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Gene: Wasl (WASP like actin nucleation promoting factor) Rattus norvegicus
Symbol: Wasl
Name: WASP like actin nucleation promoting factor
RGD ID: 735144
Description: Exhibits cytoskeletal protein binding activity and identical protein binding activity. Involved in several processes, including plasma membrane tubulation; positive regulation of cellular component organization; and vesicle transport along actin filament. Localizes to Golgi membrane; cell leading edge; and cytoplasmic vesicle. Orthologous to human WASL (WASP like actin nucleation promoting factor); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; buspirone.
Type: protein-coding
Also known as: hypothetical protein LOC685687; IQ motif and ubiquitin domain containing; Iqub; LOC682507; MGC116166; N-WASP; neural Wiskott-Aldrich syndrome protein; similar to Neural Wiskott-Aldrich syndrome protein (N-WASP); TRS4; Wiskott-Aldrich syndrome-like; Wiskott-Aldrich syndrome-like (human)
Homo sapiens (human) : WASL (WASP like actin nucleation promoting factor)  HGNC  Alliance
Mus musculus (house mouse) : Wasl (WASP like actin nucleation promoting factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wasl (WASP like actin nucleation promoting factor)
Pan paniscus (bonobo/pygmy chimpanzee) : WASL (WASP like actin nucleation promoting factor)
Canis lupus familiaris (dog) : WASL (WASP like actin nucleation promoting factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wasl (WASP like actin nucleation promoting factor)
Sus scrofa (pig) : WASL (WASP like actin nucleation promoting factor)
Chlorocebus sabaeus (African green monkey) : WASL (WASP like actin nucleation promoting factor)
Heterocephalus glaber (naked mole-rat) : Wasl (WASP like actin nucleation promoting factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0451,677,722 - 51,726,212 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl451,677,722 - 51,726,212 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0451,455,978 - 51,504,496 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4451,063,710 - 51,092,848 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1451,294,288 - 51,323,128 (-)NCBI
Celera448,249,249 - 48,297,692 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Wasl
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735144
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.