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Gene: Wasl (WASP like actin nucleation promoting factor) Mus musculus
Symbol: Wasl
Name: WASP like actin nucleation promoting factor
RGD ID: 1553011
Description: Predicted to have cytoskeletal protein binding activity and identical protein binding activity. Involved in several processes, including cellular protein-containing complex localization; dendritic spine morphogenesis; and spindle localization. Localizes to actin cap and lamellipodium. Is expressed in brain; genitourinary system; liver; and spleen. Used to study atopic dermatitis. Orthologous to human WASL (WASP like actin nucleation promoting factor); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900021I12Rik; 3110031I02Rik; N-; N-WASP; neural Wiskott-Aldrich syndrome protein; Wiskott-Aldrich syndrome-like; Wiskott-Aldrich syndrome-like (human)
Homo sapiens (human) : WASL (WASP like actin nucleation promoting factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Wasl (WASP like actin nucleation promoting factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wasl (WASP like actin nucleation promoting factor)
Pan paniscus (bonobo/pygmy chimpanzee) : WASL (WASP like actin nucleation promoting factor)
Canis lupus familiaris (dog) : WASL (WASP like actin nucleation promoting factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wasl (WASP like actin nucleation promoting factor)
Sus scrofa (pig) : WASL (WASP like actin nucleation promoting factor)
Chlorocebus sabaeus (African green monkey) : WASL (WASP like actin nucleation promoting factor)
Heterocephalus glaber (naked mole-rat) : Wasl (WASP like actin nucleation promoting factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39624,613,809 - 24,665,185 (-)NCBI
GRCm38624,613,810 - 24,664,995 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl624,613,805 - 24,665,009 (-)EnsemblGRCm38mm10GRCm38
MGSCv37624,563,810 - 24,614,995 (-)NCBIGRCm37mm9NCBIm37
MGSCv36624,563,815 - 24,614,981 (-)NCBImm8
Celera624,624,846 - 24,676,054 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Wasl
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553011
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.