RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Poisoning
Accession: DOID:9000046
browse the term
Definition: A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent.
Synonyms: exact_synonym: Poisonings
related_synonym: Benzene toxicity, susceptibility to
primary_id: MESH:D011041
xref: EFO:0008546
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Abcb1a
ATP binding cassette subfamily B member 1A
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:23562926
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Ache
acetylcholinesterase
IDA ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:17098105 PMID:19453088
RGD:5688054
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Alb
albumin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:10511253
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Bche
butyrylcholinesterase
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:20176007 PMID:20513442 PMID:21620937 PMID:21683774 PMID:29183815
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20044985
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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Cdkn2b
cyclin-dependent kinase inhibitor 2B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20044985
NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
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Csf3
colony stimulating factor 3
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15727166
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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Cst3
cystatin C
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22525860
NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
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Cyp4f18
cytochrome P450, family 4, subfamily f, polypeptide 18
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20036648
NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
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Epo
erythropoietin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15727166
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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Gcg
glucagon
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:7629900
NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
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Gsk3b
glycogen synthase kinase 3 beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22975441
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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Hand1
heart and neural crest derivatives expressed 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21964422
NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213
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Il1a
interleukin 1 alpha
treatment
ISO
RGD
PMID:1868253 PMID:2258610
RGD:11051971 , RGD:11059514
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Nqo1
NAD(P)H quinone dehydrogenase 1
ISO
ClinVar Annotator: match by term: Benzene toxicity, susceptibility to
ClinVar
PMID:1737339 PMID:6933553 PMID:9000600 PMID:9230185 PMID:9328142 PMID:9593466 PMID:9855009 PMID:10393869 PMID:10393963 PMID:18511948 PMID:21964527 PMID:25741868 More...
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Prkdc
protein kinase, DNA-activated, catalytic subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20036648
NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
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Slc22a2
solute carrier family 22 member 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:22525860
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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Xirp1
xin actin-binding repeat containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21964422
NCBI chr 8:119,744,778...119,757,547
Ensembl chr 8:119,747,419...119,757,349
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Cck
cholecystokinin
susceptibility
ISO
DNA:SNP:promoter: -45C>T (human)
RGD
PMID:10235270
RGD:406351024
NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
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Cnr1
cannabinoid receptor 1
ISO
RGD
PMID:11841893
RGD:1626329
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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Ngf
nerve growth factor
ISO
protein:increased expression:serum
RGD
PMID:17434673
RGD:401965399
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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Ptgs2
prostaglandin-endoperoxide synthase 2
ISO
RGD
PMID:16318954
RGD:5688289
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Slc6a3
solute carrier family 6 member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27219321
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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Cacna1d
calcium voltage-gated channel subunit alpha1 D
susceptibility
IEP
mRNA, protein:increased expression:inferior colliculus (rat)
RGD
PMID:25556199
RGD:152985539
NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
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Drd2
dopamine receptor D2
susceptibility
ISO
DNA:SNP:exon:A>G(human)
RGD
PMID:23238469
RGD:401959213
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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Pdyn
prodynorphin
ISO
mRNA:increased expression:brain
RGD
PMID:15869750
RGD:401850576
NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
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Slc29a1
solute carrier family 29 member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21283641
NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
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Slc6a3
solute carrier family 6 member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27219321
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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Aif1
allograft inflammatory factor 1
IEP
protein:increased expression:cortex, hippocampus (rat)
RGD
PMID:18585922
RGD:2313030
NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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Cirbp
cold inducible RNA binding protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24223948
NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
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Aldh2
aldehyde dehydrogenase 2 family member
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26711020
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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Ankk1
ankyrin repeat and kinase domain containing 1
ISO
DNA:SNP:exon:rs1800497(human)
RGD
PMID:18669994
RGD:401959336
NCBI chr 8:49,779,862...49,788,024
Ensembl chr 8:49,779,862...49,788,024
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Drd2
dopamine receptor D2
ISO
DNA:SNP:cds:957C>T(human)
RGD
PMID:18669994
RGD:401959336
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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Foxo4
forkhead box O4
IEP
protein:increased phosphorylation:small intestine:
RGD
PMID:23292333
RGD:10402360
NCBI chr X:66,385,241...66,392,115
Ensembl chr X:66,385,558...66,392,115
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Gsr
glutathione-disulfide reductase
treatment
IEP
RGD
PMID:24972622
RGD:10401897
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Hectd4
HECT domain E3 ubiquitin protein ligase 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:35713687
NCBI chr12:35,182,165...35,330,935
Ensembl chr12:35,182,154...35,330,987
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Igf1
insulin-like growth factor 1
IEP
RGD
PMID:23016131
RGD:10402569
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igf1r
insulin-like growth factor 1 receptor
IEP
RGD
PMID:23016131
RGD:10402569
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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Igf2
insulin-like growth factor 2
IEP
RGD
PMID:23016131
RGD:10402569
NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
treatment
IMP
RGD
PMID:18093169
RGD:408345248
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Htr2a
5-hydroxytryptamine receptor 2A
ISO
DNA:SNP:promoter:-1438G>A
RGD
PMID:11842624
RGD:401900738
NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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Akap9
A-kinase anchoring protein 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
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Alad
aminolevulinate dehydratase
IEP
protein:decreased activity:blood (rat)
RGD
PMID:19022878
RGD:4144202
NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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Aqp9
aquaporin 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19805235
NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
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As3mt
arsenite methyltransferase
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:21447609 PMID:26366667 PMID:35226250
NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872
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Atxn7
ataxin 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr15:11,117,360...11,262,818
Ensembl chr15:11,118,886...11,263,106
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Ccl20
C-C motif chemokine ligand 20
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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Ccl4
C-C motif chemokine ligand 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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Ccrl2
C-C motif chemokine receptor like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 8:111,034,279...111,036,914
Ensembl chr 8:111,034,279...111,036,664
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Cd44
CD44 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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Cd83
CD83 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
ISO
protein:increased expression:skin:
RGD
PMID:11860939
RGD:8662429
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Crp
C-reactive protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22521605
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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Cxcl2
C-X-C motif chemokine ligand 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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Ercc1
ERCC excision repair 1, endonuclease non-catalytic subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12569548
NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
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Ercc3
ERCC excision repair 3, TFIIH core complex helicase subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12569548
NCBI chr18:23,883,613...23,914,326
Ensembl chr18:23,883,580...23,914,329
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Ercc4
ERCC excision repair 4, endonuclease catalytic subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12569548
NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
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Gadd45b
growth arrest and DNA-damage-inducible, beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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Golga4
golgin A4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 8:118,208,200...118,285,003
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Gsr
glutathione-disulfide reductase
IEP
RGD
PMID:25209654
RGD:10401880
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Hspa1b
heat shock protein family A (Hsp70) member 1B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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Id2
inhibitor of DNA binding 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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Ier3
immediate early response 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:35226250
NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
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Il1a
interleukin 1 alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il1rn
interleukin 1 receptor antagonist
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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Inpp5a
inositol polyphosphate-5-phosphatase A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25759212
NCBI chr 1:194,190,086...194,380,429
Ensembl chr 1:194,190,393...194,380,428
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Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
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Krt10
keratin 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19953893
NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
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Mettl14
methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:35226250
NCBI chr 2:211,530,598...211,546,845
Ensembl chr 2:211,530,602...211,546,821
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Minpp1
multiple inositol-polyphosphate phosphatase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 1:230,354,483...230,379,730
Ensembl chr 1:230,354,438...230,379,730
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Mir145
microRNA 145
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29705342
NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
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Mir155
microRNA 155
ISO
miRNA:increased expression:serum
RGD
PMID:27913196
RGD:25314296
NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
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Mt1
metallothionein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19953893
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Mthfr
methylenetetrahydrofolate reductase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24384392
NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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N4bp2l2
NEDD4 binding protein 2-like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr12:137,342...200,292
Ensembl chr12:103,590...197,784
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Ndufb8
NADH:ubiquinone oxidoreductase subunit B8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 1:243,408,656...243,413,715
Ensembl chr 1:243,408,619...243,413,817
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Nlrp3
NLR family, pyrin domain containing 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:35226250
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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Nr4a2
nuclear receptor subfamily 4, group A, member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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Pde4b
phosphodiesterase 4B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
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Peli1
pellino E3 ubiquitin protein ligase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285
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Pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
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Pias1
protein inhibitor of activated STAT, 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905
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Pnp
purine nucleoside phosphorylase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18414634
NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986
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Ptx3
pentraxin 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
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Rfx3
regulatory factor X3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 1:225,449,872...225,709,622
Ensembl chr 1:225,456,187...225,709,402
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Rgs1
regulator of G-protein signaling 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984
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Rnf20
ring finger protein 20
ISO
protein:increased expression:urine (human)
RGD
PMID:21136906
RGD:9831407
NCBI chr 5:63,976,063...64,001,754
Ensembl chr 5:63,976,045...64,001,754
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Rufy3
RUN and FYVE domain containing 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr14:19,431,530...19,506,476
Ensembl chr14:19,432,524...19,507,004
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Sfpq
splicing factor proline and glutamine rich
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
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Skil
SKI-like proto-oncogene
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
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Sod2
superoxide dismutase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sox18
SRY-box transcription factor 18
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290
G
Srp68
signal recognition particle 68
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr10:101,481,213...101,508,035
Ensembl chr10:101,481,212...101,508,035
G
Ssbp1
single stranded DNA binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135
G
Taf1d
TATA-box binding protein associated factor, RNA polymerase I subunit D
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 8:12,146,511...12,156,647
Ensembl chr 8:12,146,605...12,156,618
G
Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tnfaip6
TNF alpha induced protein 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
G
Tnik
TRAF2 and NCK interacting kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 2:111,184,352...111,587,993
Ensembl chr 2:111,184,387...111,580,750
G
Tp53
tumor protein p53
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18621066 PMID:19203779
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
G
Tra2a
transformer 2 alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 4:78,220,838...78,239,737
Ensembl chr 4:78,220,883...78,239,712
G
Trappc10
trafficking protein particle complex subunit 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr20:10,438,737...10,499,074
Ensembl chr20:10,438,737...10,499,074
G
Ube2e1
ubiquitin-conjugating enzyme E2E 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr15:7,439,751...7,493,410
Ensembl chr15:7,439,759...7,493,400
G
Uso1
USO1 vesicle transport factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr14:15,866,638...15,932,185
Ensembl chr14:15,866,638...15,932,171
G
Usp13
ubiquitin specific peptidase 13
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 2:115,576,912...115,689,153
Ensembl chr 2:115,577,091...115,686,222
G
Zfand6
zinc finger AN1-type containing 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 1:138,581,002...138,652,052
Ensembl chr 1:138,581,002...138,651,939
G
Zfp267
zinc finger protein 267
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16835338
NCBI chr 2:119,017,280...119,035,885
Ensembl chr 2:119,017,285...119,031,900
G
Ache
acetylcholinesterase
treatment
IEP
RGD
PMID:27491636
RGD:152995409
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
G
Ada
adenosine deaminase
treatment
IEP
RGD
PMID:27491636
RGD:152995409
NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
G
Cpa1
carboxypeptidase A1
IEP
protein:increased activity:small intestine (rat)
RGD
PMID:15865404
RGD:1578424
NCBI chr 4:59,257,417...59,263,544
Ensembl chr 4:59,257,417...59,263,544
G
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
IEP
protein:increased activity:plasma:
RGD
PMID:24361405
RGD:9685430
NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
G
Gpx1
glutathione peroxidase 1
treatment
IEP
RGD
PMID:24954678
RGD:11352769
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Gpx4
glutathione peroxidase 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20643113
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
G
Gsr
glutathione-disulfide reductase
treatment
IEP
RGD
PMID:24200859
RGD:10401881
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Htt
huntingtin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19845833
NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
G
Il6
interleukin 6
IEP
in males;protein:increased expression, increased activity:plasma (rat)
RGD
PMID:19462680
RGD:11060270
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Mt3
metallothionein 3
ISO
RGD
PMID:20371971
RGD:6480494
NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
G
Nudt1
nudix hydrolase 1
IEP
RGD
PMID:11817101
RGD:633232
NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826
G
Selenop
selenoprotein P
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20643113
NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
G
Chrna3
cholinergic receptor nicotinic alpha 3 subunit
IEP
RGD
PMID:24704181
RGD:151347543
NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165
G
Hmox1
heme oxygenase 1
IEP IDA
RGD
PMID:20422170 PMID:19520142
RGD:4145288 , RGD:4145306
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Mbp
myelin basic protein
IEP
protein:decreased expression:brain:
RGD
PMID:23146304
RGD:7327205
NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
G
Nos1
nitric oxide synthase 1
IMP
RGD
PMID:14761684
RGD:13825130
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
G
Xdh
xanthine dehydrogenase
IMP IEP
RGD
PMID:17433579 PMID:8248931
RGD:13209022 , RGD:13210748
NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
G
Fadd
Fas associated via death domain
treatment
IEP
RGD
PMID:25687490
RGD:11341810
NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
G
Gfer
growth factor, augmenter of liver regeneration
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15968720
NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869
G
Gpx1
glutathione peroxidase 1
IEP
RGD
PMID:18306454
RGD:2312624
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Gpx2
glutathione peroxidase 2
treatment
IEP
RGD
PMID:31018559
RGD:401827907
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
G
Gpx3
glutathione peroxidase 3
treatment
IEP
RGD
PMID:31018559 PMID:18306454
RGD:401827907 , RGD:2312624
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
G
Hmox1
heme oxygenase 1
IEP
RGD
PMID:24748974
RGD:10755718
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Ltf
lactotransferrin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:16141546
NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
G
Nqo1
NAD(P)H quinone dehydrogenase 1
treatment
IEP
RGD
PMID:23684718
RGD:11035220
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Ucp2
uncoupling protein 2
IEP
protein:increased expression:liver
RGD
PMID:19104935
RGD:7204431
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
G
Aass
aminoadipate-semialdehyde synthase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
G
Abcb11
ATP binding cassette subfamily B member 11
severity
ISO
DNA:SNP: :rs2287616(human)
RGD
PMID:27293027
RGD:14402413
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
G
Abcb1a
ATP binding cassette subfamily B member 1A
severity susceptibility
ISO
DNA:SNP::2677G>T/A(rs2032582)(human) CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20623750 PMID:26134275 PMID:26134275 PMID:27296832
RGD:11041130 , RGD:14700895
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
G
Abcb1b
ATP-binding cassette, sub-family B member 1B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27193730
NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
G
Abcc1
ATP binding cassette subfamily C member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18466103
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
G
Abcc2
ATP binding cassette subfamily C member 2
susceptibility
ISO
CTD Direct Evidence: marker/mechanism DNA:polymorphism:promoter:-24C>T(human)
CTD RGD
PMID:18381794 PMID:18466103 PMID:17241877 PMID:25196354
RGD:14700814 , RGD:14700812
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
G
Abi1
abl-interactor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792
G
Ace
angiotensin I converting enzyme
IEP
mRNA:increased expression:liver (rat)
RGD
PMID:25143335
RGD:25671447
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
G
Acox3
acyl-CoA oxidase 3, pristanoyl
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr14:75,133,986...75,176,767
Ensembl chr14:75,094,676...75,176,205
G
Acsl1
acyl-CoA synthetase long-chain family member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
G
Actb
actin, beta
IEP ISO
mRNA:increased expression:liver CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:25231249 PMID:22563491
RGD:9587759
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
G
Actn4
actinin alpha 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
G
Actr3
actin related protein 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124
G
Ada
adenosine deaminase
IEP
protein:increased expression:liver
RGD
PMID:21161045
RGD:5128859
NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
G
Adam8
ADAM metallopeptidase domain 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24646716
NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
G
Adipoq
adiponectin, C1Q and collagen domain containing
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:20709802
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
G
Adipor2
adiponectin receptor 2
severity
IEP
associated with obesity, LPS;mRNA:decreased expression:liver (rat)
RGD
PMID:23838384
RGD:8695926
NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
G
Adora2b
adenosine A2B receptor
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:35292334
NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
G
Agt
angiotensinogen
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29499335
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
G
Ahr
aryl hydrocarbon receptor
ISO IEP
CTD Direct Evidence: marker/mechanism|therapeutic mRNA:decreased expression:liver (rat)
CTD RGD
PMID:21890736 PMID:34848246 PMID:28959666
RGD:401794432
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
G
Aifm1
apoptosis inducing factor, mitochondria associated 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25743375
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
G
Ak4
adenylate kinase 4
IEP
protein:increased expression:liver (rat)
RGD
PMID:16538043
RGD:2301096
NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
G
Akr1a1
aldo-keto reductase family 1 member A1
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:32805337 PMID:29763686
RGD:27226688
NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
G
Alb
albumin
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:18779383 PMID:22310181 PMID:27567545
RGD:14694844
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
G
Aldh1l2
aldehyde dehydrogenase 1 family, member L2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776
G
Aldh2
aldehyde dehydrogenase 2 family member
severity susceptibility
IEP ISO
protein:increased expression:liver DNA:deletion:exon 3 (mouse)
RGD
PMID:21138988 PMID:30121625 PMID:24492981
RGD:7241599 , RGD:15036810 , RGD:14975148
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
G
Aldh9a1
aldehyde dehydrogenase 9 family, member A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568
G
Aldob
aldolase, fructose-bisphosphate B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16115720
NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
G
Ambp
alpha-1-microglobulin/bikunin precursor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18779383
NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331
G
Anxa2
annexin A2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
G
Anxa6
annexin A6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433
G
Apoa1
apolipoprotein A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
G
Apoe
apolipoprotein E
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
G
Apoh
apolipoprotein H
IEP ISO
mRNA:increased expression:plasma: CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16099942 PMID:23288050
RGD:10054107
NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
G
Arg1
arginase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22872058
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
G
Arnt
aryl hydrocarbon receptor nuclear translocator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20935161
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
G
Atg5
autophagy related 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22491424
NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
G
Atoh8
atonal bHLH transcription factor 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
G
Atp6v1d
ATPase H+ transporting V1 subunit D
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303
G
Bad
BCL2-associated agonist of cell death
treatment
IDA
RGD
PMID:25447754
RGD:10053709
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
G
Bax
BCL2 associated X, apoptosis regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17906064
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Bdh1
3-hydroxybutyrate dehydrogenase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
G
Bdkrb2
bradykinin receptor B2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30685357
NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
G
Blvrb
biliverdin reductase B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
G
Bmal1
basic helix-loop-helix ARNT like 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:36602574
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
G
Bpnt1
3'(2'), 5'-bisphosphate nucleotidase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503
G
Brd4
bromodomain containing 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
G
Btd
biotinidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15469856
NCBI chr16:6,863,068...6,894,345
Ensembl chr16:6,862,407...6,940,945
G
C3
complement C3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
G
Cabp1
calcium binding protein 1
IEP
protein:increased expression:liver
RGD
PMID:21138988
RGD:7241599
NCBI chr12:41,385,234...41,448,930
Ensembl chr12:41,378,897...41,448,927
G
Cadps2
calcium dependent secretion activator 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829
G
Canx
calnexin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
G
Cap1
cyclase associated actin cytoskeleton regulatory protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769
G
Car3
carbonic anhydrase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513 PMID:25231249
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
G
Casp8
caspase 8
treatment
IEP
RGD
PMID:25447754
RGD:10053709
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
G
Cast
calpastatin
IEP
RGD
PMID:16871587
RGD:5683869
NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
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Cat
catalase
ISO IEP
CTD Direct Evidence: marker/mechanism protein:decreased expression:liver
CTD RGD
PMID:20623750 PMID:25231249 PMID:21138988
RGD:7241599
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccdc80
coiled-coil domain containing 80
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137
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Ccl2
C-C motif chemokine ligand 2
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20623750 PMID:21813474 PMID:30663942
RGD:14995466 , RGD:14995458
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
G
Ccr2
C-C motif chemokine receptor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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Ccr5
C-C motif chemokine receptor 5
susceptibility
ISO
acetaminophen
RGD
PMID:24770590
RGD:14401733
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
G
Cct3
chaperonin containing TCP1 subunit 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757
G
Cct5
chaperonin containing TCP1 subunit 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
G
Cdc25b
cell division cycle 25B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
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Cds1
CDP-diacylglycerol synthase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681
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Cela1
chymotrypsin like elastase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285
G
Cfap20
cilia and flagella associated protein 20
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr19:9,608,867...9,622,558
Ensembl chr19:9,608,859...9,622,558
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Cfh
complement factor H
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
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Chrm3
cholinergic receptor, muscarinic 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20197374
NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
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Ckb
creatine kinase B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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Clu
clusterin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
G
Col14a1
collagen type XIV alpha 1 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214
G
Col3a1
collagen type III alpha 1 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16679477
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
G
Comt
catechol-O-methyltransferase
IEP
protein:decreased expression:liver
RGD
PMID:21138988
RGD:7241599
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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Coq9
coenzyme Q9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr19:10,166,948...10,179,976
Ensembl chr19:10,166,951...10,179,949
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Cp
ceruloplasmin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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Cpb2
carboxypeptidase B2
IEP
mRNA,protein:increased expression,increased activity:liver,plasma
RGD
PMID:19386599
RGD:7243112
NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
G
Cps1
carbamoyl-phosphate synthase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
G
Cpt1a
carnitine palmitoyltransferase 1A
IEP
mRNA:decreased expression:liver (rat)
RGD
PMID:28959666
RGD:401794432
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
G
Crp
C-reactive protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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Csf3
colony stimulating factor 3
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:20005281 PMID:33882750
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
G
Ctnnb1
catenin beta 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:19679878
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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Ctse
cathepsin E
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502
G
Cxcl1
C-X-C motif chemokine ligand 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16118408
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
G
Cxcl10
C-X-C motif chemokine ligand 10
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:11739529
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
G
Cxcl14
C-X-C motif chemokine ligand 14
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:38614205
NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
G
Cxcl3
C-X-C motif chemokine ligand 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16118408
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33814510
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28762043
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33814510
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
G
Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
ISO
mRNA, protein:decreased expression:kidney (mouse)
RGD
PMID:26476181
RGD:25671412
NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28762043 PMID:33814510
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
G
Cyp2c11
cytochrome P450, subfamily 2, polypeptide 11
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
G
Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12963435 PMID:28762043
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
G
Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
ISO
DNA:hypermethylation:promoter
RGD
PMID:27490558
RGD:14700879
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
treatment
ISO IEP
CTD Direct Evidence: marker/mechanism DNA:hypermethylation:promoter associated with Endotoxemia
CTD RGD
PMID:12668988 PMID:16770646 PMID:21741958 PMID:28762043 PMID:27960551 PMID:27490558 PMID:27324775 PMID:29404441 PMID:25681370 More...
RGD:14700901 , RGD:14700879 , RGD:14700878 , RGD:14700873 , RGD:14700872
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28762043
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
G
Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
G
Cyp4a3
cytochrome P450, family 4, subfamily a, polypeptide 3
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
G
Cyp8b1
cytochrome P450 family 8 subfamily B member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25448281
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
G
Dbt
dihydrolipoamide branched chain transacylase E2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609
G
Ddb1
damage-specific DNA binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676
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Dgat2
diacylglycerol O-acyltransferase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17984051
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
G
Dhfr
dihydrofolate reductase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19648163
NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
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Dhrs7
dehydrogenase/reductase 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
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Dlat
dihydrolipoamide S-acetyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
G
Dnajb9
DnaJ heat shock protein family (Hsp40) member B9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
G
Dnajc12
DnaJ heat shock protein family (Hsp40) member C12
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr20:25,246,744...25,267,508
Ensembl chr20:25,223,144...25,267,521
G
Dsc2
desmocollin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
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E2f1
E2F transcription factor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30515189
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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Echdc1
ethylmalonyl-CoA decarboxylase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319
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Echs1
enoyl-CoA hydratase, short chain 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
G
Edem1
ER degradation enhancing alpha-mannosidase like protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
G
Eif2ak1
eukaryotic translation initiation factor 2 alpha kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25411909
NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573
G
Eif4ebp2
eukaryotic translation initiation factor 4E binding protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,382,668...29,399,946
G
Endog
endonuclease G
IEP
protein:decreased expression:mitochondrion:
RGD
PMID:22509279
RGD:9685364
NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
G
Eng
endoglin
IEP
protein:increased expression:liver (rat)
RGD
PMID:21146604
RGD:7257529
NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
G
Eno1
enolase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942 PMID:25231249
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
G
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
IEP
protein:increased activity:serum:
RGD
PMID:17850827
RGD:9685426
NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
G
Ephx1
epoxide hydrolase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
G
Erlec1
endoplasmic reticulum lectin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr14:104,655,745...104,693,508
Ensembl chr14:104,655,673...104,693,480
G
Ern1
endoplasmic reticulum to nucleus signaling 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30538632
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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F13a1
coagulation factor XIII A1 chain
ISO
RGD
PMID:22019897
RGD:11041813
NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
G
F2rl3
F2R like thrombin or trypsin receptor 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20974703
NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472
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F3
coagulation factor III, tissue factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22407844
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
G
Fadd
Fas associated via death domain
treatment
IEP
RGD
PMID:26062544 PMID:25447754
RGD:11341803 , RGD:10053709
NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
G
Fads1
fatty acid desaturase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
G
Fads2
fatty acid desaturase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
G
Fas
Fas cell surface death receptor
IEP
protein:increased expression:liver (rat)
RGD
PMID:16831245
RGD:8662853
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
G
Fasn
fatty acid synthase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fcmr
Fc mu receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653
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Fga
fibrinogen alpha chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20974703
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
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Fgf21
fibroblast growth factor 21
severity
IEP
mRNA:increased expression:liver (rat)
RGD
PMID:29883717
RGD:15045603
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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Flt1
Fms related receptor tyrosine kinase 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21135413
NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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Fmo3
flavin containing dimethylaniline monoxygenase 3
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:24973094
NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
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Ftl1
ferritin light chain 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
G
G6pc1
glucose-6-phosphatase catalytic subunit 1
ISO
mRNA:decreased expression:liver (mouse)
RGD
PMID:28189721
RGD:14695531
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
G
G6pd
glucose-6-phosphate dehydrogenase
treatment
IEP
RGD
PMID:21864513
RGD:10449168
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Ganab
glucosidase II alpha subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695
G
Gc
GC, vitamin D binding protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
G
Gclc
glutamate-cysteine ligase, catalytic subunit
IMP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:19481141 PMID:17573345
RGD:10402383
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gda
guanine deaminase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
G
Gdi1
GDP dissociation inhibitor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr X:152,087,611...152,094,274
Ensembl chr X:152,087,444...152,094,272
G
Gfer
growth factor, augmenter of liver regeneration
treatment
ISO IDA
RGD
PMID:22033404 PMID:15968720
RGD:9685722 , RGD:9685727
NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869
G
Ggh
gamma-glutamyl hydrolase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21219404
NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
G
Ggt1
gamma-glutamyltransferase 1
IEP
RGD
PMID:10934156
RGD:14701049
NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
G
Ghrl
ghrelin and obestatin prepropeptide
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:34151639
NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
G
Glud1
glutamate dehydrogenase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33483742
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Got1
glutamic-oxaloacetic transaminase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
G
Gpd1
glycerol-3-phosphate dehydrogenase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
G
Gpt
glutamic--pyruvic transaminase
treatment
ISO IEP
CTD Direct Evidence: marker/mechanism protein:increased expression, activity:serum:
CTD RGD
PMID:145039 PMID:19481104 PMID:19085960 PMID:19085960 PMID:27293452 PMID:21772750 PMID:28487901 More...
RGD:14975249 , RGD:14975249 , RGD:14975168 , RGD:14975166 , RGD:14975162
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Gpt2
glutamic--pyruvic transaminase 2
IEP ISO
protein:increased expression, activity:serum:
RGD
PMID:19085960 PMID:19085960
RGD:14975249 , RGD:14975249
NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
G
Grk4
G protein-coupled receptor kinase 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr14:75,998,554...76,080,808
Ensembl chr14:76,006,218...76,080,693
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Gsn
gelsolin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
G
Gsr
glutathione-disulfide reductase
treatment
IEP ISO
mRNA, protein:increased expression:liver CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:25226513 PMID:28069987 PMID:23554813 PMID:24154663
RGD:7257532 , RGD:10401878
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gsta1
glutathione S-transferase alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28412881
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
G
Gsta4
glutathione S-transferase alpha 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
G
Gstm1
glutathione S-transferase mu 1
no_association
ISO IEP
CTD Direct Evidence: marker/mechanism protein:increased expression:liver
CTD RGD
PMID:17465707 PMID:18666253 PMID:25501156 PMID:24465778 PMID:24903797 PMID:29523098 PMID:21138988 More...
RGD:14700970 , RGD:14700959 , RGD:14700941 , RGD:14700937 , RGD:7241599
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
G
Gstm2
glutathione S-transferase mu 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
G
Gstm4
glutathione S-transferase mu 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
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Gstm5
glutathione S-transferase, mu 5
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:25743375
NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
G
Gsto1
glutathione S-transferase omega 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
G
Gstp1
glutathione S-transferase pi 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750 PMID:25226513
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Gstt1
glutathione S-transferase theta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18397238 PMID:18666253 PMID:25226513
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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H19
H19 imprinted maternally expressed transcript
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30515189
NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
G
H2ax
H2A.X variant histone
treatment
IDA
RGD
PMID:23265463
RGD:8693741
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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Hacl1
2-hydroxyacyl-CoA lyase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027
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Hadha
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
G
Hamp
hepcidin antimicrobial peptide
IEP
mRNA:increased expression:hepatocyte
RGD
PMID:24373749
RGD:11041724
NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
G
Hao2
hydroxyacid oxidase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
G
Havcr1
hepatitis A virus cellular receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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Hba-a1
hemoglobin alpha, adult chain 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392
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Hmgb1
high mobility group box 1
treatment
ISO IEP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:19783637 PMID:29091898
RGD:15090820
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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Hmox1
heme oxygenase 1
treatment
IEP ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD RGD
PMID:18227147 PMID:22688006 PMID:22886620 PMID:29091898
RGD:10762620 , RGD:15090820
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hpd
4-hydroxyphenylpyruvate dioxygenase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942 PMID:22872058
NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
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Hpx
hemopexin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
G
Hrh2
histamine receptor H 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22926047
NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631
G
Hspa5
heat shock protein family A (Hsp70) member 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
G
Hspa8
heat shock protein family A (Hsp70) member 8
IEP
protein:altered localization:liver (rat)
RGD
PMID:12376827
RGD:10059389
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
G
Icam1
intercellular adhesion molecule 1
treatment
IEP
RGD
PMID:29091898
RGD:15090820
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
G
Idh2
isocitrate dehydrogenase (NADP(+)) 2
severity
ISO
RGD
PMID:31121248
RGD:14985250
NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
G
Ido2
indoleamine 2,3-dioxygenase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32289347
NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
G
Ifng
interferon gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12153990 PMID:21245496 PMID:30013034
RGD:14975100
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
G
Igf1
insulin-like growth factor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23639586 PMID:25226513
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
G
Il11
interleukin 11
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:11421492
NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
G
Il12b
interleukin 12B
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:36520315
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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Il17a
interleukin 17A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19633216 PMID:24949944
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
G
Il18
interleukin 18
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19164858
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
G
Il1a
interleukin 1 alpha
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:8218930
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1b
interleukin 1 beta
treatment
IDA IEP ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD RGD
PMID:19164858 PMID:28138970 PMID:23102243 PMID:29091898 PMID:31342809 PMID:31077717 PMID:29278859 More...
RGD:7204421 , RGD:15090820 , RGD:15036799 , RGD:14975281 , RGD:13793380
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il1r2
interleukin 1 receptor type 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17984051
NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
G
Il22
interleukin 22
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15122762 PMID:16212920 PMID:23375450
NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186
G
Il4
interleukin 4
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:21094227 PMID:21735453 PMID:22107450
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il6
interleukin 6
treatment
ISO IEP
CTD Direct Evidence: therapeutic
CTD RGD
PMID:7532385 PMID:15763341 PMID:29091898
RGD:15090820
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Immt
inner membrane mitochondrial protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109
G
Irak1
interleukin-1 receptor-associated kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
G
Itpr1
inositol 1,4,5-trisphosphate receptor, type 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
G
Jund
JunD proto-oncogene, AP-1 transcription factor subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30515189
NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
G
Keap1
Kelch-like ECH-associated protein 1
ISO
RGD
PMID:18417483
RGD:6893370
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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Kitlg
KIT ligand
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:12594235
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
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Kng1
kininogen 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20362651 PMID:30685357
NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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Krt18
keratin 18
ISO
mRNA, protein:increased expression:liver (mouse) CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:19783637 PMID:33483742 PMID:38521541 PMID:17340120
RGD:18337498
NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
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Krt8
keratin 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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Lap3
leucine aminopeptidase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359
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Lbp
lipopolysaccharide binding protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
G
Lcat
lecithin cholesterol acyltransferase
IEP
mRNA:decreased expression:liver (rat)
RGD
PMID:28959666
RGD:401794432
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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Lcn2
lipocalin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20362651 PMID:20623750
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
G
Ldlr
low density lipoprotein receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:36108984
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Lgals3
galectin 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22461450
NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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Lipc
lipase C, hepatic type
IEP
mRNA:decreased expression:liver (rat)
RGD
PMID:28959666
RGD:401794432
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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Lpl
lipoprotein lipase
treatment
IEP
RGD
PMID:27071702
RGD:13794380
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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Lrat
lecithin retinol acyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
G
Ltb4r
leukotriene B4 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28487374
NCBI chr15:29,263,199...29,265,716
G
Ltf
lactotransferrin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:16141546
NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
G
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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Map3k5
mitogen-activated protein kinase kinase kinase 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18700144
NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
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Mat1a
methionine adenosyltransferase 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
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Mccc1
methylcrotonyl-CoA carboxylase subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222
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Mdh1
malate dehydrogenase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
G
Me1
malic enzyme 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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Med1
mediator complex subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16109766
NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
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Mir100
microRNA 100
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304
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Mir103a1
microRNA 103a-1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr10:20,244,412...20,244,497
Ensembl chr10:20,244,412...20,244,497
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Mir106b
microRNA 106b
IEP IDA
miRNA:decreased expression:liver (rat) DNA:hypermethylation:promoter
RGD
PMID:29554950 PMID:29554950
RGD:15042854 , RGD:15042854
NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425
G
Mir107
microRNA 107
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25359176 PMID:28545106
NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853
G
Mir10a
microRNA 10a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280
G
Mir10b
microRNA 10b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546
G
Mir122
microRNA 122
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22045675 PMID:22363424 PMID:25359176 PMID:25527335 PMID:26489516 PMID:28545106 PMID:28844483 PMID:33483742 More...
NCBI chr18:58,758,703...58,758,787
G
Mir1249
microRNA 1249
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 7:116,075,593...116,075,712
Ensembl chr 7:116,075,593...116,075,712
G
Mir125b1
microRNA 125b-1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
G
Mir125b2
microRNA 125b-2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:16,245,620...16,245,707
G
Mir1306
microRNA 1306
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:82,709,651...82,709,723
Ensembl chr11:82,709,637...82,709,719
G
Mir130a
microRNA 130a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25359176 PMID:28545106
NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
G
Mir130b
microRNA 130b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244
G
Mir132
microRNA 132
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796
G
Mir141
microRNA 141
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424 PMID:28545106
NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
G
Mir142
microRNA 142
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
G
Mir143
microRNA 143
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30125006
NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
G
Mir148a
microRNA 148a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25359176 PMID:28545106
NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858
G
Mir150
microRNA 150
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108
G
Mir151b
microRNA 151b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 7:105,172,377...105,172,496
Ensembl chr 7:105,172,377...105,172,496
G
Mir152
microRNA 152
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
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Mir155
microRNA 155
treatment
ISO
RGD
PMID:29420849 PMID:26867493 PMID:27673475
RGD:21409750 , RGD:25671474 , RGD:25671463
NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
G
Mir17
microRNA 17
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
G
Mir181c
microRNA 181c
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
G
Mir188
microRNA 188
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:15,247,715...15,247,794
Ensembl chr X:15,247,715...15,247,794
G
Mir18a
microRNA 18a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
G
Mir191
microRNA 191
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 8:109,264,098...109,264,188
G
Mir192
microRNA 192
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22045675 PMID:25359176 PMID:28483554 PMID:28545106
NCBI chr 1:203,564,946...203,565,055
Ensembl chr 1:203,564,946...203,565,055
G
Mir193a
microRNA 193a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454
G
Mir193b
microRNA 193b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr10:1,317,742...1,317,824
Ensembl chr10:1,317,742...1,317,824
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Mir194-1
microRNA 194-1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28844483
NCBI chr13:96,851,166...96,851,248
Ensembl chr13:96,851,166...96,851,248
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Mir19a
microRNA 19a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
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Mir1b
microRNA 1b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30125006
NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201
G
Mir200c
microRNA 200c
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 4:157,523,679...157,523,747
G
Mir21
microRNA 21
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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Mir210
microRNA 210
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
G
Mir217
microRNA 217
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr14:102,531,505...102,531,609
Ensembl chr14:102,531,505...102,531,609
G
Mir22
microRNA 22
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25359176 PMID:28545106
NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133
G
Mir221
microRNA 221
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573
G
Mir222
microRNA 222
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006
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Mir223
microRNA 223
ISO
RNA:increased expression:serum,liver
RGD
PMID:28646120
RGD:21408574
NCBI chr X:61,141,887...61,141,996
Ensembl chr X:61,141,887...61,141,996
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Mir23a
microRNA 23a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071
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Mir23b
microRNA 23b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763
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Mir27b
microRNA 27b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25359176 PMID:28545106
NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
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Mir29b2
microRNA 29b-2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456
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Mir301a
microRNA 301a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435
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Mir30a
microRNA 30a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424 PMID:25359176 PMID:28545106
NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
G
Mir30b
microRNA 30b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675
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Mir30c1
microRNA 30c-1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325
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Mir320a
microRNA 320a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106 PMID:30125006
NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
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Mir328
microRNA 328
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr19:33,184,766...33,184,849
Ensembl chr19:33,184,766...33,184,849
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Mir337
microRNA 337
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 6:128,538,903...128,538,999
Ensembl chr 6:128,538,902...128,538,998
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Mir342
microRNA 342
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
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Mir345
microRNA 345
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122
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Mir34a
microRNA 34a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
G
Mir34c
microRNA 34c
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802
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Mir3545
microRNA 3545
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:32659284
NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656
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Mir361
microRNA 361
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:78,246,206...78,246,275
Ensembl chr X:78,246,206...78,246,275
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Mir410
microRNA 410
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 6:128,758,358...128,758,433
Ensembl chr 6:128,758,354...128,758,434
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Mir423
microRNA 423
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
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Mir455
microRNA 455
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390
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Mir484
microRNA 484
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr10:887,684...887,760
Ensembl chr10:887,684...887,760
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Mir497
microRNA 497
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
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Mir499a
microRNA 499a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 3:144,110,469...144,110,533
Ensembl chr 3:144,110,469...144,110,533
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Mir503
microRNA 503
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr X:132,806,303...132,806,373
Ensembl chr X:132,806,303...132,806,373
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Mir532
microRNA 532
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:15,247,315...15,247,393
Ensembl chr X:15,247,315...15,247,393
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Mir592
microRNA 592
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424 PMID:28545106
NCBI chr 4:56,505,280...56,505,375
Ensembl chr 4:56,505,280...56,505,375
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Mir764
microRNA 764
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr X:110,678,597...110,678,704
Ensembl chr X:110,678,597...110,678,704
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Mir877
microRNA 877
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27713024
NCBI chr20:2,811,476...2,811,560
Ensembl chr20:2,811,476...2,811,560
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Mir93
microRNA 93
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
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Mir99a
microRNA 99a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523
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Mirlet7b
microRNA let-7b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106 PMID:30125006
NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270
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Mirlet7c1
microRNA let-7c-1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265
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Mirlet7d
microRNA let-7d
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:16,115,893...16,115,990
Ensembl chr17:16,115,893...16,115,990
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Mirlet7g
microRNA let-7g
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388
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Mirlet7i
microRNA let-7i
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571
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Mmp2
matrix metallopeptidase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15763341
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp9
matrix metallopeptidase 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22507835
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mst1
macrophage stimulating 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416
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Mst1r
macrophage stimulating 1 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22575169
NCBI chr 8:108,596,100...108,611,441
Ensembl chr 8:108,597,299...108,612,455
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Mt-nd6
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
IEP
mRNA:decreased expression:blood
RGD
PMID:20130021
RGD:8657129
NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
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Mthfr
methylenetetrahydrofolate reductase
treatment
ISO
CTD Direct Evidence: marker/mechanism associated with precursor lymphoblastic lymphoma/leukemia; DNA:SNP: :677C>T(human)
CTD RGD
PMID:18551038 PMID:19648163 PMID:30545275
RGD:14696733
NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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Mtpn
myotrophin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724
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Mug2
murinoglobulin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
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Myd88
MYD88, innate immune signal transduction adaptor
ameliorates
ISO
RGD
PMID:17615358
RGD:150521532
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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Nat2
N-acetyltransferase 2
treatment
ISO
associated with Tuberculosis;DNA:haplotype: : CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:11915035 PMID:16799928 PMID:17950035 PMID:25693865 PMID:18023090
RGD:8552665
NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
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Ndufs3
NADH:ubiquinone oxidoreductase core subunit S3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824
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Nfatc4
nuclear factor of activated T-cells 4
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:34192554
NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
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Nfe2l2
NFE2 like bZIP transcription factor 2
treatment
ISO IEP
induced by methotrexate (CHEBI:44185), treated by ferulic acid (CHEBI:17620) CTD Direct Evidence: therapeutic
CTD RGD
PMID:22491424 PMID:22627062 PMID:24813929 PMID:26958860 PMID:30215777 PMID:18417483 PMID:31889292 PMID:31927046 PMID:32066295 PMID:31972209 PMID:29091898 More...
RGD:6893370 , RGD:21201308 , RGD:21201305 , RGD:21201283 , RGD:21201280 , RGD:15090820
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkb1
nuclear factor kappa B subunit 1
treatment susceptibility
IEP ISO
associated with tuberculosis ;DNA:SNPs,haplotypes: 3'utr,5'utr: (rs78872571,rs4647992) (human)
RGD
PMID:29091898 PMID:31490979
RGD:15090820 , RGD:40902984
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nfxl1
nuclear transcription factor, X-box binding-like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr14:35,626,086...35,667,505
Ensembl chr14:35,626,066...35,667,498
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Nme2
NME/NM23 nucleoside diphosphate kinase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
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Notch1
notch receptor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:30394310
NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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Nox4
NADPH oxidase 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
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Nqo1
NAD(P)H quinone dehydrogenase 1
treatment
IDA IEP ISO
RGD
PMID:28522909 PMID:29091898 PMID:28472605
RGD:13439737 , RGD:15090820 , RGD:13439739
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr0b2
nuclear receptor subfamily 0, group B, member 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:29943110
NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
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Nr1d1
nuclear receptor subfamily 1, group D, member 1
treatment
ISO
RGD
PMID:24497272
RGD:10448995
NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
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Nr1h3
nuclear receptor subfamily 1, group H, member 3
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17256725
NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
treatment severity
ISO IEP
CTD Direct Evidence: marker/mechanism mRNA:decreased expression:liver (rat) protein:decreased expression:liver (rat)
CTD RGD
PMID:12875239 PMID:29091898 PMID:28827769 PMID:30068870 PMID:22711662 PMID:20573685 More...
RGD:15090820 , RGD:15045609 , RGD:15042870 , RGD:14701036 , RGD:14701035
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
susceptibility
ISO
CTD Direct Evidence: marker/mechanism|therapeutic associated with tuberculosis ;DNA:SNP,haplotypes:promoter: (rs3814055) (human)
CTD RGD
PMID:19797606 PMID:28058446 PMID:31490979
RGD:40902984
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:14742670 PMID:25656644 PMID:28058446
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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Nr2f2
nuclear receptor subfamily 2, group F, member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
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Nr5a2
nuclear receptor subfamily 5, group A, member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29515023
NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326
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Nrep
neuronal regeneration related protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
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Ntn1
netrin 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:35292334
NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
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Nus1
NUS1 dehydrodolichyl diphosphate synthase subunit
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:33812996
NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
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Obp3
alpha-2u globulin PGCL4
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
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Ociad1
OCIA domain containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr14:34,897,851...34,915,291
Ensembl chr14:34,897,847...34,915,286
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Ogdh
oxoglutarate dehydrogenase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
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Olr59
olfactory receptor 59
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
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P4hb
prolyl 4-hydroxylase subunit beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
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Pah
phenylalanine hydroxylase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
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Pan2
poly(A) specific ribonuclease subunit PAN2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 7:729,146...747,744
Ensembl chr 7:729,562...747,744
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Panx1
Pannexin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29246445
NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774
G
Park7
Parkinsonism associated deglycase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
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Pc
pyruvate carboxylase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
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Pcolce
procollagen C-endopeptidase enhancer
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508
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Pcyt1a
phosphate cytidylyltransferase 1A, choline
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357
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Pdk4
pyruvate dehydrogenase kinase 4
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:21182459 PMID:31809757
NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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Pdlim5
PDZ and LIM domain 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
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Pex11a
peroxisomal biogenesis factor 11 alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
G
Pgm1
phosphoglucomutase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728
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Plat
plasminogen activator, tissue type
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22507835
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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Plg
plasminogen
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22507835
NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
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Pls3
plastin 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr X:111,589,193...111,683,908
Ensembl chr X:111,589,254...111,683,891
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Pnp
purine nucleoside phosphorylase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986
G
Pnrc1
proline-rich nuclear receptor coactivator 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161
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Polg
DNA polymerase gamma, catalytic subunit
susceptibility no_association
ISO IAGP
CTD Direct Evidence: marker/mechanism DNA:missense mutation:cds:p.W748S, p.E1143G (2243G>C, 3428A>G) (human) DNA:missense mutations:cds:p.Q1236H, p.E1143G (33708G>T, 3428A>G) (human)
CTD RGD
PMID:18208989 PMID:20138553 PMID:25065347 PMID:30255931
RGD:15039302 , RGD:15039297
NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567
G
Polr2g
RNA polymerase II subunit G
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:205,689,160...205,692,537
Ensembl chr 1:205,689,160...205,692,686
G
Pon1
paraoxonase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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Ppara
peroxisome proliferator activated receptor alpha
ISO
LPS-induced acute liver damage CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:24385052 PMID:38181850 PMID:21262334
RGD:5509941
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Pparg
peroxisome proliferator-activated receptor gamma
ISO
mRNA, protein:decreased expression:liver
RGD
PMID:26599535
RGD:11554658
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Pptc7
protein phosphatase targeting COQ7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr12:34,249,963...34,288,339
Ensembl chr12:34,249,977...34,288,339
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Prkaa1
protein kinase AMP-activated catalytic subunit alpha 1
treatment
IEP
RGD
PMID:29091898
RGD:15090820
NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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Prkcd
protein kinase C, delta
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:30393195
NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
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Prkdc
protein kinase, DNA-activated, catalytic subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21224054
NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
G
Ptf1a
pancreas associated transcription factor 1a
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21182459
NCBI chr17:82,051,281...82,053,135
Ensembl chr17:82,051,281...82,053,135
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Ptges2
prostaglandin E synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:31444509
NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
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Ptgs2
prostaglandin-endoperoxide synthase 2
treatment
ISO IEP
CTD Direct Evidence: therapeutic
CTD RGD
PMID:11743745 PMID:29091898
RGD:15090820
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Pum1
pumilio RNA-binding family member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 5:142,836,933...142,954,331
Ensembl chr 5:142,837,127...142,954,039
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Pygl
glycogen phosphorylase L
ISO IEP
CTD Direct Evidence: marker/mechanism protein:increased expression:serum (rat)
CTD RGD
PMID:25231249 PMID:25336395
RGD:21079733
NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
G
Rasa1
RAS p21 protein activator 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
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Rbp1
retinol binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
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Rdh13
retinol dehydrogenase 13
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27865848
NCBI chr 1:69,373,014...69,401,454
Ensembl chr 1:69,373,113...69,400,908
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Reep5
receptor accessory protein 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr18:25,945,375...25,983,271
Ensembl chr18:25,945,381...25,976,509
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Rgn
regucalcin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450
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Ripk3
receptor-interacting serine-threonine kinase 3
ISO
CTD Direct Evidence: therapeutic protein:increased expression:liver (mouse)
CTD RGD
PMID:26769846 PMID:28205631
RGD:127229945
NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
G
RT1-Ba
RT1 class II, locus Ba
susceptibility
ISO
DNA:polymorphism: :HLA-DQA1*0102(human) associated with tuberculosis;DNA:polymorphism: :HLA-DQA1*0102(human)
RGD
PMID:20639878 PMID:12359646
RGD:14398844 , RGD:14401573
NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
G
RT1-Bb
RT1 class II, locus Bb
susceptibility
ISO
CTD Direct Evidence: marker/mechanism DNA:polymorphism: :HLA-DQB1*05(human) DNA:polymorphism, haplotype
CTD RGD
PMID:21570397 PMID:25250564 PMID:26959717
RGD:36174016 , RGD:11573514
NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
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RT1-CE16
RT1 class I, locus CE16
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21570397 PMID:28043905
NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
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RT1-Db1
RT1 class II, locus Db1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21570397
NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
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S100a11
S100 calcium binding protein A11
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
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Scarb1
scavenger receptor class B, member 1
IEP
mRNA:increased expression:liver (rat)
RGD
PMID:28959666
RGD:401794432
NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
G
Selenbp1
selenium binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594
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Sema3a
semaphorin 3A
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:33290778
NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432
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Sema4a
semaphorin 4A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33290778
NCBI chr 2:173,896,432...173,917,903
Ensembl chr 2:173,896,439...173,914,442
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Senp2
SUMO specific peptidase 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:29535048
NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238
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Serpina1
serpin family A member 1
susceptibility
IEP ISO
protein:decreased expression:plasma DNA:missense mutation:cds:p.E264V(human)
RGD
PMID:11140575 PMID:20170533
RGD:1643168 , RGD:14695048
NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
G
Serpina6
serpin family A member 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:122,780,043...122,790,349
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Serpine1
serpin family E member 1
treatment
ISO
associated with precursor lymphoblastic lymphoma/leukemia;DNA:SNPs: :DNA:SNPs: :677C>T, 1298A>C(human)
RGD
PMID:23183238
RGD:14696750
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Serping1
serpin family G member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
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Sesn2
sestrin 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:28209544
NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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Sgf29
SAGA complex associated factor 29
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:181,238,458...181,271,931
Ensembl chr 1:181,238,468...181,274,781
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Shc1
SHC adaptor protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249 PMID:32659284
NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
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Slc10a1
solute carrier family 10 member 1
IEP
mRNA:decreased expression:liver (rat)
RGD
PMID:28827769
RGD:15045609
NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
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Slc10a7
solute carrier family 10, member 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr19:29,183,143...29,407,470
Ensembl chr19:29,183,155...29,407,464
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Slc13a4
solute carrier family 13 member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 4:63,943,369...63,988,852
Ensembl chr 4:63,943,395...63,988,857
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Slc22a8
solute carrier family 22 member 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
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Slc25a29
solute carrier family 25 member 29
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940
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Slc7a5
solute carrier family 7 member 5
treatment
IEP
RGD
PMID:9200186
RGD:151357001
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
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Slpi
secretory leukocyte peptidase inhibitor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17984051
NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
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Snx18
sorting nexin 18
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17984051
NCBI chr 2:45,232,325...45,258,345
Ensembl chr 2:45,232,325...45,258,345
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Sod1
superoxide dismutase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750 PMID:27349771
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sod2
superoxide dismutase 2
treatment severity susceptibility
ISO IMP
CTD Direct Evidence: marker/mechanism associated with acute lymphoblastic leukemia;DNA:SNP: :(rs4880)(human) DNA:SNP:cds:p.Val16Ala(human)
CTD RGD
PMID:25226513 PMID:27019981 PMID:19647030 PMID:19332662 PMID:20578157
RGD:11060605 , RGD:26923961 , RGD:26923959 , RGD:26923957
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sod3
superoxide dismutase 3
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:11529661
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
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Sord
sorbitol dehydrogenase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12763371
NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
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Sorl1
sortilin related receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
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Spin2a
spindlin family member 2A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr X:17,511,018...17,513,001
Ensembl chr X:17,511,022...17,513,001
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Spp1
secreted phosphoprotein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Srp72
signal recognition particle 72
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729
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Stat3
signal transducer and activator of transcription 3
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:38460807
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Stat4
signal transducer and activator of transcription 4
severity
ISO
protein:increased phosphorylation:liver, inflammatory cell (mouse) mRNA:increased expression:liver, macrophage (mouse)
RGD
PMID:24731448 PMID:23876342
RGD:25671417 , RGD:25671422
NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540
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Sting1
stimulator of interferon response cGAMP interactor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:36520315
NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335
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Sult1c3
sulfotransferase family 1C member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
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Sult1e1
sulfotransferase family 1E member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
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Sult2b1
sulfotransferase family 2B member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27052460
NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295
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Suox
sulfite oxidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038
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Tagln2
transgelin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972
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Taldo1
transaldolase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19436114
NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
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Tbxa2r
thromboxane A2 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22206755
NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
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Tctn1
tectonic family member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17984051
NCBI chr12:34,309,795...34,347,190
Ensembl chr12:34,309,897...34,342,267
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Tf
transferrin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
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Tgfb1
transforming growth factor, beta 1
treatment
ISO
RGD
PMID:27516150
RGD:14995464
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfbr1
transforming growth factor, beta receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28560358
NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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Thbs1
thrombospondin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:35357534
NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
G
Thpo
thrombopoietin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:33122006
Ensembl chr11:80,182,820...80,188,167
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Tlr4
toll-like receptor 4
disease_progression
IEP
RGD
PMID:17504260
RGD:14697733
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tlr5
toll-like receptor 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30508503
NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738
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Tlr9
toll-like receptor 9
severity treatment
ISO
protein:increased expression: blood, neutrophil (human)
RGD
PMID:26457748 PMID:19164858 PMID:23509352
RGD:18337465 , RGD:18337476 , RGD:18337473
NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
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Tmed7
transmembrane p24 trafficking protein 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
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Tmem117
transmembrane protein 117
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 7:125,757,591...126,219,692
Ensembl chr 7:125,757,591...126,219,690
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Tmem164
transmembrane protein 164
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr X:106,288,019...106,448,642
Ensembl chr X:106,289,371...106,448,640
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Tmem38b
transmembrane protein 38B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 5:68,460,304...68,496,026
Ensembl chr 5:68,460,304...68,496,025
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Tnf
tumor necrosis factor
treatment severity
IDA ISO IEP IMP
CTD Direct Evidence: marker/mechanism|therapeutic protein:increased expression:serum (rat)
CTD RGD
PMID:7532385 PMID:9696492 PMID:17709330 PMID:19638433 PMID:20623750 PMID:21984482 PMID:37866487 PMID:15830285 PMID:29091898 PMID:31342809 PMID:14686721 PMID:10801288 PMID:10801287 PMID:9309314 PMID:17070847 PMID:31077717 PMID:11124822 More...
RGD:10450531 , RGD:15090820 , RGD:15036799 , RGD:14995485 , RGD:14995437 , RGD:14995435 , RGD:14995432 , RGD:14995429 , RGD:14975281 , RGD:14696804
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Trpm2
transient receptor potential cation channel, subfamily M, member 2
ISO
RGD
PMID:24569808
RGD:9999438
NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
G
Ttr
transthyretin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
G
Tuba1a
tubulin, alpha 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
G
Tubb4b
tubulin, beta 4B class IVb
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
G
Uba5
ubiquitin-like modifier activating enzyme 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 8:104,665,241...104,680,915
Ensembl chr 8:104,665,046...104,680,894
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
susceptibility
ISO
DNA:SNP:exon (rs4148323)(human)
RGD
PMID:28900877
RGD:14694824
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a9
UDP glucuronosyltransferase family 1 member A9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Unc93b1
unc-93 homolog B1, TLR signaling regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338
G
Usp5
ubiquitin specific peptidase 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711
G
Ust5r
integral membrane transport protein UST5r
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:205,210,558...205,286,868
Ensembl chr 1:205,211,034...205,286,718
G
Vegfa
vascular endothelial growth factor A
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:25231249 PMID:17784864
RGD:15003197
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
G
Vim
vimentin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
G
Vwf
von Willebrand factor
IEP ISO
protein:increased expression:liver: CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:28527913 PMID:7531171
RGD:11079232
NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
G
Wasl
WASP like actin nucleation promoting factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 4:53,083,536...53,132,061
Ensembl chr 4:53,083,536...53,132,022
G
Xrcc1
X-ray repair cross complementing 1
susceptibility
ISO
DNA:haploinsufficiency: : (mouse)
RGD
PMID:21737425
RGD:15036796
NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
G
Xylb
xylulokinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 8:119,093,466...119,128,858
Ensembl chr 8:119,096,029...119,128,848
G
Zdhhc23
zinc finger DHHC-type palmitoyltransferase 23
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
G
Arrb2
arrestin, beta 2
IEP
protein:increased expression:striatum
RGD
PMID:26174132
RGD:11534754
NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
G
Drd2
dopamine receptor D2
IEP
RGD
PMID:26174132
RGD:11534754
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
G
Gad1
glutamate decarboxylase 1
susceptibility
ISO IEP
associated with amphetamine abuse; DNA:haplotype: :rs769404���rs701492(human) protein:decreased expression:prefrontal cortex
RGD
PMID:27967329 PMID:24200867
RGD:401900122 , RGD:401900162
NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
G
Gad2
glutamate decarboxylase 2
susceptibility
ISO
associated with amphetamine abuse; DNA:SNP: :rs2236418(human)
RGD
PMID:27967329
RGD:401900122
NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
G
Oprm1
opioid receptor, mu 1
ISO
associated with amphetamine abuse;DNA:SNP:intron:IVS2+691G>C (human)
RGD
PMID:16402083
RGD:401827939
NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
G
Abat
4-aminobutyrate aminotransferase
IMP
RGD
PMID:7740056 PMID:6445277
RGD:1598524 , RGD:10047091
NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
G
Cacna1d
calcium voltage-gated channel subunit alpha1 D
IMP
RGD
PMID:18947822
RGD:6906919
NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
G
Cat
catalase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19109989
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Cck
cholecystokinin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:2320253
NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
G
Comt
catechol-O-methyltransferase
IMP
RGD
PMID:16437585
RGD:2289781
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
G
Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
ISO
RGD
PMID:1673290
RGD:1358547
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
G
Dbn1
drebrin 1
IEP
levodopainduced; protein:increased expression:striatum:
RGD
PMID:23241013
RGD:10398811
NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
G
Ddc
dopa decarboxylase
IEP
associated with Parkinson Disease; protein:decreased expression:striatum (rat)
RGD
PMID:20232137
RGD:5128860
NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
G
Drd1
dopamine receptor D1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:7845605 PMID:10858612 PMID:16982285 PMID:19520364
NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
G
Drd2
dopamine receptor D2
IDA ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:7845605 PMID:10534246 PMID:14629710 PMID:18707801
RGD:2311579
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
G
Drd3
dopamine receptor D3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20945430
NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
G
Egr1
early growth response 1
IEP
RGD
PMID:22153973
RGD:10395307
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
G
Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17219962
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
G
Gad1
glutamate decarboxylase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9767399
NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
G
Gch1
GTP cyclohydrolase 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15659429
NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
G
Gdnf
glial cell derived neurotrophic factor
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:11168568
NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
G
Glul
glutamate-ammonia ligase
IDA
RGD
PMID:6445277
RGD:10047091
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
G
Grk6
G protein-coupled receptor kinase 6
IMP
associated with Parkinson Disease
RGD
PMID:20410529
RGD:5684919
NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644
G
Gsk3b
glycogen synthase kinase 3 beta
treatment
IMP
associated with Parkinsonian Disorders
RGD
PMID:26997328
RGD:13792768
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
G
Homer1
homer scaffold protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24126708
NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
G
Htr1a
5-hydroxytryptamine receptor 1A
IMP
RGD
PMID:21352823
RGD:5683628
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
G
Mapt
microtubule-associated protein tau
treatment
IDA
associated with Parkinsonian Disorders
RGD
PMID:25511986
RGD:13800920
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
G
Mtor
mechanistic target of rapamycin kinase
treatment
IMP
associated with Parkinsonian Disorders
RGD
PMID:23938307
RGD:10040953
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
G
Pdyn
prodynorphin
treatment severity
ISO IEP HEP
CTD Direct Evidence: marker/mechanism associated with Parkinsonism associated with Parkinsonism;protein:increased expression:striatum
CTD RGD
PMID:9767399 PMID:21737418 PMID:10869049 PMID:17884291 PMID:21737418
RGD:401900134 , RGD:401851046 , RGD:401850563
NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
G
Penk
proenkephalin
treatment disease_progression
IEP ISO
mRNA:increased expression:brain:striatum: associated with Parkinsonism associated with Parkinsonism;mRNA:increased expression:striatum CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:9767399 PMID:20456008 PMID:10869049 PMID:26113400
RGD:10003039 , RGD:401900134 , RGD:401851054
NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
G
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
treatment
IDA
associated with Parkinsonian Disorders
RGD
PMID:27771532
RGD:13514053
NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
G
Rasgrf1
RAS protein-specific guanine nucleotide-releasing factor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21115823
NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269
G
Rela
RELA proto-oncogene, NF-kB subunit
IEP
protein:increased expression:nucleus, brain
RGD
PMID:18590723
RGD:2298778
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Rgs4
regulator of G-protein signaling 4
treatment
IMP
associated with Parkinsonian Disorders
RGD
PMID:24969021
RGD:13524515
NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
G
Rgs9
regulator of G-protein signaling 9
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:18160641 PMID:24663062
NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892
G
Th
tyrosine hydroxylase
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15659429
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
G
Abcc2
ATP binding cassette subfamily C member 2
susceptibility no_association
ISO
DNA:polymorphisms,haplotype:promoter:g.-1774delG,g.-1549G>A(human) DNA:SNPs:multiple:
RGD
PMID:17502832 PMID:22178260
RGD:14700816 , RGD:14700817
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
IDA
DNA:hypermethylation:promoter
RGD
PMID:23619520
RGD:14700910
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
IDA
RGD
PMID:16140414
RGD:2316848
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
G
Lpar1
lysophosphatidic acid receptor 1
ISO
protein:increased expression:liver (mouse)
RGD
PMID:12201952
RGD:10054288
NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
G
Mir22
microRNA 22
ISO
in male; RNA:increased expression:liver:
RGD
PMID:21750200
RGD:14700876
NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133
G
Abcd1
ATP binding cassette subfamily D member 1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,428,334...151,450,115
Ensembl chr X:151,428,578...151,450,115
G
Arhgap4
Rho GTPase activating protein 4
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,636,071...151,651,528
Ensembl chr X:151,632,454...151,651,128
G
Atp2b3
ATPase plasma membrane Ca2+ transporting 3
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:151,216,483...151,289,069
Ensembl chr X:151,216,507...151,286,775
G
Atp6ap1
ATPase H+ transporting accessory protein 1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,079,954...152,087,034
Ensembl chr X:152,079,865...152,087,034
G
Avpr2
arginine vasopressin receptor 2
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,633,501...151,636,155
Ensembl chr X:151,633,522...151,635,989
G
Bcap31
B-cell receptor-associated protein 31
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,397,567...151,429,666
Ensembl chr X:151,397,576...151,428,506
G
Bgn
biglycan
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461
G
Brcc3
BRCA1/BRCA2-containing complex subunit 3
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080
G
Ccnq
cyclin Q
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr10:63,646,532...63,647,695
Ensembl chr10:63,646,527...63,647,961
G
Clic2
chloride intracellular channel 2
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr20:149,337...164,375
Ensembl chr20:148,907...164,355
G
Cmc4
C-X9-C motif containing 4
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr18:125,308...132,163
Ensembl chr18:125,227...132,160
G
Ctag2
cancer/testis antigen 2
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:143,531,907...143,533,201
Ensembl chr X:143,531,907...143,533,201
G
Dkc1
dyskerin pseudouridine synthase 1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
G
Dnase1l1
deoxyribonuclease 1-like 1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,056,942...152,065,518
Ensembl chr X:152,056,942...152,065,518
G
Dusp9
dual specificity phosphatase 9
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:151,351,897...151,355,822
Ensembl chr X:151,351,897...151,355,821
G
Emd
emerin
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,038,990...152,042,190
Ensembl chr X:152,038,998...152,045,807
G
F8
coagulation factor VIII
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
G
F8a1
coagulation factor VIII-associated 1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:150,957,357...150,958,871
Ensembl chr X:150,916,679...150,960,168
G
Fam3a
FAM3 metabolism regulating signaling molecule A
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,166,716...152,175,327
Ensembl chr X:152,165,535...152,175,362
G
Fam50a
family with sequence similarity 50, member A
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,095,245...152,102,362
Ensembl chr X:152,095,245...152,102,362
G
Flna
filamin A
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052
G
Fundc2
FUN14 domain containing 2
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345
G
G6pd
glucose-6-phosphate dehydrogenase
ISO ISS
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency | ClinVar Annotator: match by term: FAVISM, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Favism, susceptibility to | ClinVar Annotator: match by term: G6PD A- | ClinVar Annotator: match by term: G6PD AURES | ClinVar Annotator: match by term: G6PD MALAGA | ClinVar Annotator: match by term: G6PD MINNESOTA | ClinVar Annotator: match by term: G6PD SANTIAGO | ClinVar Annotator: match by term: G6PD SANTIAGO DE CUBA | ClinVar Annotator: match by term: G6PD SERRES
CTD ClinVar MouseDO OMIM
PMID:5448 PMID:16832 PMID:511159 PMID:736032 PMID:835572 PMID:848857 PMID:853376 PMID:1008056 PMID:1270075 PMID:1303173 PMID:1303182 PMID:1459579 PMID:1536798 PMID:1551674 PMID:1562739 PMID:1611091 PMID:1631957 PMID:1805484 PMID:1879833 PMID:1924316 PMID:1945893 PMID:1953767 PMID:1972698 PMID:1978554 PMID:1978555 PMID:1999339 PMID:1999409 PMID:2157298 PMID:2190319 PMID:2222408 PMID:2253938 PMID:2255919 PMID:2263506 PMID:2307454 PMID:2321910 PMID:2393028 PMID:2503817 PMID:2572288 PMID:2602358 PMID:2606066 PMID:2633878 PMID:2836867 PMID:2849540 PMID:2895981 PMID:2912069 PMID:2912886 PMID:3198117 PMID:3201886 PMID:3338798 PMID:3393536 PMID:3446582 PMID:3565372 PMID:3591235 PMID:3740052 PMID:4154774 PMID:4283789 PMID:4359638 PMID:4379606 PMID:4388132 PMID:4392654 PMID:4435794 PMID:4721339 PMID:4837298 PMID:4838696 PMID:4974311 PMID:5081671 PMID:5305539 PMID:5316621 PMID:5369703 PMID:5413384 PMID:5485383 PMID:5641629 PMID:5673160 PMID:5770172 PMID:5775246 PMID:5779160 PMID:5844610 PMID:6015571 PMID:6344088 PMID:6500558 PMID:6698555 PMID:6714978 PMID:6714986 PMID:6805883 PMID:7055648 PMID:7129446 PMID:7160841 PMID:7203486 PMID:7211845 PMID:7327562 PMID:7390473 PMID:7440223 PMID:7577654 PMID:7590755 PMID:7655862 PMID:7789945 PMID:7803800 PMID:7806085 PMID:7825590 PMID:7849299 PMID:7858267 PMID:7870632 PMID:7947239 PMID:7947250 PMID:7949118 PMID:7959686 PMID:7959695 PMID:8118045 PMID:8141125 PMID:8193373 PMID:8241497 PMID:8244337 PMID:8364584 PMID:8370579 PMID:8436389 PMID:8447319 PMID:8471773 PMID:8477268 PMID:8490627 PMID:8533762 PMID:8537082 PMID:8611726 PMID:8807085 PMID:8807321 PMID:8807322 PMID:8813094 PMID:8956035 PMID:9017974 PMID:9192788 PMID:9233561 PMID:9250351 PMID:9290617 PMID:9298828 PMID:9299858 PMID:9332310 PMID:9342374 PMID:9384614 PMID:9410474 PMID:9444913 PMID:9536098 PMID:9589612 PMID:9674740 PMID:9858856 PMID:10192449 PMID:10221015 PMID:10480214 PMID:10502785 PMID:10556177 PMID:10571945 PMID:10627140 PMID:10643148 PMID:10666231 PMID:10734064 PMID:10772881 PMID:10782016 PMID:10916676 PMID:11024211 PMID:11042039 PMID:11112389 PMID:11146567 PMID:11243133 PMID:11261779 PMID:11271380 PMID:11295127 PMID:11379875 PMID:11400791 PMID:11445808 PMID:11484161 PMID:11499668 PMID:11594515 PMID:11601226 PMID:11748843 PMID:11780463 PMID:11793482 PMID:11852882 PMID:11968085 PMID:12028056 PMID:12064901 PMID:12064902 PMID:12064920 PMID:12105841 PMID:12130518 PMID:12187030 PMID:12215013 PMID:12367584 PMID:12497642 PMID:12737938 PMID:12737940 PMID:12768444 PMID:12850494 PMID:14014720 PMID:14278484 PMID:14505231 PMID:14757424 PMID:14757426 PMID:15065213 PMID:15223006 PMID:15315792 PMID:15349799 PMID:15466166 PMID:15502081 PMID:15625830 PMID:15727905 PMID:15766741 PMID:15858258 PMID:15906717 PMID:15914531 PMID:15996881 PMID:16079115 PMID:16088936 PMID:16119988 PMID:16136268 PMID:16143877 PMID:16155737 PMID:16193512 PMID:16329560 PMID:16356170 PMID:16427346 PMID:16461316 PMID:16513531 PMID:16528451 PMID:16601897 PMID:16607506 PMID:16753852 PMID:16777444 PMID:16927025 PMID:16934959 PMID:16944148 PMID:17018380 PMID:17233850 PMID:17524386 PMID:17576681 PMID:17587269 PMID:17611006 PMID:17726510 PMID:17877203 PMID:17959407 PMID:18043863 PMID:18046504 PMID:18056001 PMID:18066402 PMID:18086567 PMID:18177777 PMID:18226470 PMID:18270558 PMID:18329300 PMID:18452027 PMID:18568599 PMID:18627054 PMID:18677765 PMID:19224086 PMID:19396829 PMID:19422023 PMID:19465117 PMID:19589177 PMID:19594365 PMID:19632868 PMID:19846429 PMID:20007901 PMID:20052779 PMID:20085579 PMID:20200584 PMID:20203002 PMID:20236109 PMID:20582980 PMID:20602793 PMID:20621077 PMID:20713184 PMID:20949590 PMID:21063220 PMID:21153663 PMID:21302115 PMID:21397531 PMID:21441392 PMID:21446359 PMID:21479984 PMID:21507207 PMID:21637675 PMID:21677401 PMID:21874587 PMID:21931771 PMID:21989994 PMID:22018328 PMID:22139979 PMID:22164279 PMID:22165289 PMID:22171972 PMID:22237549 PMID:22281021 PMID:22293322 PMID:22307442 PMID:22382802 PMID:22452742 PMID:22552160 PMID:22770933 PMID:22906047 PMID:22906837 PMID:22963789 PMID:22963798 PMID:23006493 PMID:23057857 PMID:23144702 PMID:23365477 PMID:23389243 PMID:23409742 PMID:23479361 PMID:23660394 PMID:23757202 PMID:23926329 PMID:23965028 PMID:24022758 PMID:24033266 PMID:24117340 PMID:24134566 PMID:24365856 PMID:24460025 PMID:24505519 PMID:24551785 PMID:24586352 PMID:24711023 PMID:24787449 PMID:24962355 PMID:25071003 PMID:25141282 PMID:25189226 PMID:25201310 PMID:25326637 PMID:25407525 PMID:25440321 PMID:25536053 PMID:25541721 PMID:25548459 PMID:25741868 PMID:25775246 PMID:25925739 PMID:26060661 PMID:26226515 PMID:26275698 PMID:26479991 PMID:26633385 PMID:26693676 PMID:26823837 PMID:26827633 PMID:26829728 PMID:26990548 PMID:27040960 PMID:27053284 PMID:27213370 PMID:27287612 PMID:27408423 PMID:27495838 PMID:27519946 PMID:27535533 PMID:27853304 PMID:27880809 PMID:27884173 PMID:27914961 PMID:27941691 PMID:27980749 PMID:28028996 PMID:28059001 PMID:28195434 PMID:28356147 PMID:28492532 PMID:28512736 PMID:28583873 PMID:28756180 PMID:28824188 PMID:28852037 PMID:29072585 PMID:29138396 PMID:29141760 PMID:29248304 PMID:29300386 PMID:29333274 PMID:29339739 PMID:29396846 PMID:30045279 PMID:30077011 PMID:30096395 PMID:30097005 PMID:30161219 PMID:30314477 PMID:30315739 PMID:30674319 PMID:30988594 PMID:31294066 PMID:31489982 PMID:31525211 PMID:31590661 PMID:31602632 PMID:31609781 PMID:31833391 PMID:31862010 PMID:31863082 PMID:32156605 PMID:32180910 PMID:32387441 PMID:32387609 PMID:32425388 PMID:32641076 PMID:32680472 PMID:32702756 PMID:32860008 PMID:32987391 PMID:33051526 PMID:33069889 PMID:33072997 PMID:33128437 PMID:33413378 PMID:33536406 PMID:33628497 PMID:33636823 PMID:33637102 PMID:33708821 PMID:34007417 PMID:34134107 PMID:34272389 PMID:34532700 PMID:34620237 PMID:34643346 PMID:34659341 PMID:34762759 PMID:34895177 PMID:34934109 PMID:34966093 PMID:34989400 PMID:35313968 PMID:35384376 PMID:35695473 PMID:35753512 PMID:35840819 PMID:35845714 PMID:36089067 PMID:36150187 PMID:36212124 PMID:36212142 PMID:36315991 PMID:36353116 PMID:36681081 PMID:36703223 PMID:36704359 PMID:36949502 PMID:38066190 PMID:38645242 PMID:38970298 More...
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gdi1
GDP dissociation inhibitor 1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,087,611...152,094,274
Ensembl chr X:152,087,444...152,094,272
G
H2ab3
H2A.B variant histone 3
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:82,362,531...82,363,105
Ensembl chr X:82,362,633...82,362,983
G
Haus7
HAUS augmin-like complex, subunit 7
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:151,154,979...151,174,441
Ensembl chr X:151,154,979...151,180,577
G
Hcfc1
host cell factor C1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,687,779...151,712,688
Ensembl chr X:151,687,779...151,712,638
G
Idh3g
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,515,244...151,524,175
Ensembl chr X:151,515,247...151,524,171
G
Ikbkg
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency | ClinVar Annotator: match by term: G6PD A-
ClinVar
PMID:1945893 PMID:3198117 PMID:6805883 PMID:7803800 PMID:8244337 PMID:8471773 PMID:9384614 PMID:9589612 PMID:10480214 PMID:10502785 PMID:10627140 PMID:11379875 PMID:11601226 PMID:11748843 PMID:11968085 PMID:12064920 PMID:15727905 PMID:16329560 PMID:16427346 PMID:16601897 PMID:16607506 PMID:18046504 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19589177 PMID:19846429 PMID:21446359 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:25741868 PMID:28492532 PMID:29300386 PMID:29339739 PMID:30045279 PMID:30315739 PMID:31489982 PMID:31862010 PMID:31863082 PMID:33051526 PMID:33072997 PMID:34620237 PMID:34659341 PMID:34762759 PMID:34895177 PMID:34989400 PMID:35313968 PMID:35384376 PMID:35840819 PMID:36212142 PMID:36353116 More...
NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
G
Irak1
interleukin-1 receptor-associated kinase 1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
G
L1cam
L1 cell adhesion molecule
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,597,270...151,623,776
Ensembl chr X:151,597,277...151,623,857
G
Lage3
L antigen family, member 3
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,138,209...152,139,632
Ensembl chr X:152,138,218...152,139,632
G
Mecp2
methyl CpG binding protein 2
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,781,177...151,844,687
Ensembl chr X:151,789,930...151,844,689
G
Mpp1
MAGUK p55 scaffold protein 1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
G
Mtcp1
mature T-cell proliferation 1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr18:126,189...130,123
G
Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,656,056...151,661,304
Ensembl chr X:151,656,056...151,661,252
G
Nsdhl
NAD(P) dependent steroid dehydrogenase-like
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
G
Opn1mw
opsin 1, medium wave sensitive
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,905,056...151,925,419
Ensembl chr X:151,905,096...151,925,388
G
Pdzd4
PDZ domain containing 4
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,530,390...151,560,779
Ensembl chr X:151,530,390...151,560,826
G
Plxna3
plexin A3
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,115,699...152,131,608
Ensembl chr X:152,115,819...152,131,603
G
Plxnb3
plexin B3
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,493,832...151,508,688
Ensembl chr X:151,494,207...151,508,674
G
Pnck
pregnancy up-regulated nonubiquitous CaM kinase
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:151,369,406...151,373,508
Ensembl chr X:151,369,410...151,373,446
G
Pnma3
PNMA family member 3
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:150,906,080...150,912,674
Ensembl chr X:150,906,278...150,910,839
G
Pnma5
PNMA family member 5
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:150,880,865...150,882,789
Ensembl chr X:150,880,865...150,882,789
G
Pnma6e
PNMA family member 6E
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:151,103,531...151,108,630
Ensembl chr X:151,103,755...151,106,037
G
Renbp
renin binding protein
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,661,463...151,670,538
Ensembl chr X:151,661,458...151,670,516
G
Rpl10
ribosomal protein L10
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,054,562...152,056,769
Ensembl chr X:152,054,452...152,056,761
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Slc10a3
solute carrier family 10, member 3
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,154,757...152,158,563
Ensembl chr X:152,151,076...152,162,958
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Slc6a8
solute carrier family 6 member 8
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,384,675...151,393,979
Ensembl chr X:151,384,675...151,393,979
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Srpk3
SRSF protein kinase 3
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,510,452...151,515,208
Ensembl chr X:151,510,539...151,515,198
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Ssr4
signal sequence receptor subunit 4
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,524,191...151,528,218
Ensembl chr X:151,524,009...151,528,202
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Tafazzin
tafazzin, phospholipid-lysophospholipid transacylase
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:25741868 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,065,539...152,076,178
Ensembl chr X:152,065,609...152,074,001
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Tex28
testis expressed 28
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,922,210...151,955,902
Ensembl chr X:151,925,526...151,954,567
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Tktl1
transketolase-like 1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:151,954,261...151,987,208
Ensembl chr X:151,954,175...151,987,208
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Trex2
three prime repair exonuclease 2
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:151,151,862...151,153,470
Ensembl chr X:151,151,864...151,153,479
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Ubl4a
ubiquitin-like 4A
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:9384614 PMID:10480214 PMID:11379875 PMID:11748843 PMID:11968085 PMID:16427346 PMID:16601897 PMID:18177777 PMID:18627054 PMID:19396829 PMID:19846429 PMID:22281021 PMID:22382802 PMID:23409742 PMID:23660394 PMID:24365856 PMID:24962355 PMID:28492532 PMID:35384376 More...
NCBI chr X:152,151,242...152,154,094
Ensembl chr X:152,151,460...152,154,069
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Vbp1
VHL binding protein 1
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
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Zfp185
zinc finger protein 185
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:150,831,869...150,877,652
Ensembl chr X:150,831,862...150,874,810
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Zfp92
ZFP92 zinc finger protein
ISO
ClinVar Annotator: match by term: Anemia, nonspherocytic hemolytic, due to G6PD deficiency
ClinVar
PMID:18177777 PMID:28492532
NCBI chr X:151,116,794...151,142,451
Ensembl chr X:151,117,102...151,143,177
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Ank3
ankyrin 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29109170
NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
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Apoe
apolipoprotein E
ISO
RGD
PMID:15007105
RGD:12904641
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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Bpifa1
BPI fold containing family A, member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15513904
NCBI chr 3:142,627,810...142,633,553
Ensembl chr 3:142,627,810...142,633,552
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Cat
catalase
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:26074427
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Crhr1
corticotropin releasing hormone receptor 1
sexual_dimorphism
IEP
associated with chronic mild stress, age effect; mRNA:altered expression:hippocampus (rat)
RGD
PMID:29251811
RGD:401965484
NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
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Dio3
iodothyronine deiodinase 3
treatment
IEP
RGD
PMID:23763370
RGD:13432044
NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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Dnmt1
DNA methyltransferase 1
IEP
mRNA,protein:increased expression:Pituitary gland (rat)
RGD
PMID:26509893
RGD:11344152
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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Dnmt3b
DNA methyltransferase 3 beta
IEP
mRNA:increased expression:pituitary gland (rat)
RGD
PMID:26509893
RGD:11344152
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
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Drd2
dopamine receptor D2
IDA IEP
DNA:Hypermethylation:promoter mRNA:decreased expression: pituitary gland (rat)
RGD
PMID:26509893 PMID:28710248
RGD:11344152 , RGD:401960105
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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Ehmt2
euchromatic histone lysine methyltransferase 2
IEP
mRNA:increased expression:pituitary gland (rat)
RGD
PMID:26509893
RGD:11344152
NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
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Gabrb3
gamma-aminobutyric acid type A receptor subunit beta 3
treatment sexual_dimorphism
IEP ISO
in male mice only; mRNA:increased expression:frontal cortex:
RGD
PMID:23763370 PMID:30312858
RGD:13432044 , RGD:405866345
NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
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Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
IEP
mRNA:increased expression:posterior hypothalamic region (rat)
RGD
PMID:18514412
RGD:402528884
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
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Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
treatment
IMP IEP
RGD
PMID:22037411 PMID:23763370
RGD:13210751 , RGD:13432044
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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Hdac2
histone deacetylase 2
IEP
mRNA,protein:increased expression:pituitary gland (rat)
RGD
PMID:26509893
RGD:11344152
NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
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Hdac4
histone deacetylase 4
IEP
mRNA,protein:increased expression:pituitary gland (rat)
RGD
PMID:26509893
RGD:11344152
NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
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Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
IEP
protein:increased expression:placenta (rat)
RGD
PMID:26342748
RGD:401965481
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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Igf1
insulin-like growth factor 1
IEP
mRNA:decreased expression:cerebellum (rat)
RGD
PMID:16909201
RGD:12904886
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igf1r
insulin-like growth factor 1 receptor
IEP
protein:decreased activity:cerebellum (rat)
RGD
PMID:16909201
RGD:12904886
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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Mat2a
methionine adenosyltransferase 2A
IEP
mRNA:decreased expression:brain (rat)
RGD
PMID:26180184
RGD:11074449
NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
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Mecp2
methyl CpG binding protein 2
treatment
IEP
mRNA:increased expression:pituitary gland (rat)
RGD
PMID:26509893 PMID:23763370
RGD:11344152 , RGD:13432044
NCBI chr X:151,781,177...151,844,687
Ensembl chr X:151,789,930...151,844,689
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Mir326
microRNA 326
IEP
miRNA:increases expression:pituitary gland (rat)
RGD
PMID:28710248
RGD:401960105
NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123
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Mir9
microRNA 9
IEP
miRNA:increased expression:pituitary gland (rat)
RGD
PMID:28710248
RGD:401960105
NCBI chr 9:1,080,274...1,080,383
Ensembl chr 9:1,080,274...1,080,383
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Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
IEP
mRNA:decreased expression:brain (rat)
RGD
PMID:26180184
RGD:11074449
NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
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Nos1
nitric oxide synthase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25511929
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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Nr3c2
nuclear receptor subfamily 3, group C, member 2
sexual_dimorphism
IEP
associated with chronic mild stress, age effect; mRNA:altered expression:hippocampus (rat)
RGD
PMID:29251811
RGD:401965484
NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
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Oprk1
opioid receptor, kappa 1
IEP
DNA, mRNA:hypomethylation, increased expression:ventral tegmental area, prefrontal cortex
RGD
PMID:29678771
RGD:401851055
NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
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Oprl1
opioid related nociceptin receptor 1
IEP
mRNA:decreased expression:ventral tegmental area
RGD
PMID:29678771
RGD:401851055
NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
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Pdyn
prodynorphin
IEP
DNA, mRNA:hypomethylation, altered expression:ventral tegmental area, nucleus accumbens
RGD
PMID:29678771
RGD:401851055
NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
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Per2
period circadian regulator 2
treatment
ISO
RGD
PMID:31329297
RGD:405878078
NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
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Pnoc
prepronociceptin
IEP
mRNA:increased expression:nucleus accumbens
RGD
PMID:29678771
RGD:401851055
NCBI chr15:39,624,635...39,652,463
Ensembl chr15:39,624,641...39,651,867
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Pomc
proopiomelanocortin
treatment
ISO
RGD
PMID:31329297
RGD:405878078
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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Prl
prolactin
IEP
mRNA,protein:increased expression:pituitary gland, blood plasma (rat) mRNA, protein:increased expression:pituitary gland, blood plasma (rat)
RGD
PMID:26509893 PMID:28710248
RGD:11344152 , RGD:401960105
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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Pten
phosphatase and tensin homolog
IEP
Protein:increased expression, increased activity:cerebellum (rat)
RGD
PMID:12700235
RGD:12801493
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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Rasgrf1
RAS protein-specific guanine nucleotide-releasing factor 1
treatment
IEP
RGD
PMID:23763370
RGD:13432044
NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269
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Rps6ka1
ribosomal protein S6 kinase A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29109170
NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272
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Setd7
SET domain containing 7, histone lysine methyltransferase
IEP
mRNA:decreased expression:pituitary gland (rat)
RGD
PMID:26509893
RGD:11344152
NCBI chr 2:135,562,683...135,605,468
Ensembl chr 2:135,562,683...135,605,468
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Slc25a12
solute carrier family 25 member 12
treatment
IEP
RGD
PMID:23763370
RGD:13432044
NCBI chr 3:56,097,166...56,191,841
Ensembl chr 3:56,097,269...56,192,100
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Slc6a4
solute carrier family 6 member 4
IEP
mRNA:decreased expression:brain (rat)
RGD
PMID:26180184
RGD:11074449
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
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Tlr4
toll-like receptor 4
ameliorates
ISO
RGD
PMID:30312858
RGD:405866345
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Ube3a
ubiquitin protein ligase E3A
treatment
IEP
RGD
PMID:23763370
RGD:13432044
NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250
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Rhoa
ras homolog family member A
IEP
protein:increased activation:neuron, cerebellum
RGD
PMID:17109064
RGD:2298867
NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
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Atp5f1e
ATP synthase F1 subunit epsilon
IEP
mRNA:decreased expression:heart, mitochondrion (rat)
RGD
PMID:21251948
RGD:5131501
NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
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Atp5po
ATP synthase peripheral stalk subunit OSCP
IEP
mRNA:decreased expression:heart, mitochondrion (rat)
RGD
PMID:21251948
RGD:5131501
NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30259626
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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Gli1
GLI family zinc finger 1
IEP
RGD
PMID:25623978
RGD:12879410
NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
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Shh
sonic hedgehog signaling molecule
IEP
RGD
PMID:25623978
RGD:12879410
NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
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Smo
smoothened, frizzled class receptor
treatment
IMP
RGD
PMID:24388991
RGD:12879411
NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
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Hp
haptoglobin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21075095
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
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Gpt
glutamic--pyruvic transaminase
treatment
IEP
RGD
PMID:28921207
RGD:14975164
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Il16
interleukin 16
IEP
protein:increased expression:brain
RGD
PMID:14698845
RGD:1354526
NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
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Daxx
death-domain associated protein
IEP
mRNA:increased expression:liver:
RGD
PMID:17692352
RGD:9587799
NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
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Kdm3b
lysine demethylase 3B
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21262293
NCBI chr18:26,380,859...26,436,701
Ensembl chr18:26,380,964...26,436,628
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Kdr
kinase insert domain receptor
IEP
RGD
PMID:20058324
RGD:5684396
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
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Alad
aminolevulinate dehydratase
IDA IEP ISO
protein:decreased activity:blood (rat) CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:21396434 PMID:23792432 PMID:24631795 PMID:16597373 PMID:19647414
RGD:1599014 , RGD:4144142
NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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Glul
glutamate-ammonia ligase
IEP
protein:increased expression:stellate ganglion
RGD
PMID:29457680
RGD:401794593
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
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Hfe
homeostatic iron regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20659343
NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
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Mmp9
matrix metallopeptidase 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16700817
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mt4
metallothionein 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19921116
NCBI chr19:10,863,813...10,865,909
Ensembl chr19:10,863,813...10,865,909
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Nqo1
NAD(P)H quinone dehydrogenase 1
treatment
IEP
RGD
PMID:28178683
RGD:13440092
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Qdpr
quinoid dihydropteridine reductase
IEP
protein:increased activity:brain, caudate nucleus (rat)
RGD
PMID:2359144
RGD:5128598
NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854
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Ryr1
ryanodine receptor 1
ISO
mRNA:decreased expression:peripheral blood mononuclear cell
RGD
PMID:30661027
RGD:329812013
NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812
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Vdr
vitamin D receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20692022 PMID:23433214
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
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Xpo5
exportin 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28042866
NCBI chr 9:14,740,182...14,778,171
Ensembl chr 9:14,740,182...14,778,171
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Xrcc3
X-ray repair cross complementing 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23803535
NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
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Alad
aminolevulinate dehydratase
IEP
protein:decreased activity:striatum (rat)
RGD
PMID:18778733
RGD:4144152
NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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Atp13a2
ATPase cation transporting 13A2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22285144
NCBI chr 5:153,292,722...153,312,143
Ensembl chr 5:153,292,751...153,312,139
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Bnip3
BCL2 interacting protein 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19442826
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12171760
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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Htt
huntingtin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:19845833
NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
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Ifng
interferon gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18041089
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Il1b
interleukin 1 beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18041089
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Mfn2
mitofusin 2
IEP
protein:decreased expression:striatum (rat)
RGD
PMID:28232070
RGD:12910738
NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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Nos2
nitric oxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15010209 PMID:22174044
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Prkn
parkin RBR E3 ubiquitin protein ligase
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:20089134
NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
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Slc30a10
solute carrier family 30, member 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28860195 PMID:29429640
NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103
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Slc31a1
solute carrier family 31 member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22465424
NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
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Slc39a14
solute carrier family 39 member 14
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28860195
NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524
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Slc39a8
solute carrier family 39 member 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29429640
NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
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Snca
synuclein alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23934647
NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18041089
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Apoe
apolipoprotein E
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16891999
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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Gpx1
glutathione peroxidase 1
ISO
RGD
PMID:18758054
RGD:7240571
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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Gpx3
glutathione peroxidase 3
IDA
protein:decreased activity:plasma
RGD
PMID:25975991
RGD:401827854
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
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Icam1
intercellular adhesion molecule 1
IEP
protein:increased secretion:serum (rat)
RGD
PMID:20508868
RGD:4145621
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Nqo1
NAD(P)H quinone dehydrogenase 1
treatment
IEP
RGD
PMID:28498799
RGD:13439738
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Ctsb
cathepsin B
IMP
RGD
PMID:18638529
RGD:2315510
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15515958
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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S100b
S100 calcium binding protein B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30076900
NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
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Aqp9
aquaporin 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29566083
NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
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Il17a
interleukin 17A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:31351185
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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Ins2
insulin 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:26364587
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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Alad
aminolevulinate dehydratase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21439310
NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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Ep300
E1A binding protein p300
IEP
mRNA:increased expression:hippocampus
RGD
PMID:24291742
RGD:9588309
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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Slc6a1
solute carrier family 6 member 1
IEP
protein:increased expression:brain, synaptosome
RGD
PMID:15149801
RGD:1643208
NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293
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Ache
acetylcholinesterase
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:3669600 PMID:8359835 PMID:23000449
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
G
Bche
butyrylcholinesterase
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:22981459 PMID:22982776 PMID:23044488 PMID:23123253 PMID:23178380 PMID:23220586 PMID:26239905 PMID:31201777 More...
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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Gsr
glutathione-disulfide reductase
treatment
IEP
RGD
PMID:24188896
RGD:10401876
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Pepd
peptidase D
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:22982776
NCBI chr 1:87,536,650...87,681,233
Ensembl chr 1:87,536,609...87,681,231
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Pon1
paraoxonase 1
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:11022865 PMID:20581384 PMID:20981111 PMID:23123254 PMID:24326413 PMID:26340881 PMID:28070599 More...
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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Agtr1a
angiotensin II receptor, type 1a
IEP
RGD
PMID:24814703
RGD:10047100
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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Agtr1b
angiotensin II receptor, type 1b
IEP
RGD
PMID:24814703
RGD:10047100
NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232
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Bdnf
brain-derived neurotrophic factor
treatment
IEP ISO
associated with brain ischemia
RGD
PMID:29571823 PMID:33324197 PMID:29599834 PMID:34964700
RGD:401959211 , RGD:405850212 , RGD:401976548 , RGD:401965400
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Creb1
cAMP responsive element binding protein 1
treatment
IDA ISO
protein:decreased phosphorylation:hippocampus
RGD
PMID:29571823 PMID:37736695 PMID:36688960
RGD:401959211 , RGD:401960090 , RGD:401959611
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Gdnf
glial cell derived neurotrophic factor
treatment
IEP ISO IDA
protein:decreased expression:hippocampus,urine protein:altered expression:hippocampus, urine associated with rheumatic heart disease;protein:increased expression:serum
RGD
PMID:36688960 PMID:34728231 PMID:29512789 PMID:28918204 PMID:33324197 PMID:25251457 More...
RGD:401959611 , RGD:405866364 , RGD:405850251 , RGD:405850250 , RGD:405850212 , RGD:405849389
NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
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Igfbp7
insulin-like growth factor binding protein 7
ISO
protein:increased expression:plasma (human)
RGD
PMID:25543030
RGD:401960875
NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
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Il1b
interleukin 1 beta
treatment
IDA IEP
protein:increased expression:hippocampus (rat)
RGD
PMID:22959208 PMID:33390808 PMID:29571823
RGD:7204702 , RGD:401965467 , RGD:401959211
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il1rn
interleukin 1 receptor antagonist
treatment
ISO
human protein in a rat model
RGD
PMID:23077050
RGD:8551854
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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Il6
interleukin 6
IEP
protein:increased expression:hippocampus (rat)
RGD
PMID:33390808
RGD:401965467
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ireb2
iron responsive element binding protein 2
IEP
protein:increased expression:hippocampus (rat)
RGD
PMID:23229539
RGD:12904023
NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
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Mapk1
mitogen activated protein kinase 1
treatment
IDA ISO
protein:decreased phosphorylation:hippocampus
RGD
PMID:36688960 PMID:37736695
RGD:401959611 , RGD:401960090
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
treatment
IDA ISO
protein:decreased phosphorylation:hippocampus
RGD
PMID:36688960 PMID:37736695
RGD:401959611 , RGD:401960090
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Ngf
nerve growth factor
treatment
ISO IEP
associated with brain ischemia
RGD
PMID:30481505 PMID:29599834 PMID:34964700 PMID:30481505
RGD:401965395 , RGD:401976548 , RGD:401965400 , RGD:401965395
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
treatment
IDA
RGD
PMID:28086911
RGD:408345237
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Nr3c2
nuclear receptor subfamily 3, group C, member 2
IEP IMP
protein:increased expression:hippocampus (rat)
RGD
PMID:33390808 PMID:33390808
RGD:401965467 , RGD:401965467
NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
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Tnf
tumor necrosis factor
treatment
IEP
protein:increased expression:hippocampus (rat)
RGD
PMID:29571823 PMID:33390808
RGD:401959211 , RGD:401965467
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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F3
coagulation factor III, tissue factor
IEP
protein:increased expression:lung, skin, plasma
RGD
PMID:24831016
RGD:11341687
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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Ache
acetylcholinesterase
disease_progression
ISO
RGD
PMID:8043620
RGD:405855847
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Htr1a
5-hydroxytryptamine receptor 1A
IEP
mRNA, protein:increased expression:hippocampal formation, amygdala
RGD
PMID:27760517
RGD:405850209
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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Ace
angiotensin I converting enzyme
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17196621
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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Adora2a
adenosine A2a receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20799992
NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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Akt1
AKT serine/threonine kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21041608
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Camk2b
calcium/calmodulin-dependent protein kinase II beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17603807
NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
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Esr1
estrogen receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19386276
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Grm2
glutamate metabotropic receptor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20211215
NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
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Gstp1
glutathione S-transferase pi 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15729709
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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Htr1a
5-hydroxytryptamine receptor 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19747927
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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Htr6
5-hydroxytryptamine receptor 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20705401
NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912
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Npy1r
neuropeptide Y receptor Y1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19566775
NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
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Oprm1
opioid receptor, mu 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16402083
NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
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Phb1
prohibitin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18504422
NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
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Pick1
protein interacting with PRKCA 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17606663
NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
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Rgs9
regulator of G-protein signaling 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17318883
NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892
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Slc6a3
solute carrier family 6 member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12931138
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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Snca
synuclein alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15542733
NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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Sod2
superoxide dismutase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16807759
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
treatment
ISO
associated with schizophrenia
RGD
PMID:10889552
RGD:1358545
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Drd3
dopamine receptor D3
ISO
associated with schizophrenia
RGD
PMID:12960753
RGD:1581250
NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
G
Sod2
superoxide dismutase 2
ISO
associated with schizophrenia
RGD
PMID:12960753
RGD:1581250
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Abcb1a
ATP binding cassette subfamily B member 1A
susceptibility
ISO
associated with Precursor Cell Lymphoblastic Leukemia-Lymphoma;DNA:SNP: 3435T>C(human) CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12352921 PMID:17938643
RGD:11081146
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcg2
ATP binding cassette subfamily G member 2
susceptibility
ISO
associated with Precursor Cell Lymphoblastic Leukemia-Lymphoma;DNA:SNP: :421C>A(human)
RGD
PMID:17938643
RGD:11081146
NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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Adcyap1
adenylate cyclase activating polypeptide 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:29604313
NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
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Add3
adducin 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
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Adra1b
adrenoceptor alpha 1B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19125850
NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
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Alox5ap
arachidonate 5-lipoxygenase activating protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
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Bche
butyrylcholinesterase
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21620937
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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Bcl2l1
Bcl2-like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Casp3
caspase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21972528
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cat
catalase
IEP
protein:decreased activity:serum:
RGD
PMID:16938375
RGD:9068882
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cck
cholecystokinin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
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Cd3d
CD3 delta subunit of T-cell receptor complex
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809
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Crispld2
cysteine-rich secretory protein LCCL domain containing 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465
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Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21225912
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
G
Drd2
dopamine receptor D2
IEP
mRNA:decreased expression:hippocampus (rat)
RGD
PMID:19576243
RGD:2311553
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
G
Egln1
egl-9 family hypoxia-inducible factor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29471019
NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
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Epha4
Eph receptor A4
IEP
RGD
PMID:10336070
RGD:5688752
NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
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Ephx1
epoxide hydrolase 1
susceptibility
ISO
DNA:missense mutation:cds:p.H139R (human)
RGD
PMID:17022435
RGD:5490249
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:19220411
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Gabrr2
gamma-aminobutyric acid type A receptor subunit rho 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr 5:47,445,280...47,489,929
Ensembl chr 5:47,452,150...47,489,809
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Gstm1
glutathione S-transferase mu 1
susceptibility
ISO
DNA:deletion: :
RGD
PMID:8923609 PMID:27220440
RGD:5490214 , RGD:14700956
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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Gstp1
glutathione S-transferase pi 1
susceptibility
ISO
DNA:polymorphism: :
RGD
PMID:17022435
RGD:5490249
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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Igf1r
insulin-like growth factor 1 receptor
ISO
DNA: snp: intron: rs1879612: bortezomib induced
RGD
PMID:20864405
RGD:5686413
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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Il10
interleukin 10
treatment
IDA
RGD
PMID:23916895
RGD:7364985
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Lat
linker for activation of T cells
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578
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Mtor
mechanistic target of rapamycin kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16955484
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Nfe2l2
NFE2 like bZIP transcription factor 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:20211941
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nlrp3
NLR family, pyrin domain containing 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32014472
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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Nqo1
NAD(P)H quinone dehydrogenase 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:20849151
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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P2rx1
purinergic receptor P2X 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623
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Plat
plasminogen activator, tissue type
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19442825
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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Pon1
paraoxonase 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21329748
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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Prkcd
protein kinase C, delta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22512859
NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
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Ptges3
prostaglandin E synthase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29471019
NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
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Rnase6
ribonuclease A family member 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr15:24,354,305...24,357,289
Ensembl chr15:24,354,303...24,357,328
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Slc18a2
solute carrier family 18 member A2
IEP
protein:increased expression:thalamus (rat)
RGD
PMID:19798748
RGD:5130970
NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
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Srsf5
serine and arginine rich splicing factor 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
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St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708
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Tgm1
transglutaminase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
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Timp3
TIMP metallopeptidase inhibitor 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19784758
NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
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Oxt
oxytocin/neurophysin I prepropeptide
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:292422 PMID:803783 PMID:3923190 PMID:4988877 PMID:5067144 PMID:5493616 PMID:5528113 PMID:7360068 More...
NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
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Uts2
urotensin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16160878
NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237
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Pomc
proopiomelanocortin
ISO
protein:increased expression:mammillary body
RGD
PMID:1650797
RGD:407572523
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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