Corticosterone results in decreased expression of IGF1 mRNA]]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide inhibits the reaction [IGF1 protein inhibits the reaction [Corticosterone results in decreased expression of PCNA mRNA]]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide inhibits the reaction [IGF1 protein inhibits the reaction [Corticosterone results in decreased phosphorylation of MAPK1 protein]]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide inhibits the reaction [IGF1 protein inhibits the reaction [Corticosterone results in decreased phosphorylation of MAPK3 protein]]; IGF1 protein inhibits the reaction [Corticosterone results in decreased expression of IGF1 mRNA]; IGF1 protein inhibits the reaction [Corticosterone results in decreased expression of PCNA mRNA]; IGF1 protein inhibits the reaction [Corticosterone results in decreased phosphorylation of MAPK1 protein]; IGF1 protein inhibits the reaction [Corticosterone results in decreased phosphorylation of MAPK3 protein]
Corticosterone results in increased expression of IGF1 mRNA		 CTD PMID:12807724 PMID:15755911 PMID:29343424 PMID:29966748 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression
multiple interactions		 EXP Corticosterone results in decreased expression of IGF1R mRNA; Corticosterone results in decreased expression of IGF1R protein
[IGF2R protein co-treated with IGF1R protein] affects the reaction [IGF2 protein inhibits the reaction [Corticosterone results in decreased expression of SOD2 protein]]		 CTD PMID:12807724 PMID:24667322 PMID:29966748 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions EXP [IGF2R protein co-treated with IGF1R protein] affects the reaction [IGF2 protein inhibits the reaction [Corticosterone results in decreased expression of SOD2 protein]]; IGF2 protein inhibits the reaction [Corticosterone results in decreased expression of SOD2 protein] CTD PMID:24667322 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor multiple interactions EXP [IGF2R protein co-treated with IGF1R protein] affects the reaction [IGF2 protein inhibits the reaction [Corticosterone results in decreased expression of SOD2 protein]] CTD PMID:24667322 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression EXP Corticosterone results in decreased expression of IGFBP5 mRNA CTD PMID:15755911 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 increases expression EXP Corticosterone results in increased expression of IGFBP6 mRNA CTD PMID:15755911 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966 		JBrowse link
G Il15 interleukin 15 increases expression EXP Corticosterone results in increased expression of IL15 mRNA CTD PMID:15755911 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il1b interleukin 1 beta increases chemical synthesis
increases expression
affects expression
multiple interactions
increases secretion		 ISO
EXP		 IL1B protein results in increased chemical synthesis of Corticosterone
Corticosterone results in increased expression of IL1B mRNA
Corticosterone affects the expression of IL1B mRNA
Corticosterone results in increased expression of IL1B mRNA; Corticosterone results in increased expression of IL1B protein
[Corticosterone co-treated with Isoflurophate] results in increased expression of IL1B mRNA; [Corticosterone co-treated with O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate] results in increased expression of IL1B mRNA; [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of and results in increased secretion of IL1B protein; [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of IL1B mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of and results in increased secretion of IL1B protein]; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of IL1B mRNA]; O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate affects the reaction [Corticosterone affects the expression of IL1B mRNA]; Physostigmine affects the reaction [Corticosterone affects the expression of IL1B mRNA]
Corticosterone promotes the reaction [Isoflurophate results in increased expression of IL1B mRNA]; Ketorolac inhibits the reaction [IL1B protein results in increased secretion of Corticosterone]; O-1602 compound inhibits the reaction [Corticosterone results in increased expression of IL1B protein]
[Finasteride results in increased susceptibility to IL1B protein] which results in increased secretion of Corticosterone		 CTD PMID:10800959 PMID:12773775 PMID:19458216 PMID:28500787 PMID:28782715 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression EXP Corticosterone results in decreased expression of IL1RL1 mRNA CTD PMID:15755911 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
increases expression		 EXP
ISO		 Corticosterone inhibits the reaction [Isoflurophate results in increased expression of IL6 mRNA]
Corticosterone results in decreased expression of IL6 mRNA
[Corticosterone co-treated with Physostigmine] results in decreased expression of IL6 mRNA; [Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of IL6 mRNA; Corticosterone inhibits the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased expression of IL6 mRNA]; Corticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of IL6 mRNA]; Isoflurophate inhibits the reaction [Corticosterone results in decreased expression of IL6 mRNA]; O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate inhibits the reaction [Corticosterone results in decreased expression of IL6 mRNA]; Spironolactone inhibits the reaction [Corticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of IL6 mRNA]]
Corticosterone results in increased expression of IL6 mRNA		 CTD PMID:28500787 PMID:28782715 PMID:29846716 PMID:30993381 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO [Corticosterone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein; [Corticosterone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein; Corticosterone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein] CTD PMID:29782964 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Itga1 integrin subunit alpha 1 decreases expression EXP Corticosterone results in decreased expression of ITGA1 mRNA CTD PMID:15755911 NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238 		JBrowse link
G Itga8 integrin subunit alpha 8 increases expression EXP Corticosterone results in increased expression of ITGA8 mRNA CTD PMID:15755911 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510 		JBrowse link
G Itgb1bp2 integrin subunit beta 1 binding protein 2 increases expression EXP Corticosterone results in increased expression of ITGB1BP2 mRNA CTD PMID:15755911 NCBI chr  X:66,572,537...66,577,174
Ensembl chr  X:66,572,537...66,577,174 		JBrowse link
G Jak2 Janus kinase 2 multiple interactions EXP [alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of JAK2 protein] inhibits the reaction [HTR2A protein results in increased secretion of Corticosterone] CTD PMID:19304867 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP JUN protein affects the reaction [Corticosterone results in increased expression of BCL2L1 mRNA] CTD PMID:26915917 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 increases expression EXP Corticosterone results in increased expression of KCNH2 mRNA CTD PMID:18835572 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 increases expression EXP Corticosterone results in increased expression of KCNJ5 mRNA CTD PMID:15755911 NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518 		JBrowse link
G Kdr kinase insert domain receptor multiple interactions
