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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Imported Annotations - CTD | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Chemical and Drug Induced Liver Injury | ISO | RGD:1347655 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:25226513 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene-Chemical Interaction AnnotationsGene Ontology AnnotationsMolecular Pathway AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway AnnotationsReferences - curated| 1. | Anfinogenova Y, etal., Circ Res. 2007 Aug 17;101(4):420-8. Epub 2007 Jul 5. |
| 2. | Bu W, etal., PLoS One. 2010 Aug 13;5(8):e12153. doi: 10.1371/journal.pone.0012153. |
| 3. | Campellone KG, etal., Dev Cell. 2004 Aug;7(2):217-28. doi: 10.1016/j.devcel.2004.07.004. |
| 4. | Campellone KG, etal., PLoS Pathog. 2008 Oct;4(10):e1000191. doi: 10.1371/journal.ppat.1000191. Epub 2008 Oct 31. |
| 5. | Cantarelli VV, etal., Cell Microbiol. 2007 Jul;9(7):1782-95. doi: 10.1111/j.1462-5822.2007.00913.x. Epub 2007 Apr 19. |
| 6. | Chen JL, etal., FEBS Lett. 2004 May 21;566(1-3):281-6. |
| 7. | Fukuoka M, etal., Gene 1997 Sep 1;196(1-2):43-8. |
| 8. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 9. | GOA data from the GO Consortium |
| 10. | Icking A, etal., J Cell Sci. 2005 Nov 1;118(Pt 21):5059-69. Epub 2005 Oct 18. |
| 11. | Kessels MM and Qualmann B, EMBO J 2002 Nov 15;21(22):6083-94. |
| 12. | Lee S, etal., EMBO J. 2006 Oct 18;25(20):4983-95. Epub 2006 Sep 21. |
| 13. | Lie PP, etal., Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12562-7. doi: 10.1073/pnas.1202316109. Epub 2012 Jul 12. |
| 14. | Martinez-Quiles N, etal., Mol Cell Biol. 2004 Jun;24(12):5269-80. doi: 10.1128/MCB.24.12.5269-5280.2004. |
| 15. | MGD data from the GO Consortium |
| 16. | Miki H, etal., Nature. 1998 Jan 1;391(6662):93-6. |
| 17. | Park J, etal., J Cell Sci. 2010 May 15;123(Pt 10):1742-50. doi: 10.1242/jcs.064170. Epub 2010 Apr 27. |
| 18. | Pipeline to import KEGG annotations from KEGG into RGD |
| 19. | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 20. | Prehoda KE, etal., Science. 2000 Oct 27;290(5492):801-6. |
| 21. | RGD automated data pipeline |
| 22. | RGD automated import pipeline for gene-chemical interactions |
| 23. | Sallee NA, etal., Nature. 2008 Aug 21;454(7207):1005-8. doi: 10.1038/nature07170. Epub 2008 Jul 23. |
| 24. | Suetsugu S, etal., EMBO J. 1998 Nov 16;17(22):6516-26. |
| 25. | To C, etal., J Biol Chem. 2010 Sep 3;285(36):27944-57. doi: 10.1074/jbc.M110.103036. Epub 2010 Jun 21. |
| 26. | Volkman BF, etal., Cell 2002 Nov 15;111(4):565-76. |
| 27. | Wegner AM, etal., J Biol Chem. 2008 Jun 6;283(23):15912-20. Epub 2008 Apr 21. |
References - uncurated| PubMed | 9950691 10704453 11559594 11584276 12477932 14732713 15148305 15489334 15664188 15791211 15797550 16767080 16885158 17049400 17092940 17229736 17350575 17405146 17635999 17681954 18362183 18388313 19056867 19373774 19379711 19509061 19759398 21464958 21874009 22250195 22389406 22585739 22966049 23376485 23750457 23843614 25321392 25851601 26554011 |
Comparative Map Data| Wasl (Rattus norvegicus - Norway rat) |
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| WASL (Homo sapiens - human) |
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| Wasl (Mus musculus - house mouse) |
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| Wasl (Chinchilla lanigera - long-tailed chinchilla) |
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| WASL (Pan paniscus - bonobo/pygmy chimpanzee) |
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| WASL (Canis lupus familiaris - dog) |
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| Wasl (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| WASL (Sus scrofa - pig) |
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| WASL (Chlorocebus sabaeus - African green monkey) |
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| Wasl (Heterocephalus glaber - naked mole-rat) |
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Position Markers| RH128038 |
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| AI231276 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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RNA-SEQ Expression| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 3 | 37 | 57 | 41 | 19 | 41 | 2 | 2 | 74 | 35 | 40 | 11 | 2 |
| Low | 6 | 6 | 9 | 1 | 6 | ||||||||
| Below cutoff |
Nucleotide Sequences| RefSeq Transcripts | NM_001110365 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR07060055 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01029096 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473959 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ215931 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | ENSRNOT00000009261 ⟹ ENSRNOP00000009261 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_001110365 ⟹ NP_001103835 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
