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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-(trimethylammonio)butanoate
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Accession:CHEBI:16244 term browser browse the term
Definition:An amino-acid betaine gamma-aminobutyric acid zwitterion in which all of the hydrogens attached to the nitrogen are replaced by methyl groups.
Synonyms:related_synonym: 3-Dehydroxycarnitine;   4-(N-trimethylamino)butyrate;   4-(trimethylamino)butanoate;   4-butyrobetaine;   Actinine;   Formula=C7H15NO2;   InChI=1S/C7H15NO2/c1-8(2,3)6-4-5-7(9)10/h4-6H2,1-3H3;   InChIKey=JHPNVNIEXXLNTR-UHFFFAOYSA-N;   SMILES=C[N+](C)(C)CCCC([O-])=O;   butyrobetaine;   deoxycarnitine;   gamma-Butyrobetain;   gamma-butyrobetaine
 alt_id: CHEBI:12047;   CHEBI:20484
 xref: Beilstein:3538300;   CAS:407-64-7;   ECMDB:ECMDB21336;   HMDB:HMDB0006831
 xref_mesh: MESH:C002889
 xref: MetaCyc:GAMMA-BUTYROBETAINE;   PMID:3148329;   PMID:398096;   Reaxys:3538300
 cyclic_relationship: is_conjugate_base_of CHEBI:1941


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4-(trimethylammonio)butanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbox1 gamma-butyrobetaine hydroxylase 1 multiple interactions ISO [BBOX1 protein co-treated with Ketoglutaric Acids] results in increased metabolism of gamma-butyrobetaine CTD PMID:21439360 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
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G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of gamma-butyrobetaine] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        biochemical role 19389
          metabolite 19364
            butyrate 84
              gamma-aminobutyrate 2
                4-(trimethylammonio)butanoate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    main group molecular entity 19716
                      s-block molecular entity 19502
                        hydrogen molecular entity 19498
                          hydrides 18852
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  ammonium 8228
                                    ammonium ion derivative 8224
                                      quaternary ammonium ion 5108
                                        quaternary nitrogen compound 619
                                          ammonium betaine 337
                                            amino-acid betaine 242
                                              4-(trimethylammonio)butanoate 2
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