Ddx19b (DEAD-box helicase 19B) - Rat Genome Database
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Gene: Ddx19b (DEAD-box helicase 19B) Rattus norvegicus
Analyze
Symbol: Ddx19b
Name: DEAD-box helicase 19B
RGD ID: 1593382
Description: Predicted to have RNA binding activity and RNA helicase activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to localize to cytoplasmic stress granule and nuclear envelope. Orthologous to several human genes including DDX19B (DEAD-box helicase 19B); PARTICIPATES IN NXF1-NXT1 export pathway; INTERACTS WITH acrylamide; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP-dependent RNA helicase DDX19B; DEAD (Asp-Glu-Ala-As) box polypeptide 19B; DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B; LOC690693; similar to DDX19 homolog; Zd10a; zinc responsive protein Zd10A; zinc responsive protein ZD10B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21938,968,215 - 38,998,907 (-)NCBI
Rnor_6.0 Ensembl1943,217,161 - 43,275,287 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01943,217,199 - 43,246,196 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01954,045,135 - 54,061,405 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01954,067,897 - 54,072,633 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,924,875 - 40,947,452 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1938,360,365 - 38,385,589 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:15361827   PMID:19056867   PMID:19946888  


Genomics

Comparative Map Data
Ddx19b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21938,968,215 - 38,998,907 (-)NCBI
Rnor_6.0 Ensembl1943,217,161 - 43,275,287 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01943,217,199 - 43,246,196 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01954,045,135 - 54,061,405 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01954,067,897 - 54,072,633 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,924,875 - 40,947,452 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1938,360,365 - 38,385,589 (-)NCBICelera
Cytogenetic Map19q12NCBI
DDX19B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1670,289,663 - 70,335,305 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1670,289,663 - 70,335,283 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1670,299,194 - 70,372,582 (+)EnsemblGRCh38hg38GRCh38
GRCh381670,289,767 - 70,335,305 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371670,323,670 - 70,367,735 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh371670,323,670 - 70,369,208 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361668,890,573 - 68,925,232 (+)NCBINCBI36hg18NCBI36
Build 341668,890,598 - 68,925,230NCBI
Celera1655,160,454 - 55,195,108 (-)NCBI
Cytogenetic Map16q22.1NCBI
HuRef1656,156,341 - 56,200,270 (+)NCBIHuRef
CHM1_11671,731,134 - 71,775,217 (+)NCBICHM1_1
Ddx19b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398111,729,818 - 111,758,383 (-)NCBIGRCm39mm39
GRCm388111,003,186 - 111,031,751 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8111,003,188 - 111,031,751 (-)EnsemblGRCm38mm10GRCm38
MGSCv378113,527,088 - 113,551,664 (-)NCBIGRCm37mm9NCBIm37
MGSCv368113,889,863 - 113,914,439 (-)NCBImm8
Celera8115,227,150 - 115,251,693 (-)NCBICelera
Cytogenetic Map8E1NCBI
Ddx19b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554843,120,480 - 3,137,917 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554843,120,480 - 3,137,917 (+)NCBIChiLan1.0ChiLan1.0
LOC100984626
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11670,131,115 - 70,167,548 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1670,126,833 - 70,167,548 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01654,683,291 - 54,718,133 (-)NCBIMhudiblu_PPA_v0panPan3
DDX19B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl613,325,540 - 13,392,110 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1613,328,241 - 13,358,139 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2613,239,713 - 13,271,120 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103233156
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1553,438,552 - 53,480,623 (+)NCBI
ChlSab1.1 Ensembl553,443,037 - 53,481,987 (+)Ensembl
Ddx19b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474612,569,308 - 12,592,168 (+)NCBI