CCGCGTCCCGTGGTCTCGCCCGCCCCTGCTGCCATGTTGGATTGTGCGGCTACTGCCGCCGCCGhide sequence |
Protein Sequences| Protein RefSeqs | NP_001103835 | (Get FASTA) | NCBI Sequence Viewer |
| GenBank Protein | EDM15175 | (Get FASTA) | NCBI Sequence Viewer |
| EDM15176 | (Get FASTA) | NCBI Sequence Viewer | |
| O08816 | (Get FASTA) | NCBI Sequence Viewer |
| RefSeq Acc Id: | NP_001103835 ⟸ NM_001110365 |
| - UniProtKB: | F1LSG0 (UniProtKB/TrEMBL) |
| - Sequence: |
MSSGQQPPRRVTNVGSLLLTPQENESLFSFLGKKCVTMSSAVVQLYAADRNCMWSKKCSGVACLhide sequence |
| RefSeq Acc Id: | ENSRNOP00000009261 ⟸ ENSRNOT00000009261 |
TranscriptomePromoters| RGD ID: | 13692906 | ||||||||
| Promoter ID: | EPDNEW_R3431 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Wasl_1 | ||||||||
| Description: | Wiskott-Aldrich syndrome-like | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Sequence Variants (Rnor 6.0)
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External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:735144 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000006975 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000009261 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000009261 | ENTREZGENE, UniProtKB/TrEMBL |
| Gene3D-CATH | 2.30.29.30 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| 3.90.810.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| IMAGE_CLONE | IMAGE:7454794 | IMAGE-MGC_LOAD |
| InterPro | CRIB_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| CRIB_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| N-WASP | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| PH-like_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| WASP_C | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| WASPfam_EVH1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| WH1/EVH1_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| WH2_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| KEGG Report | rno:682507 | UniProtKB/TrEMBL |
| MGC_CLONE | MGC:116166 | IMAGE-MGC_LOAD |
| NCBI Gene | 682507 | ENTREZGENE |
| PANTHER | PTHR23202:SF39 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| Pfam | PBD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| WH1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| WH2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| PhenoGen | Wasl | PhenoGen |
| PROSITE | CRIB | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| WH1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| WH2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| SMART | PBD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| WH1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| WH2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Superfamily-SCOP | SSF47912 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| UniGene | Rn.126640 | ENTREZGENE |
| UniProt | F1LSG0 | ENTREZGENE, UniProtKB/TrEMBL |
| O08816 | ENTREZGENE, UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2019-04-02 | Wasl | WASP like actin nucleation promoting factor | Wasl | Wiskott-Aldrich syndrome-like | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2013-05-24 | Wasl | Wiskott-Aldrich syndrome-like | LOC685687 | hypothetical protein LOC685687 | Data Merged | 1643240 | APPROVED |
| 2009-12-15 | Wasl | Wiskott-Aldrich syndrome-like | Iqub | IQ motif and ubiquitin domain containing | Data Merged | 737654 | APPROVED |
| 2008-09-22 | Wasl | Wiskott-Aldrich syndrome-like | LOC682507 | similar to Neural Wiskott-Aldrich syndrome protein (N-WASP) | Data Merged | 737654 | APPROVED |
| 2008-03-04 | Wasl | Wiskott-Aldrich syndrome-like | Iqub | IQ motif and ubiquitin domain containing | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2007-11-07 | Iqub | IQ motif and ubiquitin domain containing | Wasl | Wiskott-Aldrich syndrome-like (human) | Symbol and Name updated | 1299863 | APPROVED |
| 2006-11-20 | LOC682507 | similar to Neural Wiskott-Aldrich syndrome protein (N-WASP) | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
| 2006-11-20 | LOC685687 | hypothetical protein LOC685687 | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
| 2005-07-08 | Wasl | Wiskott-Aldrich syndrome-like (human) | N-WASP | neural Wiskott-Aldrich syndrome protein | Symbol and Name updated | 1299863 | APPROVED |
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| More on Wasl | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 735144 |
| Created: | 2004-02-05 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-08-20 |
| Status: | ACTIVE |
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.