decreases expression		 ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Corticosterone results in decreased expression of KDR protein]; Calcium promotes the reaction [Corticosterone results in decreased expression of KDR protein]; Corticosterone inhibits the reaction [KDR protein binds to NR3C1 protein]; Mifepristone inhibits the reaction [Corticosterone results in decreased expression of KDR protein]; NR3C1 protein promotes the reaction [Corticosterone results in decreased expression of KDR protein] CTD PMID:21647420 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kif15 kinesin family member 15 decreases expression EXP Corticosterone results in decreased expression of KIF15 mRNA CTD PMID:15755911 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750 		JBrowse link
G Kifc1 kinesin family member C1 decreases expression EXP Corticosterone results in decreased expression of KIFC1 mRNA CTD PMID:15755911 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions
decreases expression		 EXP HDAC7 protein affects the reaction [Corticosterone results in decreased expression of KLF4 mRNA]; HDAC7 protein affects the reaction [Corticosterone results in decreased expression of KLF4 protein]; KLF4 protein inhibits the reaction [Corticosterone results in decreased expression of NPHS1 mRNA]; KLF4 protein inhibits the reaction [Corticosterone results in decreased expression of NPHS1 protein]; Mifepristone inhibits the reaction [Corticosterone results in decreased expression of KLF4 mRNA]; Mifepristone inhibits the reaction [Corticosterone results in decreased expression of KLF4 protein]; trichostatin A inhibits the reaction [Corticosterone results in decreased expression of KLF4 mRNA]; trichostatin A inhibits the reaction [Corticosterone results in decreased expression of KLF4 protein]
Corticosterone results in decreased expression of KLF4 mRNA; Corticosterone results in decreased expression of KLF4 protein		 CTD PMID:31306741 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klf9 KLF transcription factor 9 increases expression EXP Corticosterone results in increased expression of KLF9 mRNA CTD PMID:15755911 NCBI chr 1:220,700,108...220,725,029
Ensembl chr 1:220,700,108...220,725,037 		JBrowse link
G Lep leptin multiple interactions
decreases expression		 ISO 1-(3-chlorophenyl)piperazine inhibits the reaction [Corticosterone results in decreased expression of LEP protein]; 8-(5-(5-amino-2,4-dimethoxyphenyl)-5-oxopentyl)-1,3,8-triazaspiro(4.5)decane-2,4-dione inhibits the reaction [1-(3-chlorophenyl)piperazine inhibits the reaction [Corticosterone results in decreased expression of LEP protein]]; [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of LEP protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of LEP protein] CTD PMID:28186389 PMID:29751049 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions
decreases expression		 EXP
ISO		 [Corticosterone co-treated with Isoflurophate] results in increased expression of LIF mRNA
[Corticosterone co-treated with Isoflurophate] results in increased expression of LIF mRNA; [Corticosterone co-treated with O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate] results in increased expression of LIF mRNA; [Corticosterone co-treated with Physostigmine] results in decreased expression of LIF mRNA
Corticosterone results in decreased expression of LIF mRNA		 CTD PMID:28500787 PMID:28782715 PMID:29846716 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lmnb1 lamin B1 decreases expression EXP Corticosterone results in decreased expression of LMNB1 mRNA CTD PMID:15755911 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 increases expression EXP Corticosterone results in increased expression of LPAR1 mRNA CTD PMID:15755911 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 multiple interactions
increases secretion		 ISO LRRK2 protein mutant form promotes the reaction [Paraquat results in increased secretion of Corticosterone]
LRRK2 protein mutant form results in increased secretion of Corticosterone; LRRK2 protein results in increased secretion of Corticosterone		 CTD PMID:31174552 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Maged2 MAGE family member D2 decreases expression EXP Corticosterone results in decreased expression of MAGED2 mRNA CTD PMID:15755911 NCBI chr  X:19,733,593...19,741,769
Ensembl chr  X:19,733,597...19,740,477 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 multiple interactions
increases phosphorylation		 EXP 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [Estradiol inhibits the reaction [Corticosterone results in increased phosphorylation of MAP3K7 protein]]; Estradiol inhibits the reaction [Corticosterone results in increased phosphorylation of MAP3K7 protein]; Flutamide inhibits the reaction [Estradiol inhibits the reaction [Corticosterone results in increased phosphorylation of MAP3K7 protein]]; Testosterone promotes the reaction [Estradiol inhibits the reaction [Corticosterone results in increased phosphorylation of MAP3K7 protein]] CTD PMID:29625166 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
decreases phosphorylation
multiple interactions
decreases activity		 EXP
ISO		 Corticosterone results in increased phosphorylation of MAPK1 protein
Corticosterone results in decreased phosphorylation of MAPK1 protein
2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in increased phosphorylation of MAPK1 protein]; KT 5823 inhibits the reaction [2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in increased phosphorylation of MAPK1 protein]]
Corticosterone results in decreased activity of MAPK1 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide inhibits the reaction [IGF1 protein inhibits the reaction [Corticosterone results in decreased phosphorylation of MAPK1 protein]]; Curcumin inhibits the reaction [Corticosterone results in increased phosphorylation of MAPK1 protein]; IGF1 protein inhibits the reaction [Corticosterone results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:19175364 PMID:19733225 PMID:22850435 PMID:29343424 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
decreases phosphorylation
multiple interactions
decreases activity		 EXP
ISO		 Corticosterone results in increased phosphorylation of MAPK3 protein
Corticosterone results in decreased phosphorylation of MAPK3 protein
2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in increased phosphorylation of MAPK3 protein]; KT 5823 inhibits the reaction [2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one inhibits the reaction [Corticosterone results in increased phosphorylation of MAPK3 protein]]
Corticosterone results in decreased activity of MAPK3 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide inhibits the reaction [IGF1 protein inhibits the reaction [Corticosterone results in decreased phosphorylation of MAPK3 protein]]; Curcumin inhibits the reaction [Corticosterone results in increased phosphorylation of MAPK3 protein]; IGF1 protein inhibits the reaction [Corticosterone results in decreased phosphorylation of MAPK3 protein]		 CTD PMID:19175364 PMID:19733225 PMID:22850435 PMID:29343424 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mb myoglobin decreases expression EXP Corticosterone results in decreased expression of MB mRNA CTD PMID:15755911 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mc2r melanocortin 2 receptor multiple interactions
increases secretion		 EXP MC2R protein promotes the reaction [PRL protein results in increased secretion of Corticosterone]; PRL protein promotes the reaction [MC2R protein results in increased secretion of Corticosterone] CTD PMID:18609294 NCBI chr18:62,001,980...62,015,567