Position Markers
RH131624  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01943,242,586 - 43,242,805NCBIRnor6.0
Rnor_5.01954,069,023 - 54,069,242UniSTSRnor5.0
RGSC_v3.41940,924,196 - 40,924,415UniSTSRGSC3.4
Celera1938,363,756 - 38,363,975UniSTS
RH 3.4 Map31367.1UniSTS
Cytogenetic Map19q12UniSTS
RH142652  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01943,241,565 - 43,241,864NCBIRnor6.0
Rnor_5.01954,068,002 - 54,068,301UniSTSRnor5.0
RGSC_v3.41940,925,137 - 40,925,436UniSTSRGSC3.4
Celera1938,364,697 - 38,364,996UniSTS
RH 3.4 Map19476.6UniSTS
Cytogenetic Map19q12UniSTS
AI144819  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01943,241,255 - 43,241,473NCBIRnor6.0
RGSC_v3.41940,925,528 - 40,925,746UniSTSRGSC3.4
Celera1938,365,088 - 38,365,306UniSTS
RH 3.4 Map19475.6UniSTS
Cytogenetic Map19q12UniSTS
RH139434  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01943,245,841 - 43,246,048NCBIRnor6.0
Rnor_6.01943,245,886 - 43,246,048NCBIRnor6.0
Rnor_5.01954,072,278 - 54,072,485UniSTSRnor5.0
Rnor_5.01954,072,323 - 54,072,485UniSTSRnor5.0
RGSC_v3.41940,920,953 - 40,921,160UniSTSRGSC3.4
RGSC_v3.41940,920,953 - 40,921,115UniSTSRGSC3.4
Celera1938,360,513 - 38,360,720UniSTS
Celera1938,360,513 - 38,360,675UniSTS
RH 3.4 Map19482.1UniSTS
Cytogenetic Map19q12UniSTS
SHGC-60774  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01943,240,181 - 43,240,306NCBIRnor6.0
Rnor_6.01943,269,728 - 43,269,853NCBIRnor6.0
Rnor_5.01954,097,981 - 54,098,106UniSTSRnor5.0
Cytogenetic Map19q12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19104464846044648Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19195770746957707Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19243296347217667Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19243296362275575Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)19370183548701835Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)19370183548701835Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19500757143907843Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19650676160220581Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19807254547318201Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191130392747879277Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191702800352538299Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191899398262275575Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191917749562275575Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)192140778762275575Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)192445572643907843Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192481825762275575Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)193299439262275575Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)193791679960220451Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193791679960220451Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000024793   ⟹   ENSRNOP00000024793
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1943,251,539 - 43,271,865 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082566   ⟹   ENSRNOP00000071135
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1943,217,161 - 43,275,287 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000084462   ⟹   ENSRNOP00000069097
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1943,220,576 - 43,241,297 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087474   ⟹   ENSRNOP00000074386
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1943,220,576 - 43,270,841 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091788   ⟹   ENSRNOP00000070488
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1943,220,508 - 43,241,536 (+)Ensembl
RefSeq Acc Id: NM_001005895   ⟹   NP_001005895
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21938,968,215 - 38,993,966 (-)NCBI
Rnor_6.01943,220,445 - 43,246,196 (+)NCBI
Rnor_5.01954,045,135 - 54,061,405 (+)NCBI
Rnor_5.01954,067,897 - 54,072,633 (+)NCBI
Celera1938,360,365 - 38,385,589 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008772534   ⟹   XP_008770756
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21938,968,217 - 38,997,234 (-)NCBI
Rnor_6.01943,217,199 - 43,246,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601362   ⟹   XP_017456851
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01943,222,668 - 43,246,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098000   ⟹   XP_038953928
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21938,968,217 - 38,998,907 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001005895 (Get FASTA)   NCBI Sequence Viewer  
  XP_008770756 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953928 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAQ73499 (Get FASTA)   NCBI Sequence Viewer  
  AAU84666 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001005895   ⟸   NM_001005895
- Sequence:
RefSeq Acc Id: XP_008770756   ⟸   XM_008772534
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JZQ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456851   ⟸   XM_017601362
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000069097   ⟸   ENSRNOT00000084462
RefSeq Acc Id: ENSRNOP00000071135   ⟸   ENSRNOT00000082566
RefSeq Acc Id: ENSRNOP00000074386   ⟸   ENSRNOT00000087474
RefSeq Acc Id: ENSRNOP00000024793   ⟸   ENSRNOT00000024793
RefSeq Acc Id: ENSRNOP00000070488   ⟸   ENSRNOT00000091788
RefSeq Acc Id: XP_038953928   ⟸   XM_039098000
- Peptide Label: isoform X2
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701149
Promoter ID:EPDNEW_R11665
Type:multiple initiation site
Name:Ddx19b_3
Description:DEAD-box helicase 19B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11666  EPDNEW_R11667  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01943,217,214 - 43,217,274EPDNEW
RGD ID:13701142
Promoter ID:EPDNEW_R11666
Type:initiation region
Name:Ddx19b_1
Description:DEAD-box helicase 19B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11667  EPDNEW_R11665  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01943,220,453 - 43,220,513EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593382 AgrOrtholog
Ensembl Genes ENSRNOG00000018033 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000069097 UniProtKB/TrEMBL
  ENSRNOP00000070488 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000071135 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000074386 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082566 UniProtKB/TrEMBL
  ENSRNOT00000084462 UniProtKB/TrEMBL
  ENSRNOT00000087474 UniProtKB/TrEMBL
  ENSRNOT00000091788 ENTREZGENE, UniProtKB/TrEMBL
InterPro DEAD-like_N UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAD/DEAH_N UniProtKB/TrEMBL
  helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNA_helicase_DEAD_Q_motif UniProtKB/TrEMBL
KEGG Report rno:690693 UniProtKB/TrEMBL
NCBI Gene 690693 ENTREZGENE
Pfam DEAD UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PhenoGen Ddx19b PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  Q_MOTIF UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2JUH2_RAT UniProtKB/TrEMBL
  A0A0G2JY21_RAT UniProtKB/TrEMBL
  A0A0G2JZQ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K7X6_RAT UniProtKB/TrEMBL
  Q5XLP8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Ddx19b  DEAD-box helicase 19B  Ddx19b  DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-01 Ddx19b  DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B  Ddx19b  DEAD (Asp-Glu-Ala-As) box polypeptide 19B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Ddx19b  DEAD (Asp-Glu-Ala-As) box polypeptide 19B  LOC690693  similar to DDX19 homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC690693  similar to DDX19 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL