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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
Akathisia, Drug-Induced 
Alcohol-Induced Disorders, Nervous System +   
botulism +  
Charcot-Marie-Tooth Disease with Ptosis and Parkinsonism 
Drug-Induced Dyskinesia +   
Heavy Metal Poisoning, Nervous System +   
MPTP Poisoning  
A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)
neuroleptic malignant syndrome 
postencephalitic Parkinson disease 

Synonyms
Exact Synonyms: MPTP Induced Degeneration of the Striatum ;   MPTP Induced Parkinsonism ;   MPTP Neurotoxicity Syndrome ;   MPTP Neurotoxicity Syndromes ;   Poisoning, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Primary IDs: MESH:D020267 ;   RDO:0007382
Definition Sources: MESH:D020267

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