Ensembl chr18:62,004,948...62,015,488 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression EXP Corticosterone results in decreased expression of MCM3 mRNA CTD PMID:15755911 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression EXP Corticosterone results in decreased expression of MCM4 mRNA CTD PMID:15755911 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 decreases expression EXP Corticosterone results in decreased expression of MCM6 mRNA CTD PMID:15755911 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression EXP Corticosterone results in decreased expression of MCM7 mRNA CTD PMID:15755911 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063 		JBrowse link
G Me1 malic enzyme 1 decreases expression EXP Corticosterone results in decreased expression of ME1 mRNA CTD PMID:15755911 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Melk maternal embryonic leucine zipper kinase decreases expression EXP Corticosterone results in decreased expression of MELK mRNA CTD PMID:15755911 NCBI chr 5:58,540,393...58,600,937
Ensembl chr 5:58,540,449...58,600,937 		JBrowse link
G Mfn1 mitofusin 1 decreases expression EXP Corticosterone results in decreased expression of MFN1 mRNA CTD PMID:22244747 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mfn2 mitofusin 2 decreases expression EXP Corticosterone results in decreased expression of MFN2 mRNA CTD PMID:22244747 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 increases expression EXP Corticosterone results in increased expression of MGST2 mRNA CTD PMID:15755911 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828 		JBrowse link
G Mmp12 matrix metallopeptidase 12 decreases expression EXP Corticosterone results in decreased expression of MMP12 mRNA CTD PMID:15755911 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mt1 metallothionein 1 increases expression EXP Corticosterone results in increased expression of MT1A mRNA CTD PMID:15755911 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO Corticosterone results in decreased phosphorylation of MTOR protein CTD PMID:21647420 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 increases expression EXP Corticosterone results in increased expression of MUSTN1 mRNA CTD PMID:15755911 NCBI chr16:6,072,908...6,075,158
Ensembl chr16:6,072,833...6,075,161 		JBrowse link
G Myh11 myosin heavy chain 11 increases expression EXP Corticosterone results in increased expression of MYH11 mRNA CTD PMID:15755911 NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459 		JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 decreases expression EXP Corticosterone results in decreased expression of NCAPD2 mRNA CTD PMID:15755911 NCBI chr 4:157,968,814...157,992,314
Ensembl chr 4:157,968,815...157,992,020 		JBrowse link
G Ncaph2 non-SMC condensin II complex, subunit H2 decreases expression EXP Corticosterone results in decreased expression of NCAPH2 mRNA CTD PMID:15755911 NCBI chr 7:120,422,926...120,439,942
Ensembl chr 7:120,422,956...120,439,938 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Corticosterone promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:11581012 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Ncs1 neuronal calcium sensor 1 increases expression ISO Corticosterone results in increased expression of NCS1 protein CTD PMID:21647420 NCBI chr 3:14,523,220...14,568,829
Ensembl chr 3:14,523,220...14,568,829 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions
increases phosphorylation		 ISO [Corticosterone results in increased phosphorylation of NDRG1 protein] promotes the reaction [NDRG1 protein binds to CTNNB1 protein]; [Corticosterone results in increased phosphorylation of NDRG1 protein] which results in increased expression of and results in increased localization of CDH2 protein; [Corticosterone results in increased phosphorylation of NDRG1 protein] which results in increased expression of and results in increased localization of CTNNA1 protein; [Corticosterone results in increased phosphorylation of NDRG1 protein] which results in increased expression of and results in increased localization of CTNNB1 protein
[Corticosterone results in increased phosphorylation of SGK1 protein] which results in increased phosphorylation of NDRG1 protein		 CTD PMID:21655274 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Ndrg2 NDRG family member 2 increases expression EXP Corticosterone results in increased expression of NDRG2 mRNA CTD PMID:15755911 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression EXP Corticosterone results in increased expression of NFKBIA mRNA CTD PMID:15755911 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ngf nerve growth factor decreases expression
multiple interactions		 EXP Corticosterone results in decreased expression of NGF protein
O-1602 compound inhibits the reaction [Corticosterone results in decreased expression of NGF protein]		 CTD PMID:32733244 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nppa natriuretic peptide A increases expression
multiple interactions		 EXP Corticosterone results in increased expression of NPPA mRNA
Corticosterone promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]		 CTD PMID:16533503 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Npy neuropeptide Y decreases expression EXP Corticosterone results in decreased expression of NPY mRNA CTD PMID:15755911 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Corticosterone binds to and results in increased activity of NR1I2 protein; Corticosterone promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Corticosterone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [Corticosterone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]] CTD PMID:11581012 PMID:12072427 PMID:16054614 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO Corticosterone binds to and results in increased activity of NR1I3 protein; Corticosterone inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein] CTD PMID:18832183 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
affects binding
increases activity
affects abundance
decreases expression
affects localization
increases expression		 ISO
EXP		 Corticosterone binds to and results in increased activity of NR3C1 protein
Corticosterone binds to NR3C1 protein
Corticosterone results in increased activity of NR3C1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Carbamazepine inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Lithium inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Valproic Acid inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]]; Carbamazepine inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]; Chlorpromazine inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]; Clozapine inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]; Corticosterone inhibits the reaction [KDR protein binds to NR3C1 protein]; Lithium inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]; Mifepristone inhibits the reaction [Corticosterone results in decreased expression of NR3C1 protein]; Mifepristone inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]; NR3C1 protein promotes the reaction [Corticosterone results in decreased expression of KDR protein]; NR3C1 protein promotes the reaction [Corticosterone results in increased expression of DKK1 protein]; Pregnanolone analog inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]; Pregnanolone inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]; pyrazolanthrone inhibits the reaction [Valproic Acid inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]]; Valproic Acid inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]
NR3C1 protein affects the abundance of Corticosterone
[Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [Corticosterone results in increased expression of PTGS2 mRNA]; [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [Corticosterone results in increased expression of PTGS2 protein]; Corticosterone promotes the reaction [[NR3C1 protein binds to TAT promoter] which results in increased expression of TAT mRNA]; Corticosterone promotes the reaction [NR3C1 protein binds to PTGS2 promoter]; Lead inhibits the reaction [Corticosterone binds to NR3C1 protein]; Mifepristone inhibits the reaction [Corticosterone promotes the reaction [NR3C1 protein binds to PTGS2 promoter]]
Corticosterone affects the localization of NR3C1 protein
Corticosterone results in increased expression of NR3C1 mRNA
Corticosterone results in increased expression of NR3C1 mRNA; Corticosterone results in increased expression of NR3C1 protein		 CTD PMID:10509797 PMID:11861974 PMID:15249158 PMID:15705660 PMID:16049266 More... NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 affects binding ISO Corticosterone binds to NR3C2 protein CTD PMID:16061183 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 increases expression EXP Corticosterone results in increased expression of NTRK3 mRNA CTD PMID:18363858 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Ocln occludin multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of OCLN protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of OCLN protein] CTD PMID:29751049 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Omd osteomodulin increases expression EXP Corticosterone results in increased expression of OMD mRNA CTD PMID:15755911 NCBI chr17:15,060,217...15,068,441
Ensembl chr17:15,060,217...15,068,441 		JBrowse link
G Oplah 5-oxoprolinase (ATP-hydrolysing) increases expression EXP Corticosterone results in increased expression of OPLAH mRNA CTD PMID:15755911 NCBI chr 7:108,011,472...108,051,751
Ensembl chr 7:108,011,475...108,035,297 		JBrowse link
G Orm1 orosomucoid 1 increases expression EXP Corticosterone results in increased expression of ORM1 mRNA CTD PMID:15755911 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G Osm oncostatin M multiple interactions EXP
ISO		 [Corticosterone co-treated with Isoflurophate] results in increased expression of OSM mRNA
[Corticosterone co-treated with Isoflurophate] results in increased expression of OSM mRNA; [Corticosterone co-treated with Physostigmine] results in increased expression of OSM mRNA; Corticosterone promotes the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in increased expression of OSM mRNA]		 CTD PMID:28500787 PMID:28782715 PMID:29846716 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313 		JBrowse link
G P3h1 prolyl 3-hydroxylase 1 decreases expression EXP Corticosterone results in decreased expression of P3H1 mRNA CTD PMID:15755911 NCBI chr 5:132,841,868...132,856,664
Ensembl chr 5:132,841,928...132,856,659 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) decreases expression EXP Corticosterone results in decreased expression of PCK2 mRNA CTD PMID:15755911 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression
multiple interactions		 EXP Corticosterone results in decreased expression of PCNA mRNA; Corticosterone results in decreased expression of PCNA protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide inhibits the reaction [IGF1 protein inhibits the reaction [Corticosterone results in decreased expression of PCNA mRNA]]; IGF1 protein inhibits the reaction [Corticosterone results in decreased expression of PCNA mRNA]		 CTD PMID:15755911 PMID:29343424 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pde2a phosphodiesterase 2A increases expression
multiple interactions		 ISO
EXP		 Corticosterone results in increased expression of PDE2A mRNA; Corticosterone results in increased expression of PDE2A mRNA alternative form; Corticosterone results in increased expression of PDE2A protein
Mifepristone inhibits the reaction [Corticosterone results in increased expression of PDE2A protein]		 CTD PMID:22850435 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO [Corticosterone results in increased phosphorylation of and results in increased activity of PDK1 protein] which results in increased phosphorylation of and results in increased activity of SGK1 protein; Corticosterone results in increased phosphorylation of and results in increased activity of PDK1 protein CTD PMID:21655274 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 increases expression EXP Corticosterone results in increased expression of PDLIM5 mRNA CTD PMID:15755911 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275 		JBrowse link
G Pdlim7 PDZ and LIM domain 7 increases expression EXP Corticosterone results in increased expression of PDLIM7 mRNA CTD PMID:15755911 NCBI chr17:9,124,565...9,139,814
Ensembl chr17:9,124,649...9,139,811 		JBrowse link
G Pdyn prodynorphin multiple interactions EXP
ISO		 Corticosterone inhibits the reaction [[Oxidopamine co-treated with Levodopa] results in increased expression of PDYN mRNA]
PDYN protein promotes the reaction [Cocaine results in increased abundance of Corticosterone]		 CTD PMID:17532787 PMID:18687386 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Penk proenkephalin multiple interactions EXP Corticosterone inhibits the reaction [[Oxidopamine co-treated with Levodopa] results in increased expression of PENK mRNA] CTD PMID:18687386 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Pfkl phosphofructokinase, liver type increases expression EXP Corticosterone results in increased expression of PFKL mRNA CTD PMID:15755911 NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315 		JBrowse link
G Pfkp phosphofructokinase, platelet multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA] CTD PMID:29751049 NCBI chr17:63,729,743...63,794,021
Ensembl chr17:63,729,780...63,794,018 		JBrowse link
G Pfn2 profilin 2 decreases expression EXP Corticosterone results in decreased expression of PFN2 mRNA CTD PMID:15755911 NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938 		JBrowse link
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase increases expression EXP Corticosterone results in increased expression of PIM3 mRNA CTD PMID:15755911 NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587 		JBrowse link
G Pla1a phospholipase A1 member A increases expression EXP Corticosterone results in increased expression of PLA1A mRNA CTD PMID:15755911 NCBI chr11:62,320,117...62,357,779
Ensembl chr11:62,320,493...62,357,779 		JBrowse link
G Plk1 polo-like kinase 1 decreases expression EXP Corticosterone results in decreased expression of PLK1 mRNA CTD PMID:15755911 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Plk2 polo-like kinase 2 decreases expression EXP Corticosterone results in decreased expression of PLK2 mRNA CTD PMID:15755911 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Plk4 polo-like kinase 4 decreases expression EXP Corticosterone results in decreased expression of PLK4 mRNA CTD PMID:15755911 NCBI chr 2:123,802,512...123,820,942
Ensembl chr 2:123,802,512...123,820,942 		JBrowse link
G Podxl podocalyxin-like increases expression EXP Corticosterone results in increased expression of PODXL mRNA CTD PMID:15755911 NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899 		JBrowse link
G Pomc proopiomelanocortin multiple interactions
increases secretion
increases abundance
decreases abundance
decreases secretion		 EXP
ISO		 Bromocriptine inhibits the reaction [POMC protein results in decreased secretion of Corticosterone]; Corticosterone inhibits the reaction [Nitroprusside results in increased secretion of POMC protein]; Cromolyn Sodium inhibits the reaction [POMC results in increased secretion of Corticosterone]; Fulvestrant inhibits the reaction [nonylphenol promotes the reaction [POMC protein modified form results in increased secretion of Corticosterone]]; Nitroprusside inhibits the reaction [POMC protein modified form results in increased secretion of Corticosterone]; nonylphenol inhibits the reaction [Nitroprusside inhibits the reaction [POMC protein modified form results in increased secretion of Corticosterone]]; nonylphenol promotes the reaction [POMC protein modified form results in increased secretion of Corticosterone]; oxophenylarsine inhibits the reaction [POMC protein results in increased abundance of Corticosterone]; pervanadate inhibits the reaction [POMC protein results in increased abundance of Corticosterone]; SB 203580 inhibits the reaction [POMC protein modified form results in increased secretion of Corticosterone]
lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [POMC protein modified form results in increased secretion of Corticosterone]; resveratrol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [POMC protein modified form results in increased secretion of Corticosterone]]
POMC protein results in decreased abundance of Corticosterone
POMC protein modified form results in increased secretion of Corticosterone; POMC protein results in increased secretion of Corticosterone; POMC results in increased secretion of Corticosterone
Corticosterone results in decreased secretion of POMC protein; POMC protein results in decreased secretion of Corticosterone		 CTD PMID:1659878 PMID:3015567 PMID:7588239 PMID:10518784 PMID:11132610 More... NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA] CTD PMID:29751049 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of PPARG mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of PPARG mRNA] CTD PMID:29751049 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B multiple interactions ISO Cocaine promotes the reaction [PPP1R1B protein results in increased abundance of Corticosterone] CTD PMID:10516482 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression EXP Corticosterone results in decreased expression of PPP2R2B mRNA CTD PMID:15755911 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025 		JBrowse link
G Prim1 DNA primase subunit 1 decreases expression EXP Corticosterone results in decreased expression of PRIM1 mRNA CTD PMID:15755911 NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha multiple interactions ISO [Androgens deficiency affects the activity of PRKAR1A gene mutant form] which results in increased secretion of Corticosterone; [PRKAR1A gene mutant form results in increased susceptibility to Androgens deficiency] which results in increased secretion of Corticosterone; Dexamethasone inhibits the reaction [[PRKAR1A gene mutant form results in increased susceptibility to Androgens deficiency] which results in increased secretion of Corticosterone]; Dexamethasone inhibits the reaction [PRKAR1A gene mutant form results in increased secretion of Corticosterone]; Dihydrotestosterone inhibits the reaction [[Androgens deficiency affects the activity of PRKAR1A gene mutant form] which results in increased secretion of Corticosterone]; Dihydrotestosterone inhibits the reaction [[PRKAR1A gene mutant form results in increased susceptibility to Androgens deficiency] which results in increased secretion of Corticosterone] CTD PMID:29367455 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione promotes the reaction [Corticosterone results in increased activity of PRKCA protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Corticosterone results in increased activity of PRKCA protein] CTD PMID:16581232 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prl prolactin multiple interactions EXP MC2R protein promotes the reaction [PRL protein results in increased secretion of Corticosterone]; PRL protein promotes the reaction [MC2R protein results in increased secretion of Corticosterone] CTD PMID:18609294 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Pten phosphatase and tensin homolog increases phosphorylation ISO Corticosterone results in increased phosphorylation of PTEN protein CTD PMID:21647420 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgds prostaglandin D2 synthase increases expression EXP Corticosterone results in increased expression of PTGDS mRNA CTD PMID:15755911 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases expression EXP Corticosterone results in increased expression of PTGS1 mRNA; Corticosterone results in increased expression of PTGS1 protein CTD PMID:15755911 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 EXP [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [Corticosterone results in increased expression of PTGS2 mRNA]; [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [Corticosterone results in increased expression of PTGS2 protein]; CEBPB protein affects the reaction [Corticosterone results in increased expression of PTGS2 mRNA]; CEBPB protein affects the reaction [Corticosterone results in increased expression of PTGS2 protein]; Corticosterone promotes the reaction [CEBPB protein binds to PTGS2 promoter]; Corticosterone promotes the reaction [NR3C1 protein binds to PTGS2 promoter]; Dactinomycin inhibits the reaction [Corticosterone results in increased expression of PTGS2 mRNA]; Dactinomycin inhibits the reaction [Corticosterone results in increased expression of PTGS2 protein]; Mifepristone inhibits the reaction [Corticosterone promotes the reaction [NR3C1 protein binds to PTGS2 promoter]]
Corticosterone results in increased expression of PTGS2 mRNA; Corticosterone results in increased expression of PTGS2 protein		 CTD PMID:15755911 PMID:18650268 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pth parathyroid hormone multiple interactions EXP [Corticosterone co-treated with PTH protein] results in decreased expression of TNFRSF11B mRNA; [Corticosterone co-treated with PTH protein] results in decreased expression of TNFSF11 mRNA CTD PMID:17476578 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 decreases expression EXP Corticosterone results in decreased expression of PTPN3 mRNA CTD PMID:15755911 NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression EXP Corticosterone results in decreased expression of PTTG1 mRNA CTD PMID:15755911 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G Qsox1 quiescin sulfhydryl oxidase 1 increases expression EXP Corticosterone results in increased expression of QSOX1 mRNA CTD PMID:15755911 NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 increases expression EXP Corticosterone results in increased expression of RAPGEF4 mRNA CTD PMID:15755911 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316 		JBrowse link
G Rbp1 retinol binding protein 1 decreases expression EXP Corticosterone results in decreased expression of RBP1 mRNA CTD PMID:15755911 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
G Reg3b regenerating family member 3 beta decreases expression EXP Corticosterone results in decreased expression of REG3B mRNA CTD PMID:15755911 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015 		JBrowse link
G Retn resistin increases expression ISO Corticosterone results in increased expression of RETN mRNA CTD PMID:15809511 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Rfc3 replication factor C subunit 3 decreases expression EXP Corticosterone results in decreased expression of RFC3 mRNA CTD PMID:15755911 NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778 		JBrowse link
G Rfc4 replication factor C subunit 4 decreases expression EXP Corticosterone results in decreased expression of RFC4 mRNA CTD PMID:15755911 NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122 		JBrowse link
G Rgcc regulator of cell cycle increases expression EXP Corticosterone results in increased expression of RGCC mRNA CTD PMID:15755911 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
G RGD1562067 similar to cell division cycle associated 3 decreases expression EXP Corticosterone results in decreased expression of RGD1562067 mRNA CTD PMID:15755911 NCBI chr 9:46,506,533...46,507,525
Ensembl chr 9:46,506,547...46,507,056 		JBrowse link
