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GENE - TERM ANNOTATION REPORT

6 Annotations Found.

An association has been curated linking Nr1h4 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Tian J, etal., Sci Rep. 2017 Aug 21;7(1):8938. doi: 10.1038/s41598-017-09131-2.
  • 13 additional annotations were made from Tian J, etal., Sci Rep. 2017 Aug 21;7(1):8938. doi: 10.1038/s41598-017-09131-2.
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 70 papers in RGD have been used to annotate Nr1h4
  • Curation Notes: mRNA:decreased expression:liver (rat)


    • An association has been curated linking Nr1h4 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with NR1H4 (Homo sapiens) [(EXP) inferred from experiment]
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 70 papers in RGD have been used to annotate Nr1h4
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:12875239


    • An association has been curated linking Nr1h4 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Zhang L, etal., Hepatology. 2012 Dec;56(6):2336-43. doi: 10.1002/hep.25905.
  • The annotation has been inferred from sequence orthology with Nr1h4 (Mus musculus) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Zhang L, etal., Hepatology. 2012 Dec;56(6):2336-43. doi: 10.1002/hep.25905.
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 70 papers in RGD have been used to annotate Nr1h4
  • Qualifier: severity


    • An association has been curated linking Nr1h4 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Lee FY, etal., Mol Endocrinol. 2010 Aug;24(8):1626-36. doi: 10.1210/me.2010-0117. Epub 2010 Jun 23.
  • The annotation has been inferred from sequence orthology with Nr1h4 (Mus musculus) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Lee FY, etal., Mol Endocrinol. 2010 Aug;24(8):1626-36. doi: 10.1210/me.2010-0117. Epub 2010 Jun 23.
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 70 papers in RGD have been used to annotate Nr1h4
  • Qualifier: treatment


    • An association has been curated linking Nr1h4 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Qu X, etal., Biol Pharm Bull. 2018;41(8):1211-1218. doi: 10.1248/bpb.b18-00028.
  • 8 additional annotations were made from Qu X, etal., Biol Pharm Bull. 2018;41(8):1211-1218. doi: 10.1248/bpb.b18-00028.
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 70 papers in RGD have been used to annotate Nr1h4
  • Qualifier: severity
  • Curation Notes: protein:decreased expression:liver (rat)


    • An association has been curated linking Nr1h4 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Zheng L, etal., Biomed Pharmacother. 2018 Jan;97:481-488. doi: 10.1016/j.biopha.2017.10.153. Epub 2017 Nov 6.
  • 149 additional annotations were made from Zheng L, etal., Biomed Pharmacother. 2018 Jan;97:481-488. doi: 10.1016/j.biopha.2017.10.153. Epub 2017 Nov 6.
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 70 papers in RGD have been used to annotate Nr1h4
  • Qualifier: treatment


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