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Gene: Wasl (WASP like actin nucleation promoting factor) Mus musculus
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Symbol: Wasl
Name: WASP like actin nucleation promoting factor
RGD ID: 1553011
Description: Predicted to have cytoskeletal protein binding activity and identical protein binding activity. Involved in several processes, including cellular protein-containing complex localization; dendritic spine morphogenesis; and spindle localization. Localizes to actin cap and lamellipodium. Is expressed in brain; genitourinary system; liver; and spleen. Used to study atopic dermatitis. Orthologous to human WASL (WASP like actin nucleation promoting factor); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900021I12Rik; 3110031I02Rik; N-; N-WASP; neural Wiskott-Aldrich syndrome protein; Wiskott-Aldrich syndrome-like; Wiskott-Aldrich syndrome-like (human)
Orthologs:
Homo sapiens (human) : WASL (WASP like actin nucleation promoting factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Wasl (WASP like actin nucleation promoting factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wasl (WASP like actin nucleation promoting factor)
Pan paniscus (bonobo/pygmy chimpanzee) : WASL (WASP like actin nucleation promoting factor)
Canis lupus familiaris (dog) : WASL (WASP like actin nucleation promoting factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wasl (WASP like actin nucleation promoting factor)
Sus scrofa (pig) : WASL (WASP like actin nucleation promoting factor)
Chlorocebus sabaeus (African green monkey) : WASL (WASP like actin nucleation promoting factor)
Heterocephalus glaber (naked mole-rat) : Wasl (WASP like actin nucleation promoting factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39624,613,809 - 24,665,185 (-)NCBI
GRCm38624,613,810 - 24,664,995 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl624,613,805 - 24,665,009 (-)EnsemblGRCm38mm10GRCm38
MGSCv37624,563,810 - 24,614,995 (-)NCBIGRCm37mm9NCBIm37
MGSCv36624,563,815 - 24,614,981 (-)NCBImm8
Celera624,624,846 - 24,676,054 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Wasl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553011
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.