G Rhoj ras homolog family member J increases expression EXP Corticosterone results in increased expression of RHOJ mRNA CTD PMID:15755911 NCBI chr 6:94,035,307...94,117,642
Ensembl chr 6:94,035,483...94,118,275 		JBrowse link
G Rpa2 replication protein A2 decreases expression EXP Corticosterone results in decreased expression of RPA2 mRNA CTD PMID:15755911 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 decreases expression EXP Corticosterone results in decreased expression of RRM1 mRNA CTD PMID:15755911 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions
decreases expression		 EXP Enalapril inhibits the reaction [Corticosterone results in decreased expression of RUNX2 mRNA] CTD PMID:30423288 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP Corticosterone results in decreased expression of SCD1 mRNA CTD PMID:15755911 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sdc1 syndecan 1 decreases expression EXP Corticosterone results in decreased expression of SDC1 mRNA CTD PMID:15755911 NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264 		JBrowse link
G Sdc2 syndecan 2 decreases expression EXP Corticosterone results in decreased expression of SDC2 mRNA CTD PMID:15755911 NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081 		JBrowse link
G Sdc4 syndecan 4 increases expression EXP Corticosterone results in increased expression of SDC4 mRNA CTD PMID:15755911 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
G Selenop selenoprotein P increases expression EXP Corticosterone results in increased expression of SELENOP mRNA CTD PMID:15755911 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N increases expression EXP Corticosterone results in increased expression of SERPINA3N mRNA CTD PMID:15755911 NCBI chr 6:123,323,632...123,331,166
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression
increases phosphorylation
multiple interactions		 EXP
ISO		 Corticosterone results in increased expression of SGK1 mRNA
[Corticosterone results in increased phosphorylation of SGK1 protein] which results in increased phosphorylation of NDRG1 protein
[Corticosterone results in increased phosphorylation of and results in increased activity of PDK1 protein] which results in increased phosphorylation of and results in increased activity of SGK1 protein
Corticosterone results in increased expression of SGK1 mRNA; Corticosterone results in increased expression of SGK1 protein		 CTD PMID:15755911 PMID:21655274 PMID:31520820 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Shbg sex hormone binding globulin affects binding ISO Corticosterone binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 increases expression
multiple interactions		 EXP Corticosterone results in increased expression of SLC18A3 protein
O-1602 compound inhibits the reaction [Corticosterone results in increased expression of SLC18A3 protein]		 CTD PMID:32733244 NCBI chr16:7,713,630...7,716,491 JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions
increases expression		 ISO Corticosterone inhibits the reaction [Hydrogen Peroxide results in decreased expression of SLC1A2 protein]; Vitamin A promotes the reaction [Corticosterone results in increased expression of SLC1A2 protein] CTD PMID:17138558 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions EXP Corticosterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:9830022 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 decreases activity
multiple interactions		 EXP
ISO		 Corticosterone results in decreased activity of SLC22A3 protein
[Corticosterone results in decreased activity of SLC22A3 protein] inhibits the reaction [Epinephrine results in increased abundance of Epinephrine metabolite]; [Corticosterone results in decreased activity of SLC22A3 protein] which results in decreased abundance of Epinephrine; [Corticosterone results in decreased activity of SLC22A3 protein] which results in decreased import of Phenylephrine; [Corticosterone results in decreased activity of SLC22A3 protein] which results in decreased import of Synephrine; Corticosterone inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Corticosterone inhibits the reaction [SLC22A3 protein results in increased transport of Histamine]; Corticosterone inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium]
Corticosterone inhibits the reaction [SLC22A3 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide]; Corticosterone inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Corticosterone inhibits the reaction [SLC22A3 protein results in increased uptake of Formoterol Fumarate]		 CTD PMID:9830022 PMID:12110607 PMID:12181285 PMID:12411423 PMID:16928864 More... NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases expression
multiple interactions		 EXP Corticosterone results in increased expression of SLC22A8 protein
O-1602 compound inhibits the reaction [Corticosterone results in increased expression of SLC22A8 protein]		 CTD PMID:32733244 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression
multiple interactions		 EXP
ISO		 Corticosterone results in increased expression of SLC2A1 mRNA
[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA]		 CTD PMID:15755911 PMID:29751049 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression
multiple interactions		 EXP
ISO		 Corticosterone results in increased expression of SLC2A4 mRNA
[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA]		 CTD PMID:15755911 PMID:29751049 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc6a15 solute carrier family 6 member 15 multiple interactions
decreases expression		 ISO Edaravone inhibits the reaction [Corticosterone results in decreased expression of SLC6A15 mRNA]; Paroxetine inhibits the reaction [Corticosterone results in decreased expression of SLC6A15 mRNA] CTD PMID:31344373 NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239 		JBrowse link
G Smad2 SMAD family member 2 decreases expression EXP Corticosterone results in decreased expression of SMAD2 mRNA; Corticosterone results in decreased expression of SMAD2 protein CTD PMID:29660438 PMID:32663519 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 decreases expression EXP Corticosterone results in decreased expression of SMAD3 mRNA CTD PMID:29660438 PMID:32663519 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smarcd2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 increases expression EXP Corticosterone results in increased expression of SMARCD2 mRNA CTD PMID:15755911 NCBI chr10:91,193,752...91,202,817
Ensembl chr10:91,193,752...91,204,341 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression EXP Corticosterone results in decreased expression of SOD1 mRNA CTD PMID:22244747 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases activity
decreases expression		 EXP [IGF2R protein co-treated with IGF1R protein] affects the reaction [IGF2 protein inhibits the reaction [Corticosterone results in decreased expression of SOD2 protein]]; IGF2 protein inhibits the reaction [Corticosterone results in decreased expression of SOD2 protein]
Corticosterone results in decreased activity of SOD2 protein
Corticosterone results in decreased expression of SOD2 mRNA; Corticosterone results in decreased expression of SOD2 protein		 CTD PMID:22244747 PMID:24667322 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 increases expression EXP Corticosterone results in increased expression of SORBS2 mRNA CTD PMID:15755911 NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514 		JBrowse link
G Sox4 SRY-box transcription factor 4 decreases expression EXP Corticosterone results in decreased expression of SOX4 mRNA CTD PMID:15755911 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Sox9 SRY-box transcription factor 9 decreases expression EXP Corticosterone results in decreased expression of SOX9 mRNA; Corticosterone results in decreased expression of SOX9 protein CTD PMID:29660438 PMID:32663519 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
