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Gene: Dsc2 (desmocollin 2) Rattus norvegicus
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Symbol: Dsc2
Name: desmocollin 2
Description: Predicted to have calcium ion binding activity. Predicted to be involved in cellular response to starvation and regulation of heart contraction. Predicted to localize to several cellular components, including the cytoplasmic vesicle; desmosome; and intercalated disc. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular dysplasia 11. Orthologous to human DSC2 (desmocollin 2); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: desmocollin-2; LOC291760; MGC124744
Orthologs:
Homo sapiens (human) : DSC2 (desmocollin 2)  HGNC  Alliance
Mus musculus (house mouse) : Dsc2 (desmocollin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dsc2 (desmocollin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DSC2 (desmocollin 2)
Canis lupus familiaris (dog) : DSC2 (desmocollin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dsc2 (desmocollin 2)
Sus scrofa (pig) : DSC2 (desmocollin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01811,826,705 - 11,858,801 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01811,625,847 - 11,658,036 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41811,902,185 - 11,933,989 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11811,930,689 - 11,960,686 (-)NCBI
Celera1811,467,743 - 11,499,764 (-)NCBICelera
Cytogenetic Map18p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dsc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309426
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.