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GENE - TERM ANNOTATION REPORT

3 Annotations Found.

An association has been curated linking Polg and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Hynynen J, etal., Liver Transpl. 2014 Nov;20(11):1402-12. doi: 10.1002/lt.23965. Epub 2014 Oct 3.
  • 2 additional annotations were made from Hynynen J, etal., Liver Transpl. 2014 Nov;20(11):1402-12. doi: 10.1002/lt.23965. Epub 2014 Oct 3.
  • 451 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 45 papers in RGD have been used to annotate Polg
  • Qualifier: susceptibility
  • Curation Notes: DNA:missense mutation:cds:p.W748S, p.E1143G (2243G>C, 3428A>G) (human)


    • An association has been curated linking Polg and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Hynynen J, etal., Epilepsia. 2018 Nov;59(11):2125-2136. doi: 10.1111/epi.14568. Epub 2018 Sep 26.
  • 2 additional annotations were made from Hynynen J, etal., Epilepsia. 2018 Nov;59(11):2125-2136. doi: 10.1111/epi.14568. Epub 2018 Sep 26.
  • 451 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 45 papers in RGD have been used to annotate Polg
  • Qualifier: no_association
  • Curation Notes: DNA:missense mutations:cds:p.Q1236H, p.E1143G (33708G>T, 3428A>G) (human)


    • An association has been curated linking Polg and Chemical and Drug Induced Liver Injury in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with POLG (Homo sapiens) [(EXP) inferred from experiment]
  • 451 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 45 papers in RGD have been used to annotate Polg
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:18208989 PMID:20138553


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