decreases expression		 EXP Enalapril inhibits the reaction [Corticosterone results in decreased expression of SPP1 mRNA] CTD PMID:30423288 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP
ISO		 [Corticosterone co-treated with oleoyl-estrone] affects the expression of SREBF1 mRNA
[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA]		 CTD PMID:19545626 PMID:29751049 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Corticosterone co-treated with Isoflurophate] results in increased phosphorylation of STAT3 protein; [Corticosterone co-treated with O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate] results in increased phosphorylation of STAT3 protein CTD PMID:28500787 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stmn1 stathmin 1 decreases expression EXP Corticosterone results in decreased expression of STMN1 mRNA CTD PMID:15755911 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases expression EXP Corticosterone results in increased expression of SULT1A1 mRNA CTD PMID:15755911 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Syn1 synapsin I multiple interactions
decreases expression		 ISO Ascorbic Acid inhibits the reaction [Corticosterone results in decreased expression of SYN1 protein]; Ketamine inhibits the reaction [Corticosterone results in decreased expression of SYN1 protein] CTD PMID:33872575 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396 		JBrowse link
G Synm synemin increases expression EXP Corticosterone results in increased expression of SYNM mRNA CTD PMID:15755911 NCBI chr 1:121,333,712...121,363,652
Ensembl chr 1:121,333,720...121,363,652 		JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP [Mirex co-treated with Corticosterone] results in increased activity of TAT protein; Corticosterone promotes the reaction [[NR3C1 protein binds to TAT promoter] which results in increased expression of TAT mRNA] CTD PMID:2893471 PMID:22465009 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tcf21 transcription factor 21 increases expression EXP Corticosterone results in increased expression of TCF21 mRNA CTD PMID:15755911 NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202 		JBrowse link
G Tcp1 t-complex 1 decreases expression EXP Corticosterone results in decreased expression of TCP1 mRNA CTD PMID:15755911 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase increases activity EXP Corticosterone results in increased activity of TDO2 protein CTD PMID:7306070 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
G Tf transferrin increases expression EXP Corticosterone results in increased expression of TF mRNA CTD PMID:15755911 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression		 EXP Corticosterone inhibits the reaction [TGFB1 protein results in increased secretion of VEGFA protein]
Corticosterone results in decreased expression of TGFB1 mRNA		 CTD PMID:16598785 PMID:29660438 PMID:32663519 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 decreases expression
multiple interactions		 EXP Corticosterone results in decreased expression of TGFBR1 mRNA; Corticosterone results in decreased expression of TGFBR1 protein
Mifepristone inhibits the reaction [Corticosterone results in decreased expression of TGFBR1 mRNA]		 CTD PMID:29660438 PMID:32663519 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgm2 transglutaminase 2 increases expression EXP Corticosterone results in increased expression of TGM2 mRNA CTD PMID:15755911 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Th tyrosine hydroxylase increases expression ISO Corticosterone results in increased expression of TH protein CTD PMID:28186389 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tinagl1 tubulointerstitial nephritis antigen-like 1 increases expression EXP Corticosterone results in increased expression of TINAGL1 mRNA CTD PMID:15755911 NCBI chr 5:142,513,710...142,523,730
Ensembl chr 5:142,513,714...142,523,720 		JBrowse link
G Tk1 thymidine kinase 1 decreases expression EXP Corticosterone results in decreased expression of TK1 mRNA CTD PMID:15755911 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR4 protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR4 protein]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein] CTD PMID:29751049 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr5 toll-like receptor 5 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein] CTD PMID:29751049 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tnc tenascin C decreases expression EXP Corticosterone results in decreased expression of TNC mRNA CTD PMID:15755911 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO
EXP		 [Corticosterone co-treated with Isoflurophate] results in increased expression of TNF mRNA; [Corticosterone co-treated with O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate] results in increased expression of TNF mRNA; [Corticosterone co-treated with Physostigmine] results in increased expression of TNF mRNA; [Corticosterone co-treated with Pyridostigmine Bromide] results in increased expression of TNF mRNA; [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TNF mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TNF mRNA]; Corticosterone promotes the reaction [Isoflurophate results in increased expression of TNF mRNA]; Corticosterone promotes the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in increased expression of TNF mRNA]
Corticosterone results in increased expression of TNF protein
Corticosterone results in increased expression of TNF mRNA
[Corticosterone co-treated with Isoflurophate] results in increased expression of TNF mRNA; O-1602 compound inhibits the reaction [Corticosterone results in increased expression of TNF protein]		 CTD PMID:28500787 PMID:28782715 PMID:29751049 PMID:29846716 PMID:32733244 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression
increases expression
multiple interactions		 EXP Corticosterone results in decreased expression of TNFRSF11B mRNA
Corticosterone results in increased expression of TNFRSF11B mRNA
[Corticosterone co-treated with PTH protein] results in decreased expression of TNFRSF11B mRNA; Mifepristone inhibits the reaction [Corticosterone results in increased expression of TNFRSF11B mRNA]		 CTD PMID:17476578 PMID:29981921 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions
decreases expression
increases expression		 EXP [Corticosterone co-treated with PTH protein] results in decreased expression of TNFSF11 mRNA; Mifepristone inhibits the reaction [Corticosterone results in decreased expression of TNFSF11 mRNA]
Corticosterone results in increased expression of TNFSF11 mRNA		 CTD PMID:17476578 PMID:29981921 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression EXP Corticosterone results in decreased expression of TOP2A mRNA CTD PMID:15755911 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tpbg trophoblast glycoprotein decreases expression EXP Corticosterone results in decreased expression of TPBG mRNA CTD PMID:15755911 NCBI chr 8:86,793,953...86,797,324
Ensembl chr 8:86,793,749...86,797,741 		JBrowse link
G Tpd52l1 TPD52 like 1 increases expression EXP Corticosterone results in increased expression of TPD52L1 mRNA CTD PMID:15755911 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109 		JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO
EXP		 [Testosterone co-treated with Estradiol co-treated with Corticosterone] promotes the reaction [AR protein binds to TRAF6 protein]; [Testosterone co-treated with Estradiol co-treated with Corticosterone] promotes the reaction [ESR1 protein binds to TRAF6 protein]
