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GENE - TERM ANNOTATION REPORT

6 Annotations Found.

An association has been curated linking Cyp2e1 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with CYP2E1 (Homo sapiens) [(EXP) inferred from experiment]
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 91 papers in RGD have been used to annotate Cyp2e1
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:12668988 PMID:16770646 PMID:21741958 PMID:28762043


    • An association has been curated linking Cyp2e1 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Yanagiba Y, etal., Toxicol Ind Health. 2016 Sep;32(9):1589-97. doi: 10.1177/0748233714568801. Epub 2015 Feb 13.
  • The annotation has been inferred from sequence orthology with Cyp2e1 (Mus musculus) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Yanagiba Y, etal., Toxicol Ind Health. 2016 Sep;32(9):1589-97. doi: 10.1177/0748233714568801. Epub 2015 Feb 13.
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 91 papers in RGD have been used to annotate Cyp2e1


    • An association has been curated linking Cyp2e1 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Xu J, etal., Hepatol Commun. 2017 Oct 30;1(10):1043-1057. doi: 10.1002/hep4.1115. eCollection 2017 Dec.
  • The annotation has been inferred from sequence orthology with CYP2E1 (Homo sapiens) [(IMP) inferred from mutant phenotype]
  • 8 additional annotations were made from Xu J, etal., Hepatol Commun. 2017 Oct 30;1(10):1043-1057. doi: 10.1002/hep4.1115. eCollection 2017 Dec.
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 91 papers in RGD have been used to annotate Cyp2e1


    • An association has been curated linking Cyp2e1 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Zhang J, etal., Int J Environ Res Public Health. 2016 Aug 1;13(8). pii: ijerph13080776. doi: 10.3390/ijerph13080776.
  • The annotation has been inferred from sequence orthology with CYP2E1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 5 additional annotations were made from Zhang J, etal., Int J Environ Res Public Health. 2016 Aug 1;13(8). pii: ijerph13080776. doi: 10.3390/ijerph13080776.
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 91 papers in RGD have been used to annotate Cyp2e1
  • Curation Notes: DNA:hypermethylation:promoter


    • An association has been curated linking Cyp2e1 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Hassan HM, etal., Antimicrob Agents Chemother. 2016 Aug 22;60(9):5285-93. doi: 10.1128/AAC.00854-16. Print 2016 Sep.
  • 2 additional annotations were made from Hassan HM, etal., Antimicrob Agents Chemother. 2016 Aug 22;60(9):5285-93. doi: 10.1128/AAC.00854-16. Print 2016 Sep.
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 91 papers in RGD have been used to annotate Cyp2e1
  • Curation Notes: associated with Endotoxemia


    • An association has been curated linking Cyp2e1 and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Al-Rasheed NM, etal., Arch Physiol Biochem. 2017 May;123(2):78-92. doi: 10.1080/13813455.2016.1251945. Epub 2016 Dec 14.
  • 2 additional annotations were made from Al-Rasheed NM, etal., Arch Physiol Biochem. 2017 May;123(2):78-92. doi: 10.1080/13813455.2016.1251945. Epub 2016 Dec 14.
  • 445 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 91 papers in RGD have been used to annotate Cyp2e1
  • Qualifier: treatment


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