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [Estradiol inhibits the reaction [Corticosterone results in increased expression of TRAF6 protein]]; Corticosterone results in increased expression of and results in increased ubiquitination of TRAF6 protein; Estradiol inhibits the reaction [Corticosterone results in increased expression of and results in increased ubiquitination of TRAF6 protein]; Estradiol promotes the reaction [Testosterone inhibits the reaction [Corticosterone results in increased ubiquitination of TRAF6 protein]]; Flutamide inhibits the reaction [Estradiol inhibits the reaction [Corticosterone results in increased expression of TRAF6 protein]]; Testosterone inhibits the reaction [Corticosterone results in increased ubiquitination of TRAF6 protein]; Testosterone promotes the reaction [Estradiol inhibits the reaction [Corticosterone results in increased expression of and results in increased ubiquitination of TRAF6 protein]]		 CTD PMID:29625166 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trhr thyrotropin releasing hormone receptor increases expression EXP Corticosterone results in increased expression of TRHR mRNA CTD PMID:15755911 NCBI chr 7:75,348,672...75,393,310
Ensembl chr 7:75,348,672...75,393,309 		JBrowse link
G Trim54 tripartite motif-containing 54 increases expression EXP Corticosterone results in increased expression of TRIM54 mRNA CTD PMID:15755911 NCBI chr 6:25,239,340...25,258,511
Ensembl chr 6:25,239,340...25,258,511 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression
multiple interactions		 EXP Corticosterone results in increased expression of TSC22D3 mRNA; Corticosterone results in increased expression of TSC22D3 protein
TSC22D3 protein affects the reaction [Corticosterone results in decreased susceptibility to Doxorubicin]		 CTD PMID:24480152 PMID:31520820 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
G Tspo translocator protein increases expression EXP Corticosterone results in increased expression of TSPO mRNA CTD PMID:15755911 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression EXP Corticosterone results in decreased expression of TUBB5 mRNA CTD PMID:15755911 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression EXP Corticosterone results in decreased expression of UBE2C mRNA CTD PMID:15755911 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339 		JBrowse link
G Vcan versican decreases expression EXP Corticosterone results in decreased expression of VCAN mRNA CTD PMID:15755911 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
affects expression		 EXP
ISO		 Corticosterone inhibits the reaction [TGFB1 protein results in increased secretion of VEGFA protein]
Corticosterone results in increased expression of VEGFA protein
Corticosterone affects the expression of VEGFA protein		 CTD PMID:16598785 PMID:21647420 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 decreases expression EXP Corticosterone results in decreased expression of WARS1 mRNA CTD PMID:15755911 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269 		JBrowse link
G Wt1 WT1 transcription factor decreases expression EXP Corticosterone results in decreased expression of WT1 mRNA; Corticosterone results in decreased expression of WT1 protein CTD PMID:31306741 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
G Xpo1 exportin 1 decreases expression EXP Corticosterone results in decreased expression of XPO1 mRNA CTD PMID:15755911 NCBI chr14:97,233,263...97,275,536
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
G Zfp36 zinc finger protein 36 increases expression EXP Corticosterone results in increased expression of ZFP36 mRNA CTD PMID:15755911 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
11-dehydrocorticosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases metabolic processing
affects response to substance
multiple interactions
affects abundance
increases reduction		 ISO
EXP		 HSD11B1 protein results in increased metabolism of 11-dehydrocorticosterone
HSD11B1 gene affects the susceptibility to 11-dehydrocorticosterone
[HSD11B1 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone; [HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] which results in increased chemical synthesis of Corticosterone; Resveratrol inhibits the reaction [HSD11B1 protein results in increased metabolism of 11-dehydrocorticosterone]; Ziram inhibits the reaction [[HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] which results in increased chemical synthesis of Corticosterone]; Ziram inhibits the reaction [HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone]
HSD11B1 gene mutant form affects the abundance of 11-dehydrocorticosterone		 CTD PMID:16751407 PMID:23814014 PMID:25061560 PMID:26859423 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions EXP [HSD11B2 protein results in increased metabolism of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone; [HSD11B2 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone; Ziram inhibits the reaction [[HSD11B2 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone] CTD PMID:26859423 PMID:32243540 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 ISO 11-dehydrocorticosterone results in increased expression of IL6 mRNA
11-dehydrocorticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of IL6 mRNA]		 CTD PMID:30993381 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions
increases expression		 EXP Carbenoxolone inhibits the reaction [11-dehydrocorticosterone results in increased expression of SGK1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [11-dehydrocorticosterone results in increased expression of SGK1 mRNA] CTD PMID:16533503 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19751
    chemical entity 19749
      group 19713
        organic group 18846
          3-oxo-Delta(4)-steroid group 9154
            3-oxo-Delta(4) steroid 9154
              corticosterone 347
                11-dehydrocorticosterone 4
                11-deoxycorticosterone pivalate 0
                18-hydroxycorticosterone 0
                20beta-dihydrocorticosterone 0
                5alpha-dihydrocorticosterone 0
                5beta-dihydrocorticosterone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19751
    subatomic particle 19749
      composite particle 19749
        hadron 19749
          baryon 19749
            nucleon 19749
              atomic nucleus 19749
                atom 19749
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19644
                        carbon atom 19640
                          organic molecular entity 19640
                            organic group 18846
                              organic divalent group 18832
                                organodiyl group 18832
                                  carbonyl group 18799
                                    carbonyl compound 18799
                                      ketone 17108
                                        oxyketone 8796
                                          alpha-oxyketone 8796
                                            alpha-hydroxy ketone 8796
                                              primary alpha-hydroxy ketone 7674
                                                corticosterone 347
                                                  11-dehydrocorticosterone 4
                                                  11-deoxycorticosterone pivalate 0
                                                  18-hydroxycorticosterone 0
                                                  20beta-dihydrocorticosterone 0
                                                  5alpha-dihydrocorticosterone 0
                                                  5beta-dihydrocorticosterone 0
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